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106 relations: Amfepramone, Aminorex, Amphetamine, Autoreceptor, Benzylpiperazine, Binding selectivity, Cathinone, Cell membrane, Chemical synapse, Chlorphentermine, Concentration, Cytoplasm, Dexfenfluramine, Dextroamphetamine, Dipropyltryptamine, Dopamine, Dopamine releasing agent, Dopamine transporter, Drug, EC50, Ephedrine, Ethcathinone, Ethylamphetamine, Extracellular, Fenfluramine, Levofenfluramine, Levomethamphetamine, MBDB, MDMA, Membrane transport protein, Mephedrone, Meta-Chlorophenylpiperazine, Methamnetamine, Methamphetamine, Methcathinone, Methylenedioxyamphetamine, Methylone, Monoamine neurotransmitter, Monoamine reuptake inhibitor, Monoamine transporter, Naphthylaminopropane, Neuron, Neurotransmitter, Neurotransmitter receptor, Norepinephrine, Norepinephrine releasing agent, Norepinephrine transporter, Norepinephrine–dopamine releasing agent, Norfenfluramine, Norpseudoephedrine, ..., Ortho-Methylphenylpiperazine, Para-Methoxyphenylpiperazine, Passive transport, Phendimetrazine, Phenethylamine, Phenmetrazine, Phentermine, Phenylisobutylamine, Phenylpropanolamine, Propylamphetamine, Protein kinase, Pseudoephedrine, Pseudophenmetrazine, Psilocin, Release modulator, Reuptake inhibitor, Reverse transport, Serotonin, Serotonin releasing agent, Serotonin transporter, Serotonin-norepinephrine-dopamine releasing agent, Serotonin–dopamine releasing agent, Serotonin–norepinephrine releasing agent, Sigma-1 receptor, Substituted amphetamine, Substituted cathinone, Substituted phenethylamine, Substituted phenylmorpholine, Substituted piperazine, Substituted tryptamine, Synapse, Synaptic vesicle, TAAR1, Trace amine, Trifluoromethylphenylpiperazine, Trimethoxyamphetamine, Tyramine, Vesicular monoamine transporter 2, 1,3-Benzodioxolylbutanamine, 2C-E, 2C-I, 3,4-Methylenedioxy-N-ethylamphetamine, 3-Fluoroamphetamine, 3-Methylamphetamine, 4,4'-Dimethylaminorex, 4-Fluoroamphetamine, 4-Methylaminorex, 4-Methylamphetamine, 4-Methylphenethylamine, 5-Chloro-αMT, 5-Fluoro-AMT, 5-HT receptor, 5-IT, 5-MeO-aMT, 5-MeO-DMT, 6-(2-Aminopropyl)indole. Expand index (56 more) »
Amfepramone
Amfepramone is a stimulant drug of the phenethylamine, amphetamine, and cathinone classes that is used as an appetite suppressant.
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Aminorex
Aminorex (Menocil, Apiquel, aminoxaphen, aminoxafen, McN-742) is a weight loss (anorectic) stimulant drug.
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Amphetamine
Amphetamine (contracted from) is a potent central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity.
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Autoreceptor
An autoreceptor is a type of receptor located in the membranes of presynaptic nerve cells.
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Benzylpiperazine
Benzylpiperazine (BZP) is a recreational drug with euphoriant and stimulant properties. The effects produced by BZP are comparable to those produced by amphetamine. Adverse effects have been reported following its use including acute psychosis, renal toxicity and seizures. No deaths have been reported following a sole ingestion of BZP, although there have been at least two deaths from the combination of BZP and MDMA. Its sale is banned in several countries, including Australia, Canada, New Zealand, the United States, the Republic of Ireland, the United Kingdom, Bulgaria, Romania and other parts of Europe.
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Binding selectivity
Binding selectivity is defined with respect to the binding of ligands to a substrate forming a complex.
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Cathinone
Cathinone (also known as benzoylethanamine, or β-keto-amphetamine) is a monoamine alkaloid found in the shrub Catha edulis (khat) and is chemically similar to ephedrine, cathine, methcathinone and other amphetamines.
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Cell membrane
The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates the interior of all cells from the outside environment (the extracellular space).
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Chemical synapse
Chemical synapses are biological junctions through which neurons' signals can be exchanged to each other and to non-neuronal cells such as those in muscles or glands.
