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106 relations: Andrew Fire, Animal, Annual Review of Plant Biology, Argonaute, Base pair, Biochemistry, Cell (journal), Cell cycle, Cold Spring Harbor Laboratory, Complementarity (molecular biology), Complementary DNA, Craig Mello, Current Biology, Current Opinion (Elsevier), Cyclin A, Cyclin E, Cytoplasm, DDX20, DDX5, Dicer, Differentiation (journal), Directionality (molecular biology), Drosophila, EIF2C1, EIF2C2, Endogeny (biology), Endonuclease, Enzyme, Eukaryote, Eukaryotic initiation factor, Eukaryotic large ribosomal subunit (60S), Expression vector, Feedback, Five-prime cap, FMR1, FXR1, G1 phase, G2 phase, Gem-associated protein 4, Gene, Gene expression, Gene silencing, Genes & Development, Genome, HeLa, Heterochromatin, Histone methyltransferase, Homo sapiens, Journal of Biological Chemistry, Lac operon, ..., Locus (genetics), Macronucleus, Messenger RNA, MicroRNA, Molecular Cell, MTDH, Nature (journal), Nature Cell Biology, Nature Genetics, Nature Reviews Genetics, Nature Reviews Molecular Cell Biology, Nature Structural & Molecular Biology, Nobel Prize in Physiology or Medicine, Nuclease, Nucleic Acids Research, Nucleoprotein, Nucleotide, P-bodies, Pharmacology & Therapeutics, Plant, Polyadenylation, Polysome, Proceedings of the National Academy of Sciences of the United States of America, Prokaryote, Protein complex, Protein domain, Protozoa, Repressor, Retrovirology (journal), Ribonuclease III, Ribosome, RNA, RNA (journal), RNA Helicase A, RNA interference, RNA-dependent RNA polymerase, RNA-induced transcriptional silencing, S phase, Schneider 2 cells, Science (journal), Small interfering RNA, SND1, Somatic (biology), TARBP2, Tetrahymena, Three prime untranslated region, Transcription (biology), Transfection, Translation, Trypanosoma brucei, Tudor domain, Viral disease, Yeast, 5S ribosomal RNA, 60S ribosomal protein L11, 60S ribosomal protein L5. Expand index (56 more) »
Andrew Fire
Andrew Zachary Fire (born April 27, 1959) is an American biologist and professor of pathology and of genetics at the Stanford University School of Medicine.
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Animal
Animals are multicellular eukaryotic organisms that form the biological kingdom Animalia.
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Annual Review of Plant Biology
Annual Review of Plant Biology is a peer-reviewed scientific journal published by Annual Reviews Inc. It was first published in 1950 as Plant Physiology and Plant Molecular Biology.
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Argonaute
The Argonaute protein family plays a central role in RNA silencing processes, as essential components of the RNA-induced silencing complex (RISC).
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Base pair
A base pair (bp) is a unit consisting of two nucleobases bound to each other by hydrogen bonds.
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Biochemistry
Biochemistry, sometimes called biological chemistry, is the study of chemical processes within and relating to living organisms.
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Cell (journal)
Cell is a peer-reviewed scientific journal publishing research papers across a broad range of disciplines within the life sciences.
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Cell cycle
The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication of its DNA (DNA replication) to produce two daughter cells.
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Cold Spring Harbor Laboratory
Cold Spring Harbor Laboratory (CSHL) is a private, non-profit institution with research programs focusing on cancer, neuroscience, plant genetics, genomics, and quantitative biology.
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Complementarity (molecular biology)
In molecular biology, complementarity describes a relationship between two structures each following the lock-and-key principle.
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Complementary DNA
In genetics, complementary DNA (cDNA) is DNA synthesized from a single stranded RNA (e.g., messenger RNA (mRNA) or microRNA) template in a reaction catalyzed by the enzyme reverse transcriptase.
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Craig Mello
Craig Cameron Mello (born October 18, 1960) is an American biologist and professor of molecular medicine at the University of Massachusetts Medical School in Worcester, Massachusetts.
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Current Biology
Current Biology is a scientific journal that covers all areas of biology, especially molecular biology, cell biology, genetics, neurobiology, ecology and evolutionary biology.
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Current Opinion (Elsevier)
Current Opinion is a collection of review journals on various disciplines of the life sciences published by Elsevier.
