AM-630 (6-Iodopravadoline) is a drug that acts as a potent and selective inverse agonist for the cannabinoid receptor CB2, with a ''K''i of 32.1 nM at CB2 and 165x selectivity over CB1, at which it acted as a weak partial agonist.
AM-679 (part of the AM cannabinoid series) is a drug that acts as a moderately potent agonist for the cannabinoid receptors, with a ''K''i of 13.5 nM at CB1 and 49.5 nM at CB2.
The New Zealand Press Association (NZPA) was a news agency that existed from 1879 to 2011 and provided national and international news to the media of New Zealand.
Pravadoline (WIN 48,098) is an antiinflammatory and analgesic drug with an IC50 of 4.9 µM and a Ki of 2511 nM at CB1, related in structure to nonsteroidal anti-inflammtory drugs (NSAIDs) such as indometacin.
RCS-8, or 1-(2-cyclohexylethyl)-3-(2-methoxyphenylacetyl)indole, is a synthetic cannabinoid also known as SR-18 or BTM-8 that has been found as an ingredient of "herbal" synthetic cannabis blends.
To combat the illicit synthetic cannabinoid industry many jurisdictions have created a system to control these cannabinoids through their general (or Markush) structure as opposed to their specific identity (or "street name").
Synthetic cannabinoids are a class of molecules that bind to cannabinoid receptors in the body–the same receptors that the cannabinoids in cannabis plants, such as THC and CBD–attach to.
The New Zealand Herald is a daily newspaper published in Auckland, New Zealand, owned by New Zealand Media and Entertainment.