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Chlorphentermine
Chlorphentermine (trade names Apsedon, Desopimon, Lucofen) is a serotonergic appetite suppressant of the amphetamine family.
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Concentration
In chemistry, concentration is the abundance of a constituent divided by the total volume of a mixture.
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Cytoplasm
In cell biology, the cytoplasm is the material within a living cell, excluding the cell nucleus.
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Dexfenfluramine
Dexfenfluramine, marketed as dexfenfluramine hydrochloride under the name Redux, is a serotonergic anorectic drug: it reduces appetite by increasing the amount of extracellular serotonin in the brain.
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Dextroamphetamine
Dextroamphetamine is a potent central nervous system (CNS) stimulant and amphetamine enantiomer that is prescribed for the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy.
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Dipropyltryptamine
N,N-Dipropyltryptamine (DPT, also known as "The Light") is a psychedelic drug belonging to the tryptamine family, first reported in 1973.
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Dopamine
Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is an organic chemical of the catecholamine and phenethylamine families that plays several important roles in the brain and body.
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Dopamine releasing agent
A dopamine releasing agent (DRA) is a type of drug which induces the release of dopamine in the body and/or brain.
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Dopamine transporter
The dopamine transporter (also dopamine active transporter, DAT, SLC6A3) is a membrane-spanning protein that pumps the neurotransmitter dopamine out of the synaptic cleft back into cytosol.
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Drug
A drug is any substance (other than food that provides nutritional support) that, when inhaled, injected, smoked, consumed, absorbed via a patch on the skin, or dissolved under the tongue causes a temporary physiological (and often psychological) change in the body.
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EC50
Half maximal effective concentration (EC50) refers to the concentration of a drug, antibody or toxicant which induces a response halfway between the baseline and maximum after a specified exposure time.
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Ephedrine
Ephedrine is a medication and stimulant.
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Ethcathinone
Ethcathinone, also known as ethylpropion or ETH-CAT, is a stimulant drug of the phenethylamine, amphetamine, and cathinone chemical classes.
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Ethylamphetamine
Ethylamphetamine may refer to.
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Extracellular
In cell biology, molecular biology and related fields, the word extracellular (or sometimes extracellular space) means "outside the cell".
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Fenfluramine
Fenfluramine, formerly sold under the brand name Pondimin among others, is an appetite suppressant which was used to treat obesity and is now no longer marketed.
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Levofenfluramine
Levofenfluramine (INN), or (−)-3-trifluoromethyl-N-ethylamphetamine, also known as (−)-fenfluramine or (R)-fenfluramine, is a drug of the amphetamine family that, itself (i.e., in enantiopure form), was never marketed.
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Levomethamphetamine
LevomethamphetamineOther names include l-methamphetamine, levodesoxyephedrine, l-desoxyephedrine, levmetamfetamine (INN and USAN).
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MBDB
1,3-Benzodioxolyl-N-methylbutanamine (N-methyl-1,3-benzodioxolylbutanamine, MBDB, 3,4-methylenedioxy-N-methyl-α-ethylphenylethylamine) is an entactogen of the phenethylamine chemical class.
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MDMA
3,4-Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy (E), is a psychoactive drug used primarily as a recreational drug.
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Membrane transport protein
A membrane transport protein (or simply transporter) is a membrane protein involved in the movement of ions, small molecules, or macromolecules, such as another protein, across a biological membrane.
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Mephedrone
Mephedrone, also known as 4-methyl methcathinone (4-MMC) or 4-methyl ephedrone, is a synthetic stimulant drug of the amphetamine and cathinone classes.
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Meta-Chlorophenylpiperazine
meta-Chlorophenylpiperazine (mCPP) is a psychoactive drug of the phenylpiperazine class.
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Methamnetamine
Methamnetamine (also known as methylnaphetamine, MNA, MNT and PAL-1046) is a triple monoamine releasing agent and N-methyl analog of the non-neurotoxic experimental drug naphthylaminopropane and the naphthalene analog of methamphetamine.
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Methamphetamine
Methamphetamine (contracted from) is a potent central nervous system (CNS) stimulant that is mainly used as a recreational drug and less commonly as a second-line treatment for attention deficit hyperactivity disorder and obesity.
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Methcathinone
Methcathinone (α-methylamino-propiophenone or ephedrone) (sometimes called "cat" or "jeff" or "catnip" or "intash") is a monoamine alkaloid and psychoactive stimulant, a substituted cathinone.
