Logo
Unionpedia
Communication
Get it on Google Play
New! Download Unionpedia on your Android™ device!
Free
Faster access than browser!
 

Radafaxine

+ Save concept

Radafaxine is drug candidate designated GW-353,162 by GlaxoSmithKline, investigated for treatment of restless leg syndrome and as an NDRI antidepressant. [1]

20 relations: Bupropion, Clinical trial, Dopamine, Drug, Fatigue, G-130, GlaxoSmithKline, Hydroxybupropion, Major depressive disorder, Manifaxine, Norepinephrine, Norepinephrine–dopamine reuptake inhibitor, Obesity, Pain, Peripheral neuropathy, Phenmetrazine, Restless legs syndrome, Reuptake, Substance abuse, 2-Phenyl-3,6-dimethylmorpholine.

Bupropion

Bupropion, sold under the brand names Wellbutrin and Zyban among others, is a medication primarily used as an antidepressant and smoking cessation aid.

New!!: Radafaxine and Bupropion · See more »

Clinical trial

Clinical trials are experiments or observations done in clinical research.

New!!: Radafaxine and Clinical trial · See more »

Dopamine

Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is an organic chemical of the catecholamine and phenethylamine families that plays several important roles in the brain and body.

New!!: Radafaxine and Dopamine · See more »

Drug

A drug is any substance (other than food that provides nutritional support) that, when inhaled, injected, smoked, consumed, absorbed via a patch on the skin, or dissolved under the tongue causes a temporary physiological (and often psychological) change in the body.

New!!: Radafaxine and Drug · See more »

Fatigue

Fatigue is a subjective feeling of tiredness that has a gradual onset.

New!!: Radafaxine and Fatigue · See more »

G-130

G-130 (GP-130, 2-Phenyl-5,5-dimethyltetrahydro-1,4-oxazine) is a drug with stimulant and anorectic effects, related to phenmetrazine.

New!!: Radafaxine and G-130 · See more »

GlaxoSmithKline

GlaxoSmithKline plc (GSK) is a British pharmaceutical company headquartered in Brentford, London.

New!!: Radafaxine and GlaxoSmithKline · See more »

Hydroxybupropion

Hydroxybupropion (code name BW 306U), or 6-hydroxybupropion, is the major active metabolite of the antidepressant and smoking cessation drug bupropion.

New!!: Radafaxine and Hydroxybupropion · See more »

Major depressive disorder

Major depressive disorder (MDD), also known simply as depression, is a mental disorder characterized by at least two weeks of low mood that is present across most situations.

New!!: Radafaxine and Major depressive disorder · See more »

Manifaxine

Manifaxine (GW-320,659) is a drug developed by GlaxoSmithKline through structural modification of radafaxine, one of the major active metabolites of bupropion.

New!!: Radafaxine and Manifaxine · See more »

Norepinephrine

Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone and neurotransmitter.

New!!: Radafaxine and Norepinephrine · See more »

Norepinephrine–dopamine reuptake inhibitor

A norepinephrine–dopamine reuptake inhibitor (NDRI) is a drug that acts as a reuptake inhibitor for the neurotransmitters norepinephrine and dopamine by blocking the action of the norepinephrine transporter (NET) and the dopamine transporter (DAT), respectively.

New!!: Radafaxine and Norepinephrine–dopamine reuptake inhibitor · See more »

Obesity

Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have a negative effect on health.

New!!: Radafaxine and Obesity · See more »

Pain

Pain is a distressing feeling often caused by intense or damaging stimuli.

New!!: Radafaxine and Pain · See more »

Peripheral neuropathy

Peripheral neuropathy (PN) is damage to or disease affecting nerves, which may impair sensation, movement, gland or organ function, or other aspects of health, depending on the type of nerve affected.

New!!: Radafaxine and Peripheral neuropathy · See more »

Phenmetrazine

Phenmetrazine (INN, USAN, BAN) (brand name Preludin, and many others) is a stimulant drug that was previously used as an appetite suppressant, but has since been withdrawn from the market.

New!!: Radafaxine and Phenmetrazine · See more »

Restless legs syndrome

Restless legs syndrome (RLS) is a disorder that causes a strong urge to move one's legs.

New!!: Radafaxine and Restless legs syndrome · See more »

Reuptake

Reuptake is the reabsorption of a neurotransmitter by a neurotransmitter transporter located along the plasma membrane of an axon terminal (i.e., the pre-synaptic neuron at a synapse) or glial cell after it has performed its function of transmitting a neural impulse.

New!!: Radafaxine and Reuptake · See more »

Substance abuse

Substance abuse, also known as drug abuse, is a patterned use of a drug in which the user consumes the substance in amounts or with methods which are harmful to themselves or others, and is a form of substance-related disorder.

New!!: Radafaxine and Substance abuse · See more »

2-Phenyl-3,6-dimethylmorpholine

2-Phenyl-3,6-dimethylmorpholine is a drug with stimulant and anorectic effects, related to phenmetrazine.

New!!: Radafaxine and 2-Phenyl-3,6-dimethylmorpholine · See more »

Redirects here:

(2S,3S)-Hydroxybupropion, (2S,3S)-hydroxybupropion, (S,S)-Hydroxybupropion, (S,S)-hydroxybupropion, (SS)-Hydroxybupropion, (SS)-hydroxybupropion, 2S,3S-Hydroxybupropion, 2S,3S-hydroxybupropion, S,S-Hydroxybupropion, S,S-hydroxybupropion, SS-Hydroxybupropion, SS-hydroxybupropion.

References

[1] https://en.wikipedia.org/wiki/Radafaxine

OutgoingIncoming
Hey! We are on Facebook now! »