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Phenylpiperazine

Index Phenylpiperazine

1-Phenylpiperazine is a simple chemical compound featuring a phenyl group bound to a piperazine ring. [1]

75 relations: Acaprazine, Antrafenine, Aripiprazole, Batoprazine, Benzylpiperazine, Bifeprunox, Brexpiprazole, BRL-15,572, Cariprazine, Chemical compound, Ciprofloxacin, CSP-2503, Dapiprazole, Derivative (chemistry), Dimethylphenylpiperazinium, Diphenylmethylpiperazine, Dropropizine, Drug, EGIS-12,233, Elopiprazole, Eltoprazine, Enciprazine, Enpiprazole, Ensaculin, Etoperidone, Flesinoxan, Flibanserin, Fluprazine, Functional group, Itraconazole, Ketoconazole, Levodropropizine, Lorpiprazole, Lubazodone, Mepiprazole, Meta-Chlorophenylpiperazine, Mianserin, Naftopidil, Naluzotan, Naphthylpiperazine, Nefazodone, Niaprazine, Oxypertine, Para-Chlorophenylpiperazine, Para-Fluorophenylpiperazine, Para-Methoxyphenylpiperazine, Pardoprunox, Phenyl group, Piperazine, Posaconazole, ..., Pyridinylpiperazine, Pyrimidinylpiperazine, S-14,506, S-14671, S-15535, SB-258585, SB-271046, SB-357134, SB-399885, Serotonin antagonist and reuptake inhibitor, Sonepiprazole, Substituted piperazine, Tolpiprazole, Trazodone, Trifluoromethylphenylpiperazine, Umespirone, Urapidil, Vesnarinone, Vilazodone, Vortioxetine, WAY-100135, WAY-100635, Zolertine, 1-(2-Diphenyl)piperazine, 2,3-Dichlorophenylpiperazine. Expand index (25 more) »

Acaprazine

Acaprazine (INN) is an anxiolytic and "adrenolytic" drug of the phenylpiperazine group that was never marketed.

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Antrafenine

Antrafenine (Stakane) is a phenylpiperazine derivative drug invented in 1979.

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Aripiprazole

Aripiprazole, sold under the brand name Abilify among others, is an atypical antipsychotic. It is recommended and primarily used in the treatment of schizophrenia and bipolar disorder. Other uses include as an add-on treatment in major depressive disorder, tic disorders, and irritability associated with autism. According to a Cochrane review, evidence for the oral form in schizophrenia is not sufficient to determine effects on general functioning. Additionally, because many people dropped out of the medication trials before they were completed, the overall strength of the conclusions is low. Side effects include neuroleptic malignant syndrome, a movement disorder known as tardive dyskinesia, and high blood sugar in those with diabetes. In the elderly there is an increased risk of death. It is thus not recommended for use in those with psychosis due to dementia. It is pregnancy category C in the United States and category C in Australia, meaning there is possible evidence of harm to the fetus. It is not recommended for women who are breastfeeding. It is unclear whether it is safe or effective in people less than 18 years old. It is a partial dopamine agonist. Aripiprazole was developed by Otsuka in Japan. In the United States, Otsuka America markets it jointly with Bristol-Myers Squibb. From April 2013 to March 2014, sales of Abilify amounted to almost $6.9 billion.

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Batoprazine

Batoprazine is a drug of the phenylpiperazine class which has been described as a serenic or antiaggressive agent.

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Benzylpiperazine

Benzylpiperazine (BZP) is a recreational drug with euphoriant and stimulant properties. The effects produced by BZP are comparable to those produced by amphetamine. Adverse effects have been reported following its use including acute psychosis, renal toxicity and seizures. No deaths have been reported following a sole ingestion of BZP, although there have been at least two deaths from the combination of BZP and MDMA. Its sale is banned in several countries, including Australia, Canada, New Zealand, the United States, the Republic of Ireland, the United Kingdom, Bulgaria, Romania and other parts of Europe.

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Bifeprunox

Bifeprunox (INN) (code name DU-127,090) is an atypical antipsychotic which, similarly to aripiprazole, combines minimal D2 receptor agonism with serotonin receptor agonism.

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Brexpiprazole

Brexpiprazole, sold under the brand name Rexulti, is an atypical antipsychotic.

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BRL-15,572

BRL-15,572 is a drug which acts as a selective antagonist for the serotonin receptor subtype 5-HT1D, with around 60x selectivity over other related receptors.

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Cariprazine

Cariprazine, sold under the brand names Vraylar in the United States and Reagila in Europe, is an atypical antipsychotic which is used in the treatment of schizophrenia and bipolar mania.

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Chemical compound

A chemical compound is a chemical substance composed of many identical molecules (or molecular entities) composed of atoms from more than one element held together by chemical bonds.

