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CYBB

Index CYBB

Cytochrome b-245 heavy chain also known as cytochrome b(558) subunit beta or NADPH oxidase 2 or Nox2 is a protein that in humans is encoded by the CYBB gene. [1]

32 relations: Abdominal aorta, Angiotensin, Aortic arch, Atherosclerosis, Chronic granulomatous disease, Cytochrome b-245, alpha polypeptide, Descending thoracic aorta, Diabetic retinopathy, Encephalopathy, Extracellular signal–regulated kinases, Flavin adenine dinucleotide, Gene, GTPase, Heme, Hippocampus, Microbicide, Myocardial infarction, NADPH oxidase, Neuroinflammation, Neutrophil, Neutrophil cytosolic factor 1, Neutrophil cytosolic factor 2, Neutrophil cytosolic factor 4, Nicotinamide adenine dinucleotide phosphate, P22phox, Phagocyte, Podocyte, Protein, Reactive oxygen species, Sepsis, STAT3, Vacuole.

Abdominal aorta

The abdominal aorta is the largest artery in the abdominal cavity.

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Angiotensin

Angiotensin is a peptide hormone that causes vasoconstriction and an increase in blood pressure.

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Aortic arch

The aortic arch, arch of the aorta, or transverse aortic arch is the part of the aorta between the ascending and descending aorta.

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Atherosclerosis

Atherosclerosis is a disease in which the inside of an artery narrows due to the build up of plaque.

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Chronic granulomatous disease

Chronic granulomatous disease (CGD) (also known as Bridges–Good syndrome, chronic granulomatous disorder, and Quie syndrome) is a diverse group of hereditary diseases in which certain cells of the immune system have difficulty forming the reactive oxygen compounds (most importantly the superoxide radical due to defective phagocyte NADPH oxidase) used to kill certain ingested pathogens.

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Cytochrome b-245, alpha polypeptide

Cytochrome b-245 light chain is a protein that in humans is encoded by the CYBA gene involved in superoxide production and phagocytosis.

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Descending thoracic aorta

The descending thoracic aorta is a part of the aorta located in the thorax.

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Diabetic retinopathy

Diabetic retinopathy, also known as diabetic eye disease, is a medical condition in which damage occurs to the retina due to diabetes mellitus.

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Encephalopathy

Encephalopathy (from ἐγκέφαλος "brain" + πάθος "suffering") means any disorder or disease of the brain, especially chronic degenerative conditions.

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Extracellular signal–regulated kinases

In molecular biology, extracellular signal–regulated kinases (ERKs) or classical MAP kinases are widely expressed protein kinase intracellular signalling molecules that are involved in functions including the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells.

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Flavin adenine dinucleotide

In biochemistry, flavin adenine dinucleotide (FAD) is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.

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Gene

In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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GTPase

GTPases (singular GTPase) are a large family of hydrolase enzymes that can bind and hydrolyze guanosine triphosphate (GTP).

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Heme

Heme or haem is a coordination complex "consisting of an iron ion coordinated to a porphyrin acting as a tetradentate ligand, and to one or two axial ligands." The definition is loose, and many depictions omit the axial ligands.

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Hippocampus

The hippocampus (named after its resemblance to the seahorse, from the Greek ἱππόκαμπος, "seahorse" from ἵππος hippos, "horse" and κάμπος kampos, "sea monster") is a major component of the brains of humans and other vertebrates.

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Microbicide

A microbicide is any biocidal compound or substance whose purpose is to reduce the infectivity of microbes, such as viruses or bacteria.

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Myocardial infarction

Myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops to a part of the heart, causing damage to the heart muscle.

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NADPH oxidase

The NADPH oxidase (nicotinamide adenine dinucleotide phosphate-oxidase) is a membrane-bound enzyme complex that faces the extracellular space.

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Neuroinflammation

Neuroinflammation is inflammation of the nervous tissue.

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Neutrophil

Neutrophils (also known as neutrocytes) are the most abundant type of granulocytes and the most abundant (40% to 70%) type of white blood cells in most mammals.

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Neutrophil cytosolic factor 1

Neutrophil cytosol factor 1, also known as p47phox, is a protein that in humans is encoded by the NCF1 gene.

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Neutrophil cytosolic factor 2

Neutrophil cytosol factor 2 is a protein that in humans is encoded by the NCF2 gene.

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Neutrophil cytosolic factor 4

Neutrophil cytosol factor 4 is a protein that in humans is encoded by the NCF4 gene.

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Nicotinamide adenine dinucleotide phosphate

Nicotinamide adenine dinucleotide phosphate, abbreviated NADP or, in older notation, TPN (triphosphopyridine nucleotide), is a cofactor used in anabolic reactions, such as lipid and nucleic acid synthesis, which require NADPH as a reducing agent.

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P22phox

p22phox Protein, also known as the human neutrophil cytochrome b light chain (CYBA), is an essential component of the membrane-associated enzyme phagocyte NADPH-oxidaseDinauer MC, Pierce EA, Bruns GA, Curnutte JT, Orkin SH.

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Phagocyte

Phagocytes are cells that protect the body by ingesting harmful foreign particles, bacteria, and dead or dying cells.

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Podocyte

Podocytes are cells in the Bowman's capsule in the kidneys that wrap around capillaries of the glomerulus.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Reactive oxygen species

Reactive oxygen species (ROS) are chemically reactive chemical species containing oxygen.

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Sepsis

Sepsis is a life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs.

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STAT3

Signal transducer and activator of transcription 3 (STAT3) is a transcription factor which in humans is encoded by the STAT3 gene.

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Vacuole

A vacuole is a membrane-bound organelle which is present in all plant and fungal cells and some protist, animal and bacterial cells.

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Redirects here:

CYBB (gene), Gp91-PHOX, P91-PHOX.

References

[1] https://en.wikipedia.org/wiki/CYBB

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