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109 relations: ADAR, Adenosine, Alpha helix, Alternative splicing, American Society for Microbiology, Amino acid, Beta-actin, Caenorhabditis elegans, Cambridge University Press, Candida albicans, Cell (biology), Cell nucleus, CIRBP, Cleavage and polyadenylation specificity factor, Cold Spring Harbor Laboratory Press, CPEB, Cytoplasm, Cytoskeleton, Dendrite, DNA-binding domain, DNA-binding protein, Drosophila melanogaster, Elsevier, EMBO Reports, Endothelium, Epithelium, Eukaryote, Evolution, Exon, FEBS Letters, FMR1, Fragile X-associated tremor/ataxia syndrome, Gametogenesis, Gene, Genes & Development, Genome, Germline, Heterogeneous ribonucleoprotein particle, HITS-CLIP, Hydrogen bond, Hypothermia, Hypoxia (medical), Infection and Immunity, Inosine, Intron, Lamella (cell biology), Meiosis, Messenger RNA, Metabolism, MicroRNA, ..., Muscle, N-terminus, National Academy of Sciences, Nature Publishing Group, Nature Reviews Molecular Cell Biology, Neurological disorder, Neuron, Non-coding RNA, NOVA1, Nuclear magnetic resonance spectroscopy, Nuclear pore, Nuclear transport, Nucleic acid double helix, Nucleoprotein, Nucleotide, Oogenesis, PLOS, PLOS Biology, PLOS Genetics, PLOS One, Poly(A)-binding protein, Polyadenylation, Polynucleotide adenylyltransferase, Post-transcriptional modification, Post-transcriptional regulation, Precursor mRNA, Proceedings of the National Academy of Sciences of the United States of America, Prophase, Protein, Protein–protein interaction, PUM2, Retinol-binding protein, RNA, RNA editing, RNA interference, RNA polymerase, RNA recognition motif, RNA splicing, RNA-binding protein database, Sex-determination system, Small interfering RNA, Small nuclear RNA, SnRNP, Somatic (biology), Spliceosome, SR protein, Staufen (protein), Structural motif, Subcellular localization, Subcutaneous tissue, Synapse, The Journal of Neuroscience, Three prime untranslated region, Translation (biology), Ultraviolet, WormBook, X-ray crystallography, ZBP1, Zinc finger. Expand index (59 more) »
ADAR
Double-stranded RNA-specific adenosine deaminase is an enzyme that in humans is encoded by the ADAR gene (which stands for adenosine deaminase acting on RNA).
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Adenosine
Adenosine is both a chemical found in many living systems and a medication.
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Alpha helix
The alpha helix (α-helix) is a common motif in the secondary structure of proteins and is a righthand-spiral conformation (i.e. helix) in which every backbone N−H group donates a hydrogen bond to the backbone C.
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Alternative splicing
Alternative splicing, or differential splicing, is a regulated process during gene expression that results in a single gene coding for multiple proteins.
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American Society for Microbiology
The American Society for Microbiology (ASM), originally the Society of American Bacteriologists, is a professional organization for scientists who study viruses, bacteria, fungi, algae, and protozoa as well as other aspects of microbiology.
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Amino acid
Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.
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Beta-actin
Beta-actin (human gene and protein symbol ACTB/ACTB) is one of six different actin isoforms which have been identified in humans.
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Caenorhabditis elegans
Caenorhabditis elegans is a free-living (not parasitic), transparent nematode (roundworm), about 1 mm in length, that lives in temperate soil environments.
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Cambridge University Press
Cambridge University Press (CUP) is the publishing business of the University of Cambridge.
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Candida albicans
Candida albicans is an opportunistic pathogenic yeast that is a common member of the human gut flora.
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Cell (biology)
The cell (from Latin cella, meaning "small room") is the basic structural, functional, and biological unit of all known living organisms.
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Cell nucleus
In cell biology, the nucleus (pl. nuclei; from Latin nucleus or nuculeus, meaning kernel or seed) is a membrane-enclosed organelle found in eukaryotic cells.
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CIRBP
Cold-inducible RNA-binding protein is a protein that in humans is encoded by the CIRBP gene.
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Cleavage and polyadenylation specificity factor
Cleavage and polyadenylation specificity factor (CPSF) is involved in the cleavage of the 3' signaling region from a newly synthesized pre-messenger RNA (pre-mRNA) molecule in the process of gene transcription.
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Cold Spring Harbor Laboratory Press
Cold Spring Harbor Laboratory Press was founded in 1933 to aid in Cold Spring Harbor Laboratory's purpose of furthering the advance and spread of scientific knowledge.