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Cyclin A
Cyclin A is a member of the cyclin family, a group of proteins that function in regulating progression through the cell cycle.
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Cyclin E
Cyclin E is a member of the cyclin family.
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Cytoplasm
In cell biology, the cytoplasm is the material within a living cell, excluding the cell nucleus.
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DDX20
Probable ATP-dependent RNA helicase DDX20, also known as DEAD-box helicase 20 and gem-associated protein 3 (GEMIN3), is an enzyme that in humans is encoded by the DDX20 gene.
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DDX5
Probable ATP-dependent RNA helicase DDX5 also known as DEAD box protein 5 or RNA helicase p68 is an enzyme that in humans is encoded by the DDX5 gene.
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Dicer
Dicer, also known as endoribonuclease Dicer or helicase with RNase motif, is an enzyme that in humans is encoded by the DICER1 gene.
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Differentiation (journal)
Differentiation is a peer-reviewed academic journal covering cell differentiation and cell development.
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Directionality (molecular biology)
Directionality, in molecular biology and biochemistry, is the end-to-end chemical orientation of a single strand of nucleic acid.
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Drosophila
Drosophila is a genus of flies, belonging to the family Drosophilidae, whose members are often called "small fruit flies" or (less frequently) pomace flies, vinegar flies, or wine flies, a reference to the characteristic of many species to linger around overripe or rotting fruit.
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EIF2C1
Protein argonaute-1 is a protein that in humans is encoded by the EIF2C1 gene.
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EIF2C2
Protein argonaute-2 is a protein that in humans is encoded by the EIF2C2 gene.
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Endogeny (biology)
Endogenous substances and processes are those that originate from within an organism, tissue, or cell.
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Endonuclease
Endonucleases are enzymes that cleave the phosphodiester bond within a polynucleotide chain.
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Enzyme
Enzymes are macromolecular biological catalysts.
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Eukaryote
Eukaryotes are organisms whose cells have a nucleus enclosed within membranes, unlike Prokaryotes (Bacteria and other Archaea).
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Eukaryotic initiation factor
Eukaryotic initiation factors (eIFs) are proteins or protein complexes involved in the initiation phase of eukaryotic translation.
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Eukaryotic large ribosomal subunit (60S)
Ribosomal particles are denoted according to their sedimentation coefficients in Svedberg units.
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Expression vector
An expression vector, otherwise known as an expression construct, is usually a plasmid or virus designed for gene expression in cells.
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Feedback
Feedback occurs when outputs of a system are routed back as inputs as part of a chain of cause-and-effect that forms a circuit or loop.
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Five-prime cap
In molecular biology, the five-prime cap (5′ cap) is a specially altered nucleotide on the 5′ end of some primary transcripts such as precursor messenger RNA.
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FMR1
FMR1 (fragile X mental retardation 1) is a human gene that codes for a protein called fragile X mental retardation protein, or FMRP.
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FXR1
Fragile X mental retardation syndrome-related protein 1 is a protein that in humans is encoded by the FXR1 gene.
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G1 phase
The g1 phase, or Gap 1 phase, is the first of four phases of the cell cycle that takes place in eukaryotic cell division.
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G2 phase
G2 phase, or Gap 2 phase, is the second subphase of Interphase in the cell cycle directly preceding mitosis.
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Gem-associated protein 4
Gem-associated protein 4 is a protein that in humans is encoded by the GEMIN4 gene.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Gene expression
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product.
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Gene silencing
Gene silencing is the regulation of gene expression in a cell to prevent the expression of a certain gene.
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Genes & Development
Genes & Development is a peer-reviewed scientific journal covering molecular biology, molecular genetics, cell biology, and development.
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Genome
In the fields of molecular biology and genetics, a genome is the genetic material of an organism.
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HeLa
HeLa (also Hela or hela) is a cell type in an immortal cell line used in scientific research.
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Heterochromatin
Heterochromatin is a tightly packed form of DNA or condensed DNA, which comes in multiple varieties.
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Histone methyltransferase
Histone methyltransferases (HMT) are histone-modifying enzymes (e.g., histone-lysine N-methyltransferases and histone-arginine N-methyltransferases), that catalyze the transfer of one, two, or three methyl groups to lysine and arginine residues of histone proteins.
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Homo sapiens
Homo sapiens is the systematic name used in taxonomy (also known as binomial nomenclature) for the only extant human species.
