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Phenethylamine

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Phenethylamine (PEA) is an organic compound, natural monoamine alkaloid, and trace amine which acts as a central nervous system stimulant in humans. [1]

142 relations: Acyl chloride, Adrenaline, Aldehyde dehydrogenase, Alexander Shulgin, Alkaloid, Amino acid, Ammonia, Amphetamine, Anorectic, Antidepressant, Antihypotensive agent, Antimicrobial, Antiparkinson medication, AOC2, AOC3, Aralkylamine N-acetyltransferase, Aromatic L-amino acid decarboxylase, Attention deficit hyperactivity disorder, Bacteria, Base (chemistry), Benzene, Benzyl cyanide, Beta-Nitrostyrene, Biological target, Biomarker (medicine), Biosynthesis, Brain, Bronchodilator, Bupropion, Carbon dioxide, Carbonate, Catalysis, Catecholamine, Cathinone, Central nervous system, Chemical classification, Chocolate, Clostridium, Concentration, CYP2A6, Decarboxylation, Decongestant, Derivative (chemistry), Dietary supplement, Diethyl ether, Dopamine, EC50, Empathogen–entactogen, Endocytosis, Endogeny (biology), ..., Enterobacteriaceae, Enzyme, Ephedrine, Escherichia coli, Escherichia coli O157:H7, Ethanol, Ethyl group, Euphoria, Fanetizole, Fermentation in food processing, Flavin-containing monooxygenase 3, Friedel–Crafts reaction, Fungus, G protein–coupled receptor, Half-life, Hallucinogen, Heck reaction, Hormone, Hydrochloride, Hydrogen, Hydrogen atom, Hydrogenation, IC50, Isomer, Kidney, Lactobacillus, Lithium aluminium hydride, Locus coeruleus, MDMA, Methamphetamine, Methylphenidate, Microorganism, Monoamine neurotransmitter, Monoamine oxidase, Monoamine oxidase A, Monoamine oxidase B, Monoamine oxidase inhibitor, Monoamine releasing agent, Mood (psychology), N-Methylphenethylamine, Natural product, Neurobiological effects of physical exercise, Neuromodulation, Neurotransmitter, Norepinephrine, Oral administration, Organic compound, Organolithium reagent, Organozinc compound, Oxazolone, Parachuting, Pars compacta, Phenelzine, Phenformin, Phentermine, Phenyl group, Phenylacetaldehyde, Phenylacetic acid, Phenylalanine, Phenylethanolamine N-methyltransferase, Physical dependence, PiHKAL, Primary-amine oxidase, Protein kinase A, Protein kinase C, Pseudoephedrine, Pseudomonas, Psychedelic drug, Psychological dependence, Raney nickel, Salt (chemistry), Selegiline, Small intestine, Stimulant, Substituent, Substituted amphetamine, Substituted methylenedioxyphenethylamine, Substituted phenethylamine, Substitution reaction, Suzuki reaction, TAAR1, TAAR2, Therapeutic effect, Trace amine, Trace amine-associated receptor, Tyramine, Tyrosine, Ventral tegmental area, Vesicular monoamine transporter 2, Weight loss, 2,5-Dimethoxy-4-methylamphetamine, 3,4-Methylenedioxyamphetamine. Expand index (92 more) »

Acyl chloride

In organic chemistry, an acyl chloride (or acid chloride) is an organic compound with the functional group -COCl. Their formula is usually written RCOCl, where R is a side chain.

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Adrenaline

Adrenaline, also known as adrenalin or epinephrine, is a hormone, neurotransmitter, and medication.

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Aldehyde dehydrogenase

Aldehyde dehydrogenases are a group of enzymes that catalyse the oxidation of aldehydes.

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Alexander Shulgin

Alexander Theodore "Sasha" Shulgin (June 17, 1925 June 2, 2014) was an American medicinal chemist, biochemist, organic chemist, pharmacologist, psychopharmacologist, and author.

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Alkaloid

Alkaloids are a class of naturally occurring chemical compounds that mostly contain basic nitrogen atoms.

