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46 relations: Agarose gel electrophoresis, Allele, Allele-specific oligonucleotide, Amplified fragment length polymorphism, Autoradiograph, Base pair, Chromosomal inversion, Chromosomal translocation, Cleaved amplified polymorphic sequence, Combined DNA Index System, Complementarity (molecular biology), Deletion (genetics), DNA, DNA database, DNA paternity testing, DNA profiling, Dot blot, Forensic science, Gel electrophoresis, Gene mapping, Genetic carrier, Genetic disorder, Genetic diversity, Genetic linkage, Genetic testing, Genetics, Homology (biology), Human Genome Project, Hybridization probe, Insertion (genetics), Molecular biology, Mutation, Nucleic acid hybridization, Oligomer restriction, Polymerase chain reaction, Polymorphism (biology), Recognition sequence, Restriction digest, Restriction enzyme, Restriction site, Single-nucleotide polymorphism, SNP genotyping, Southern blot, STR analysis, Temperature gradient gel electrophoresis, Variable number tandem repeat.
Agarose gel electrophoresis
Agarose gel electrophoresis is a method of gel electrophoresis used in biochemistry, molecular biology, genetics, and clinical chemistry to separate a mixed population of macromolecules such as DNA or proteins in a matrix of agarose, one of the two main components of agar.
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Allele
An allele is a variant form of a given gene.
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Allele-specific oligonucleotide
An allele-specific oligonucleotide (ASO) is a short piece of synthetic DNA complementary to the sequence of a variable target DNA.
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Amplified fragment length polymorphism
AFLP-PCR or just AFLP is a PCR-based tool used in genetics research, DNA fingerprinting, and in the practice of genetic engineering.
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Autoradiograph
An autoradiograph is an image on an x-ray film or nuclear emulsion produced by the pattern of decay emissions (e.g., beta particles or gamma rays) from a distribution of a radioactive substance.
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Base pair
A base pair (bp) is a unit consisting of two nucleobases bound to each other by hydrogen bonds.
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Chromosomal inversion
An inversion is a chromosome rearrangement in which a segment of a chromosome is reversed end to end.
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Chromosomal translocation
In genetics, a chromosome translocation is a chromosome abnormality caused by rearrangement of parts between nonhomologous chromosomes.
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Cleaved amplified polymorphic sequence
The cleaved amplified polymorphic sequence (CAPS) method is a technique in molecular biology for the analysis of genetic markers.
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Combined DNA Index System
The Combined DNA Index System (CODIS) is the United States national DNA database created and maintained by the Federal Bureau of Investigation.
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Complementarity (molecular biology)
In molecular biology, complementarity describes a relationship between two structures each following the lock-and-key principle.
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Deletion (genetics)
In genetics, a deletion (also called gene deletion, deficiency, or deletion mutation) (sign: Δ) is a mutation (a genetic aberration) in which a part of a chromosome or a sequence of DNA is lost during DNA replication.
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DNA
Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.
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DNA database
A DNA database or DNA databank is a database of DNA profiles which can be used in the analysis of genetic diseases, genetic fingerprinting for criminology, or genetic genealogy.
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DNA paternity testing
DNA paternity testing is the use of DNA profiling (known as genetic fingerprinting) to determine whether two individuals are biologically parent and child.
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DNA profiling
DNA profiling (also called DNA fingerprinting, DNA testing, or DNA typing) is the process of determining an individual's DNA characteristics, which are as unique as fingerprints.
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Dot blot
A dot blot (or slot blot) is a technique in molecular biology used to detect proteins.
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Forensic science
Forensic science is the application of science to criminal and civil laws, mainly—on the criminal side—during criminal investigation, as governed by the legal standards of admissible evidence and criminal procedure.
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Gel electrophoresis
Gel electrophoresis is a method for separation and analysis of macromolecules (DNA, RNA and proteins) and their fragments, based on their size and charge.
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Gene mapping
Gene mapping describes the methods used to identify the locus of a gene and the distances between genes.
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Genetic carrier
A hereditary carrier (or just carrier), is a person or other organism that has inherited a recessive allele for a genetic trait or mutation but usually does not display that trait or show symptoms of the disease.
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Genetic disorder
A genetic disorder is a genetic problem caused by one or more abnormalities in the genome.
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Genetic diversity
Genetic diversity is the total number of genetic characteristics in the genetic makeup of a species.
