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Pulmonary venoocclusive disease

Index Pulmonary venoocclusive disease

Pulmonary veno-occlusive disease (PVOD) is a rare form of pulmonary hypertension caused by progressive blockage of the small veins in the lungs. [1]

34 relations: Bleomycin, Blood vessel, Breathing, Capillary, Carmustine, Chemotherapy, Chest pain, Chloe Temtchine, Connective tissue disease, CT scan, Cyanosis, Edema, EIF2AK4, Endothelin receptor antagonist, Fatigue, Fiber, Germline, Ground-glass opacity, Heart failure, Hematopoietic stem cell transplantation, Hemoptysis, HIV/AIDS, Lobe (anatomy), Lumen (anatomy), Lung transplantation, Lymphatic vessel, Mediastinal lymphadenopathy, Mitomycins, Mutation, Pleural effusion, Prostacyclin, Pulmonary edema, Pulmonary hypertension, Pulmonary vein.

Bleomycin

Bleomycin is a medication used to treat cancer. This includes Hodgkin's lymphoma, non-Hodgkin's lymphoma, testicular cancer, ovarian cancer, and cervical cancer among others. Typically used with other cancer medications, it can be given intravenously, by injection into a muscle or under the skin. It may also be administered inside the chest to help prevent the recurrence of a fluid around the lung due to cancer; however talc is better for this. Common side effects include fever, weight loss, vomiting, and rash. A severe type of anaphylaxis may occur. It may also cause inflammation of the lungs that can result in lung scarring. Chest X-rays every couple of weeks are recommended to check for this. Bleomycin may cause harm to the baby if used during pregnancy. It is believed to primarily work by preventing the making of DNA. Bleomycin was discovered in 1962. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. It is available as a generic medication. The wholesale cost in the developing world is between 14 USD and 78 USD a dose. It is made by the bacterium Streptomyces verticillus.

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Blood vessel

The blood vessels are the part of the circulatory system, and microcirculation, that transports blood throughout the human body.

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Breathing

Breathing (or respiration, or ventilation) is the process of moving air into and out of the lungs to facilitate gas exchange with the internal environment, mostly by bringing in oxygen and flushing out carbon dioxide.

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Capillary

A capillary is a small blood vessel from 5 to 10 micrometres (µm) in diameter, and having a wall one endothelial cell thick.

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Carmustine

Carmustine (bis-chloroethylnitrosourea, BCNU, BiCNU) is a medication used mainly for chemotherapy It is a nitrogen mustard β-chloro-nitrosourea compound used as an alkylating agent.

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Chemotherapy

Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen.

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Chest pain

Chest pain is pain in any region of the chest.

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Chloe Temtchine

Chloe Temtchine is an American singer-songwriter.

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Connective tissue disease

A connective tissue disease is any disease that has the connective tissues of the body as a target of pathology.

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CT scan

A CT scan, also known as computed tomography scan, makes use of computer-processed combinations of many X-ray measurements taken from different angles to produce cross-sectional (tomographic) images (virtual "slices") of specific areas of a scanned object, allowing the user to see inside the object without cutting.

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Cyanosis

Cyanosis is defined as the bluish or purplish discolouration of the skin or mucous membranes due to the tissues near the skin surface having low oxygen saturation.

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Edema

Edema, also spelled oedema or œdema, is an abnormal accumulation of fluid in the interstitium, located beneath the skin and in the cavities of the body, which can cause severe pain.

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EIF2AK4

Eukaryotic translation initiation factor 2-alpha kinase 4 is an enzyme that in humans is encoded by the EIF2AK4 gene.

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Endothelin receptor antagonist

An endothelin receptor antagonist (ERA) is a drug that blocks endothelin receptors.

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Fatigue

Fatigue is a subjective feeling of tiredness that has a gradual onset.

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Fiber

Fiber or fibre (see spelling differences, from the Latin fibra) is a natural or synthetic substance that is significantly longer than it is wide.

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Germline

In biology and genetics, the germline in a multicellular organism is the population of its bodily cells that are so differentiated or segregated that in the usual processes of reproduction they may pass on their genetic material to the progeny.

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Ground-glass opacity

In radiology, ground glass opacity (GGO) is a nonspecific finding on computed tomography (CT) scans that indicates a partial filling of air spaces in the lungs by exudate or transudate, as well as interstitial thickening or partial collapse of lung alveoli.

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Heart failure

Heart failure (HF), often referred to as congestive heart failure (CHF), is when the heart is unable to pump sufficiently to maintain blood flow to meet the body's needs.

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Hematopoietic stem cell transplantation

Hematopoietic stem cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood.

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Hemoptysis

Hemoptysis is the coughing up of blood or blood-stained mucus from the bronchi, larynx, trachea, or lungs.

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HIV/AIDS

Human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV).

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Lobe (anatomy)

In anatomy, a lobe is a clear anatomical division or extension of an organ (as seen for example in the brain, the lung, liver or the kidney) that can be determined without the use of a microscope at the gross anatomy level.

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Lumen (anatomy)

In biology, a lumen (plural lumina) is the inside space of a tubular structure, such as an artery or intestine.

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Lung transplantation

Lung transplantation or pulmonary transplantation is a surgical procedure in which a patient's diseased lungs are partially or totally replaced by lungs which come from a donor.

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Lymphatic vessel

The lymphatic vessels (or lymph vessels or lymphatics) are thin-walled vessels structured like blood vessels, that carry lymph.

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Mediastinal lymphadenopathy

Mediastinal lymphadenopathy or mediastinal adenopathy is an enlargement of the mediastinal lymph nodes.

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Mitomycins

The mitomycins are a family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae. They include mitomycin A, mitomycin B, and mitomycin C. When the name mitomycin occurs alone, it usually refers to mitomycin C, its international nonproprietary name.

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Mutation

In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements.

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Pleural effusion

A pleural effusion is excess fluid that accumulates in the pleural cavity, the fluid-filled space that surrounds the lungs.

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Prostacyclin

Prostacyclin (also called prostaglandin I2 or PGI2) is a prostaglandin member of the eicosanoid family of lipid molecules.

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Pulmonary edema

Pulmonary edema is fluid accumulation in the tissue and air spaces of the lungs.

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Pulmonary hypertension

Pulmonary hypertension (PH or PHTN) is a condition of increased blood pressure within the arteries of the lungs.

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Pulmonary vein

The pulmonary veins are the veins that transfer oxygenated blood from the lungs to the heart.

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PVOD, Pulmonary veno occlusive disease, Pulmonary veno-occlusive disease.

References

[1] https://en.wikipedia.org/wiki/Pulmonary_venoocclusive_disease

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