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Amino acid

Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.

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Ammonia

Ammonia is a compound of nitrogen and hydrogen with the formula NH3.

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Amphetamine

Amphetamine (contracted from) is a potent central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity.

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Anorectic

An anorectic or anorexic is a drug which reduces appetite, resulting in lower food consumption, leading to weight loss.

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Antidepressant

Antidepressants are drugs used for the treatment of major depressive disorder and other conditions, including dysthymia, anxiety disorders, obsessive–compulsive disorder, eating disorders, chronic pain, neuropathic pain and, in some cases, dysmenorrhoea, snoring, migraine, attention-deficit hyperactivity disorder (ADHD), addiction, dependence, and sleep disorders.

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Antihypotensive agent

An antihypotensive agent, also known as a vasopressor agent or pressor, is any medication that tends to raise reduced blood pressure.

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Antimicrobial

An antimicrobial is an agent that kills microorganisms or stops their growth.

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Antiparkinson medication

An antiparkinson medication is a type of drug which is intended to treat and relieve the symptoms of Parkinson's disease.

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AOC2

Amine oxidase, copper containing 2 is a protein that in humans is encoded by the AOC2 gene.

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AOC3

Amine oxidase, copper containing 3, also known as vascular adhesion protein (VAP-1) and HPAO is an enzyme that in humans is encoded by the AOC3 gene on chromosome 17.

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Aralkylamine N-acetyltransferase

Aralkylamine N-acetyltransferase (AANAT), also known as arylalkylamine N-acetyltransferase or serotonin N-acetyltransferase (SNAT), is an enzyme that is involved in the day/night rhythmic production of melatonin, by modification of serotonin.

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Aromatic L-amino acid decarboxylase

Aromatic L-amino acid decarboxylase (AADC or AAAD), also known as DOPA decarboxylase (DDC), tryptophan decarboxylase, and 5-hydroxytryptophan decarboxylase, is a lyase enzyme.

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Attention deficit hyperactivity disorder

Attention-deficit hyperactivity disorder (ADHD) is a mental disorder of the neurodevelopmental type.

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Bacteria

Bacteria (common noun bacteria, singular bacterium) is a type of biological cell.

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Base (chemistry)

In chemistry, bases are substances that, in aqueous solution, release hydroxide (OH−) ions, are slippery to the touch, can taste bitter if an alkali, change the color of indicators (e.g., turn red litmus paper blue), react with acids to form salts, promote certain chemical reactions (base catalysis), accept protons from any proton donor, and/or contain completely or partially displaceable OH− ions.

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Benzene

Benzene is an important organic chemical compound with the chemical formula C6H6.

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Benzyl cyanide

Benzyl cyanide (abbreviated BnCN) is an organic compound with the chemical formula C6H5CH2CN.

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Beta-Nitrostyrene

β-Nitrostyrene is an aromatic compound and a nitroalkene used in the synthesis of indigo dye and the slimicide bromo-nitrostyrene.

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Biological target

A biological target is anything within a living organism to which some other entity (like an endogenous ligand or a drug) is directed and/or binds, resulting in a change in its behavior or function.

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Biomarker (medicine)

In medicine, a biomarker is a measurable indicator of the severity or presence of some disease state.

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Biosynthesis

Biosynthesis (also called anabolism) is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms.

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Brain

The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals.

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Bronchodilator

A bronchodilator is a substance that dilates the bronchi and bronchioles, decreasing resistance in the respiratory airway and increasing airflow to the lungs.

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Bupropion

Bupropion, sold under the brand names Wellbutrin and Zyban among others, is a medication primarily used as an antidepressant and smoking cessation aid.

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Carbon dioxide

Carbon dioxide (chemical formula) is a colorless gas with a density about 60% higher than that of dry air.

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Carbonate

In chemistry, a carbonate is a salt of carbonic acid (H2CO3), characterized by the presence of the carbonate ion, a polyatomic ion with the formula of.

