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53 relations: Angiogenesis, Antibody, Atheroma, Atherosclerosis, C-fos-induced growth factor, Cell (biology), Cell cycle, Cell division, Cell membrane, Cytosol, Disease, Embryo, Fibroblast, Fibrosis, Gene, Gene expression, Glycoprotein, Growth factor, Ligand, Mesenchyme, Mitogen, Molecule, Neuroglia, Oligodendrocyte, Oncogene, PDGFA, PDGFB, PDGFC, PDGFD, PDGFRA, PDGFRB, Phosphoinositide 3-kinase, Phosphorylation, Placental growth factor, Platelet-activating factor, Platelet-derived growth factor receptor, Progenitor, Protein dimer, Protein isoform, Receptor (biochemistry), Receptor antagonist, Receptor tyrosine kinase, Recombinant DNA, Signal transduction, Smooth muscle tissue, STAT3, Stromal cell, Ulcer (dermatology), Vascular endothelial growth factor, Vascular endothelial growth factor B, ..., Vascular endothelial growth factor C, Withaferin A, Wortmannin. Expand index (3 more) »
Angiogenesis
Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels.
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Antibody
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses.
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Atheroma
An atheroma is a reversible accumulation of degenerative material in the inner layer of an artery wall.
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Atherosclerosis
Atherosclerosis is a disease in which the inside of an artery narrows due to the build up of plaque.
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C-fos-induced growth factor
C-fos-induced growth factor (FIGF) (or vascular endothelial growth factor D, VEGF-D) is a vascular endothelial growth factor that in humans is encoded by the FIGF gene.
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Cell (biology)
The cell (from Latin cella, meaning "small room") is the basic structural, functional, and biological unit of all known living organisms.
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Cell cycle
The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication of its DNA (DNA replication) to produce two daughter cells.
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Cell division
Cell division is the process by which a parent cell divides into two or more daughter cells.
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Cell membrane
The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates the interior of all cells from the outside environment (the extracellular space).
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Cytosol
The cytosol, also known as intracellular fluid (ICF) or cytoplasmic matrix, is the liquid found inside cells.
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Disease
A disease is any condition which results in the disorder of a structure or function in an organism that is not due to any external injury.
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Embryo
An embryo is an early stage of development of a multicellular diploid eukaryotic organism.
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Fibroblast
A fibroblast is a type of biological cell that synthesizes the extracellular matrix and collagen, the structural framework (stroma) for animal tissues, and plays a critical role in wound healing.
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Fibrosis
Fibrosis is the formation of excess fibrous connective tissue in an organ or tissue in a reparative or reactive process.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Gene expression
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product.
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Glycoprotein
Glycoproteins are proteins that contain oligosaccharide chains (glycans) covalently attached to amino acid side-chains.
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Growth factor
A growth factor is a naturally occurring substance capable of stimulating cellular growth, proliferation, healing, and cellular differentiation.
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Ligand
In coordination chemistry, a ligand is an ion or molecule (functional group) that binds to a central metal atom to form a coordination complex.
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Mesenchyme
Mesenchyme, in vertebrate embryology, is a type of connective tissue found mostly during the development of the embryo.
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Mitogen
A mitogen is a chemical substance that encourages a cell to commence cell division, triggering mitosis.
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Molecule
A molecule is an electrically neutral group of two or more atoms held together by chemical bonds.
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Neuroglia
Neuroglia, also called glial cells or simply glia, are non-neuronal cells in the central nervous system (brain and spinal cord) and the peripheral nervous system.
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Oligodendrocyte
Oligodendrocytes, or oligodendroglia,.
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Oncogene
An oncogene is a gene that has the potential to cause cancer.
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PDGFA
Platelet-derived growth factor subunit A is a protein that in humans is encoded by the PDGFA gene.
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PDGFB
Platelet-derived growth factor subunit B is a protein that in humans is encoded by the PDGFB gene.
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PDGFC
Platelet-derived growth factor C, also known as PDGF-C, is a 345-amino acid protein that in humans is encoded by the PDGFC gene.
