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Rauwolscine

Index Rauwolscine

Rauwolscine, also known as isoyohimbine, α-yohimbine, and corynanthidine, is an alkaloid found in various species within the genera Rauwolfia and Pausinystalia (formerly known as Corynanthe). [1]

21 relations: Ajmalicine, Alkaloid, Alpha-2 adrenergic receptor, Aphrodisiac, Biochemical Pharmacology (journal), Central nervous system, Corynanthine, Hydrochloride, Local anesthetic, Mouth, Partial agonist, Pausinystalia, Rauvolfia, Receptor antagonist, Spegatrine, Stereoisomerism, Stimulant, Yohimbine, 5-HT1A receptor, 5-HT2A receptor, 5-HT2B receptor.

Ajmalicine

Ajmalicine, also known as δ-yohimbine or raubasine, is an antihypertensive drug used in the treatment of high blood pressure.

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Alkaloid

Alkaloids are a class of naturally occurring chemical compounds that mostly contain basic nitrogen atoms.

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Alpha-2 adrenergic receptor

The alpha-2 (α2) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gi heterotrimeric G-protein.

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Aphrodisiac

An aphrodisiac or love drug is a substance that increases libido when consumed.

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Biochemical Pharmacology (journal)

Biochemical Pharmacology is a peer-reviewed medical journal published by Elsevier.

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Central nervous system

The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.

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Corynanthine

Corynanthine, also known as rauhimbine, is an alkaloid found in the Rauwolfia and Pausinystalia (formerly known as Corynanthe) genera of plants.

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Hydrochloride

In chemistry, a hydrochloride is an acid salt resulting, or regarded as resulting, from the reaction of hydrochloric acid with an organic base (e.g. an amine).

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Local anesthetic

A local anesthetic (LA) is a medication that causes reversible absence of pain sensation, although other senses are often affected, as well.

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Mouth

In animal anatomy, the mouth, also known as the oral cavity, buccal cavity, or in Latin cavum oris, is the opening through which many animals take in food and issue vocal sounds.

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Partial agonist

In pharmacology, partial agonists are drugs that bind to and activate a given receptor, but have only partial efficacy at the receptor relative to a full agonist.

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Pausinystalia

Pausinystalia is a largely African genus of plant in family Rubiaceae.

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Rauvolfia

Rauvolfia (sometimes spelled Rauwolfia) is a genus of evergreen trees and shrubs, commonly known as devil peppers, in the dogbane family, Apocynaceae.

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Receptor antagonist

A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.

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Spegatrine

Spegatrine is an adrenergic receptor antagonist isolated from Rauvolfia verticillata.

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Stereoisomerism

In stereochemistry, stereoisomers are isomeric molecules that have the same molecular formula and sequence of bonded atoms (constitution), but differ in the three-dimensional orientations of their atoms in space.

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Stimulant

Stimulants (also often referred to as psychostimulants or colloquially as uppers) is an overarching term that covers many drugs including those that increase activity of the central nervous system and the body, drugs that are pleasurable and invigorating, or drugs that have sympathomimetic effects.

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Yohimbine

Yohimbine is an indole alkaloid derived from the bark of the Pausinystalia yohimbe tree in Central Africa.

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5-HT1A receptor

The serotonin 1A receptor (or 5-HT1A receptor) is a subtype of serotonin receptor (5-HT receptor) that binds the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).

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5-HT2A receptor

The mammalian 5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and is a G protein-coupled receptor (GPCR).

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5-HT2B receptor

5-Hydroxytryptamine receptor 2B (5-HT2B) also known as serotonin receptor 2B is a protein that in humans is encoded by the HTR2B gene.

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References

[1] https://en.wikipedia.org/wiki/Rauwolscine

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