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39 relations: Aldosterone, Anabolic steroid, Androgen, Androgen receptor, Androstanolone, Antiandrogen, Antiestrogen, Antimineralocorticoid, Benorterone, Binding selectivity, BOMT, Cyproterone, Cyproterone acetate, Derivative (chemistry), Dihydrotestosterone, Estradiol (medication), Estrane, Estrogen (medication), Flutamide, France, In vitro, Intrinsic activity, Ligand (biochemistry), Metribolone, Nandrolone, Nilutamide, Nonsteroidal antiandrogen, Organic compound, Partial agonist, Potency (pharmacology), Progesterone (medication), Progestogen, Receptor antagonist, Roussel Uclaf, Scientific method, Steroid, Steroidal antiandrogen, Testosterone (medication), Trenbolone.
Aldosterone
Aldosterone, the main mineralocorticoid hormone, is a steroid hormone produced by the zona glomerulosa of the adrenal cortex in the adrenal gland.
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Anabolic steroid
Anabolic steroids, also known more properly as anabolic–androgenic steroids (AAS), are steroidal androgens that include natural androgens like testosterone as well as synthetic androgens that are structurally related and have similar effects to testosterone.
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Androgen
An androgen (from Greek andr-, the stem of the word meaning "man") is any natural or synthetic steroid hormone which regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors.
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Androgen receptor
The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus.
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Androstanolone
Androstanolone, or stanolone, also known as dihydrotestosterone (DHT) and sold under the brand name Andractim among others, is an androgen and anabolic steroid (AAS) medication and hormone which is used mainly in the treatment of low testosterone levels in men.
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Antiandrogen
Antiandrogens, also known as androgen antagonists or testosterone blockers, are a class of drugs that prevent androgens like testosterone and dihydrotestosterone (DHT) from mediating their biological effects in the body.
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Antiestrogen
Antiestrogens, also known as estrogen antagonists or estrogen blockers, are a class of drugs which prevent estrogens like estradiol from mediating their biological effects in the body.
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Antimineralocorticoid
An antimineralocorticoid, MCRA, or an aldosterone antagonist, is a diuretic drug which antagonizes the action of aldosterone at mineralocorticoid receptors.
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Benorterone
Benorterone, also known by its developmental code name SKF-7690 and as 17α-methyl-B-nortestosterone, is an steroidal antiandrogen which was studied for potential medical use but was never marketed.
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Binding selectivity
Binding selectivity is defined with respect to the binding of ligands to a substrate forming a complex.
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BOMT
BOMT, also known by its developmental code name Ro 7-2340 and as 6α-bromo-4-oxa-17α-methyl-5α-dihydrotestosterone, is a synthetic steroidal antiandrogen which was first developed in 1970 and was never marketed for medical use.
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Cyproterone
Cyproterone, also known by its developmental code name SH-80881, is a steroidal antiandrogen which was studied in the 1960s and 1970s but was never introduced for medical use.
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Cyproterone acetate
Cyproterone acetate (CPA), sold alone under the brand name Androcur or with ethinylestradiol (EE) under the brand names Diane or Diane-35 among others, is an antiandrogen and progestogen which is used in the treatment of androgen-dependent conditions like acne, excessive hair growth, early puberty, and prostate cancer, as a component of feminizing hormone therapy for transgender women, and in birth control pills.
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Derivative (chemistry)
In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.
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Dihydrotestosterone
Dihydrotestosterone (DHT), or 5α-dihydrotestosterone (5α-DHT), also known as androstanolone or stanolone, is an endogenous androgen sex steroid and hormone.
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Estradiol (medication)
Estradiol, also spelled oestradiol, is a medication and naturally occurring steroid hormone.
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Estrane
Estrane is a C18 steroid derivative, with a gonane core.
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Estrogen (medication)
An estrogen is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.
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Flutamide
Flutamide, sold under the brand name Eulexin among others, is a nonsteroidal antiandrogen (NSAA) which is used primarily to treat prostate cancer.
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France
France, officially the French Republic (République française), is a sovereign state whose territory consists of metropolitan France in Western Europe, as well as several overseas regions and territories.
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In vitro
In vitro (meaning: in the glass) studies are performed with microorganisms, cells, or biological molecules outside their normal biological context.
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Intrinsic activity
Intrinsic activity (IA) or efficacy refers to the relative ability of a drug-receptor complex to produce a maximum functional response.
