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Protein isoform

Index Protein isoform

A protein isoform, or "protein variant" is a member of a set of highly similar proteins that originate from a single gene or gene family and are the result of genetic differences. [1]

52 relations: Actin, Affinity chromatography, Affinity electrophoresis, Alpha-1 antitrypsin, Alternative splicing, AMPK, Biosynthesis, Blood proteins, Carbohydrate, Complementary DNA, Creatine kinase, Enzyme, Exon, Expressed sequence tag, Gene isoform, Genomics, Glucuronosyltransferase, Glycan, Glycoprotein, Glycoside hydrolase, Glycosylation, Glycosyltransferase, Haptoglobin, Human Genome Project, Hyaluronan synthase, Intron, Lectin, Ligation (molecular biology), Messenger RNA, Microarray analysis techniques, Mutation, Myocardial infarction, Neural cell adhesion molecule, Nucleoprotein, Oligosaccharide, Orosomucoid, Polymorphism (biology), Polysialic acid, Post-transcriptional modification, Promoter (genetics), Protein, Proteome, Proteomics, RNA polymerase, RNA splicing, RNA-Seq, Sequence homology, Spliceosome, Trans-splicing, Transcription (biology), ..., Transcription factor, Translation (biology). Expand index (2 more) »

Actin

Actin is a family of globular multi-functional proteins that form microfilaments.

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Affinity chromatography

Affinity chromatography is a method of separating biochemical mixtures based on a highly specific interaction between antigen and antibody, enzyme and substrate, receptor and ligand, or protein and nucleic acid.

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Affinity electrophoresis

Affinity electrophoresis is a general name for many analytical methods used in biochemistry and biotechnology.

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Alpha-1 antitrypsin

Alpha-1-antitrypsin or α1-antitrypsin (A1AT, A1A, or AAT) is a protein belonging to the serpin superfamily.

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Alternative splicing

Alternative splicing, or differential splicing, is a regulated process during gene expression that results in a single gene coding for multiple proteins.

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AMPK

AMPK may stand for.

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Biosynthesis

Biosynthesis (also called anabolism) is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms.

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Blood proteins

Blood proteins, also termed plasma proteins, are proteins present in blood plasma.

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Carbohydrate

A carbohydrate is a biomolecule consisting of carbon (C), hydrogen (H) and oxygen (O) atoms, usually with a hydrogen–oxygen atom ratio of 2:1 (as in water); in other words, with the empirical formula (where m may be different from n).

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Complementary DNA

In genetics, complementary DNA (cDNA) is DNA synthesized from a single stranded RNA (e.g., messenger RNA (mRNA) or microRNA) template in a reaction catalyzed by the enzyme reverse transcriptase.

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Creatine kinase

Creatine kinase (CK), also known as creatine phosphokinase (CPK) or phosphocreatine kinase, is an enzyme expressed by various tissues and cell types.

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Enzyme

Enzymes are macromolecular biological catalysts.

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Exon

An exon is any part of a gene that will encode a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing.

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Expressed sequence tag

In genetics, an expressed sequence tag (EST) is a short sub-sequence of a cDNA sequence.

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Gene isoform

Gene isoforms are mRNAs that are produced from the same locus but are different in their transcription start sites (TSSs), protein coding DNA sequences (CDSs) and/or untranslated regions (UTRs), potentially altering gene function.

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Genomics

Genomics is an interdisciplinary field of science focusing on the structure, function, evolution, mapping, and editing of genomes.

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Glucuronosyltransferase

Uridine 5'-diphospho-glucuronosyltransferase (UDP-glucuronosyltransferase, UGT) is a cytosolic glycosyltransferase that catalyzes the transfer of the glucuronic acid component of UDP-glucuronic acid to a small hydrophobic molecule.

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Glycan

The terms glycan and polysaccharide are defined by IUPAC as synonyms meaning "compounds consisting of a large number of monosaccharides linked glycosidically".

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Glycoprotein

Glycoproteins are proteins that contain oligosaccharide chains (glycans) covalently attached to amino acid side-chains.

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Glycoside hydrolase

Glycoside hydrolases (also called glycosidases or glycosyl hydrolases) catalyze the hydrolysis of glycosidic bonds in complex sugars.

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Glycosylation

Glycosylation (see also chemical glycosylation) is the reaction in which a carbohydrate, i.e. a glycosyl donor, is attached to a hydroxyl or other functional group of another molecule (a glycosyl acceptor).

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Glycosyltransferase

Glycosyltransferases (GTFs, Gtfs) are enzymes (EC 2.4) that establish natural glycosidic linkages.