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Ciprofloxacin

Ciprofloxacin is an antibiotic used to treat a number of bacterial infections.

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CSP-2503

CSP-2503 is a potent and selective 5-HT1A receptor agonist, 5-HT2A receptor antagonist, and 5-HT3 receptor antagonist of the phenylpiperazine class.

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Dapiprazole

Dapiprazole (Rev-Eyes) is an alpha blocker.

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Derivative (chemistry)

In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.

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Dimethylphenylpiperazinium

Dimethylphenylpiperazinium (DMPP) is a nicotinic acetylcholine receptor agonist which is selective for the ganglionic subtype.

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Diphenylmethylpiperazine

1-(Diphenylmethyl)piperazine, also known as benzhydrylpiperazine, is a chemical compound and piperazine derivative.

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Dropropizine

Dropropizine (or dipropizine) is a cough suppressant.

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Drug

A drug is any substance (other than food that provides nutritional support) that, when inhaled, injected, smoked, consumed, absorbed via a patch on the skin, or dissolved under the tongue causes a temporary physiological (and often psychological) change in the body.

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EGIS-12,233

EGIS-12,233 is a drug with applications in scientific research, acting as a potent and selective antagonist for both the 5-HT6 and 5-HT7 serotonin receptor subtypes, with good selectivity over other receptors.

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Elopiprazole

Elopiprazole is an antipsychotic drug of the phenylpiperazine class which was never marketed.

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Eltoprazine

Eltoprazine (DU-28,853) is a drug of the phenylpiperazine class which is a serenic or antiaggressive agent.

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Enciprazine

Enciprazine (INN, BAN; enciprazine hydrochloride (USAN); developmental code names WY-48624, D-3112), is an anxiolytic and antipsychotic of the phenylpiperazine class which was never marketed.

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Enpiprazole

Enpiprazole (INN, BAN) is an anxiolytic drug of the phenylpiperazine group that was never marketed.

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Ensaculin

Ensaculin (KA-672) is a drug from the coumarin family, which has been researched as a potential treatment for dementia.

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Etoperidone

Etoperidone, associated with several brand names, is an atypical antidepressant which was developed in the 1970s and either is no longer marketed or was never marketed.

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Flesinoxan

Flesinoxan (DU-29,373) is a potent and selective 5-HT1A receptor partial/near-full agonist of the phenylpiperazine class.

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Flibanserin

Flibanserin, sold under the trade name Addyi, is a medication approved for the treatment of pre-menopausal women with hypoactive sexual desire disorder (HSDD).

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Fluprazine

Fluprazine (DU-27,716) is a drug of the phenylpiperazine class.

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Functional group

In organic chemistry, functional groups are specific substituents or moieties within molecules that are responsible for the characteristic chemical reactions of those molecules.

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Itraconazole

Itraconazole is an antifungal medication used to treat a number of fungal infections.

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Ketoconazole

Ketoconazole is a synthetic imidazole antifungal drug used primarily to treat fungal infections.

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Levodropropizine

Levodropropizine is a cough suppressant.

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Lorpiprazole

Lorpiprazole (INN) (brand name Normarex) is a marketed anxiolytic drug of the phenylpiperazine group.

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Lubazodone

Lubazodone (developmental code names YM-992, YM-35995) is an experimental antidepressant which was under development by Yamanouchi for the treatment for major depressive disorder in the late 1990s and early 2000s but was never marketed.

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Mepiprazole

Mepiprazole (INN, BAN) (brand name Psigodal) is an anxiolytic drug of the phenylpiperazine group with additional antidepressant properties that is marketed in Spain.

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Meta-Chlorophenylpiperazine

meta-Chlorophenylpiperazine (mCPP) is a psychoactive drug of the phenylpiperazine class.

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Mianserin

Mianserin, sold under the brand name Tolvon among others, is an atypical antidepressant which is used in the treatment of depression in Europe and elsewhere in the world.

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Naftopidil

Naftopidil (INN, marketed under the brand name Flivas) is a drug used in benign prostatic hypertrophy which acts as a selective α1-adrenergic receptor antagonist or alpha blocker.

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Naluzotan

Naluzotan (INN, USAN; PRX-00023) is a serotonergic drug of the phenylpiperazine class that was under investigation by EPIX Pharmaceuticals Inc for the treatment of generalized anxiety disorder and major depressive disorder.

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Naphthylpiperazine

1-(1-Naphthyl)piperazine (1-NP) is a drug which is a phenylpiperazine derivative.

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Nefazodone

Nefazodone, sold formerly under the brand names Serzone, Dutonin, and Nefadar among others, is an atypical antidepressant which was first marketed by Bristol-Myers Squibb in 1994 but has since largely been discontinued.

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Niaprazine

Niaprazine (INN) (brand name Nopron) is a sedative-hypnotic drug of the phenylpiperazine group.

