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Robert Guthrie

Index Robert Guthrie

Robert Guthrie, MD, Ph.D. (June 28, 1916 – June 24, 1995) was an American microbiologist, best known for developing the bacterial inhibition assay used to screen infants for phenylketonuria at birth, before the development of irreversible neurological damage. [1]

29 relations: Agar, Antagonist, Antibiotic, Bacillus subtilis, Doctor of Medicine, Doctor of Philosophy, Galactose-1-phosphate uridylyltransferase deficiency, Galactosemia, Horst Bickel, Intellectual disability, Iron(III) chloride, Maple syrup urine disease, Marionville, Missouri, Metabolism, Microbiologist, Microbiology, Miles Laboratories, Missouri, Newborn screening, Phenylalanine, Phenylketonuria, Phenylpyruvic acid, Seattle, Serum (blood), United States, University of Minnesota, Urine, Washington (state), Whole blood.

Agar

Agar (pronounced, sometimes) or agar-agar is a jelly-like substance, obtained from algae.

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Antagonist

An antagonist is a character, group of characters, institution or concept that stands in or represents opposition against which the protagonist(s) must contend.

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Antibiotic

An antibiotic (from ancient Greek αντιβιοτικά, antibiotiká), also called an antibacterial, is a type of antimicrobial drug used in the treatment and prevention of bacterial infections.

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Bacillus subtilis

Bacillus subtilis, known also as the hay bacillus or grass bacillus, is a Gram-positive, catalase-positive bacterium, found in soil and the gastrointestinal tract of ruminants and humans.

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Doctor of Medicine

A Doctor of Medicine (MD from Latin Medicinae Doctor) is a medical degree, the meaning of which varies between different jurisdictions.

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Doctor of Philosophy

A Doctor of Philosophy (PhD or Ph.D.; Latin Philosophiae doctor) is the highest academic degree awarded by universities in most countries.

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Galactose-1-phosphate uridylyltransferase deficiency

Galactose-1-phosphate uridylyltransferase deficiency, also called galactosemia type 1, classic galactosemia or GALT deficiency, is the most common type of galactosemia, an inborn error of galactose metabolism, caused by a deficiency of the enzyme galactose-1-phosphate uridylyltransferase.

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Galactosemia

Galactosemia (British galactosaemia, from Greek γαλακτόζη + αίμα, meaning galactose + blood, accumulation of galactose in blood) is a rare genetic metabolic disorder that affects an individual's ability to metabolize the sugar galactose properly.

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Horst Bickel

Horst Bickel (28 June 1918 – 1 December 2000) was a German doctor.

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Intellectual disability

Intellectual disability (ID), also known as general learning disability, and mental retardation (MR), is a generalized neurodevelopmental disorder characterized by significantly impaired intellectual and adaptive functioning.

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Iron(III) chloride

Iron(III) chloride, also called ferric chloride, is an industrial scale commodity chemical compound, with the formula FeCl3 and with iron in the +3 oxidation state.

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Maple syrup urine disease

Maple syrup urine disease (MSUD), also called branched-chain ketoaciduria, is an autosomal recessive metabolic disorder affecting branched-chain amino acids.

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Marionville, Missouri

Marionville is a city in Lawrence County, Missouri, United States.

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Metabolism

Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical transformations within the cells of organisms.

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Microbiologist

A microbiologist (from Greek μῑκρος) is a scientist who studies microscopic life forms and processes.

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Microbiology

Microbiology (from Greek μῑκρος, mīkros, "small"; βίος, bios, "life"; and -λογία, -logia) is the study of microorganisms, those being unicellular (single cell), multicellular (cell colony), or acellular (lacking cells).

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Miles Laboratories

Miles Laboratories was founded as the Dr.

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Missouri

Missouri is a state in the Midwestern United States.

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Newborn screening

Newborn screening is a public health program of screening in infants shortly after birth for a list of conditions that are treatable, but not clinically evident in the newborn period.

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Phenylalanine

Phenylalanine (symbol Phe or F) is an α-amino acid with the formula.

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Phenylketonuria

Phenylketonuria (PKU) is an inborn error of metabolism that results in decreased metabolism of the amino acid phenylalanine.

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Phenylpyruvic acid

Phenylpyruvic acid is the organic compound with the formula C6H5CH2C(O)CO2H.

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Seattle

Seattle is a seaport city on the west coast of the United States.

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Serum (blood)

In blood, the serum is the component that is neither a blood cell (serum does not contain white or red blood cells) nor a clotting factor; it is the blood plasma not including the fibrinogens.

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United States

The United States of America (USA), commonly known as the United States (U.S.) or America, is a federal republic composed of 50 states, a federal district, five major self-governing territories, and various possessions.

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University of Minnesota

The University of Minnesota, Twin Cities (often referred to as the University of Minnesota, Minnesota, the U of M, UMN, or simply the U) is a public research university in Minneapolis and Saint Paul, Minnesota.

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Urine

Urine is a liquid by-product of metabolism in humans and in many animals.

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Washington (state)

Washington, officially the State of Washington, is a state in the Pacific Northwest region of the United States.

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Whole blood

Whole blood (WB) is human blood from a standard blood donation.

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Guthrie, Robert, R Guthrie.

References

[1] https://en.wikipedia.org/wiki/Robert_Guthrie

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