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Ligand (biochemistry)
In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.
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Metribolone
Metribolone (developmental code name R1881), also known as methyltrienolone, is a synthetic and orally active anabolic–androgenic steroid (AAS) and a 17α-alkylated nandrolone (19-nortestosterone) derivative which was never marketed for medical use but has been widely used in scientific research as a hot ligand in androgen receptor (AR) ligand binding assays (LBAs) and as a photoaffinity label for the AR.
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Nandrolone
Nandrolone, also known as 19-nortestosterone, is an androgen and anabolic steroid (AAS) which is used in the form of esters such as nandrolone decanoate (brand name Deca-Durabolin) and nandrolone phenylpropionate (brand name Durabolin).
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Nilutamide
Nilutamide, sold under the brand names Nilandron and Anandron, is a nonsteroidal antiandrogen (NSAA) which is used in the treatment of prostate cancer.
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Nonsteroidal antiandrogen
A nonsteroidal antiandrogen (NSAA) is an antiandrogen with a nonsteroidal chemical structure.
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Organic compound
In chemistry, an organic compound is generally any chemical compound that contains carbon.
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Partial agonist
In pharmacology, partial agonists are drugs that bind to and activate a given receptor, but have only partial efficacy at the receptor relative to a full agonist.
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Potency (pharmacology)
In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.
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Progesterone (medication)
Progesterone is a medication and naturally occurring steroid hormone.
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Progestogen
Progestogens, also sometimes spelled progestagens or gestagens, are a class of steroid hormones that bind to and activate the progesterone receptor (PR).
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Receptor antagonist
A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.
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Roussel Uclaf
Roussel Uclaf S.A. was a French pharmaceutical company and one of several predecessor companies of today's Sanofi.
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Scientific method
Scientific method is an empirical method of knowledge acquisition, which has characterized the development of natural science since at least the 17th century, involving careful observation, which includes rigorous skepticism about what one observes, given that cognitive assumptions about how the world works influence how one interprets a percept; formulating hypotheses, via induction, based on such observations; experimental testing and measurement of deductions drawn from the hypotheses; and refinement (or elimination) of the hypotheses based on the experimental findings.
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Steroid
A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.
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Steroidal antiandrogen
A steroidal antiandrogen (SAA) is an antiandrogen with a steroidal chemical structure.
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Testosterone (medication)
Testosterone is a medication and naturally occurring steroid hormone.
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Trenbolone
Trenbolone is an androgen and anabolic steroid (AAS) of the nandrolone group which itself was never marketed.
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Redirects here:
2,2,17-Trimethyltrenbolone, 2,2,17-Trimethyltrienolone, 2,2,17-trimethyltrenbolone, 2,2,17-trimethyltrienolone, 2,2-Dimethylmethyltrenbolone, 2,2-Dimethylmethyltrienolone, 2,2-Dimethylmetrenbolone, 2,2-Dimethylmetribolone, 2,2-Dimethylmetrienolone, 2,2-dimethylmethyltrenbolone, 2,2-dimethylmethyltrienolone, 2,2-dimethylmetrenbolone, 2,2-dimethylmetribolone, 2,2-dimethylmetrienolone, 2α,2β,17α-Trimethyltrenbolone, 2α,2β,17α-Trimethyltrienolone, 2α,2β,17α-trimethyltrenbolone, 2α,2β,17α-trimethyltrienolone, 2α,2β,Dimethylmethyltrenbolone, 2α,2β,Dimethylmethyltrienolone, 2α,2β,Dimethylmetrenbolone, 2α,2β,Dimethylmetribolone, 2α,2β,dimethylmethyltrenbolone, 2α,2β,dimethylmethyltrienolone, 2α,2β,dimethylmetrenbolone, 2α,2β,dimethylmetribolone, 2α,2β-Dimethylmethyltrenbolone, 2α,2β-Dimethylmethyltrienolone, 2α,2β-Dimethylmetribolone, 2α,2β-dimethylmethyltrenbolone, 2α,2β-dimethylmethyltrienolone, 2α,2β-dimethylmetribolone, R 2956, R-2956, R2956, RU 2956, RU-2956, RU2956, Trimethyltrenbolone.
References
[1] https://en.wikipedia.org/wiki/Trimethyltrienolone
