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50 relations: Adenomatous polyposis coli, Adipose tissue, Agonist, AMP-activated protein kinase, ANGPTL4, Arachidonic acid, Beta-catenin, Brain, Cancer, CD36, Cell (journal), Colorectal cancer, Corpus callosum, Epidermis, Gene, Gene expression, Gonad, GW0742, GW501516, HDAC3, Heart, Hyperplasia, Infant, Keratinocyte, Knockout mouse, Large intestine, Liver, Lung, Myelin, Nuclear receptor, Nuclear receptor co-repressor 2, Oxidative phosphorylation, PDK4, Perilipin-2, Peroxisome proliferator-activated receptor, Postpartum period, Protein mimetic, Protein–protein interaction, Repressor, Scientific consensus, Skeletal muscle, Small intestine, Spleen, Telmisartan, Thymus, Transcription (biology), Uncoupling protein, Xenopus, 12-O-Tetradecanoylphorbol-13-acetate, 15-Hydroxyeicosatetraenoic acid.
Adenomatous polyposis coli
Adenomatous polyposis coli (APC) also known as deleted in polyposis 2.5 (DP2.5) is a protein that in humans is encoded by the APC gene.
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Adipose tissue
In biology, adipose tissue, body fat, or simply fat is a loose connective tissue composed mostly of adipocytes.
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Agonist
An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.
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AMP-activated protein kinase
5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme (EC 2.7.11.31) that plays a role in cellular energy homeostasis.
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ANGPTL4
Angiopoietin-like 4 is a protein that in human is encoded by the ANGPTL4 gene.
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Arachidonic acid
Arachidonic acid (AA, sometimes ARA) is a polyunsaturated omega-6 fatty acid 20:4(ω-6).
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Beta-catenin
Catenin beta-1, also known as β-catenin, is a protein that in humans is encoded by the CTNNB1 gene.
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Brain
The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals.
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Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.
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CD36
CD36 (cluster of differentiation 36), also known as platelet glycoprotein 4, fatty acid translocase (FAT), scavenger receptor class B member 3 (SCARB3), and glycoproteins 88 (GP88), IIIb (GPIIIB), or IV (GPIV) is a protein that in humans is encoded by the CD36 gene.
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Cell (journal)
Cell is a peer-reviewed scientific journal publishing research papers across a broad range of disciplines within the life sciences.
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Colorectal cancer
Colorectal cancer (CRC), also known as bowel cancer and colon cancer, is the development of cancer from the colon or rectum (parts of the large intestine).
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Corpus callosum
The corpus callosum (Latin for "tough body"), also callosal commissure, is a wide commissure, a flat bundle of commissural fibers, about 10 cm long beneath the cerebral cortex in the brains of placental mammals.
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Epidermis
The epidermis is the outer layer of the three layers that make up the skin, the inner layers being the dermis and hypodermis.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Gene expression
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product.
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Gonad
A gonad or sex gland or reproductive gland is a mixed gland that produces the gametes (sex cells) and sex hormones of an organism.
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GW0742
GW0742 (also known as GW610742) is a PPARδ/β agonist that is investigated for drug use by GlaxoSmithKline.
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GW501516
GW501516 (also known as GW-501,516, GW1516, GSK-516 and on the black market as Endurobol) is a PPARδ receptor agonist that was invented in a collaboration between Ligand Pharmaceuticals and GlaxoSmithKline in the 1990s, was entered into clinical development as a drug candidate for metabolic diseases and cardiovascular diseases, and was abandoned in 2007 because animal testing showed that the drug caused cancer to develop rapidly in several organs.
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HDAC3
Histone deacetylase 3 is an enzyme encoded by the HDAC3 gene in both humans and mice.
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Heart
The heart is a muscular organ in most animals, which pumps blood through the blood vessels of the circulatory system.
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Hyperplasia
Hyperplasia (from ancient Greek ὑπέρ huper, "over" + πλάσις plasis, "formation"), or hypergenesis, is an increase in the amount of organic tissue that results from cell proliferation.
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Infant
An infant (from the Latin word infans, meaning "unable to speak" or "speechless") is the more formal or specialised synonym for "baby", the very young offspring of a human.
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Keratinocyte
A keratinocyte is the predominant cell type in the epidermis, the outermost layer of the skin, constituting 90% of the cells found there.
