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Rosonabant (INN; E-6776) is a drug acting as a CB1 receptor antagonist/inverse agonist that was under investigation by Esteve as an appetite suppressant for the treatment of obesity. [1]

16 relations: Adverse effect, Anorectic, Anxiety, Cannabinoid receptor antagonist, Cannabinoid receptor type 1, Clinic, Drug, Esteve, International Nonproprietary Name, Inverse agonist, Major depressive disorder, Obesity, Psychiatry, Receptor antagonist, Rimonabant, Suicidal ideation.

Adverse effect

In medicine, an adverse effect is an undesired harmful effect resulting from a medication or other intervention such as surgery.

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An anorectic or anorexic (from the Greek an-.

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Anxiety is an emotion characterized by an unpleasant state of inner turmoil, often accompanied by nervous behavior, such as pacing back and forth, somatic complaints and rumination.

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Cannabinoid receptor antagonist

The discovery of the endogenous cannabinoid system led to the development of CB1 receptor antagonists.

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Cannabinoid receptor type 1

The cannabinoid receptor type 1, often abbreviated as CB1, is a G protein-coupled cannabinoid receptor located primarily in the central and peripheral nervous system.

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A clinic (or outpatient clinic or ambulatory care clinic) is a health care facility that is primarily devoted to the care of outpatients.

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A drug is, in the broadest of terms, a chemical substance that has known biological effects on humans or other animals.

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Esteve is a Catalan international pharmaceutical company headquartered in Barcelona.

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International Nonproprietary Name

An International Nonproprietary Name (INN) is an official generic and nonproprietary name given to a pharmaceutical drug or active ingredient.

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Inverse agonist

In the field of pharmacology, an inverse agonist is an agent that binds to the same receptor as an agonist but induces a pharmacological response opposite to that agonist.

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Major depressive disorder

Major depressive disorder (MDD) (also known as clinical depression, major depression, unipolar depression, or unipolar disorder; or as recurrent depression in the case of repeated episodes) is a mental disorder characterized by a pervasive and persistent low mood that is accompanied by low self-esteem and by a loss of interest or pleasure in normally enjoyable activities.

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Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have a negative effect on health, leading to reduced life expectancy and/or increased health problems.

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Psychiatry is the medical specialty devoted to the study, diagnosis, treatment, and prevention of mental disorders.

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Receptor antagonist

A receptor antagonist is a type of receptor ligand or drug that blocks or dampens agonist-mediated responses rather than provoking a biological response itself upon binding to a receptor.

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Rimonabant (also known as SR141716; trade name Acomplia) is an anorectic antiobesity drug that has been withdrawn from the market due to potentially serious side effects.

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Suicidal ideation

Suicidal ideation, also known as suicidal thoughts, concerns thoughts about or an unusual preoccupation with suicide.

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Redirects here:

C21H21Cl3N4O, E 6776, E-6776, E6776.


[1] https://en.wikipedia.org/wiki/Rosonabant

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