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Journal of Biological Chemistry
The Journal of Biological Chemistry is a weekly peer-reviewed scientific journal that was established in 1905.
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Lac operon
The lac operon (lactose operon) is an operon required for the transport and metabolism of lactose in Escherichia coli and many other enteric bacteria.
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Locus (genetics)
A locus (plural loci) in genetics is a fixed position on a chromosome, like the position of a gene or a marker (genetic marker).
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Macronucleus
A macronucleus (formerly also meganucleus) is the larger type of nucleus in ciliates.
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Messenger RNA
Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression.
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MicroRNA
A microRNA (abbreviated miRNA) is a small non-coding RNA molecule (containing about 22 nucleotides) found in plants, animals and some viruses, that functions in RNA silencing and post-transcriptional regulation of gene expression.
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Molecular Cell
Molecular Cell is a peer-reviewed scientific journal that covers research on cell biology at the molecular level, with an emphasis on new mechanistic insights.
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MTDH
Metadherin, also known as protein LYRIC or astrocyte elevated gene-1 protein (AEG-1) is a protein that in humans is encoded by the MTDH gene.
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Nature (journal)
Nature is a British multidisciplinary scientific journal, first published on 4 November 1869.
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Nature Cell Biology
Nature Cell Biology is a peer-reviewed scientific journal covering research in cell biology published by the Nature Publishing Group.
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Nature Genetics
Nature Genetics is a scientific journal founded as part of the ''Nature'' family of journals in 1992.
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Nature Reviews Genetics
Nature Reviews Genetics is a monthly review journal in genetics and covers the full breadth of modern genetics.
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Nature Reviews Molecular Cell Biology
Nature Reviews Molecular Cell Biology is a peer-reviewed monthly review journal that was established in October 2000 and is published by Nature Publishing Group.
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Nature Structural & Molecular Biology
Nature Structural & Molecular Biology is a monthly peer-reviewed scientific journal publishing research articles, reviews, news, and commentaries in structural and molecular biology, with an emphasis on papers that further a "functional and mechanistic understanding of how molecular components in a biological process work together".
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Nobel Prize in Physiology or Medicine
The Nobel Prize in Physiology or Medicine (Nobelpriset i fysiologi eller medicin), administered by the Nobel Foundation, is awarded once a year for outstanding discoveries in the fields of life sciences and medicine.
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Nuclease
A nuclease (also archaically known as nucleodepolymerase or polynucleotidase) is an enzyme capable of cleaving the phosphodiester bonds between monomers of nucleic acids.
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Nucleic Acids Research
Nucleic Acids Research is an open-access peer-reviewed scientific journal published by Oxford University Press.
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Nucleoprotein
Nucleoproteins are any proteins that are structurally associated with nucleic acids, either DNA or RNA.
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Nucleotide
Nucleotides are organic molecules that serve as the monomer units for forming the nucleic acid polymers deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essential biomolecules within all life-forms on Earth.
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P-bodies
Processing bodies (P-bodies) are distinct foci within the cytoplasm of the eukaryotic cell consisting of many enzymes involved in mRNA turnover.
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Pharmacology & Therapeutics
Pharmacology & Therapeutics is a medical review journal published by Elsevier.
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Plant
Plants are mainly multicellular, predominantly photosynthetic eukaryotes of the kingdom Plantae.
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Polyadenylation
Polyadenylation is the addition of a poly(A) tail to a messenger RNA.
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Polysome
A polyribosome (or polysome) is a complex of an mRNA molecule and two or more ribosomes that act to translate mRNA instructions into polypeptides.
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Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America (PNAS) is the official scientific journal of the National Academy of Sciences, published since 1915.
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Prokaryote
A prokaryote is a unicellular organism that lacks a membrane-bound nucleus, mitochondria, or any other membrane-bound organelle.
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Protein complex
A protein complex or multiprotein complex is a group of two or more associated polypeptide chains.
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Protein domain
A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain.
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Protozoa
Protozoa (also protozoan, plural protozoans) is an informal term for single-celled eukaryotes, either free-living or parasitic, which feed on organic matter such as other microorganisms or organic tissues and debris.
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Repressor
In molecular genetics, a repressor is a DNA- or RNA-binding protein that inhibits the expression of one or more genes by binding to the operator or associated silencers.
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Retrovirology (journal)
Retrovirology is a peer-reviewed open access scientific journal covering basic research on retroviruses.
