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Paired box protein Pax-6, also known as aniridia type II protein (AN2) or oculorhombin, is a protein that in humans is encoded by the PAX6 gene. [1]

28 relations: Allen Brain Atlas, Aniridia, Anterior segment mesenchymal dysgenesis, BCL9, Bilateria, Cis-regulatory element, DNA-binding domain, Drosophila, Drosophila melanogaster, Ectoderm, Exon, Gene, Gene expression, Gillespie syndrome, Homeobox, Homology (biology), Mutation, Neurogenesis, Pax genes, Protein, Protein isoform, PYGO2, Sigurd Snake-in-the-Eye, Sonic hedgehog, Transcription (biology), Transcription factor, Transforming growth factor beta, Zygosity.

Allen Brain Atlas

The Allen Mouse and Human Brain Atlases are projects within the Allen Institute for Brain Science which seek to combine genomics with neuroanatomy by creating gene expression maps for the mouse and human brain.

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Aniridia is the absence of the iris, usually involving both eyes.

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Anterior segment mesenchymal dysgenesis

Anterior segment mesenchymal dysgenesis, or simply anterior segment dysgenesis (ASD), is a failure of the normal development of the tissues of the anterior segment of the eye.

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B-cell CLL/lymphoma 9 protein is a protein that in humans is encoded by the BCL9 gene.

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The Bilateria or bilaterians, or triploblasts, are animals with bilateral symmetry, i.e., they have a head (anterior) and a tail (posterior) as well as a back (dorsal) and a belly (ventral); therefore they also have a left side and a right side.

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Cis-regulatory element

Cis-regulatory elements (CREs) are regions of non-coding DNA which regulate the transcription of neighboring genes.

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DNA-binding domain

A DNA-binding domain (DBD) is an independently folded protein domain that contains at least one structural motif that recognizes double- or single-stranded DNA.

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Drosophila is a genus of flies, belonging to the family Drosophilidae, whose members are often called "small fruit flies" or (less frequently) pomace flies, vinegar flies, or wine flies, a reference to the characteristic of many species to linger around overripe or rotting fruit.

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Drosophila melanogaster

Drosophila melanogaster is a species of fly (the taxonomic order Diptera) in the family Drosophilidae.

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Ectoderm is one of the three primary germ layers in the very early embryo.

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An exon is any part of a gene that will encode a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing.

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In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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Gene expression

Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product.

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Gillespie syndrome

Gillespie syndrome, also called aniridia, cerebellar ataxia and mental deficiency. is a rare genetic disorder.

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A homeobox is a DNA sequence, around 180 base pairs long, found within genes that are involved in the regulation of patterns of anatomical development (morphogenesis) in animals, fungi and plants.

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Homology (biology)

In biology, homology is the existence of shared ancestry between a pair of structures, or genes, in different taxa.

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In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements.

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Neurogenesis is the process by which nervous system cells, known as neurons, are produced by neural stem cells (NSC)s, and it occurs in all species of animals except the porifera (sponges) and placozoans.

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Pax genes

In evolutionary developmental biology, Paired box (Pax) genes are a family of genes coding for tissue specific transcription factors containing a paired domain and usually a partial, or in the case of four family members (PAX3, PAX4, PAX6 and PAX7), a complete homeodomain.

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Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Protein isoform

A protein isoform, or "protein variant" is a member of a set of highly similar proteins that originate from a single gene or gene family and are the result of genetic differences.

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Pygopus homolog 2 is a protein that in humans is encoded by the PYGO2 gene.

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Sigurd Snake-in-the-Eye

Sigurd Snake-in-the-eye (Old Norse: Sigurðr ormr í auga) was a Viking warrior in the middle of the 9th Century.

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Sonic hedgehog

Sonic hedgehog is a protein that in humans is encoded by the SHH ("sonic hedgehog") gene.

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Transcription (biology)

Transcription is the first step of gene expression, in which a particular segment of DNA is copied into RNA (especially mRNA) by the enzyme RNA polymerase.

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Transcription factor

In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.

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Transforming growth factor beta

Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes four different isoforms (TGF-β 1 to 4, HGNC symbols TGFB1, TGFB2, TGFB3, TGFB4) and many other signaling proteins produced by all white blood cell lineages.

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Zygosity is the degree of similarity of the alleles for a trait in an organism.

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Redirects here:

Eyeless, Eyeless (gene), Eyeless gene, PAX-6, PAX6 (gene), Pax-6, Pax6.


[1] https://en.wikipedia.org/wiki/PAX6

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