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Haptoglobin

Haptoglobin (abbreviated as Hp) is the protein that in humans is encoded by the HP gene.

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Human Genome Project

The Human Genome Project (HGP) was an international scientific research project with the goal of determining the sequence of nucleotide base pairs that make up human DNA, and of identifying and mapping all of the genes of the human genome from both a physical and a functional standpoint.

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Hyaluronan synthase

Hyaluronan synthases (HAS) are membrane-bound enzymes which use UDP-α-N-acetyl-D-glucosamine and UDP-α-D-glucuronate as substrates to produce the glycosaminoglycan hyaluronan at the cell surface and extrude it through the membrane into the extracellular space.

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Intron

An intron is any nucleotide sequence within a gene that is removed by RNA splicing during maturation of the final RNA product.

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Lectin

Lectins are carbohydrate-binding proteins, macromolecules that are highly specific for sugar moieties of other molecules.

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Ligation (molecular biology)

In molecular biology, ligation is the joining of two nucleic acid fragments through the action of an enzyme.

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Messenger RNA

Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression.

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Microarray analysis techniques

Microarray analysis techniques are used in interpreting the data generated from experiments on DNA, RNA, and protein microarrays, which allow researchers to investigate the expression state of a large number of genes - in many cases, an organism's entire genome - in a single experiment.

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Mutation

In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements.

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Myocardial infarction

Myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops to a part of the heart, causing damage to the heart muscle.

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Neural cell adhesion molecule

Neural cell adhesion molecule (NCAM), also called CD56, is a homophilic binding glycoprotein expressed on the surface of neurons, glia and skeletal muscle.

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Nucleoprotein

Nucleoproteins are any proteins that are structurally associated with nucleic acids, either DNA or RNA.

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Oligosaccharide

An oligosaccharide (from the Greek ὀλίγος olígos, "a few", and σάκχαρ sácchar, "sugar") is a saccharide polymer containing a small number (typically three to ten) of monosaccharides (simple sugars).

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Orosomucoid

Orosomucoid (ORM) or alpha-1-acid glycoprotein (α1AGp, AGP or AAG) is an acute phase (acute phase protein) plasma alpha-globulin glycoprotein and is modulated by two polymorphic genes.

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Polymorphism (biology)

Polymorphism in biology and zoology is the occurrence of two or more clearly different morphs or forms, also referred to as alternative phenotypes, in the population of a species.

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Polysialic acid

Polysialic acid is an unusual posttranslational modification that occurs on neural cell adhesion molecules (NCAM).

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Post-transcriptional modification

Post-transcriptional modification or Co-transcriptional modification is the process in eukaryotic cells where primary transcript RNA is converted into mature RNA.

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Promoter (genetics)

In genetics, a promoter is a region of DNA that initiates transcription of a particular gene.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Proteome

The proteome is the entire set of proteins that is, or can be, expressed by a genome, cell, tissue, or organism at a certain time.

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Proteomics

Proteomics is the large-scale study of proteins.

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RNA polymerase

RNA polymerase (ribonucleic acid polymerase), both abbreviated RNAP or RNApol, official name DNA-directed RNA polymerase, is a member of a family of enzymes that are essential to life: they are found in all organisms (-species) and many viruses.

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RNA splicing

In molecular biology, splicing is the editing of the nascent precursor messenger RNA (pre-mRNA) transcript into a mature messenger RNA (mRNA).

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RNA-Seq

RNA-Seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), uses next-generation sequencing (NGS) to reveal the presence and quantity of RNA in a biological sample at a given moment.

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Sequence homology

Sequence homology is the biological homology between DNA, RNA, or protein sequences, defined in terms of shared ancestry in the evolutionary history of life.

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Spliceosome

A spliceosome is a large and complex molecular machine found primarily within the splicing speckles of the cell nucleus of eukaryotic cells.

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Trans-splicing

Trans-splicing is a special form of RNA processing in eukaryotes where exons from two different primary RNA transcripts are joined end to end and ligated.

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Transcription (biology)

Transcription is the first step of gene expression, in which a particular segment of DNA is copied into RNA (especially mRNA) by the enzyme RNA polymerase.

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Transcription factor

In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.

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Translation (biology)

In molecular biology and genetics, translation is the process in which ribosomes in the cytoplasm or ER synthesize proteins after the process of transcription of DNA to RNA in the cell's nucleus.

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Redirects here:

Glycoform, Isoform, Isoforms, Protein Isoform, Protein isoforms.

References

[1] https://en.wikipedia.org/wiki/Protein_isoform

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