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PyBOP (benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate) is a peptide coupling reagent used in solid phase peptide synthesis. [1]

9 relations: BOP reagent, Coupling reaction, DEPBT, HATU, HBTU, Hexamethylphosphoramide, Lysergic acid, Peptide synthesis, Reagent.

BOP reagent

BOP (benzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophosphate) reagent is a reagent commonly used in the synthesis of peptides.

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Coupling reaction

A coupling reaction in organic chemistry is a general term for a variety of reactions where two hydrocarbon fragments are coupled with the aid of a metal catalyst.

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DEPBT (3-(diethoxyphosphoryloxy)-1,2,3-benzotriazin-4(3H)-one) is a peptide coupling reagent used in peptide synthesis.

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HATU (1--1H-1,2,3-triazolopyridinium 3-oxid hexafluorophosphate, Hexafluorophosphate Azabenzotriazole Tetramethyl Uronium) is a reagent used in peptide coupling chemistry to generate an active ester from a carboxylic acid.

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HBTU (2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate, Hexafluorophosphate Benzotriazole Tetramethyl Uronium) is a coupling reagent used in solid phase peptide synthesis.

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Hexamethylphosphoramide, often abbreviated HMPA, is a phosphoramide (i.e. an amide of phosphoric acid) with the formula This colorless liquid is a useful polar aprotic solvent and additive in organic synthesis.

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Lysergic acid

Lysergic acid, also known as D-lysergic acid and (+)-lysergic acid, is a precursor for a wide range of ergoline alkaloids that are produced by the ergot fungus and found in the seeds of Turbina corymbosa (ololiuhqui), Argyreia nervosa (Hawaiian Baby Woodrose), and Ipomoea tricolor (morning glories, tlitliltzin).

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Peptide synthesis

In organic chemistry, peptide synthesis is the production of peptides, compounds where multiple amino acids are linked via amide bonds, also known as peptide bonds.

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A reagent is a substance or compound added to a system to cause a chemical reaction, or added to test if a reaction occurs.

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Redirects here:

Benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate.


[1] https://en.wikipedia.org/wiki/PyBOP

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