14 relations: Cleft lip and cleft palate, Gene, Holoprosencephaly, Medulloblastoma, Nevoid basal-cell carcinoma syndrome, Patched, Protein, Smoothened, Sonic hedgehog, Squamous cell carcinoma, Transitional cell carcinoma, Transmembrane protein, Trichoepithelioma, Tumor suppressor.
Cleft lip and cleft palate
Cleft lip and cleft palate, also known as orofacial cleft, is a group of conditions that includes cleft lip (CL), cleft palate (CP), and both together (CLP).
New!!: PTCH1 and Cleft lip and cleft palate · See more »
Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
New!!: PTCH1 and Gene · See more »
Holoprosencephaly
Holoprosencephaly (HPE) is a cephalic disorder in which the prosencephalon (the forebrain of the embryo) fails to develop into two hemispheres.
New!!: PTCH1 and Holoprosencephaly · See more »
Medulloblastoma
Medulloblastoma is the most common type of pediatric malignant primary brain tumor (cancer), originating in the part of the brain that is towards the back and the bottom, on the floor of the skull, in the cerebellum, or posterior fossa.
New!!: PTCH1 and Medulloblastoma · See more »
Nevoid basal-cell carcinoma syndrome
Nevoid basal-cell carcinoma syndrome (NBCCS), also known as basal-cell nevus syndrome, multiple basal-cell carcinoma syndrome, Gorlin syndrome, and Gorlin–Goltz syndrome, is an inherited medical condition involving defects within multiple body systems such as the skin, nervous system, eyes, endocrine system, and bones.
New!!: PTCH1 and Nevoid basal-cell carcinoma syndrome · See more »
Patched
Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates.
New!!: PTCH1 and Patched · See more »
Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
New!!: PTCH1 and Protein · See more »
Smoothened
Smoothened is a protein that in humans is encoded by the SMO gene.
New!!: PTCH1 and Smoothened · See more »
Sonic hedgehog
Sonic hedgehog is a protein that in humans is encoded by the SHH ("sonic hedgehog") gene.
New!!: PTCH1 and Sonic hedgehog · See more »
Squamous cell carcinoma
Squamous cell carcinomas, also known as epidermoid carcinoma are a number of different types of cancer that result from squamous cells.
New!!: PTCH1 and Squamous cell carcinoma · See more »
Transitional cell carcinoma
Transitional cell carcinoma, also urothelial carcinoma, is a type of cancer that typically occurs in the urinary system.
New!!: PTCH1 and Transitional cell carcinoma · See more »
Transmembrane protein
A transmembrane protein (TP) is a type of integral membrane protein that spans the entirety of the biological membrane to which it is permanently attached.
New!!: PTCH1 and Transmembrane protein · See more »
Trichoepithelioma
Trichoepithelioma is a neoplasm of the adnexa of the skin.
New!!: PTCH1 and Trichoepithelioma · See more »
Tumor suppressor
A tumor suppressor gene, or antioncogene, is a gene that protects a cell from one step on the path to cancer.
New!!: PTCH1 and Tumor suppressor · See more »