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Methylenedioxyamphetamine
Methylenedioxyamphetamine may refer to.
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Methylone
Methylone (also known as "3,4-methylenedioxy-N-methylcathinone", "MDMC", "βk-MDMA" and by the slang term "M1") is an empathogen and stimulant psychoactive drug.
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Monoamine neurotransmitter
Monoamine neurotransmitters are neurotransmitters and neuromodulators that contain one amino group that is connected to an aromatic ring by a two-carbon chain (such as -CH2-CH2-). All monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, tryptophan, and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes.
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Monoamine reuptake inhibitor
A monoamine reuptake inhibitor (MRI) is a drug that acts as a reuptake inhibitor of one or more of the three major monoamine neurotransmitters serotonin, norepinephrine, and dopamine by blocking the action of one or more of the respective monoamine transporters (MATs), which include the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT).
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Monoamine transporter
Monoamine transporters (MATs) are protein structures that function as integral plasma-membrane transporters to regulate concentrations of extracellular monoamine neurotransmitters.
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Naphthylaminopropane
Naphthylisopropylamine (PAL-287) is an experimental drug currently under investigation for the treatment of alcohol and stimulant addiction.
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Neuron
A neuron, also known as a neurone (British spelling) and nerve cell, is an electrically excitable cell that receives, processes, and transmits information through electrical and chemical signals.
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Neurotransmitter
Neurotransmitters are endogenous chemicals that enable neurotransmission.
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Neurotransmitter receptor
A neurotransmitter receptor (also known as a neuroreceptor) is a membrane receptor protein that is activated by a neurotransmitter.
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Norepinephrine
Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone and neurotransmitter.
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Norepinephrine releasing agent
A norepinephrine releasing agent (NRA), also known as an adrenergic releasing agent, is a catecholaminergic type of drug which induces the release of norepinephrine (noradrenaline) and epinephrine (adrenaline) from the pre-synaptic neuron into the synapse.
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Norepinephrine transporter
The norepinephrine transporter (NET), also known as solute carrier family 6 member 2 (SLC6A2), is a protein that in humans is encoded by the SLC6A2 gene.
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Norepinephrine–dopamine releasing agent
A norepinephrine–dopamine releasing agent (NDRA) is a type of drug which induces the release of norepinephrine (and epinephrine) and dopamine in the body and/or brain.
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Norfenfluramine
Norfenfluramine, or 3-trifluoromethylamphetamine, is a never-marketed drug of the amphetamine family which behaves as a serotonin and norepinephrine releasing agent and potent 5-HT2A, 5-HT2B, and 5-HT2C agonist.
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Norpseudoephedrine
Norpseudoephedrine may refer to.
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Ortho-Methylphenylpiperazine
ortho-Methylphenylpiperazine (oMPP, oMePP), or 1-(2-methylphenyl)piperazine (2-MPP, 2-MePP), is a psychoactive and designer drug of the phenylpiperazine group.
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Para-Methoxyphenylpiperazine
para-Methoxyphenylpiperazine (MeOPP, pMPP, 4-MPP; Paraperazine) is a piperazine derivative with stimulant effects which has been sold as an ingredient in "Party pills", initially in New Zealand and subsequently in other countries around the world.
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Passive transport
Passive transport is a movement of ions and other atomic or molecular substances across cell membranes without need of energy input.
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Phendimetrazine
Phendimetrazine (Bontril, Adipost, Anorex-SR, Appecon, Melfiat, Obezine, Phendiet, Plegine, Prelu-2, Statobex) is a stimulant drug of the morpholine chemical class used as an appetite suppressant.
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Phenethylamine
Phenethylamine (PEA) is an organic compound, natural monoamine alkaloid, and trace amine which acts as a central nervous system stimulant in humans.
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Phenmetrazine
Phenmetrazine (INN, USAN, BAN) (brand name Preludin, and many others) is a stimulant drug that was previously used as an appetite suppressant, but has since been withdrawn from the market.
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Phentermine
Phentermine (contracted from phenyl-tertiary-butylamine), also known as α,α-dimethylphenethylamine, is a psychostimulant drug of the substituted amphetamine chemical class, with pharmacology similar to amphetamine.
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Phenylisobutylamine
Phenylisobutylamine, also known as α-ethylphenethylamine, Butanphenamine, B or AEPEA, is a stimulant drug of the phenethylamine class.
