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34 relations: Acetate, Acne, Androgen, Androgen receptor, Animal testing, Antigonadotropin, Benign prostatic hyperplasia, Benorterone, Binding selectivity, Bromine, Central nervous system, Chemical synthesis, Cyproterone, Cyproterone acetate, Derivative (chemistry), Dihydrotestosterone, Enzyme inhibitor, Ester, Estrogen (medication), Flutamide, Hypothalamic–pituitary–gonadal axis, List of steroidal antiandrogens, Methyl group, Oral administration, Oxygen, Partial agonist, Pattern hair loss, Progestogen, Prostate cancer, Receptor antagonist, Steroidal antiandrogen, Testosterone, Tissue (biology), 5α-Reductase.
Acetate
An acetate is a salt formed by the combination of acetic acid with an alkaline, earthy, metallic or nonmetallic and other base.
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Acne
Acne, also known as acne vulgaris, is a long-term skin disease that occurs when hair follicles are clogged with dead skin cells and oil from the skin.
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Androgen
An androgen (from Greek andr-, the stem of the word meaning "man") is any natural or synthetic steroid hormone which regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors.
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Androgen receptor
The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus.
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Animal testing
Animal testing, also known as animal experimentation, animal research and in vivo testing, is the use of non-human animals in experiments that seek to control the variables that affect the behavior or biological system under study.
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Antigonadotropin
An antigonadotropin is a drug which suppresses the activity and/or downstream effects of one or both of the gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
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Benign prostatic hyperplasia
Benign prostatic hyperplasia (BPH), also called prostate enlargement, is a noncancerous increase in size of the prostate.
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Benorterone
Benorterone, also known by its developmental code name SKF-7690 and as 17α-methyl-B-nortestosterone, is an steroidal antiandrogen which was studied for potential medical use but was never marketed.
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Binding selectivity
Binding selectivity is defined with respect to the binding of ligands to a substrate forming a complex.
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Bromine
Bromine is a chemical element with symbol Br and atomic number 35.
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Central nervous system
The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.
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Chemical synthesis
Chemical synthesis is a purposeful execution of chemical reactions to obtain a product, or several products.
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Cyproterone
Cyproterone, also known by its developmental code name SH-80881, is a steroidal antiandrogen which was studied in the 1960s and 1970s but was never introduced for medical use.
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Cyproterone acetate
Cyproterone acetate (CPA), sold alone under the brand name Androcur or with ethinylestradiol (EE) under the brand names Diane or Diane-35 among others, is an antiandrogen and progestogen which is used in the treatment of androgen-dependent conditions like acne, excessive hair growth, early puberty, and prostate cancer, as a component of feminizing hormone therapy for transgender women, and in birth control pills.
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Derivative (chemistry)
In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.
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Dihydrotestosterone
Dihydrotestosterone (DHT), or 5α-dihydrotestosterone (5α-DHT), also known as androstanolone or stanolone, is an endogenous androgen sex steroid and hormone.
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Enzyme inhibitor
4QI9) An enzyme inhibitor is a molecule that binds to an enzyme and decreases its activity.
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Ester
In chemistry, an ester is a chemical compound derived from an acid (organic or inorganic) in which at least one –OH (hydroxyl) group is replaced by an –O–alkyl (alkoxy) group.
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Estrogen (medication)
An estrogen is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.
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Flutamide
Flutamide, sold under the brand name Eulexin among others, is a nonsteroidal antiandrogen (NSAA) which is used primarily to treat prostate cancer.
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Hypothalamic–pituitary–gonadal axis
The hypothalamic–pituitary–gonadal axis (HPG axis) refers to the hypothalamus, pituitary gland, and gonadal glands as if these individual endocrine glands were a single entity.
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List of steroidal antiandrogens
This is a list of steroidal antiandrogens.
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Methyl group
A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3.
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Oral administration
| name.
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Oxygen
Oxygen is a chemical element with symbol O and atomic number 8.
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Partial agonist
In pharmacology, partial agonists are drugs that bind to and activate a given receptor, but have only partial efficacy at the receptor relative to a full agonist.
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Pattern hair loss
Pattern hair loss, known as male-pattern hair loss (MPHL) when it affects males and female-pattern hair loss (FPHL) when it affects females, is hair loss that primarily affects the top and front of the scalp.
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Progestogen
Progestogens, also sometimes spelled progestagens or gestagens, are a class of steroid hormones that bind to and activate the progesterone receptor (PR).
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Prostate cancer
Prostate cancer is the development of cancer in the prostate, a gland in the male reproductive system.
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Receptor antagonist
A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.
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Steroidal antiandrogen
A steroidal antiandrogen (SAA) is an antiandrogen with a steroidal chemical structure.
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Testosterone
Testosterone is the primary male sex hormone and an anabolic steroid.
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Tissue (biology)
In biology, tissue is a cellular organizational level between cells and a complete organ.
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5α-Reductase
5α-reductases, also known as 3-oxo-5α-steroid 4-dehydrogenases, are enzymes involved in steroid metabolism.
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Redirects here:
RO 7-2340, RO 72340, RO-7-2340, RO-72340, RO7-2340, RO72340, RO–7–2340, Ro 7-2340, Ro 72340, Ro-7-2340, Ro-72340, Ro7-2340, Ro72340, Ro–7–2340.
References
[1] https://en.wikipedia.org/wiki/BOMT