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PDGFD
Platelet-derived growth factor D is a protein that in humans is encoded by the PDGFD gene.
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PDGFRA
PDGFRA, i.e. platelet-derived growth factor receptor A, also termed PDGFRα, i.e. platelet-derived growth factor receptor α, is a receptor located on the surface of a wide range of cell types.
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PDGFRB
Beta-type platelet-derived growth factor receptor is a protein that in humans is encoded by the PDGFRB gene.
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Phosphoinositide 3-kinase
Phosphatidylinositol-4,5-bisphosphate 3-kinase (also called phosphatidylinositide 3-kinases, phosphatidylinositol-3-kinases, PI 3-kinases, PI(3)Ks, PI-3Ks or by the HUGO official stem symbol for the gene family, PI3K(s)) are a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer.
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Phosphorylation
In chemistry, phosphorylation of a molecule is the attachment of a phosphoryl group.
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Placental growth factor
Placental growth factor is a protein that in humans is encoded by the PGF gene.
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Platelet-activating factor
Platelet-activating factor, also known as PAF, PAF-acether or AGEPC (acetyl-glyceryl-ether-phosphorylcholine), is a potent phospholipid activator and mediator of many leukocyte functions, platelet aggregation and degranulation, inflammation, and anaphylaxis.
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Platelet-derived growth factor receptor
Platelet-derived growth factor receptors (PDGF-R) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family.
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Progenitor
In genealogy, the progenitor (rarer: primogenitor; Stammvater or Ahnherr) is the – sometimes legendary – founder of a family, line of descent, clan or tribe, noble house or people group.
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Protein dimer
In biochemistry, a protein dimer is a macromolecular complex formed by two protein monomers, or single proteins, which are usually non-covalently bound.
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Protein isoform
A protein isoform, or "protein variant" is a member of a set of highly similar proteins that originate from a single gene or gene family and are the result of genetic differences.
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Receptor (biochemistry)
In biochemistry and pharmacology, a receptor is a protein molecule that receives chemical signals from outside a cell.
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Receptor antagonist
A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.
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Receptor tyrosine kinase
Receptor tyrosine kinases (RTKs) are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones.
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Recombinant DNA
Recombinant DNA (rDNA) molecules are DNA molecules formed by laboratory methods of genetic recombination (such as molecular cloning) to bring together genetic material from multiple sources, creating sequences that would not otherwise be found in the genome.
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Signal transduction
Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular response.
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Smooth muscle tissue
Smooth muscle is an involuntary non-striated muscle.
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STAT3
Signal transducer and activator of transcription 3 (STAT3) is a transcription factor which in humans is encoded by the STAT3 gene.
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Stromal cell
Stromal cells are connective tissue cells of any organ, for example in the uterine mucosa (endometrium), prostate, bone marrow, lymph node and the ovary.
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Ulcer (dermatology)
An ulcer is a sore on the skin or a mucous membrane, accompanied by the disintegration of tissue.
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Vascular endothelial growth factor
Vascular endothelial growth factor (VEGF), originally known as vascular permeability factor (VPF), is a signal protein produced by cells that stimulates the formation of blood vessels.
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Vascular endothelial growth factor B
Vascular endothelial growth factor B also known as VEGF-B is a protein that, in humans, is encoded by the VEGF-B gene.
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Vascular endothelial growth factor C
Vascular endothelial growth factor C (VEGF-C) is a protein that is a member of the platelet-derived growth factor / vascular endothelial growth factor (PDGF/VEGF) family.
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Withaferin A
Withaferin A is a steroidal lactone, derived from Acnistus arborescens, Withania somnifera (Indian Winter cherry or Ashwagandha in Sanskrit) and other members of Solanaceae family.
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Wortmannin
Wortmannin, a steroid metabolite of the fungi Penicillium funiculosum, Talaromyces wortmannii, is a non-specific, covalent inhibitor of phosphoinositide 3-kinases (PI3Ks).
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References
[1] https://en.wikipedia.org/wiki/Platelet-derived_growth_factor
