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Rosonabant

Index Rosonabant

Rosonabant (INN; E-6776) is a drug acting as a CB1 receptor antagonist/inverse agonist that was under investigation by Esteve as an appetite suppressant for the treatment of obesity. [1]

16 relations: Adverse effect, Anorectic, Anxiety, Cannabinoid receptor antagonist, Cannabinoid receptor type 1, Clinic, Drug, Esteve, International nonproprietary name, Inverse agonist, Major depressive disorder, Obesity, Psychiatry, Receptor antagonist, Rimonabant, Suicidal ideation.

Adverse effect

In medicine, an adverse effect is an undesired harmful effect resulting from a medication or other intervention such as surgery.

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Anorectic

An anorectic or anorexic is a drug which reduces appetite, resulting in lower food consumption, leading to weight loss.

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Anxiety

Anxiety is an emotion characterized by an unpleasant state of inner turmoil, often accompanied by nervous behaviour such as pacing back and forth, somatic complaints, and rumination.

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Cannabinoid receptor antagonist

A cannabinoid receptor antagonist, also known simply as a cannabinoid antagonist or as an anticannabinoid, is a type of cannabinoidergic drug that binds to cannabinoid receptors (CBR) and prevents their activation by endocannabinoids.

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Cannabinoid receptor type 1

The cannabinoid type 1 receptor, often abbreviated as CB1, is a G protein-coupled cannabinoid receptor located in the central and peripheral nervous system.

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Clinic

A clinic (or outpatient clinic or ambulatory care clinic) is a healthcare facility that is primarily focused on the care of outpatients.

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Drug

A drug is any substance (other than food that provides nutritional support) that, when inhaled, injected, smoked, consumed, absorbed via a patch on the skin, or dissolved under the tongue causes a temporary physiological (and often psychological) change in the body.

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Esteve

Esteve is a Spanish international pharmaceutical company headquartered in Barcelona.

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International nonproprietary name

The International Nonproprietary Name (INN) is an official generic and non-proprietary name given to a pharmaceutical drug or an active ingredient.

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Inverse agonist

In the field of pharmacology, an inverse agonist is an agent that binds to the same receptor as an agonist but induces a pharmacological response opposite to that agonist.

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Major depressive disorder

Major depressive disorder (MDD), also known simply as depression, is a mental disorder characterized by at least two weeks of low mood that is present across most situations.

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Obesity

Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have a negative effect on health.

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Psychiatry

Psychiatry is the medical specialty devoted to the diagnosis, prevention and treatment of mental disorders.

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Receptor antagonist

A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.

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Rimonabant

Rimonabant (also known as SR141716; trade names Acomplia, Zimulti) is an anorectic antiobesity drug that was first approved in Europe in 2006 but was withdrawn worldwide in 2008 due to serious psychiatric side effects; it was never approved in the United States.

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Suicidal ideation

Suicidal ideation, also known as suicidal thoughts, is thinking about or having an unusual preoccupation with suicide.

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Redirects here:

C21H21Cl3N4O, E 6776, E-6776, E6776.

References

[1] https://en.wikipedia.org/wiki/Rosonabant

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