Get it on Google Play
New! Download Unionpedia on your Android™ device!
Faster access than browser!


Index Protease

A protease (also called a peptidase or proteinase) is an enzyme that performs proteolysis: protein catabolism by hydrolysis of peptide bonds. [1]

111 relations: Alcohol, Alpha 1-antichymotrypsin, Alpha-1 antitrypsin, Amino acid, Aminopeptidase, Animal, Antithrombin, Antiviral drug, Apoptosis, Archaea, Asparagine, Asparagine peptide lyase, Aspartic acid, Aspartic protease, Ayurveda, Bacteria, Biochemical cascade, C1-inhibitor, Calpain, Carbon, Carboxylic acid, Carboxypeptidase A, Catabolism, Catalysis, Catalytic triad, Cathepsin G, Chymotrypsin, Coagulation, Complement system, Convergent evolution, Covalent bond, Cysteine, Cysteine protease, Denaturation (biochemistry), Digestion, Duodenum, Elastase, Elimination reaction, Endopeptidase, Enzyme, Enzyme catalysis, Enzyme promiscuity, Eukaryote, Exopeptidase, Factor XII, Fibrinolysis, Flour treatment agent, Fungus, Fusion protein, Glutamic acid, ..., Glutamic protease, Hemotoxin, Histidine, HIV/AIDS, Hydrolysis, Inflammation, Intramembrane protease, Kinin–kallikrein system, Laundry detergent, Lipocalin, Lipophilicity, Mast cell, MEROPS, Metalloproteinase, Nitrogen, Norovirus, Ontogeny, PA clan, Paneer, Papain, Pathogenesis, Pepsin, Peptide bond, PH, Photosynthesis, Pit viper, Plant, Plasmin, Plasminogen activator inhibitor-1, Poliomyelitis, Prokaryote, Protease inhibitor (biology), Protease inhibitor (pharmacology), Proteases in angiogenesis, Proteasome, Protein, Protein family, Protein superfamily, Protein tag, Proteolysis, Serine, Serine protease, Serpin, SERPINI1, Snake venom, Streptogrisin A, TEV protease, The Proteolysis Map, Thiol, Threonine, Threonine protease, Thrombin, TopFIND, Trypsin, Trypsin inhibitor, Trypsinogen, Type I hypersensitivity, Virulence factor, Virus, Withania coagulans, Zinc. Expand index (61 more) »


In chemistry, an alcohol is any organic compound in which the hydroxyl functional group (–OH) is bound to a carbon.

New!!: Protease and Alcohol · See more »

Alpha 1-antichymotrypsin

Alpha 1-antichymotrypsin (symbol α1AC, A1AC, or a1ACT) is an alpha globulin glycoprotein that is a member of the serpin superfamily.

New!!: Protease and Alpha 1-antichymotrypsin · See more »

Alpha-1 antitrypsin

Alpha-1-antitrypsin or α1-antitrypsin (A1AT, A1A, or AAT) is a protein belonging to the serpin superfamily.

New!!: Protease and Alpha-1 antitrypsin · See more »

Amino acid

Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.

New!!: Protease and Amino acid · See more »


Aminopeptidases are enzymes that catalyze the cleavage of amino acids from the amino terminus (N-terminus) of proteins or peptides.

New!!: Protease and Aminopeptidase · See more »


Animals are multicellular eukaryotic organisms that form the biological kingdom Animalia.

New!!: Protease and Animal · See more »


Antithrombin (AT) is a small protein molecule that inactivates several enzymes of the coagulation system.

New!!: Protease and Antithrombin · See more »

Antiviral drug

Antiviral drugs are a class of medication used specifically for treating viral infections rather than bacterial ones.

New!!: Protease and Antiviral drug · See more »


Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.

New!!: Protease and Apoptosis · See more »


Archaea (or or) constitute a domain of single-celled microorganisms.

New!!: Protease and Archaea · See more »


Asparagine (symbol Asn or N), is an α-amino acid that is used in the biosynthesis of proteins.

New!!: Protease and Asparagine · See more »

Asparagine peptide lyase

Asparagine peptide lyase are one of the seven groups in which proteases, also termed proteolytic enzymes, peptidases, or proteinases, are classified according to their catalytic residue.

New!!: Protease and Asparagine peptide lyase · See more »

Aspartic acid

Aspartic acid (symbol Asp or D; salts known as aspartates), is an α-amino acid that is used in the biosynthesis of proteins.