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Ribonuclease III
Ribonuclease III (RNase III or RNase C)(BRENDA) is a type of ribonuclease that recognizes dsRNA and cleaves it at specific targeted locations to transform them into mature RNAs.
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Ribosome
The ribosome is a complex molecular machine, found within all living cells, that serves as the site of biological protein synthesis (translation).
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RNA
Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation, and expression of genes.
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RNA (journal)
RNA is a monthly peer-reviewed scientific journal that covers research on all aspects of RNA molecules, including their structures, metabolism, functions, and evolution.
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RNA Helicase A
ATP-dependent RNA helicase A (RHA; also known as DHX9, LKP, and NDHI) is an enzyme that in humans is encoded by the DHX9 gene.
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RNA interference
RNA interference (RNAi) is a biological process in which RNA molecules inhibit gene expression or translation, by neutralizing targeted mRNA molecules.
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RNA-dependent RNA polymerase
RNA-dependent RNA polymerase (RdRP), (RDR), or RNA replicase, is an enzyme that catalyzes the replication of RNA from an RNA template.
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RNA-induced transcriptional silencing
RNA-induced transcriptional silencing (RITS) is a form of RNA interference by which short RNA molecules – such as small interfering RNA (siRNA) – trigger the downregulation of transcription of a particular gene or genomic region.
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S phase
S phase (synthesis phase) is the part of the cell cycle in which DNA is replicated, occurring between G1 phase and G2 phase.
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Schneider 2 cells
Schneider 2 cells, usually abbreviated as S2 cells, are one of the most commonly used Drosophila melanogaster cell lines.
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Science (journal)
Science, also widely referred to as Science Magazine, is the peer-reviewed academic journal of the American Association for the Advancement of Science (AAAS) and one of the world's top academic journals.
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Small interfering RNA
Small interfering RNA (siRNA), sometimes known as short interfering RNA or silencing RNA, is a class of double-stranded RNA molecules, 20-25 base pairs in length, similar to miRNA, and operating within the RNA interference (RNAi) pathway.
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SND1
Staphylococcal nuclease domain-containing protein 1 also known as 100 kDa coactivator or Tudor domain-containing protein 11 (TDRD11) is a protein that in humans is encoded by the SND1 gene.
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Somatic (biology)
The term somatic is often used in biology to refer to the cells of the body in contrast to the germ line cells which usually give rise to the gametes (ovum or sperm).
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TARBP2
RISC-loading complex subunit TARBP2 is a protein that in humans is encoded by the TARBP2 gene.
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Tetrahymena
Tetrahymena is a genus of free-living ciliates that can also switch from commensalistic to pathogenic modes of survival.
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Three prime untranslated region
In molecular genetics, the three prime untranslated region (3'-UTR) is the section of messenger RNA (mRNA) that immediately follows the translation termination codon.
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Transcription (biology)
Transcription is the first step of gene expression, in which a particular segment of DNA is copied into RNA (especially mRNA) by the enzyme RNA polymerase.
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Transfection
Transfection is the process of deliberately introducing naked or purified nucleic acids into eukaryotic cells.
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Translation
Translation is the communication of the meaning of a source-language text by means of an equivalent target-language text.
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Trypanosoma brucei
Trypanosoma brucei is a species of parasitic kinetoplastid belonging to the genus Trypanosoma.
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Tudor domain
In molecular biology a tudor domain is a conserved protein structural domain originally identified as a region of 50 amino acids found in the Tudor protein encoded in Drosophila.
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Viral disease
A viral disease (or viral infection) occurs when an organism's body is invaded by pathogenic viruses, and infectious virus particles (virions) attach to and enter susceptible cells.
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Yeast
Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom.
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5S ribosomal RNA
The 5S ribosomal RNA (5S rRNA) is an approximately 120 nucleotide-long ribosomal RNA molecule with a mass of 40 kDa.
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60S ribosomal protein L11
60S ribosomal protein L11 is a protein that in humans is encoded by the RPL11 gene.
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60S ribosomal protein L5
60S ribosomal protein L5 is a protein that in humans is encoded by the RPL5 gene.
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Redirects here:
Guide strand, MiRISC, RNA induced silencing complex, Rna-induced silencing complex.
References
[1] https://en.wikipedia.org/wiki/RNA-induced_silencing_complex
