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Index RU-16117

RU-16117 is an estrogen medication which was investigated for the potential treatment of symptoms of estrogen deficiency such as hot flashes and osteoporosis in women but was never marketed. [1]

34 relations: Agonist, Aldosterone, Androgen receptor, Antiestrogen, Derivative (chemistry), Epimer, Estradiol (medication), Estrane, Estriol (medication), Estrogen (medication), Estrogen ester, Estrogen receptor, Ethinylestradiol, Glucocorticoid receptor, Hot flash, Hydrocortisone, Hypoestrogenism, Isomer, Ligand (biochemistry), Methoxy group, Mineralocorticoid receptor, Mouse, Moxestrol, Oral administration, Organic compound, Osteoporosis, Partial agonist, Progesterone (medication), Progesterone receptor, Steroid, Symptom, Testosterone (medication), Tissue (biology), Uterus.


An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.

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Aldosterone, the main mineralocorticoid hormone, is a steroid hormone produced by the zona glomerulosa of the adrenal cortex in the adrenal gland.

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Androgen receptor

The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus.

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Antiestrogens, also known as estrogen antagonists or estrogen blockers, are a class of drugs which prevent estrogens like estradiol from mediating their biological effects in the body.

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Derivative (chemistry)

In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.

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In stereochemistry, an epimer is one of a pair of stereoisomers.

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Estradiol (medication)

Estradiol, also spelled oestradiol, is a medication and naturally occurring steroid hormone.

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Estrane is a C18 steroid derivative, with a gonane core.

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Estriol (medication)

Estriol, sold under the brand name Ovestin among others, is an estrogen medication and naturally occurring steroid hormone which is used in menopausal hormone therapy.

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Estrogen (medication)

An estrogen is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.

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Estrogen ester

An estrogen ester is an ester of an estrogen, generally of estradiol but also and alternatively of estrone or estriol.

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Estrogen receptor

Estrogen receptors (ERs) are a group of proteins found inside cells.

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Ethinylestradiol (EE) is an estrogen medication which is used widely in birth control pills in combination with progestins.

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Glucocorticoid receptor

The glucocorticoid receptor (GR, or GCR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1) is the receptor to which cortisol and other glucocorticoids bind.

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Hot flash

Hot flashes (American English) or hot flushes (British English) are a form of flushing due to reduced levels of estradiol.

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Hydrocortisone, sold under a number of brand names, is the name for the hormone cortisol when supplied as a medication.

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Hypoestrogenism, or estrogen deficiency, refers to a lower than normal level of estrogen, the primary sex hormone in women.

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An isomer (from Greek ἰσομερής, isomerès; isos.

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Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.

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Methoxy group

A methoxy group is the functional group consisting of a methyl group bound to oxygen.

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Mineralocorticoid receptor

The mineralocorticoid receptor (or MR, MLR, MCR), also known as the aldosterone receptor or nuclear receptor subfamily 3, group C, member 2, (NR3C2) is a protein that in humans is encoded by the NR3C2 gene that is located on chromosome 4q31.1-31.2.

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A mouse (Mus), plural mice, is a small rodent characteristically having a pointed snout, small rounded ears, a body-length scaly tail and a high breeding rate.

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Moxestrol, sold under the brand name Surestryl, is an estrogen medication which is or was used in Europe for the treatment of menopausal symptoms and menstrual disorders.

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Oral administration

| name.

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Organic compound

In chemistry, an organic compound is generally any chemical compound that contains carbon.

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Osteoporosis is a disease where increased bone weakness increases the risk of a broken bone.

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Partial agonist

In pharmacology, partial agonists are drugs that bind to and activate a given receptor, but have only partial efficacy at the receptor relative to a full agonist.

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Progesterone (medication)

Progesterone is a medication and naturally occurring steroid hormone.

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Progesterone receptor

The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found inside cells.

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A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.

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A symptom (from Greek σύμπτωμα, "accident, misfortune, that which befalls", from συμπίπτω, "I befall", from συν- "together, with" and πίπτω, "I fall") is a departure from normal function or feeling which is noticed by a patient, reflecting the presence of an unusual state, or of a disease.

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Testosterone (medication)

Testosterone is a medication and naturally occurring steroid hormone.

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Tissue (biology)

In biology, tissue is a cellular organizational level between cells and a complete organ.

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The uterus (from Latin "uterus", plural uteri) or womb is a major female hormone-responsive secondary sex organ of the reproductive system in humans and most other mammals.

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Redirects here:

11α-MeO-17α-EE, 11α-MeO-EE, 11α-Methoxy-17α-ethynylestradiol, 11α-Methoxyethinylestradiol, 11α-methoxy-17α-ethynylestradiol, 11α-methoxyethinylestradiol, R 16,117, R 16117, R-16,117, R-16117, R16117, RU 16,117, RU 16117, RU-16,117, RU16117.


[1] https://en.wikipedia.org/wiki/RU-16117

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