New!!: Protease and Aspartic acid · See more »

Aspartic protease

Aspartic proteases are a catalytic type of protease enzymes that use an activated water molecule bound to one or more aspartate residues for catalysis of their peptide substrates.

New!!: Protease and Aspartic protease · See more »


Ayurveda is a system of medicine with historical roots in the Indian subcontinent.

New!!: Protease and Ayurveda · See more »


Bacteria (common noun bacteria, singular bacterium) is a type of biological cell.

New!!: Protease and Bacteria · See more »

Biochemical cascade

A biochemical cascade, also known as a signaling cascade or signaling pathway, is a series of chemical reactions which are initiated by a stimulus (first messenger) acting on a receptor that is transduced to the cell interior through second messengers (which amplify the initial signal) and ultimately to effector molecules, resulting in a cell response to the initial stimulus.

New!!: Protease and Biochemical cascade · See more »


C1-inhibitor (C1-inh, C1 esterase inhibitor) is a protease inhibitor belonging to the serpin superfamily.

New!!: Protease and C1-inhibitor · See more »


A calpain is a protein belonging to the family of calcium-dependent, non-lysosomal cysteine proteases (proteolytic enzymes) expressed ubiquitously in mammals and many other organisms.

New!!: Protease and Calpain · See more »


Carbon (from carbo "coal") is a chemical element with symbol C and atomic number 6.

New!!: Protease and Carbon · See more »

Carboxylic acid

A carboxylic acid is an organic compound that contains a carboxyl group (C(.

New!!: Protease and Carboxylic acid · See more »

Carboxypeptidase A

Carboxypeptidase A usually refers to the pancreatic exopeptidase that hydrolyzes peptide bonds of C-terminal residues with aromatic or aliphatic side-chains.

New!!: Protease and Carboxypeptidase A · See more »


Catabolism (from Greek κάτω kato, "downward" and βάλλειν ballein, "to throw") is the set of metabolic pathways that breaks down molecules into smaller units that are either oxidized to release energy or used in other anabolic reactions.

New!!: Protease and Catabolism · See more »


Catalysis is the increase in the rate of a chemical reaction due to the participation of an additional substance called a catalysthttp://goldbook.iupac.org/C00876.html, which is not consumed in the catalyzed reaction and can continue to act repeatedly.

New!!: Protease and Catalysis · See more »

Catalytic triad

A catalytic triad is a set of three coordinated amino acids that can be found in the active site of some enzymes.

New!!: Protease and Catalytic triad · See more »

Cathepsin G

Cathepsin G is a protein that in humans is encoded by the CTSG gene.

New!!: Protease and Cathepsin G · See more »


Chymotrypsin (chymotrypsins A and B, alpha-chymar ophth, avazyme, chymar, chymotest, enzeon, quimar, quimotrase, alpha-chymar, alpha-chymotrypsin A, alpha-chymotrypsin) is a digestive enzyme component of pancreatic juice acting in the duodenum, where it performs proteolysis, the breakdown of proteins and polypeptides.

New!!: Protease and Chymotrypsin · See more »


Coagulation (also known as clotting) is the process by which blood changes from a liquid to a gel, forming a blood clot.

New!!: Protease and Coagulation · See more »

Complement system

The complement system is a part of the immune system that enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promotes inflammation, and attacks the pathogen's cell membrane.

New!!: Protease and Complement system · See more »

Convergent evolution

Convergent evolution is the independent evolution of similar features in species of different lineages.

New!!: Protease and Convergent evolution · See more »

Covalent bond

A covalent bond, also called a molecular bond, is a chemical bond that involves the sharing of electron pairs between atoms.

New!!: Protease and Covalent bond · See more »


Cysteine (symbol Cys or C) is a semi-essential proteinogenic amino acid with the formula HO2CCH(NH2)CH2SH.

New!!: Protease and Cysteine · See more »

Cysteine protease

Cysteine proteases, also known as thiol proteases, are enzymes that degrade proteins.

New!!: Protease and Cysteine protease · See more »

Denaturation (biochemistry)

Denaturation is a process in which proteins or nucleic acids lose the quaternary structure, tertiary structure, and secondary structure which is present in their native state, by application of some external stress or compound such as a strong acid or base, a concentrated inorganic salt, an organic solvent (e.g., alcohol or chloroform), radiation or heat.

New!!: Protease and Denaturation (biochemistry) · See more »


Digestion is the breakdown of large insoluble food molecules into small water-soluble food molecules so that they can be absorbed into the watery blood plasma.

New!!: Protease and Digestion · See more »


The duodenum is the first section of the small intestine in most higher vertebrates, including mammals, reptiles, and birds.