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Knockout mouse
A knockout mouse or knock-out mouse is a genetically modified mouse (Mus musculus) in which researchers have inactivated, or "knocked out", an existing gene by replacing it or disrupting it with an artificial piece of DNA.
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Large intestine
The large intestine, also known as the large bowel or colon, is the last part of the gastrointestinal tract and of the digestive system in vertebrates.
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Liver
The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.
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Lung
The lungs are the primary organs of the respiratory system in humans and many other animals including a few fish and some snails.
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Myelin
Myelin is a lipid-rich substance that surrounds the axon of some nerve cells, forming an electrically insulating layer.
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Nuclear receptor
In the field of molecular biology, nuclear receptors are a class of proteins found within cells that are responsible for sensing steroid and thyroid hormones and certain other molecules.
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Nuclear receptor co-repressor 2
The nuclear receptor co-repressor 2 is a transcriptional coregulatory protein that contains several nuclear receptor-interacting domains.
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Oxidative phosphorylation
Oxidative phosphorylation (or OXPHOS in short) (UK, US) is the metabolic pathway in which cells use enzymes to oxidize nutrients, thereby releasing energy which is used to produce adenosine triphosphate (ATP).
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PDK4
Pyruvate dehydrogenase lipoamide kinase isozyme 4, mitochondrial is an enzyme that in humans is encoded by the PDK4 gene.
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Perilipin-2
Adipose differentiation-related protein, also known as perilipin 2, ADRP or adipophilin, is a protein which belongs from PAT family of cytoplasmic lipid droplet(CLD) binding protein.
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Peroxisome proliferator-activated receptor
In the field of molecular biology, the peroxisome proliferator-activated receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes.
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Postpartum period
A postpartum (or postnatal) period begins immediately after the birth of a child as the mother's body, including hormone levels and uterus size, returns to a non-pregnant state.
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Protein mimetic
A protein mimetic is a molecule such as a peptide, a modified peptide or any other molecule that biologically mimics the action or activity of some other protein.
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Protein–protein interaction
Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.
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Repressor
In molecular genetics, a repressor is a DNA- or RNA-binding protein that inhibits the expression of one or more genes by binding to the operator or associated silencers.
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Scientific consensus
Scientific consensus is the collective judgment, position, and opinion of the community of scientists in a particular field of study.
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Skeletal muscle
Skeletal muscle is one of three major muscle types, the others being cardiac muscle and smooth muscle.
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Small intestine
The small intestine or small bowel is the part of the gastrointestinal tract between the stomach and the large intestine, and is where most of the end absorption of food takes place.
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Spleen
The spleen is an organ found in virtually all vertebrates.
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Telmisartan
Telmisartan (INN) is an angiotensin II receptor antagonist (angiotensin receptor blocker, ARB) used in the management of hypertension.
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Thymus
The thymus is a specialized primary lymphoid organ of the immune system.
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Transcription (biology)
Transcription is the first step of gene expression, in which a particular segment of DNA is copied into RNA (especially mRNA) by the enzyme RNA polymerase.
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Uncoupling protein
An uncoupling protein (UCP) is a mitochondrial inner membrane protein that is a regulated proton channel or transporter.
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Xenopus
Xenopus (Gk., ξενος, xenos.
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12-O-Tetradecanoylphorbol-13-acetate
12-O-Tetradecanoylphorbol-13-acetate (TPA), also commonly known as tetradecanoylphorbol acetate, tetradecanoyl phorbol acetate, and phorbol 12-myristate 13-acetate (PMA), is a diester of phorbol and a potent tumor promoter often employed in biomedical research to activate the signal transduction enzyme protein kinase C (PKC).
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15-Hydroxyeicosatetraenoic acid
15-Hydroxyeicosatetraenoic acid (also termed 15-HETE, 15(S)-HETE, and 15S-HETE) is an eicosanoid, i.e. a metabolite of arachidonic acid.
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Redirects here:
NR1C2, PPAR-beta, PPAR-delta, PPARD, PPARD (gene), PPARδ, Peroxisome proliferative activated receptor, delta, Peroxisome proliferator-activated receptor beta.
References
[1] https://en.wikipedia.org/wiki/Peroxisome_proliferator-activated_receptor_delta