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Genetic linkage
Genetic linkage is the tendency of DNA sequences that are close together on a chromosome to be inherited together during the meiosis phase of sexual reproduction.
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Genetic testing
Genetic testing, also known as DNA testing, allows the determination of bloodlines and the genetic diagnosis of vulnerabilities to inherited diseases.
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Genetics
Genetics is the study of genes, genetic variation, and heredity in living organisms.
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Homology (biology)
In biology, homology is the existence of shared ancestry between a pair of structures, or genes, in different taxa.
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Human Genome Project
The Human Genome Project (HGP) was an international scientific research project with the goal of determining the sequence of nucleotide base pairs that make up human DNA, and of identifying and mapping all of the genes of the human genome from both a physical and a functional standpoint.
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Hybridization probe
In molecular biology, a hybridization probe is a fragment of DNA or RNA of variable length (usually 100–1000 bases long) which can be radioactively labeled.
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Insertion (genetics)
In genetics, an insertion (also called an insertion mutation) is the addition of one or more nucleotide base pairs into a DNA sequence.
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Molecular biology
Molecular biology is a branch of biology which concerns the molecular basis of biological activity between biomolecules in the various systems of a cell, including the interactions between DNA, RNA, proteins and their biosynthesis, as well as the regulation of these interactions.
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Mutation
In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements.
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Nucleic acid hybridization
In molecular biology, hybridization (or hybridisation) is a phenomenon in which single-stranded deoxyribonucleic acid (DNA) or ribonucleic acid (RNA) molecules anneal to complementary DNA or RNA.
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Oligomer restriction
Oligomer Restriction (abbreviated OR) is a procedure to detect an altered DNA sequence in a genome.
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Polymerase chain reaction
Polymerase chain reaction (PCR) is a technique used in molecular biology to amplify a single copy or a few copies of a segment of DNA across several orders of magnitude, generating thousands to millions of copies of a particular DNA sequence.
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Polymorphism (biology)
Polymorphism in biology and zoology is the occurrence of two or more clearly different morphs or forms, also referred to as alternative phenotypes, in the population of a species.
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Recognition sequence
The recognition sequence, sometimes also referred to as recognition site, of any DNA-binding protein motif that exhibits binding specificity, refers to the DNA sequence (or subset thereof), to which the domain is specific.
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Restriction digest
A restriction digest is a procedure used in molecular biology to prepare DNA for analysis or other processing.
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Restriction enzyme
A restriction enzyme or restriction endonuclease is an enzyme that cleaves DNA into fragments at or near specific recognition sites within the molecule known as restriction sites.
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Restriction site
Restriction sites, or restriction recognition sites, are locations on a DNA molecule containing specific (4-8 base pairs in length) sequences of nucleotides, which are recognized by restriction enzymes.
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Single-nucleotide polymorphism
A single-nucleotide polymorphism, often abbreviated to SNP (plural), is a variation in a single nucleotide that occurs at a specific position in the genome, where each variation is present to some appreciable degree within a population (e.g. > 1%).
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SNP genotyping
SNP genotyping is the measurement of genetic variations of single nucleotide polymorphisms (SNPs) between members of a species.
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Southern blot
A Southern blot is a method used in molecular biology for detection of a specific DNA sequence in DNA samples.
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STR analysis
A Short Tandem Repeat (STR) analysis is one of the most useful methods in molecular biology which is used to compare specific loci on DNA from two or more samples.
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Temperature gradient gel electrophoresis
Temperature gradient gel electrophoresis (TGGE) and denaturing gradient gel electrophoresis (DGGE) are forms of electrophoresis which use either a temperature or chemical gradient to denature the sample as it moves across an acrylamide gel.
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Variable number tandem repeat
A variable number tandem repeat (or VNTR) is a location in a genome where a short nucleotide sequence is organized as a tandem repeat.
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Redirects here:
Polymorphism (RLFP), R.F.L.P., RFLP, RFLP mapping, Restriction Fragment Length Polymorphism, Restriction Fragment Length Polymorphisms, Restriction Fragment Length Polymorphisms (RLFPs), Restriction Length Fragment Polymorphism, Restriction fragment length polymorphism (RFLP), Restriction fragment length polymorphisms, Restriction-site polymorphism, Rflp, Riflip, Riflips.
References
[1] https://en.wikipedia.org/wiki/Restriction_fragment_length_polymorphism