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Catalysis

Catalysis is the increase in the rate of a chemical reaction due to the participation of an additional substance called a catalysthttp://goldbook.iupac.org/C00876.html, which is not consumed in the catalyzed reaction and can continue to act repeatedly.

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Catecholamine

A catecholamine (CA) is a monoamine, an organic compound that has a catechol (benzene with two hydroxyl side groups at carbons 1 and 2) and a side-chain amine.

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Cathinone

Cathinone (also known as benzoylethanamine, or β-keto-amphetamine) is a monoamine alkaloid found in the shrub Catha edulis (khat) and is chemically similar to ephedrine, cathine, methcathinone and other amphetamines.

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Central nervous system

The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.

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Chemical classification

Chemical classification systems attempt to classify elements or compounds according to certain chemical functional or structural properties.

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Chocolate

Chocolate is a typically sweet, usually brown food preparation of Theobroma cacao seeds, roasted and ground.

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Clostridium

Clostridium is a genus of Gram-positive bacteria, which includes several significant human pathogens, including the causative agent of botulism and an important cause of diarrhea, Clostridium difficile.

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Concentration

In chemistry, concentration is the abundance of a constituent divided by the total volume of a mixture.

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CYP2A6

Cytochrome P450 2A6 (abbreviated CYP2A6) is a member of the cytochrome P450 mixed-function oxidase system, which is involved in the metabolism of xenobiotics in the body.

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Decarboxylation

Decarboxylation is a chemical reaction that removes a carboxyl group and releases carbon dioxide (CO2).

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Decongestant

A decongestant, or nasal decongestant, is a type of pharmaceutical drug that is used to relieve nasal congestion in the upper respiratory tract.

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Derivative (chemistry)

In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.

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Dietary supplement

A dietary supplement is a manufactured product intended to supplement the diet when taken by mouth as a pill, capsule, tablet, or liquid.

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Diethyl ether

Diethyl ether, or simply ether, is an organic compound in the ether class with the formula, sometimes abbreviated as (see Pseudoelement symbols).

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Dopamine

Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is an organic chemical of the catecholamine and phenethylamine families that plays several important roles in the brain and body.

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EC50

Half maximal effective concentration (EC50) refers to the concentration of a drug, antibody or toxicant which induces a response halfway between the baseline and maximum after a specified exposure time.

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Empathogen–entactogen

Empathogens or entactogens are a class of psychoactive drugs that produce experiences of emotional communion, oneness, relatedness, emotional openness—that is, empathy or sympathy—as particularly observed and reported for experiences with 3,4- Methylenedioxymethamphetamine (MDMA).

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Endocytosis

Endocytosis is a form of bulk transport in which a cell transports molecules (such as proteins) into the cell (endo- + cytosis) by engulfing them in an energy-using process.

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Endogeny (biology)

Endogenous substances and processes are those that originate from within an organism, tissue, or cell.

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Enterobacteriaceae

The Enterobacteriaceae are a large family of Gram-negative bacteria.

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Enzyme

Enzymes are macromolecular biological catalysts.

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Ephedrine

Ephedrine is a medication and stimulant.

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Escherichia coli

Escherichia coli (also known as E. coli) is a Gram-negative, facultatively anaerobic, rod-shaped, coliform bacterium of the genus Escherichia that is commonly found in the lower intestine of warm-blooded organisms (endotherms).

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Escherichia coli O157:H7

Escherichia coli O157:H7 is a serotype of the bacterial species Escherichia coli and is one of the Shiga toxin–producing types of E. coli.

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Ethanol

Ethanol, also called alcohol, ethyl alcohol, grain alcohol, and drinking alcohol, is a chemical compound, a simple alcohol with the chemical formula.

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Ethyl group

In chemistry, an ethyl group is an alkyl substituent derived from ethane (C2H6).

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Euphoria

Euphoria is an affective state in which a person experiences pleasure or excitement and intense feelings of well-being and happiness.

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Fanetizole

Fanetizole shows immunoregulating activity.