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CPEB
CPEB, or cytoplasmic polyadenylation element binding protein, is a highly conserved RNA-binding protein that promotes the elongation of the polyadenine tail of messenger RNA.
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Cytoplasm
In cell biology, the cytoplasm is the material within a living cell, excluding the cell nucleus.
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Cytoskeleton
A cytoskeleton is present in all cells of all domains of life (archaea, bacteria, eukaryotes).
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Dendrite
Dendrites (from Greek δένδρον déndron, "tree"), also dendrons, are branched protoplasmic extensions of a nerve cell that propagate the electrochemical stimulation received from other neural cells to the cell body, or soma, of the neuron from which the dendrites project.
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DNA-binding domain
A DNA-binding domain (DBD) is an independently folded protein domain that contains at least one structural motif that recognizes double- or single-stranded DNA.
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DNA-binding protein
DNA-binding proteins are proteins that have DNA-binding domains and thus have a specific or general affinity for single- or double-stranded DNA.
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Drosophila melanogaster
Drosophila melanogaster is a species of fly (the taxonomic order Diptera) in the family Drosophilidae.
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Elsevier
Elsevier is an information and analytics company and one of the world's major providers of scientific, technical, and medical information.
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EMBO Reports
EMBO Reports is a peer-reviewed scientific journal covering research related to biology at a molecular level.
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Endothelium
Endothelium refers to cells that line the interior surface of blood vessels and lymphatic vessels, forming an interface between circulating blood or lymph in the lumen and the rest of the vessel wall.
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Epithelium
Epithelium is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue.
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Eukaryote
Eukaryotes are organisms whose cells have a nucleus enclosed within membranes, unlike Prokaryotes (Bacteria and other Archaea).
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Evolution
Evolution is change in the heritable characteristics of biological populations over successive generations.
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Exon
An exon is any part of a gene that will encode a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing.
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FEBS Letters
FEBS Letters is a peer-reviewed scientific journal covering all aspects of molecular biosciences, including molecular biology and biochemistry.
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FMR1
FMR1 (fragile X mental retardation 1) is a human gene that codes for a protein called fragile X mental retardation protein, or FMRP.
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Fragile X-associated tremor/ataxia syndrome
Fragile X-associated tremor/ataxia syndrome (FXTAS) is a late-onset neurodegenerative disorder associated with male premutation carriers of Fragile X syndrome (FXS) over the age of 50.
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Gametogenesis
Gametogenesis is a biological process by which diploid or haploid precursor cells undergo cell division and differentiation to form mature haploid gametes.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Genes & Development
Genes & Development is a peer-reviewed scientific journal covering molecular biology, molecular genetics, cell biology, and development.
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Genome
In the fields of molecular biology and genetics, a genome is the genetic material of an organism.
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Germline
In biology and genetics, the germline in a multicellular organism is the population of its bodily cells that are so differentiated or segregated that in the usual processes of reproduction they may pass on their genetic material to the progeny.
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Heterogeneous ribonucleoprotein particle
Heterogeneous nuclear ribonucleoproteins (hnRNPs) are complexes of RNA and protein present in the cell nucleus during gene transcription and subsequent post-transcriptional modification of the newly synthesized RNA (pre-mRNA).
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HITS-CLIP
High-throughput sequencing of RNA isolated by crosslinking immunoprecipitation (HITS-CLIP, also known as CLIP-Seq) is a genome-wide means of mapping protein–RNA binding sites or RNA modification sites in vivo.
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Hydrogen bond
A hydrogen bond is a partially electrostatic attraction between a hydrogen (H) which is bound to a more electronegative atom such as nitrogen (N), oxygen (O), or fluorine (F), and another adjacent atom bearing a lone pair of electrons.
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Hypothermia
Hypothermia is reduced body temperature that happens when a body dissipates more heat than it absorbs.
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Hypoxia (medical)
Hypoxia is a condition in which the body or a region of the body is deprived of adequate oxygen supply at the tissue level.
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Infection and Immunity
Infection and Immunity is a peer-reviewed medical journal published by the American Society for Microbiology.
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Inosine
Inosine is a nucleoside that is formed when hypoxanthine is attached to a ribose ring (also known as a ribofuranose) via a β-N9-glycosidic bond.
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Intron
An intron is any nucleotide sequence within a gene that is removed by RNA splicing during maturation of the final RNA product.
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Lamella (cell biology)
A lamella (plural: "lamellae") in biology refers to a thin layer, membrane, or plate of tissue.
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Meiosis
Meiosis (from Greek μείωσις, meiosis, which means lessening) is a specialized type of cell division that reduces the chromosome number by half, creating four haploid cells, each genetically distinct from the parent cell that gave rise to them.
