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Progesterone receptor

Index Progesterone receptor

The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found inside cells. [1]

Table of Contents

  1. 46 relations: Aglepristone, Antiprogestogen, Asoprisnil, Asoprisnil ecamate, C-terminus, Chromosome 11, DNA, DNA-binding domain, Drospirenone, Dydrogesterone, Endogeny (biology), Gene, KLF9, Levonorgestrel, Lilopristone, Lonaprisan, Mammary alveolus, Mammary gland, Medroxyprogesterone acetate, Megestrol acetate, Membrane progesterone receptor, Messenger RNA, Mifepristone, N-terminus, Norethisterone, Nuclear receptor, Nuclear receptor co-repressor 2, Onapristone, Organic compound, Phytoprogestogen, Progesterone, Progesterone receptor A, Progesterone receptor B, Progestogen, Protein dimer, Protein–protein interaction, Puberty, Ribosome, Selective progesterone receptor modulator, TAF3, Telapristone, Toripristone, Transcription (biology), UBE3A, Ulipristal acetate, Vilaprisan.

Aglepristone

Aglepristone (brand name Alizin; former developmental code names RU-46534, RU-534) is a synthetic, steroidal antiprogestogen related to mifepristone which is marketed by Virbac in several European countries for use in veterinary medicine.

See Progesterone receptor and Aglepristone

Antiprogestogen

Antiprogestogens, or antiprogestins, also known as progesterone antagonists or progesterone blockers, are a class of drugs which prevent progestogens like progesterone from mediating their biological effects in the body.

See Progesterone receptor and Antiprogestogen

Asoprisnil

Asoprisnil (INN; developmental code name J-867) is a synthetic, steroidal selective progesterone receptor modulator that was under development by Schering and TAP Pharmaceutical Products for the treatment of uterine fibroids.

See Progesterone receptor and Asoprisnil

Asoprisnil ecamate

Asoprisnil ecamate (INN) (developmental code name J-956) is a synthetic, steroidal selective progesterone receptor modulator (SPRM) which was under development for the treatment of endometriosis, uterine fibroids, and menopausal symptoms but was discontinued.

See Progesterone receptor and Asoprisnil ecamate

C-terminus

The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, carboxy tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH).

See Progesterone receptor and C-terminus

Chromosome 11

Chromosome 11 is one of the 23 pairs of chromosomes in humans. Progesterone receptor and chromosome 11 are genes on human chromosome 11.

See Progesterone receptor and Chromosome 11

DNA

Deoxyribonucleic acid (DNA) is a polymer composed of two polynucleotide chains that coil around each other to form a double helix.

See Progesterone receptor and DNA

DNA-binding domain

A DNA-binding domain (DBD) is an independently folded protein domain that contains at least one structural motif that recognizes double- or single-stranded DNA.

See Progesterone receptor and DNA-binding domain

Drospirenone

Drospirenone is a progestin and antiandrogen medication which is used in birth control pills to prevent pregnancy and in menopausal hormone therapy, among other uses. Progesterone receptor and Drospirenone are progestogens.

See Progesterone receptor and Drospirenone

Dydrogesterone

Dydrogesterone, sold under the brand name Duphaston among others, is a progestin medication which is used for a variety of indications, including threatened or recurrent miscarriage during pregnancy, dysfunctional bleeding, infertility due to luteal insufficiency, dysmenorrhea, endometriosis, secondary amenorrhea, irregular cycles, premenstrual syndrome, and as a component of menopausal hormone therapy. Progesterone receptor and Dydrogesterone are progestogens.

See Progesterone receptor and Dydrogesterone

Endogeny (biology)

Endogenous substances and processes are those that originate from within a living system such as an organism, tissue, or cell.

See Progesterone receptor and Endogeny (biology)

Gene

In biology, the word gene has two meanings.

See Progesterone receptor and Gene

KLF9

Krueppel-like factor 9 is a protein that in humans is encoded by the KLF9 gene. Progesterone receptor and KLF9 are transcription factors.