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Fermentation in food processing

Fermentation in food processing is the process of converting carbohydrates to alcohol or organic acids using microorganisms—yeasts or bacteria—under anaerobic conditions.

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Flavin-containing monooxygenase 3

Flavin-containing monooxygenase 3 (FMO3), also known as dimethylaniline monooxygenase 3 and trimethylamine monooxygenase, is a flavoprotein enzyme that in humans is encoded by the FMO3 gene.

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Friedel–Crafts reaction

The Friedel–Crafts reactions are a set of reactions developed by Charles Friedel and James Crafts in 1877 to attach substituents to an aromatic ring.

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Fungus

A fungus (plural: fungi or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms.

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G protein–coupled receptor

G protein–coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses.

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Half-life

Half-life (symbol t1⁄2) is the time required for a quantity to reduce to half its initial value.

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Hallucinogen

A hallucinogen is a psychoactive agent which can cause hallucinations, perceptual anomalies, and other substantial subjective changes in thoughts, emotion, and consciousness.

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Heck reaction

The Heck reaction (also called the Mizoroki-Heck reaction) is the chemical reaction of an unsaturated halide (or triflate) with an alkene in the presence of a base and a palladium catalyst (or palladium nanomaterial-based catalyst) to form a substituted alkene.

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Hormone

A hormone (from the Greek participle “ὁρμῶ”, "to set in motion, urge on") is any member of a class of signaling molecules produced by glands in multicellular organisms that are transported by the circulatory system to target distant organs to regulate physiology and behaviour.

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Hydrochloride

In chemistry, a hydrochloride is an acid salt resulting, or regarded as resulting, from the reaction of hydrochloric acid with an organic base (e.g. an amine).

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Hydrogen

Hydrogen is a chemical element with symbol H and atomic number 1.

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Hydrogen atom

A hydrogen atom is an atom of the chemical element hydrogen.

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Hydrogenation

Hydrogenation – to treat with hydrogen – is a chemical reaction between molecular hydrogen (H2) and another compound or element, usually in the presence of a catalyst such as nickel, palladium or platinum.

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IC50

The half maximal inhibitory concentration (IC50) is a measure of the potency of a substance in inhibiting a specific biological or biochemical function.

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Isomer

An isomer (from Greek ἰσομερής, isomerès; isos.

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Kidney

The kidneys are two bean-shaped organs present in left and right sides of the body in vertebrates.

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Lactobacillus

Lactobacillus is a genus of Gram-positive, facultative anaerobic or microaerophilic, rod-shaped, non-spore-forming bacteria.

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Lithium aluminium hydride

Lithium aluminium hydride, commonly abbreviated to LAH, is an inorganic compound with the chemical formula LiAlH4.

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Locus coeruleus

The locus coeruleus (\-si-ˈrü-lē-əs\, also spelled locus caeruleus or locus ceruleus) is a nucleus in the pons of the brainstem involved with physiological responses to stress and panic.

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MDMA

3,4-Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy (E), is a psychoactive drug used primarily as a recreational drug.

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Methamphetamine

Methamphetamine (contracted from) is a potent central nervous system (CNS) stimulant that is mainly used as a recreational drug and less commonly as a second-line treatment for attention deficit hyperactivity disorder and obesity.

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Methylphenidate

Methylphenidate, sold under various trade names, Ritalin being one of the most commonly known, is a central nervous system (CNS) stimulant of the phenethylamine and piperidine classes that is used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy.

