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14 relations: Cell membrane, Class II PI 3-kinases, Class III PI 3-kinase, EEA1, FYVE domain, Myotubularin, Phosphatase, Phosphatidylinositol, Phosphatidylinositol 3,5-bisphosphate, Phosphoinositide 3-kinase, Phospholipid, PIKFYVE, PX domain, SNX1.
Cell membrane
The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates the interior of all cells from the outside environment (the extracellular space).
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Class II PI 3-kinases
Class II PI 3-kinases are a subgroup of the enzyme family, phosphoinositide 3-kinase that share a common protein domain structure, substrate specificity and method of activation.
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Class III PI 3-kinase
Class III PI 3-kinase is a subgroup of the enzyme family, phosphoinositide 3-kinase that share a common protein domain structure, substrate specificity and method of activation.
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EEA1
The gene EEA1 encodes for the 1400 amino acid protein, Early Endosome Antigen 1.
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FYVE domain
In molecular biology the FYVE zinc finger domain is named after the four cysteine-rich proteins: Fab 1 (yeast orthologue of PIKfyve), YOTB, Vac 1 (vesicle transport protein), and '''E'''EA1, in which it has been found.
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Myotubularin
Myotubularin domain represents a region within eukaryotic myotubularin-related proteins that is sometimes found with the GRAM domain.
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Phosphatase
A phosphatase is an enzyme that uses water to cleave a phosphoric acid monoester into a phosphate ion and an alcohol.
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Phosphatidylinositol
Phosphatidylinositol consists of a family of lipids as illustrated on the right, a class of the phosphatidylglycerides.
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Phosphatidylinositol 3,5-bisphosphate
Phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) is one of the seven phosphoinositides found in eukaryotic cell membranes.
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Phosphoinositide 3-kinase
Phosphatidylinositol-4,5-bisphosphate 3-kinase (also called phosphatidylinositide 3-kinases, phosphatidylinositol-3-kinases, PI 3-kinases, PI(3)Ks, PI-3Ks or by the HUGO official stem symbol for the gene family, PI3K(s)) are a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer.
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Phospholipid
Phospholipids are a class of lipids that are a major component of all cell membranes.
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PIKFYVE
PIKfyve, a FYVE finger-containing phosphoinositide kinase, is an enzyme that in humans is encoded by the PIKFYVE gene.
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PX domain
The PX domain is a phosphoinositide-binding structural domain involved in targeting of proteins to cell membranes.
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SNX1
Sorting nexin-1 is a protein that in humans is encoded by the SNX1 gene.
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Redirects here:
C11H20O16P2, Phosphatidylinositol-3-phosphate, Pi3p, PtdIns(3)P, PtdIns3P, Sn-1-stearoyl-2-arachidonoyl phosphatidylinositol 3-phosphate.
References
[1] https://en.wikipedia.org/wiki/Phosphatidylinositol_3-phosphate