New!!: Protease and Duodenum · See more »


In molecular biology, elastase is an enzyme from the class of proteases (peptidases) that break down proteins.

New!!: Protease and Elastase · See more »

Elimination reaction

An elimination reaction is a type of organic reaction in which two substituents are removed from a molecule in either a one or two-step mechanism.

New!!: Protease and Elimination reaction · See more »


Endopeptidase or endoproteinase are proteolytic peptidases that break peptide bonds of nonterminal amino acids (i.e. within the molecule), in contrast to exopeptidases, which break peptide bonds from end-pieces of terminal amino acids.

New!!: Protease and Endopeptidase · See more »


Enzymes are macromolecular biological catalysts.

New!!: Protease and Enzyme · See more »

Enzyme catalysis

Enzyme catalysis is the increase in the rate of a chemical reaction by the active site of a protein.

New!!: Protease and Enzyme catalysis · See more »

Enzyme promiscuity

Enzyme promiscuity is the ability of an enzyme to catalyse a fortuitous side reaction in addition to its main reaction.

New!!: Protease and Enzyme promiscuity · See more »


Eukaryotes are organisms whose cells have a nucleus enclosed within membranes, unlike Prokaryotes (Bacteria and other Archaea).

New!!: Protease and Eukaryote · See more »


An exopeptidase is any peptidase that catalyzes the cleavage of the terminal (or the penultimate) peptide bond; the process releases a single amino acid or dipeptide from the peptide chain.

New!!: Protease and Exopeptidase · See more »

Factor XII

Coagulation factor XII, also known as Hageman factor, is a plasma protein.

New!!: Protease and Factor XII · See more »


Fibrinolysis is a process that prevents blood clots from growing and becoming problematic.

New!!: Protease and Fibrinolysis · See more »

Flour treatment agent

Flour treatment agents (also called improving agents, bread improvers, dough conditioners and dough improvers) are food additives combined with flour to improve baking functionality.

New!!: Protease and Flour treatment agent · See more »


A fungus (plural: fungi or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms.

New!!: Protease and Fungus · See more »

Fusion protein

Fusion proteins or chimeric (\kī-ˈmir-ik) proteins (literally, made of parts from different sources) are proteins created through the joining of two or more genes that originally coded for separate proteins.

New!!: Protease and Fusion protein · See more »

Glutamic acid

Glutamic acid (symbol Glu or E) is an α-amino acid with formula.

New!!: Protease and Glutamic acid · See more »

Glutamic protease

Glutamic proteases are a group of proteolytic enzymes containing a glutamic acid residue within the active site.

New!!: Protease and Glutamic protease · See more »


Hemotoxins, haemotoxins or hematotoxins are toxins that destroy red blood cells (that is, cause haemotoxin), disrupt blood clotting, and/or cause organ degeneration and generalized tissue damage.

New!!: Protease and Hemotoxin · See more »


Histidine (symbol His or H) is an α-amino acid that is used in the biosynthesis of proteins.

New!!: Protease and Histidine · See more »


Human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV).

New!!: Protease and HIV/AIDS · See more »


Hydrolysis is a term used for both an electro-chemical process and a biological one.

New!!: Protease and Hydrolysis · See more »


Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.

New!!: Protease and Inflammation · See more »

Intramembrane protease

Intramembrane proteases (IMPs), also known as intramembrane-cleaving proteases (I-CLiPs), are enzymes that have the property of cleaving transmembrane domains of integral membrane proteins.

New!!: Protease and Intramembrane protease · See more »

Kinin–kallikrein system

The kinin–kallikrein system or simply kinin system is a poorly understood hormonal system with limited available research.

New!!: Protease and Kinin–kallikrein system · See more »

Laundry detergent

Laundry detergent, or washing powder, is a type of detergent (cleaning agent) that is added for cleaning laundry.

New!!: Protease and Laundry detergent · See more »


The lipocalins are a family of proteins which transport small hydrophobic molecules such as steroids, bilins, retinoids, and lipids.

New!!: Protease and Lipocalin · See more »


Lipophilicity (from Greek λίπος "fat" and φίλος "friendly"), refers to the ability of a chemical compound to dissolve in fats, oils, lipids, and non-polar solvents such as hexane or toluene.

New!!: Protease and Lipophilicity · See more »

Mast cell

A mast cell (also known as a mastocyte or a labrocyte) is a type of white blood cell.

New!!: Protease and Mast cell · See more »


MEROPS is an on-line database for peptidases (also known as proteases, proteinases and proteolytic enzymes) and their inhibitors.

