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PyAOP reagent

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PyAOP ((7-Azabenzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate) is a coupling reagent used in solid phase peptide synthesis. [1]

8 relations: BOP reagent, Coupling reaction, HATU, Hydroxybenzotriazole, Peptide synthesis, PyBOP, Reagent, 1-Hydroxy-7-azabenzotriazole.

BOP reagent

BOP (benzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophosphate) reagent is a reagent commonly used in the synthesis of peptides.

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Coupling reaction

A coupling reaction in organic chemistry is a general term for a variety of reactions where two hydrocarbon fragments are coupled with the aid of a metal catalyst.

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HATU

HATU (1--1H-1,2,3-triazolopyridinium 3-oxid hexafluorophosphate, Hexafluorophosphate Azabenzotriazole Tetramethyl Uronium) is a reagent used in peptide coupling chemistry to generate an active ester from a carboxylic acid.

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Hydroxybenzotriazole

Hydroxybenzotriazole (abbreviated HOBt) is an organic compound that is a derivative of benzotriazole.

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Peptide synthesis

In organic chemistry, peptide synthesis is the production of peptides, compounds where multiple amino acids are linked via amide bonds, also known as peptide bonds.

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PyBOP

PyBOP (benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate) is a peptide coupling reagent used in solid phase peptide synthesis.

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Reagent

A reagent is a substance or compound added to a system to cause a chemical reaction, or added to test if a reaction occurs.

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1-Hydroxy-7-azabenzotriazole

1-Hydroxy-7-azabenzotriazole (HOAt) is a triazole used as a peptide coupling reagent.

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References

[1] https://en.wikipedia.org/wiki/PyAOP_reagent

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