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Phenylpropanolamine
Phenylpropanolamine (PPA) is a sympathomimetic agent which is used as a decongestant and appetite suppressant.
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Propylamphetamine
Propylamphetamine is a psychoactive drug and research chemical of the phenethylamine and amphetamine chemical classes which acts as a stimulant.
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Protein kinase
A protein kinase is a kinase enzyme that modifies other proteins by chemically adding phosphate groups to them (phosphorylation).
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Pseudoephedrine
Pseudoephedrine (PSE) is a sympathomimetic drug of the phenethylamine and amphetamine chemical classes.
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Pseudophenmetrazine
Pseudophenmetrazine is a psychostimulant compound of the morpholine class.
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Psilocin
Psilocin (also known as 4-HO-DMT, 4-hydroxy DMT, psilocine, psilocyn, or psilotsin) is a substituted tryptamine alkaloid and a serotonergic psychedelic substance.
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Release modulator
A release modulator, or neurotransmitter release modulator, is a type of drug that modulates the release of one or more neurotransmitters.
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Reuptake inhibitor
A reuptake inhibitor (RI) is a type of drug known as a reuptake modulator that inhibits the plasmalemmal transporter-mediated reuptake of a neurotransmitter from the synapse into the pre-synaptic neuron.
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Reverse transport
Reverse transport, or transporter reversal, is a phenomenon in which the substrates of a membrane transport protein are moved in the opposite direction to that of their typical movement by the transporter.
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Serotonin
Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.
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Serotonin releasing agent
A serotonin releasing agent (SRA) is a type of drug that induces the release of serotonin into the neuronal synaptic cleft.
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Serotonin transporter
The serotonin transporter (SERT or 5-HTT) also known as the sodium-dependent serotonin transporter and solute carrier family 6 member 4 is a protein that in humans is encoded by the SLC6A4 gene.
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Serotonin-norepinephrine-dopamine releasing agent
A serotonin–norepinephrine-dopamine releasing agent (SNDRA), also known as a triple releasing agent (TRA), is a type of drug which induces the release of serotonin, norepinephrine/epinephrine, and dopamine in the brain and body.
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Serotonin–dopamine releasing agent
A serotonin–dopamine releasing agent (SDRA) is a type of drug which induces the release of serotonin and dopamine in the body and/or brain.
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Serotonin–norepinephrine releasing agent
A serotonin–norepinephrine releasing agent (SNRA) is a type of drug which induces the release of serotonin and norepinephrine (and epinephrine) in the body and/or brain.
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Sigma-1 receptor
The sigma-1 receptor (σ1R), one of two sigma receptor subtypes, is a chaperone protein at the endoplasmic reticulum (ER) that modulates calcium signaling through the IP3 receptor.
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Substituted amphetamine
Substituted amphetamines are a class of compounds based upon the amphetamine structure; it includes all derivative compounds which are formed by replacing, or substituting, one or more hydrogen atoms in the amphetamine core structure with substituents.
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Substituted cathinone
Substituted cathinones, which include some stimulants and entactogens, are derivatives of cathinone.
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Substituted phenethylamine
Substituted phenethylamines (or simply phenethylamines) are a chemical class of organic compounds that are based upon the phenethylamine structure; the class is composed of all the derivative compounds of phenethylamine which can be formed by replacing, or substituting, one or more hydrogen atoms in the phenethylamine core structure with substituents.
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Substituted phenylmorpholine
Substituted phenylmorpholines, or substituted phenmetrazines alternatively, are chemical derivatives of phenylmorpholine or of the psychostimulant drug phenmetrazine.
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Substituted piperazine
Substituted piperazines are a class of chemical compounds.
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Substituted tryptamine
Substituted tryptamines, or serotonin analogues, are organic compounds which may be thought of as being derived from tryptamine itself.
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Synapse
In the nervous system, a synapse is a structure that permits a neuron (or nerve cell) to pass an electrical or chemical signal to another neuron or to the target efferent cell.
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Synaptic vesicle
In a neuron, synaptic vesicles (or neurotransmitter vesicles) store various neurotransmitters that are released at the synapse.
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TAAR1
Trace amine-associated receptor 1 (TAAR1) is a trace amine-associated receptor (TAAR) protein that in humans is encoded by the TAAR1 gene.
