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RRM3 is a gene that encodes a 5′-to-3′ DNA helicase known affect multiple cellular replication and repair processes and is most commonly studied in Saccharomyces cerevisiae. [1]

13 relations: Centromere, DNA replication, G-quadruplex, Helicase, MRX complex, N-terminus, Origin recognition complex, Proliferating cell nuclear antigen, Replication stress, Ribosomal DNA, Saccharomyces cerevisiae, Telomere, Transfer RNA.

Centromere

The centromere is the specialized DNA sequence of a chromosome that links a pair of sister chromatids (a dyad).

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DNA replication

In molecular biology, DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule.

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G-quadruplex

In molecular biology, G-quadruplex secondary structures are formed in nucleic acids by sequences that are rich in guanine.

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Helicase

Helicases are a class of enzymes vital to all living organisms.

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MRX complex

The MRX complex is a heterotrimeric protein complex consisting of Mre11, Rad50, and Xrs2.

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N-terminus

The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide referring to the free amine group (-NH2) located at the end of a polypeptide.

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Origin recognition complex

In molecular biology, origin recognition complex (ORC) is a multi-subunit DNA binding complex (6 subunits) that binds in all eukaryotes in an ATP-dependent manner to origins of replication.

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Proliferating cell nuclear antigen

Proliferating cell nuclear antigen (PCNA) is a DNA clamp that acts as a processivity factor for DNA polymerase δ in eukaryotic cells and is essential for replication.

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Replication stress

Replication stress is defined as the events that take place when the genome is exposed to various stresses.

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Ribosomal DNA

Ribosomal DNA (rDNA) is a DNA sequence that codes for ribosomal RNA.

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Saccharomyces cerevisiae

Saccharomyces cerevisiae is a species of yeast.

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Telomere

A telomere is a region of repetitive nucleotide sequences at each end of a chromosome, which protects the end of the chromosome from deterioration or from fusion with neighboring chromosomes.

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Transfer RNA

A transfer RNA (abbreviated tRNA and formerly referred to as sRNA, for soluble RNA) is an adaptor molecule composed of RNA, typically 76 to 90 nucleotides in length, that serves as the physical link between the mRNA and the amino acid sequence of proteins.

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Redirects here:

Ribosomal DNArecombination mutation 3, Rrm3p.

References

[1] https://en.wikipedia.org/wiki/RRM3

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