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Microorganism

A microorganism, or microbe, is a microscopic organism, which may exist in its single-celled form or in a colony of cells. The possible existence of unseen microbial life was suspected from ancient times, such as in Jain scriptures from 6th century BC India and the 1st century BC book On Agriculture by Marcus Terentius Varro. Microbiology, the scientific study of microorganisms, began with their observation under the microscope in the 1670s by Antonie van Leeuwenhoek. In the 1850s, Louis Pasteur found that microorganisms caused food spoilage, debunking the theory of spontaneous generation. In the 1880s Robert Koch discovered that microorganisms caused the diseases tuberculosis, cholera and anthrax. Microorganisms include all unicellular organisms and so are extremely diverse. Of the three domains of life identified by Carl Woese, all of the Archaea and Bacteria are microorganisms. These were previously grouped together in the two domain system as Prokaryotes, the other being the eukaryotes. The third domain Eukaryota includes all multicellular organisms and many unicellular protists and protozoans. Some protists are related to animals and some to green plants. Many of the multicellular organisms are microscopic, namely micro-animals, some fungi and some algae, but these are not discussed here. They live in almost every habitat from the poles to the equator, deserts, geysers, rocks and the deep sea. Some are adapted to extremes such as very hot or very cold conditions, others to high pressure and a few such as Deinococcus radiodurans to high radiation environments. Microorganisms also make up the microbiota found in and on all multicellular organisms. A December 2017 report stated that 3.45 billion year old Australian rocks once contained microorganisms, the earliest direct evidence of life on Earth. Microbes are important in human culture and health in many ways, serving to ferment foods, treat sewage, produce fuel, enzymes and other bioactive compounds. They are essential tools in biology as model organisms and have been put to use in biological warfare and bioterrorism. They are a vital component of fertile soils. In the human body microorganisms make up the human microbiota including the essential gut flora. They are the pathogens responsible for many infectious diseases and as such are the target of hygiene measures.

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Monoamine neurotransmitter

Monoamine neurotransmitters are neurotransmitters and neuromodulators that contain one amino group that is connected to an aromatic ring by a two-carbon chain (such as -CH2-CH2-). All monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, tryptophan, and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes.

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Monoamine oxidase

L-Monoamine oxidases (MAO) are a family of enzymes that catalyze the oxidation of monoamines.

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Monoamine oxidase A

Monoamine oxidase A, also known as MAO-A, is an enzyme that in humans is encoded by the MAOA gene.

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Monoamine oxidase B

Monoamine oxidase B, also known as MAOB, is an enzyme that in humans is encoded by the MAOB gene.

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Monoamine oxidase inhibitor

Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B).

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Monoamine releasing agent

A monoamine releasing agent (MRA), or simply monoamine releaser, is a drug that induces the release of a monoamine neurotransmitter from the presynaptic neuron into the synapse, leading to an increase in the extracellular concentrations of the neurotransmitter.

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Mood (psychology)

In psychology, a mood is an emotional state.

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N-Methylphenethylamine

N-Methylphenethylamine (NMPEA) is a naturally occurring trace amine neuromodulator in humans that is derived from the trace amine, phenethylamine (PEA).

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Natural product

A natural product is a chemical compound or substance produced by a living organism—that is, found in nature.

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Neurobiological effects of physical exercise

The are numerous and involve a wide range of interrelated effects on brain structure, brain function, and cognition.

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Neuromodulation

Neuromodulation is the physiological process by which a given neuron uses one or more chemicals to regulate diverse populations of neurons.

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Neurotransmitter

Neurotransmitters are endogenous chemicals that enable neurotransmission.

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Norepinephrine

Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone and neurotransmitter.

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Oral administration

| name.

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Organic compound

In chemistry, an organic compound is generally any chemical compound that contains carbon.

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Organolithium reagent

Organolithium reagents are organometallic compounds that contain carbon – lithium bonds.

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Organozinc compound

Organozinc compounds in organic chemistry contain carbon to zinc chemical bonds.

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Oxazolone

Oxazolone is a chemical compound and functional group, with the molecular formula C3H3NO2.

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Parachuting

Parachuting, or skydiving, is a method of transiting from a high point to Earth with the aid of gravity, involving the control of speed during the descent with the use of a parachute/s.

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Pars compacta

The pars compacta is a portion of the substantia nigra, located in the midbrain.

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Phenelzine

Phenelzine (Nardil, Nardelzine) is a non-selective and irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class which is used as an antidepressant and anxiolytic.

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Phenformin

Phenformin is an antidiabetic drug from the biguanide class.