New!!: Protease and MEROPS · See more »


A metalloproteinase, or metalloprotease, is any protease enzyme whose catalytic mechanism involves a metal.

New!!: Protease and Metalloproteinase · See more »


Nitrogen is a chemical element with symbol N and atomic number 7.

New!!: Protease and Nitrogen · See more »


Norovirus, sometimes referred to as the winter vomiting bug, is the most common cause of gastroenteritis.

New!!: Protease and Norovirus · See more »


Ontogeny (also ontogenesis or morphogenesis) is the origination and development of an organism, usually from the time of fertilization of the egg to the organism's mature form—although the term can be used to refer to the study of the entirety of an organism's lifespan.

New!!: Protease and Ontogeny · See more »

PA clan

The PA clan ('''P'''roteases of mixed nucleophile, superfamily A) is the largest group of proteases with common ancestry as identified by structural homology.

New!!: Protease and PA clan · See more »


Paneer is a fresh cheese common in South Asia, especially in India.

New!!: Protease and Paneer · See more »


Papain, also known as papaya proteinase I, is a cysteine protease enzyme present in papaya (Carica papaya) and mountain papaya (Vasconcellea cundinamarcensis).

New!!: Protease and Papain · See more »


The pathogenesis of a disease is the biological mechanism (or mechanisms) that leads to the diseased state.

New!!: Protease and Pathogenesis · See more »


Pepsin is an endopeptidase that breaks down proteins into smaller peptides (that is, a protease).

New!!: Protease and Pepsin · See more »

Peptide bond

A peptide bond is a covalent chemical bond linking two consecutive amino acid monomers along a peptide or protein chain.

New!!: Protease and Peptide bond · See more »


In chemistry, pH is a logarithmic scale used to specify the acidity or basicity of an aqueous solution.

New!!: Protease and PH · See more »


Photosynthesis is a process used by plants and other organisms to convert light energy into chemical energy that can later be released to fuel the organisms' activities (energy transformation).

New!!: Protease and Photosynthesis · See more »

Pit viper

The Crotalinae, commonly known as pit vipers,Mehrtens JM.

New!!: Protease and Pit viper · See more »


Plants are mainly multicellular, predominantly photosynthetic eukaryotes of the kingdom Plantae.

New!!: Protease and Plant · See more »


Plasmin is an important enzyme present in blood that degrades many blood plasma proteins, including fibrin clots.

New!!: Protease and Plasmin · See more »

Plasminogen activator inhibitor-1

Plasminogen activator inhibitor-1 (PAI-1) also known as endothelial plasminogen activator inhibitor or serpin E1 is a protein that in humans is encoded by the SERPINE1 gene.

New!!: Protease and Plasminogen activator inhibitor-1 · See more »


Poliomyelitis, often called polio or infantile paralysis, is an infectious disease caused by the poliovirus.

New!!: Protease and Poliomyelitis · See more »


A prokaryote is a unicellular organism that lacks a membrane-bound nucleus, mitochondria, or any other membrane-bound organelle.

New!!: Protease and Prokaryote · See more »

Protease inhibitor (biology)

In biology and biochemistry, protease inhibitors are molecules that inhibit the function of proteases (enzymes that aid the breakdown of proteins).

New!!: Protease and Protease inhibitor (biology) · See more »

Protease inhibitor (pharmacology)

Protease inhibitors (PIs) are a class of antiviral drugs that are widely used to treat HIV/AIDS and hepatitis C. Protease inhibitors prevent viral replication by selectively binding to viral proteases (e.g. HIV-1 protease) and blocking proteolytic cleavage of protein precursors that are necessary for the production of infectious viral particles.

New!!: Protease and Protease inhibitor (pharmacology) · See more »

Proteases in angiogenesis

Angiogenesis is the process of forming new blood vessels from existing blood vessels.

New!!: Protease and Proteases in angiogenesis · See more »


Proteasomes are protein complexes which degrade unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds.

New!!: Protease and Proteasome · See more »


Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

New!!: Protease and Protein · See more »

Protein family

A protein family is a group of evolutionarily-related proteins.

New!!: Protease and Protein family · See more »

Protein superfamily

A protein superfamily is the largest grouping (clade) of proteins for which common ancestry can be inferred (see homology).

New!!: Protease and Protein superfamily · See more »

Protein tag

Protein tags are peptide sequences genetically grafted onto a recombinant protein.

New!!: Protease and Protein tag · See more »


Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids.