See Progesterone receptor and KLF9

Levonorgestrel

Levonorgestrel is a hormonal medication which is used in a number of birth control methods. Progesterone receptor and Levonorgestrel are progestogens.

See Progesterone receptor and Levonorgestrel

Lilopristone

Lilopristone (INN) (developmental code names ZK-98734, ZK-734) is a synthetic, steroidal antiprogestogen with additional antiglucocorticoid activity which was developed by Schering and was patented in 1985.

See Progesterone receptor and Lilopristone

Lonaprisan

Lonaprisan (INN, USAN) (developmental code names ZK-230211, BAY 86-5044, ZK-PRA) is a synthetic, steroidal antiprogestogen which was under development by Bayer HealthCare Pharmaceuticals for the treatment of endometriosis, dysmenorrhea, and breast cancer but was discontinued.

See Progesterone receptor and Lonaprisan

Mammary alveolus

A mammary alveolus (alveoli, from Latin, "little cavity") is a small cavity or sac found in the mammary gland.

See Progesterone receptor and Mammary alveolus

Mammary gland

A mammary gland is an exocrine gland in humans and other mammals that produces milk to feed young offspring.

See Progesterone receptor and Mammary gland

Medroxyprogesterone acetate

Medroxyprogesterone acetate (MPA), also known as depot medroxyprogesterone acetate (DMPA) in injectable form and sold under the brand name Depo-Provera among others, is a hormonal medication of the progestin type. Progesterone receptor and medroxyprogesterone acetate are progestogens.

See Progesterone receptor and Medroxyprogesterone acetate

Megestrol acetate

Megestrol acetate (MGA), sold under the brand name Megace among others, is a progestin medication which is used mainly as an appetite stimulant to treat wasting syndromes such as cachexia. Progesterone receptor and Megestrol acetate are progestogens.

See Progesterone receptor and Megestrol acetate

Membrane progesterone receptor

Membrane progesterone receptors (mPRs) are a group of cell surface receptors and membrane steroid receptors belonging to the progestin and adipoQ receptor (PAQR) family which bind the endogenous progestogen and neurosteroid progesterone, as well as the neurosteroid allopregnanolone. Progesterone receptor and membrane progesterone receptor are progestogens.

See Progesterone receptor and Membrane progesterone receptor

Messenger RNA

In molecular biology, messenger ribonucleic acid (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is read by a ribosome in the process of synthesizing a protein.

See Progesterone receptor and Messenger RNA

Mifepristone

Mifepristone, also known as RU-486, is a medication typically used in combination with misoprostol to bring about a medical abortion during pregnancy and manage early miscarriage.

See Progesterone receptor and Mifepristone

N-terminus

The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide, referring to the free amine group (-NH2) located at the end of a polypeptide.

See Progesterone receptor and N-terminus

Norethisterone

Norethisterone, also known as norethindrone and sold under many brand names, is a progestin medication used in birth control pills, menopausal hormone therapy, and for the treatment of gynecological disorders. Progesterone receptor and Norethisterone are progestogens.

See Progesterone receptor and Norethisterone

Nuclear receptor

In the field of molecular biology, nuclear receptors are a class of proteins responsible for sensing steroids, thyroid hormones, vitamins, and certain other molecules.

See Progesterone receptor and Nuclear receptor

Nuclear receptor co-repressor 2

The nuclear receptor co-repressor 2 is a transcriptional coregulatory protein that contains several nuclear receptor-interacting domains.

See Progesterone receptor and Nuclear receptor co-repressor 2

Onapristone

Onapristone (developmental code names ZK-89299, ZK-299) is a synthetic and steroidal antiprogestogen with additional antiglucocorticoid activity which was developed by Schering and described in 1984 but was never marketed.

See Progesterone receptor and Onapristone

Organic compound

Some chemical authorities define an organic compound as a chemical compound that contains a carbon–hydrogen or carbon–carbon bond; others consider an organic compound to be any chemical compound that contains carbon.