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Oxypertine

Oxypertine (Equipertine, Forit, Integrin, Lanturil, Lotawin, Opertil) is an antipsychotic used in the treatment of schizophrenia.

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Para-Chlorophenylpiperazine

para-Chlorophenylpiperazine (pCPP) is a psychoactive drug of the phenylpiperazine class.

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Para-Fluorophenylpiperazine

para-Fluorophenylpiperazine (pFPP, 4-FPP, 4-Fluorophenylpiperazine; Fluoperazine, Flipiperazine) is a piperazine derivative with mildly psychedelic and euphoriant effects.

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Para-Methoxyphenylpiperazine

para-Methoxyphenylpiperazine (MeOPP, pMPP, 4-MPP; Paraperazine) is a piperazine derivative with stimulant effects which has been sold as an ingredient in "Party pills", initially in New Zealand and subsequently in other countries around the world.

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Pardoprunox

Pardoprunox (INN) (code name SLV-308) is an antiparkinsonian drug developed by Solvay for the treatment of Parkinson's disease that reached phase III clinical trials before being discontinued.

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Phenyl group

In organic chemistry, the phenyl group or phenyl ring is a cyclic group of atoms with the formula C6H5.

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Piperazine

Piperazine is an organic compound that consists of a six-membered ring containing two nitrogen atoms at opposite positions in the ring.

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Posaconazole

Posaconazole (trade name Noxafil, Posanol) is a triazole antifungal drug.

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Pyridinylpiperazine

1-(2-Pyridinyl)piperazine is a chemical compound and piperazine derivative.

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Pyrimidinylpiperazine

1-(2-Pyrimidinyl)piperazine (1-PP, 1-PmP) is a chemical compound and piperazine derivative.

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S-14,506

S-14,506 is a phenylpiperazine, a 5-HT1A receptor agonist, and a dopamine receptor antagonist.

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S-14671

S-14671 is a naphthylpiperazine derivative which acts as a 5-HT1A receptor agonist (pKi.

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S-15535

S-15535 is a phenylpiperazine drug which is a potent and highly selective 5-HT1A receptor ligand that acts as an agonist and antagonist (weak partial agonist) at the presynaptic and postsynaptic 5-HT1A receptors, respectively.

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SB-258585

SB-258585 is a drug which is used in scientific research.

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SB-271046

SB-271046 is a drug which is used in scientific research.

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SB-357134

SB-357134 is a drug which is used in scientific research.

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SB-399885

SB-399885 is a drug which is used in scientific research.

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Serotonin antagonist and reuptake inhibitor

Serotonin antagonist and reuptake inhibitors (SARIs) are a class of drugs used mainly as antidepressants, but also as anxiolytics and hypnotics.

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Sonepiprazole

Sonepiprazole (U-101,387, PNU-101,387-G) is a drug of the phenylpiperazine class which acts as a highly selective D4 receptor antagonist.

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Substituted piperazine

Substituted piperazines are a class of chemical compounds.

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Tolpiprazole

Tolpiprazole (INN, BAN) (developmental code name H-4170) is an anxiolytic drug of the phenylpiperazine group that was never marketed.

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Trazodone

Trazodone, sold under many brand names worldwide, Page accessed Feb 10, 2016 is an antidepressant medication.

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Trifluoromethylphenylpiperazine

3-Trifluoromethylphenylpiperazine (TFMPP) is a recreational drug of the piperazine chemical class.

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Umespirone

Umespirone (KC-9172) is a drug of the azapirone class which possesses anxiolytic and antipsychotic properties.

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Urapidil

Urapidil is a sympatholytic antihypertensive drug.

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Vesnarinone

Vesnarinone (INN) is a cardiotonic agent.

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Vilazodone

Vilazodone (United States trade name Viibryd) is a serotonergic antidepressant developed by Merck KGaA and licensed by Clinical Data, a biotech company purchased by Forest Laboratories in 2011.

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Vortioxetine

Vortioxetine is an antidepressant medication that is prescribed to treat depression.

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WAY-100135

WAY-100135 is a serotonergic drug of the phenylpiperazine family which is used in scientific research.

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WAY-100635

WAY-100635 is a piperazine drug and research chemical widely used in scientific studies.

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Zolertine

Zolertine is an alpha-adrenoceptor antagonist.

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1-(2-Diphenyl)piperazine

1-(2-Diphenyl)piperazine, also known as RA-7, is a drug which acts as a potent and selective agonist at the 5HT7 serotonin receptor.

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2,3-Dichlorophenylpiperazine

2,3-Dichlorophenylpiperazine (2,3-DCPP or DCPP) is a chemical compound.

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Redirects here:

1-Phenylpiperazine, 1-phenylpiperazine.

References

[1] https://en.wikipedia.org/wiki/Phenylpiperazine

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