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Index Piebaldism

Piebaldism is a rare autosomal dominant disorder of melanocyte development. [1]

28 relations: Albinism, Amelanism, CD117, Cutaneous condition, Demographics of Africa, Dyschromia, Erythrism, Forelock, George Catlin, Heterochromia iridum, Hirschsprung's disease, Leucism, Mandan, Melanism, Melanocyte, Mendelian inheritance, Native Americans in the United States, Neurocristopathy, PAX3, Piebald, Poliosis, Skewbald, SNAI2, The International League of Dermatological Societies, Under the Same Sun, Vitiligo, Waardenburg syndrome, Xanthochromism.


Albinism in humans is a congenital disorder characterized by the complete or partial absence of pigment in the skin, hair and eyes.

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Amelanism (also known as amelanosis) is a pigmentation abnormality characterized by the lack of pigments called melanins, commonly associated with a genetic loss of tyrosinase function.

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Mast/stem cell growth factor receptor (SCFR), also known as proto-oncogene c-Kit or tyrosine-protein kinase Kit or CD117, is a receptor tyrosine kinase protein that in humans is encoded by the KIT gene.

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Cutaneous condition

A cutaneous condition is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, hair, nails, and related muscle and glands.

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Demographics of Africa

The population of Africa has grown rapidly over the past century, and consequently shows a large youth bulge, further reinforced by a low life expectancy of below 50 years in some African countries.

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Dyschromia refers to an alteration of the color of the skin or nails.

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Erythrism or erythrochroism refers to an unusuaI reddish pigmentation of an animal's fur, hair, skin, feathers, or eggshells.

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The forelock or foretop is a part of a horse's mane, that grows from the animal's poll and falls forward between the ears and onto the forehead.

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George Catlin

George Catlin (July 26, 1796 – December 23, 1872) was an American painter, author, and traveler, who specialized in portraits of Native Americans in the Old West.

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Heterochromia iridum

Heterochromia is a difference in coloration, usually of the iris but also of hair or skin.

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Hirschsprung's disease

Hirschsprung's disease (HD or HSCR) is a birth defect in which nerves are missing from parts of the intestine.

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Leucism is a condition in which there is partial loss of pigmentation in an animal resulting in white, pale, or patchy coloration of the skin, hair, feathers, scales or cuticle, but not the eyes.

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The Mandan are a Native American tribe of the Great Plains who have lived for centuries primarily in what is now North Dakota.

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Melanism is a development of the dark-colored pigment melanin in the skin or its appendages and is the opposite of albinism.

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Melanocytes are melanin-producing neural crest-derived cells located in the bottom layer (the stratum basale) of the skin's epidermis, the middle layer of the eye (the uvea), the inner ear, vaginal epithelium, meninges, bones, and heart.

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Mendelian inheritance

Mendelian inheritance is a type of biological inheritance that follows the laws originally proposed by Gregor Mendel in 1865 and 1866 and re-discovered in 1900.

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Native Americans in the United States

Native Americans, also known as American Indians, Indians, Indigenous Americans and other terms, are the indigenous peoples of the United States.

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Neurocristopathy is a diverse class of pathologies that may arise from defects in the development of tissues containing cells commonly derived from the embryonic neural crest cell lineage.

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The PAX3 (paired box gene 3) gene encodes a member of the paired box or PAX family of transcription factors.

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A piebald or pied animal is one that has a pattern of pigmented spots on an unpigmented (white) background of hair, feathers or scales.

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Poliosis, also called poliosis circumscripta, is the decrease or absence of melanin (or colour) in head hair, eyebrows, eyelashes or any other hairy area.

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Skewbald is a colour pattern of horses.

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Zinc finger protein SNAI2 is a protein that in humans is encoded by the SNAI2 gene.

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The International League of Dermatological Societies

The International League of Dermatological Societies (ILDS) is a non-governmental organization that works closely with the World Health Organization.

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Under the Same Sun

Under The Same Sun (UTSS) is a Christian charitable organization that promotes the wellbeing of persons with albinism (PWA) via education and advocacy.

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Vitiligo is a long-term skin condition characterized by patches of the skin losing their pigment.

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Waardenburg syndrome

Waardenburg syndrome is a rare genetic disorder most often characterized by varying degrees of deafness, minor defects in structures arising from the neural crest, and pigmentation changes.

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Xanthochromism (also called xanthochroism or xanthism) is an unusually yellow pigmentation in an animal.

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[1] https://en.wikipedia.org/wiki/Piebaldism

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