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Phentermine

Phentermine (contracted from phenyl-tertiary-butylamine), also known as α,α-dimethylphenethylamine, is a psychostimulant drug of the substituted amphetamine chemical class, with pharmacology similar to amphetamine.

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Phenyl group

In organic chemistry, the phenyl group or phenyl ring is a cyclic group of atoms with the formula C6H5.

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Phenylacetaldehyde

Phenylacetaldehyde is an organic compound used in the synthesis of fragrances and polymers.

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Phenylacetic acid

Phenylacetic acid (PAA) (conjugate base phenylacetate), also known by various synonyms, is an organic compound containing a phenyl functional group and a carboxylic acid functional group.

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Phenylalanine

Phenylalanine (symbol Phe or F) is an α-amino acid with the formula.

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Phenylethanolamine N-methyltransferase

Phenylethanolamine N-methyltransferase (PNMT) is an enzyme found primarily in the adrenal medulla that converts norepinephrine (noradrenaline) to epinephrine (adrenaline).

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Physical dependence

Physical dependence is a physical condition caused by chronic use of a tolerance forming drug, in which abrupt or gradual drug withdrawal causes unpleasant physical symptoms.

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PiHKAL

PiHKAL: A Chemical Love Story is a book by Dr.

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Primary-amine oxidase

Primary-amine oxidase, also known as semicarbazide-sensitive amine oxidase (SSAO), is an enzyme with the systematic name primary-amine:oxygen oxidoreductase (deaminating).

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Protein kinase A

In cell biology, protein kinase A (PKANot to be confused with pKa, the symbol for the acid dissociation constant.) is a family of enzymes whose activity is dependent on cellular levels of cyclic AMP (cAMP).

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Protein kinase C

Protein kinase C, commonly abbreviated to PKC (EC 2.7.11.13), is a family of protein kinase enzymes that are involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins, or a member of this family.

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Pseudoephedrine

Pseudoephedrine (PSE) is a sympathomimetic drug of the phenethylamine and amphetamine chemical classes.

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Pseudomonas

Pseudomonas is a genus of Gram-negative, Gammaproteobacteria, belonging to the family Pseudomonadaceae and containing 191 validly described species.

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Psychedelic drug

Psychedelics are a class of drug whose primary action is to trigger psychedelic experiences via serotonin receptor agonism, causing thought and visual/auditory changes, and altered state of consciousness.

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Psychological dependence

Psychological dependence is a form of dependence that involves emotional–motivational withdrawal symptoms (e.g., a state of unease or dissatisfaction, a reduced capacity to experience pleasure, or anxiety) upon cessation of drug use or exposure to a stimulus.

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Raney nickel

Raney nickel, also called spongy nickel, is a fine-grained solid composed mostly of nickel derived from a nickel-aluminium alloy.

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Salt (chemistry)

In chemistry, a salt is an ionic compound that can be formed by the neutralization reaction of an acid and a base.

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Selegiline

Selegiline, also known as L-deprenyl, is a substituted phenethylamine.

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Small intestine

The small intestine or small bowel is the part of the gastrointestinal tract between the stomach and the large intestine, and is where most of the end absorption of food takes place.

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Stimulant

Stimulants (also often referred to as psychostimulants or colloquially as uppers) is an overarching term that covers many drugs including those that increase activity of the central nervous system and the body, drugs that are pleasurable and invigorating, or drugs that have sympathomimetic effects.

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Substituent

In organic chemistry and biochemistry, a substituent is an atom or group of atoms which replaces one or more hydrogen atoms on the parent chain of a hydrocarbon, becoming a moiety of the resultant new molecule.

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Substituted amphetamine

Substituted amphetamines are a class of compounds based upon the amphetamine structure; it includes all derivative compounds which are formed by replacing, or substituting, one or more hydrogen atoms in the amphetamine core structure with substituents.

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Substituted methylenedioxyphenethylamine

Substituted methylenedioxy- phenethylamines (MDxx) are a large chemical class of derivatives of the phenethylamines, which includes many psychoactive drugs that act as entactogens, psychedelics, and/or stimulants, as well as entheogens.

