PF-3845

PF-3845 is a selective inhibitor of fatty acid amide hydrolase. ^[1]

10 relations: Anandamide, Anti-inflammatory, Antidiarrhoeal, Cannabinoid, Colitis, Enzyme inhibitor, Fatty acid amide hydrolase, Mouse, Nociception, Receptor (biochemistry).

Anandamide

Anandamide, also known as N-arachidonoylethanolamine or AEA, is a fatty acid neurotransmitter derived from the non-oxidative metabolism of eicosatetraenoic acid (arachidonic acid) an essential ω-6 polyunsaturated fatty acid.

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Anti-inflammatory

Anti-inflammatory, or antiinflammatory, refers to the property of a substance or treatment that reduces inflammation or swelling.

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Antidiarrhoeal

An anti-diarrhoeal drug (or anti-diarrheal drug in American English) is any medication which provides symptomatic relief for diarrhoea.

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Cannabinoid

A cannabinoid is one of a class of diverse chemical compounds that acts on cannabinoid receptors in cells that alter neurotransmitter release in the brain.

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Colitis

Colitis is an inflammation of the colon.

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Enzyme inhibitor

4QI9) An enzyme inhibitor is a molecule that binds to an enzyme and decreases its activity.

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Fatty acid amide hydrolase

Fatty acid amide hydrolase or FAAH (oleamide hydrolase, anandamide amidohydrolase) is a member of the serine hydrolase family of enzymes.

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Mouse

A mouse (Mus), plural mice, is a small rodent characteristically having a pointed snout, small rounded ears, a body-length scaly tail and a high breeding rate.

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Nociception

Nociception (also nocioception or nociperception, from Latin nocere 'to harm or hurt') is the sensory nervous system's response to certain harmful or potentially harmful stimuli.

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Receptor (biochemistry)

In biochemistry and pharmacology, a receptor is a protein molecule that receives chemical signals from outside a cell.

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References

[1] https://en.wikipedia.org/wiki/PF-3845

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