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Messenger RNA
Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression.
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Metabolism
Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical transformations within the cells of organisms.
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MicroRNA
A microRNA (abbreviated miRNA) is a small non-coding RNA molecule (containing about 22 nucleotides) found in plants, animals and some viruses, that functions in RNA silencing and post-transcriptional regulation of gene expression.
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Muscle
Muscle is a soft tissue found in most animals.
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N-terminus
The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide referring to the free amine group (-NH2) located at the end of a polypeptide.
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National Academy of Sciences
The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization.
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Nature Publishing Group
Nature Publishing Group is a division of the international scientific publishing company Springer Nature that publishes academic journals, magazines, online databases, and services in science and medicine.
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Nature Reviews Molecular Cell Biology
Nature Reviews Molecular Cell Biology is a peer-reviewed monthly review journal that was established in October 2000 and is published by Nature Publishing Group.
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Neurological disorder
A neurological disorder is any disorder of the nervous system.
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Neuron
A neuron, also known as a neurone (British spelling) and nerve cell, is an electrically excitable cell that receives, processes, and transmits information through electrical and chemical signals.
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Non-coding RNA
A non-coding RNA (ncRNA) is an RNA molecule that is not translated into a protein.
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NOVA1
RNA-binding protein Nova-1 is a protein that in humans is encoded by the NOVA1 gene.
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Nuclear magnetic resonance spectroscopy
Nuclear magnetic resonance spectroscopy, most commonly known as NMR spectroscopy or magnetic resonance spectroscopy (MRS), is a spectroscopic technique to observe local magnetic fields around atomic nuclei.
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Nuclear pore
Nuclear pore complexes are large protein complexes that span the nuclear envelope, which is the double membrane surrounding the eukaryotic cell nucleus.
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Nuclear transport
The entry and exit of large molecules from the cell nucleus is tightly controlled by the nuclear pore complexes (NPCs).
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Nucleic acid double helix
In molecular biology, the term double helix refers to the structure formed by double-stranded molecules of nucleic acids such as DNA.
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Nucleoprotein
Nucleoproteins are any proteins that are structurally associated with nucleic acids, either DNA or RNA.
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Nucleotide
Nucleotides are organic molecules that serve as the monomer units for forming the nucleic acid polymers deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essential biomolecules within all life-forms on Earth.
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Oogenesis
Oogenesis, ovogenesis, or oögenesis is the differentiation of the ovum (egg cell) into a cell competent to further development when fertilized.
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PLOS
PLOS (for Public Library of Science) is a nonprofit open access science, technology and medicine publisher, innovator and advocacy organization with a library of open access journals and other scientific literature under an open content license.
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PLOS Biology
PLOS Biology is a peer-reviewed scientific journal covering all aspects of Biology.
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PLOS Genetics
PLOS Genetics is an open access peer-reviewed genetics-focused journal established in 2005 by the non-profit organization Public Library of Science (PLOS).
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PLOS One
PLOS One (stylized PLOS ONE, and formerly PLoS ONE) is a peer-reviewed open access scientific journal published by the Public Library of Science (PLOS) since 2006.
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Poly(A)-binding protein
Poly(A)-binding protein (PAB or PABP) is a RNA-binding protein which binds to the poly(A) tail of mRNA.
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Polyadenylation
Polyadenylation is the addition of a poly(A) tail to a messenger RNA.
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Polynucleotide adenylyltransferase
In enzymology, a polynucleotide adenylyltransferase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are ATP and RNA, whereas its two products are pyrophosphate and RNA with an extra adenosine nucleotide at its 3' end.
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Post-transcriptional modification
Post-transcriptional modification or Co-transcriptional modification is the process in eukaryotic cells where primary transcript RNA is converted into mature RNA.
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Post-transcriptional regulation
Italic textÀ Post-transcriptional regulation is the control of gene expression at the RNA level, therefore between the transcription and the translation of the gene.
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Precursor mRNA
Precursor mRNA (pre-mRNA) is an immature single strand of messenger ribonucleic acid (mRNA).
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Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America (PNAS) is the official scientific journal of the National Academy of Sciences, published since 1915.
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Prophase
Prophase (from the Greek πρό, "before" and φάσις, "stage") is the first stage of cell division in both mitosis and meiosis.
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Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
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Protein–protein interaction
Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.
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PUM2
Pumilio homolog 2 is an RNA-binding protein that in humans is encoded by the PUM2 gene.
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Retinol-binding protein
Retinol-binding proteins (RBP) are a family of proteins with diverse functions.
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RNA
Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation, and expression of genes.