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Substituted phenethylamine

Substituted phenethylamines (or simply phenethylamines) are a chemical class of organic compounds that are based upon the phenethylamine structure; the class is composed of all the derivative compounds of phenethylamine which can be formed by replacing, or substituting, one or more hydrogen atoms in the phenethylamine core structure with substituents.

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Substitution reaction

Substitution reaction (also known as single displacement reaction or single substitution reaction) is a chemical reaction during which one functional group in a chemical compound is replaced by another functional group.

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Suzuki reaction

The Suzuki reaction is an organic reaction, classified as a coupling reaction, where the coupling partners are a boronic acid and an organohalide catalyzed by a palladium(0) complex.

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TAAR1

Trace amine-associated receptor 1 (TAAR1) is a trace amine-associated receptor (TAAR) protein that in humans is encoded by the TAAR1 gene.

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TAAR2

Trace amine-associated receptor 2 (TAAR2), formerly known as G protein-coupled receptor 58 (GPR58), is a protein that in humans is encoded by the TAAR2 gene.

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Therapeutic effect

Therapeutic effect refers to the responses(s) after a treatment of any kind, the results of which are judged to be desirable and beneficial.

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Trace amine

Trace amines are an endogenous group of trace amine-associated receptor 1 (TAAR1) agonists – and hence, monoaminergic neuromodulators – that are structurally and metabolically related to classical monoamine neurotransmitters.

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Trace amine-associated receptor

Trace amine-associated receptors (TAARs), sometimes referred to as trace amine receptors (TAs or TARs), are a class of G protein-coupled receptors that were discovered in 2001.

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Tyramine

Tyramine (also spelled tyramin), also known by several other names is a naturally occurring trace amine derived from the amino acid tyrosine.

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Tyrosine

Tyrosine (symbol Tyr or Y) or 4-hydroxyphenylalanine is one of the 20 standard amino acids that are used by cells to synthesize proteins.

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Ventral tegmental area

The ventral tegmental area (VTA) (tegmentum is Latin for covering), also known as the ventral tegmental area of Tsai, or simply ventral tegmentum, is a group of neurons located close to the midline on the floor of the midbrain.

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Vesicular monoamine transporter 2

The vesicular monoamine transporter 2 (VMAT2) also known as solute carrier family 18 member 2 (SLC18A2) is a protein that in humans is encoded by the SLC18A2 gene.

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Weight loss

Weight loss, in the context of medicine, health, or physical fitness, refers to a reduction of the total body mass, due to a mean loss of fluid, body fat or adipose tissue or lean mass, namely bone mineral deposits, muscle, tendon, and other connective tissue.

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2,5-Dimethoxy-4-methylamphetamine

2,5-Dimethoxy-4-methylamphetamine (DOM; known on the street as STP, standing for "Serenity, Tranquility and Peace") is a psychedelic and a substituted amphetamine.

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3,4-Methylenedioxyamphetamine

3,4-Methylenedioxyamphetamine (MDA), is an empathogen-entactogen, psychostimulant, and psychedelic drug of the amphetamine family that is encountered mainly as a recreational drug.

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Redirects here:

2-Phenethylamine, 2-Phenylethylamine, 2-phenethylamine, 2-phenyl-1-aminoethane, 2-phenylethanamine, 2-phenylethylamin, 2-phenylethylamine, 64 04 0, B-phenethylamine, B-phenylethylamine, Beta-phenyethylamine, Beta-phenylethylamine, Phenyl-ethyl-amine, Phenylethalymine, Phenylethylamine, Phenylethylamines, Phenylpropylamine, Β-Phenethylamine, Β-Phenylethylamine, Β-aminoethylamine, Β-phenethylamine, Β-phenylethylamine, Βeta-Phenethylamine, Βeta-Phenylethylamine, Βeta-phenethylamine, Βeta-phenylethylamine.

References

[1] https://en.wikipedia.org/wiki/Phenethylamine

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