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Trace amine
Trace amines are an endogenous group of trace amine-associated receptor 1 (TAAR1) agonists – and hence, monoaminergic neuromodulators – that are structurally and metabolically related to classical monoamine neurotransmitters.
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Trifluoromethylphenylpiperazine
3-Trifluoromethylphenylpiperazine (TFMPP) is a recreational drug of the piperazine chemical class.
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Trimethoxyamphetamine
TMAs, also known as trimethoxyamphetamines, are a family of isomeric psychedelic hallucinogenic drugs.
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Tyramine
Tyramine (also spelled tyramin), also known by several other names is a naturally occurring trace amine derived from the amino acid tyrosine.
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Vesicular monoamine transporter 2
The vesicular monoamine transporter 2 (VMAT2) also known as solute carrier family 18 member 2 (SLC18A2) is a protein that in humans is encoded by the SLC18A2 gene.
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1,3-Benzodioxolylbutanamine
1,3-Benzodioxolylbutanamine (also known as 3,4-methylenedioxybutanphenamine, MDB, BDB, J, and 3,4-methylenedioxy-α-ethylphenethylamine) is an entactogenic drug of the phenethylamine chemical class.
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2C-E
2C-E is a psychedelic phenethylamine of the 2C family.
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2C-I
2C-I is a psychedelic phenethylamine of the 2C family.
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3,4-Methylenedioxy-N-ethylamphetamine
3,4-Methylenedioxy-N-ethylamphetamine ("MDEA"; also called "MDE" and colloquially, "Eve") is an empathogenic psychoactive drug.
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3-Fluoroamphetamine
3-Fluoroamphetamine (3-FA; PAL-353) is a stimulant drug from the amphetamine family which acts as a monoamine releaser with similar potency to methamphetamine but more selectivity for dopamine and noradrenaline release over serotonin.
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3-Methylamphetamine
3-Methylamphetamine (3-MA; PAL-314) is a stimulant drug from the amphetamine family.
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4,4'-Dimethylaminorex
4,4'-Dimethylaminorex (abbreviated as 4,4'-DMAR), sometimes referred to by the street name "Serotoni", is a psychostimulant and entactogen designer drug related to aminorex, 4-methylaminorex and pemoline.
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4-Fluoroamphetamine
4-Fluoroamphetamine (4-FA; 4-FMP; PAL-303; "Flux"), also known as para-fluoroamphetamine (PFA) is a psychoactive research chemical of the phenethylamine and substituted amphetamine chemical classes.
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4-Methylaminorex
4-Methylaminorex (4-MAR, 4-MAX) is a stimulant drug of the 2-amino-5-aryloxazoline class that was first synthesized in 1960 by McNeil Laboratories.
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4-Methylamphetamine
4-Methylamphetamine (4-MA; PAL-313; Aptrol; p-TAP) is a stimulant and anorectic drug of the phenethylamine and amphetamine chemical classes.
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4-Methylphenethylamine
4-Methylphenethylamine (4MPEA), also known as para-methylphenethylamine, is an organic compound with the chemical formula of.
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5-Chloro-αMT
5-Chloro-α-methyltryptamine (5-Chloro-αMT), also known as PAL-542, is a tryptamine derivative related to α-methyltryptamine (αMT) and one of only a few known specific serotonin-dopamine releasing agents (SDRAs).
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5-Fluoro-AMT
5-Fluoro-α-methyltryptamine (5-Fluoro-αMT), also known as PAL-544, is a putative stimulant, entactogen, and psychedelic tryptamine derivative related to α-methyltryptamine (αMT).
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5-HT receptor
5-hydroxytryptamine receptors or 5-HT receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems.
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5-IT
5-(2-Aminopropyl)indole (5-API, 5-IT, PAL-571) is an indole and phenethylamine derivative with empathogenic effects.
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5-MeO-aMT
5-MeO-aMT or 5-methoxy-α-methyltryptamine, α,O-Dimethylserotonin (Alpha-O) is a potent psychedelic tryptamine.
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5-MeO-DMT
5-MeO-DMT (5-methoxy-N,N-dimethyltryptamine) is a psychedelic of the tryptamine class.
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6-(2-Aminopropyl)indole
6-(2-Aminopropyl)indole (6-API, 6-IT) is an indole derivative which was first identified being sold on the designer drug market by a laboratory in the Czech Republic in July 2016.
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References
[1] https://en.wikipedia.org/wiki/Monoamine_releasing_agent