New!!: Protease and Proteolysis · See more »


Serine (symbol Ser or S) is an ɑ-amino acid that is used in the biosynthesis of proteins.

New!!: Protease and Serine · See more »

Serine protease

Serine proteases (or serine endopeptidases) are enzymes that cleave peptide bonds in proteins, in which serine serves as the nucleophilic amino acid at the (enzyme's) active site.

New!!: Protease and Serine protease · See more »


Serpins are a superfamily of proteins with similar structures that were first identified for their protease inhibition activity and are found in all kingdoms of life.

New!!: Protease and Serpin · See more »


Neuroserpin is a protein that in humans is encoded by the SERPINI1 gene.

New!!: Protease and SERPINI1 · See more »

Snake venom

Snake venom is highly modified saliva containing zootoxins which facilitates the immobilization and digestion of prey, and defense against threats.

New!!: Protease and Snake venom · See more »

Streptogrisin A

Streptogrisin A (Streptomyces griseus protease A, protease A, proteinase A, Streptomyces griseus proteinase A, Streptomyces griseus serine proteinase 3, Streptomyces griseus serine proteinase A) is an enzyme.

New!!: Protease and Streptogrisin A · See more »

TEV protease

TEV protease (Tobacco Etch Virus nuclear-inclusion-a endopeptidase) is a highly sequence-specific cysteine protease from Tobacco Etch Virus (TEV).

New!!: Protease and TEV protease · See more »

The Proteolysis Map

The Proteolysis MAP (PMAP) is an integrated web resource focused on proteases.

New!!: Protease and The Proteolysis Map · See more »


Thiol is an organosulfur compound that contains a carbon-bonded sulfhydryl (R–SH) group (where R represents an alkyl or other organic substituent).

New!!: Protease and Thiol · See more »


Threonine (symbol Thr or T) is an amino acid that is used in the biosynthesis of proteins.

New!!: Protease and Threonine · See more »

Threonine protease

Threonine proteases are a family of proteolytic enzymes harbouring a threonine (Thr) residue within the active site.

New!!: Protease and Threonine protease · See more »


Thrombin (fibrinogenase, thrombase, thrombofort, topical, thrombin-C, tropostasin, activated blood-coagulation factor II, blood-coagulation factor IIa, factor IIa, E thrombin, beta-thrombin, gamma-thrombin) is a serine protease, an enzyme that, in humans, is encoded by the F2 gene.

New!!: Protease and Thrombin · See more »


TopFIND is the Termini oriented protein Function Inferred Database (TopFIND) is an integrated knowledgebase focused on protein termini, their formation by proteases and functional implications.

New!!: Protease and TopFIND · See more »


Trypsin is a serine protease from the PA clan superfamily, found in the digestive system of many vertebrates, where it hydrolyzes proteins.

New!!: Protease and Trypsin · See more »

Trypsin inhibitor

A trypsin inhibitor is a type of serine protease inhibitor that reduces the biological activity of trypsin.

New!!: Protease and Trypsin inhibitor · See more »


Trypsinogen (EC is the precursor form or zymogen of trypsin, a digestive enzyme.

New!!: Protease and Trypsinogen · See more »

Type I hypersensitivity

Type I hypersensitivity (or immediate hypersensitivity) is an allergic reaction provoked by reexposure to a specific type of antigen referred to as an allergen.

New!!: Protease and Type I hypersensitivity · See more »

Virulence factor

Virulence factors are molecules produced by bacteria, viruses, fungi, and protozoa that add to their effectiveness and enable them to achieve the following.

New!!: Protease and Virulence factor · See more »


A virus is a small infectious agent that replicates only inside the living cells of other organisms.

New!!: Protease and Virus · See more »

Withania coagulans

Withania coagulans (Hindi: Paneer phool पनीरफूल, Sanskrit: Rishyagandha) is a plant in the Solanaceae or nightshade family, native to Afghanistan, Pakistan and the Indian subcontinent.

New!!: Protease and Withania coagulans · See more »


Zinc is a chemical element with symbol Zn and atomic number 30.

New!!: Protease and Zinc · See more »

Redirects here:

Acid protease, Acid proteinase, Antiprotease, Basic protease, E1101, Neutral protease, Neutral proteases, Peptidase, Peptidases, Peptide hydrolases, Protease la, Proteases, Proteinase, Proteinases, Proteolytic Enzyme, Proteolytic cleavage, Proteolytic enzyme, Proteolytic enzymes.


[1] https://en.wikipedia.org/wiki/Protease

Hey! We are on Facebook now! »