See Progesterone receptor and Organic compound

Phytoprogestogen

Phytoprogestogens, also known as phytoprogestins, are phytochemicals (that is, naturally occurring, plant-derived chemicals) with progestogenic effects. Progesterone receptor and Phytoprogestogen are progestogens.

See Progesterone receptor and Phytoprogestogen

Progesterone

Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. Progesterone receptor and Progesterone are progestogens.

See Progesterone receptor and Progesterone

Progesterone receptor A

The progesterone receptor A (PR-A) is one of three known isoforms of the progesterone receptor (PR), the main biological target of the endogenous progestogen sex hormone progesterone. Progesterone receptor and progesterone receptor A are Intracellular receptors, progestogens and transcription factors.

See Progesterone receptor and Progesterone receptor A

Progesterone receptor B

The progesterone receptor B (PR-B) is one of three known isoforms of the progesterone receptor (PR), the main biological target of the endogenous progestogen sex hormone progesterone. Progesterone receptor and progesterone receptor B are Intracellular receptors, progestogens and transcription factors.

See Progesterone receptor and Progesterone receptor B

Progestogen

Progestogens, also sometimes written progestins, progestagens or gestagens, are a class of natural or synthetic steroid hormones that bind to and activate the progesterone receptors (PR). Progesterone receptor and Progestogen are progestogens.

See Progesterone receptor and Progestogen

Protein dimer

In biochemistry, a protein dimer is a macromolecular complex or multimer formed by two protein monomers, or single proteins, which are usually non-covalently bound.

See Progesterone receptor and Protein dimer

Protein–protein interaction

Protein–protein interactions (PPIs) are physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by interactions that include electrostatic forces, hydrogen bonding and the hydrophobic effect.

See Progesterone receptor and Protein–protein interaction

Puberty

Puberty is the process of physical changes through which a child's body matures into an adult body capable of sexual reproduction.

See Progesterone receptor and Puberty

Ribosome

Ribosomes are macromolecular machines, found within all cells, that perform biological protein synthesis (messenger RNA translation).

See Progesterone receptor and Ribosome

Selective progesterone receptor modulator

A selective progesterone receptor modulator (SPRM) is an agent that acts on the progesterone receptor (PR), the biological target of progestogens like progesterone.

See Progesterone receptor and Selective progesterone receptor modulator

TAF3

Transcription initiation factor TFIID subunit 3 is a protein that in humans is encoded by the TAF3 gene.

See Progesterone receptor and TAF3

Telapristone

Telapristone, as telapristone acetate (proposed brand names Proellex, Progenta; former code name CDB-4124), is a synthetic, steroidal selective progesterone receptor modulator (SPRM) related to mifepristone which is under development by Repros Therapeutics for the treatment of breast cancer, endometriosis, and uterine fibroids.

See Progesterone receptor and Telapristone

Toripristone

Toripristone (INN; developmental code name RU-40555) is a synthetic, steroidal antiglucocorticoid as well as antiprogestogen which was never marketed.

See Progesterone receptor and Toripristone

Transcription (biology)

Transcription is the process of copying a segment of DNA into RNA.

See Progesterone receptor and Transcription (biology)

UBE3A

Ubiquitin-protein ligase E3A (UBE3A) also known as E6AP ubiquitin-protein ligase (E6AP) is an enzyme that in humans is encoded by the UBE3A gene.

See Progesterone receptor and UBE3A

Ulipristal acetate

Ulipristal acetate, sold under the brand name Ella among others, is a medication used for emergency contraception (birth control) and uterine fibroids.

See Progesterone receptor and Ulipristal acetate

Vilaprisan

Vilaprisan (developmental code name BAY-1002670) is a synthetic and steroidal selective progesterone receptor modulator (SPRM) which is under development by Bayer HealthCare Pharmaceuticals for the treatment of endometriosis and uterine fibroids.

See Progesterone receptor and Vilaprisan

References

[1] https://en.wikipedia.org/wiki/Progesterone_receptor

Also known as NR3C3, PGR (gene), Progesterone receptors, Progestin receptor, Receptors, progesterone.