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RNA editing
RNA editing is a molecular process through which some cells can make discrete changes to specific nucleotide sequences within an RNA molecule after it has been generated by RNA polymerase.
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RNA interference
RNA interference (RNAi) is a biological process in which RNA molecules inhibit gene expression or translation, by neutralizing targeted mRNA molecules.
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RNA polymerase
RNA polymerase (ribonucleic acid polymerase), both abbreviated RNAP or RNApol, official name DNA-directed RNA polymerase, is a member of a family of enzymes that are essential to life: they are found in all organisms (-species) and many viruses.
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RNA recognition motif
RNA recognition motif, RNP-1 is a putative RNA-binding domain of about 90 amino acids that are known to bind single-stranded RNAs.
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RNA splicing
In molecular biology, splicing is the editing of the nascent precursor messenger RNA (pre-mRNA) transcript into a mature messenger RNA (mRNA).
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RNA-binding protein database
The RNA-binding Proteins Database (RBPDB) is a biological database of RNA-binding protein specificities that includes experimental observations of RNA-binding sites.
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Sex-determination system
A sex-determination system is a biological system that determines the development of sexual characteristics in an organism.
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Small interfering RNA
Small interfering RNA (siRNA), sometimes known as short interfering RNA or silencing RNA, is a class of double-stranded RNA molecules, 20-25 base pairs in length, similar to miRNA, and operating within the RNA interference (RNAi) pathway.
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Small nuclear RNA
Small nuclear ribonucleic acid (snRNA), also commonly referred to as U-RNA, is a class of small RNA molecules that are found within the splicing speckles and Cajal bodies of the cell nucleus in eukaryotic cells.
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SnRNP
snRNPs (pronounced "snurps"), or small nuclear ribonucleoproteins, are RNA-protein complexes that combine with unmodified pre-mRNA and various other proteins to form a spliceosome, a large RNA-protein molecular complex upon which splicing of pre-mRNA occurs.
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Somatic (biology)
The term somatic is often used in biology to refer to the cells of the body in contrast to the germ line cells which usually give rise to the gametes (ovum or sperm).
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Spliceosome
A spliceosome is a large and complex molecular machine found primarily within the splicing speckles of the cell nucleus of eukaryotic cells.
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SR protein
SR proteins are a conserved family of proteins involved in RNA splicing.
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Staufen (protein)
Staufen is a protein product of a maternally expressed gene in Drosophila melanogaster that has been implicated in helping regulate genes important in determination of gradients that set up the anterior posterior axis such as bicoid and oskar.
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Structural motif
In a chain-like biological molecule, such as a protein or nucleic acid, a structural motif is a supersecondary structure, which also appears in a variety of other molecules.
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Subcellular localization
The cells of eukaryotic organisms are elaborately subdivided into functionally-distinct membrane-bound compartments.
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Subcutaneous tissue
The subcutaneous tissue, also called the hypodermis, hypoderm, subcutis, or superficial fascia, is the lowermost layer of the integumentary system in vertebrates.
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Synapse
In the nervous system, a synapse is a structure that permits a neuron (or nerve cell) to pass an electrical or chemical signal to another neuron or to the target efferent cell.
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The Journal of Neuroscience
The Journal of Neuroscience is a weekly peer-reviewed scientific journal published by the Society for Neuroscience.
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Three prime untranslated region
In molecular genetics, the three prime untranslated region (3'-UTR) is the section of messenger RNA (mRNA) that immediately follows the translation termination codon.
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Translation (biology)
In molecular biology and genetics, translation is the process in which ribosomes in the cytoplasm or ER synthesize proteins after the process of transcription of DNA to RNA in the cell's nucleus.
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Ultraviolet
Ultraviolet (UV) is electromagnetic radiation with a wavelength from 10 nm to 400 nm, shorter than that of visible light but longer than X-rays.
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WormBook
WormBook is an open access, comprehensive collection of original, peer-reviewed chapters covering topics related to the biology of the nematode worm Caenorhabditis elegans (C. elegans).
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X-ray crystallography
X-ray crystallography is a technique used for determining the atomic and molecular structure of a crystal, in which the crystalline atoms cause a beam of incident X-rays to diffract into many specific directions.
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ZBP1
Z-DNA-binding protein 1, also known as DNA-dependent activator of IFN-regulatory factors (DAI) and DLM-1, is a protein that in humans is encoded by the ZBP1 gene.
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Zinc finger
A zinc finger is a small protein structural motif that is characterized by the coordination of one or more zinc ions (Zn2+) in order to stabilize the fold.
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References
[1] https://en.wikipedia.org/wiki/RNA-binding_protein
