5 relations: AKR1C3, Cancer, Hypoxia-activated prodrug, Nitrogen mustard, Tumor hypoxia.
AKR1C3
Aldo-keto reductase family 1 member C3 (AKR1C3), also known as 17β-hydroxysteroid dehydrogenase type 5 (17β-HSD5, HSD17B5) is a key steroidogenic enzyme that in humans is encoded by the AKR1C3 gene.
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Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.
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Hypoxia-activated prodrug
Hypoxia-Activated Prodrugs (HAPs) are prodrugs that target regions of tumor hypoxia within tumor cells.
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Nitrogen mustard
Nitrogen mustards are cytotoxic chemotherapy agents derived from mustard gas.
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Tumor hypoxia
Tumor hypoxia is the situation where tumor cells have been deprived of oxygen.
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