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Phi X 174

Index Phi X 174

The phi X 174 (or ΦX174) bacteriophage is a single-stranded DNA (ssDNA) virus and the first DNA-based genome to be sequenced. [1]

32 relations: Arthur Kornberg, Bacteriophage, Bacteriophage MS2, Bioinformatics, Capsid, Coiled coil, Craig Venter, DNA, DNA polymerase, DNA sequencing, DNA virus, Escherichia coli, Frederick Sanger, GC-content, Genome, Glycine, Helicase, Lipopolysaccharide, Lysis, Microviridae, Microvirus, Morphogenesis, Nucleotide, Overlapping gene, Primosome, Protein, Rolling circle replication, Single-stranded binding protein, Stoichiometry, Synthetic biology, Transmembrane domain, Walter Fiers.

Arthur Kornberg

Arthur Kornberg (March 3, 1918 – October 26, 2007) was an American biochemist who won the Nobel Prize in Physiology or Medicine 1959 for his discovery of "the mechanisms in the biological synthesis of deoxyribonucleic acid (DNA)" together with Dr.

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Bacteriophage

A bacteriophage, also known informally as a phage, is a virus that infects and replicates within Bacteria and Archaea.

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Bacteriophage MS2

The bacteriophage MS2 is an icosahedral, positive-sense single-stranded RNA virus that infects the bacterium Escherichia coli and other members of the Enterobacteriaceae.

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Bioinformatics

Bioinformatics is an interdisciplinary field that develops methods and software tools for understanding biological data.

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Capsid

A capsid is the protein shell of a virus.

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Coiled coil

A coiled coil is a structural motif in proteins in which 2–7 alpha-helices are coiled together like the strands of a rope (dimers and trimers are the most common types).

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Craig Venter

John Craig Venter (born October 14, 1946) is an American biotechnologist, biochemist, geneticist, and businessman.

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DNA

Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.

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DNA polymerase

DNA polymerases are enzymes that synthesize DNA molecules from deoxyribonucleotides, the building blocks of DNA.

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DNA sequencing

DNA sequencing is the process of determining the precise order of nucleotides within a DNA molecule.

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DNA virus

A DNA virus is a virus that has DNA as its genetic material and replicates using a DNA-dependent DNA polymerase.

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Escherichia coli

Escherichia coli (also known as E. coli) is a Gram-negative, facultatively anaerobic, rod-shaped, coliform bacterium of the genus Escherichia that is commonly found in the lower intestine of warm-blooded organisms (endotherms).

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Frederick Sanger

Frederick Sanger (13 August 1918 – 19 November 2013) was a British biochemist who twice won the Nobel Prize in Chemistry, one of only two people to have done so in the same category (the other is John Bardeen in physics), the fourth person overall with two Nobel Prizes, and the third person overall with two Nobel Prizes in the sciences.

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GC-content

In molecular biology and genetics, GC-content (or guanine-cytosine content) is the percentage of nitrogenous bases on a DNA or RNA molecule that are either guanine or cytosine (from a possibility of four different ones, also including adenine and thymine in DNA and adenine and uracil in RNA).

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Genome

In the fields of molecular biology and genetics, a genome is the genetic material of an organism.

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Glycine

Glycine (symbol Gly or G) is the amino acid that has a single hydrogen atom as its side chain.

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Helicase

Helicases are a class of enzymes vital to all living organisms.

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Lipopolysaccharide

Lipopolysaccharides (LPS), also known as lipoglycans and endotoxins, are large molecules consisting of a lipid and a polysaccharide composed of O-antigen, outer core and inner core joined by a covalent bond; they are found in the outer membrane of Gram-negative bacteria.

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Lysis

Lysis (Greek λύσις lýsis, "a loosing" from λύειν lýein, "to unbind") refers to the breaking down of the membrane of a cell, often by viral, enzymic, or osmotic (that is, "lytic") mechanisms that compromise its integrity.

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Microviridae

Microviridae is a family of bacteriophages with a single-stranded DNA genome.

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Microvirus

Microvirus is a genus of viruses, in the family Microviridae.

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Morphogenesis

Morphogenesis (from the Greek morphê shape and genesis creation, literally, "beginning of the shape") is the biological process that causes an organism to develop its shape.

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Nucleotide

Nucleotides are organic molecules that serve as the monomer units for forming the nucleic acid polymers deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essential biomolecules within all life-forms on Earth.

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Overlapping gene

An overlapping gene is a gene whose expressible nucleotide sequence partially overlaps with the expressible nucleotide sequence of another gene.

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Primosome

In molecular biology, a primosome is a protein complex responsible for creating RNA primers on single stranded DNA during DNA replication.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Rolling circle replication

Rolling circle replication describes a process of unidirectional nucleic acid replication that can rapidly synthesize multiple copies of circular molecules of DNA or RNA, such as plasmids, the genomes of bacteriophages, and the circular RNA genome of viroids.

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Single-stranded binding protein

Single-stranded binding proteins (SSBs) are a class of proteins that have been identified in both viruses and organisms from bacteria to humans.

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Stoichiometry

Stoichiometry is the calculation of reactants and products in chemical reactions.

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Synthetic biology

Synthetic biology is an interdisciplinary branch of biology and engineering.

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Transmembrane domain

Transmembrane domain usually denotes a transmembrane segment of single alpha helix of a transmembrane protein.

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Walter Fiers

Walter Fiers (born 1931 in Ypres, West Flanders) is a Belgian molecular biologist.

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Redirects here:

Bacteriophage phX174, Bacteriophage phi-X174, Bacteriophage phiX174, Bacteriophage φX174, Bacteriophage ϕX174, Coliphage phiX174, Enterobacteria phage phiX174, Enterobacteria phage φX174, Ph-X174, Ph-X174 phage, PhX174, Phage phi-X174, Phi X, Phi X 174 phage, Phi X-174, Phi X174, Phi-X174, Phi-X174 phage, PhiX, PhiX-174, PhiX174, X174, Φ-X174, Φ-X174 phage, ΦX174.

References

[1] https://en.wikipedia.org/wiki/Phi_X_174

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