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Ryanodine receptor

Index Ryanodine receptor

Ryanodine receptors (RyRs) form a class of intracellular calcium channels in various forms of excitable animal tissue like muscles and neurons. [1]

65 relations: Alkaloid, Alpha-1D adrenergic receptor, Alzheimer's disease, Antibody, Arrhythmogenic right ventricular dysplasia, ASPH, Brain, Caffeine, Calcium, Calcium channel, Calcium in biology, Calcium sparks, Calcium-induced calcium release, Calsequestrin, Cardiac muscle, Cav1.1, Cell (biology), Central core disease, Cyclic ADP-ribose, Dantrolene, Endoplasmic reticulum, FKBP1B, G protein–coupled receptor, Heart, Heart arrhythmia, HOMER1, Inositol trisphosphate, Inositol trisphosphate receptor, L-type calcium channel, Malignant hyperthermia, Metabotropic glutamate receptor 1, Mole (unit), Muscle, Muscle contraction, Mutation, Myasthenia gravis, Myocyte, Neurodegeneration, Neuron, P-Chlorocresol, Pancreas, PC12 cell line, Pentifylline, Phospholipase C, Polymorphism (biology), Positive feedback, Procaine, PSEN1, Receptor (biochemistry), Receptor tyrosine kinase, ..., Ruthenium red, Ryanodine, Ryanodine receptor 2, Ryanoid, RYR1, RYR3, Sarcoplasmic reticulum, Serum (blood), Skeletal muscle, Suramin, Tacrolimus, Tetracaine, Tissue (biology), Triadin, Ventricular tachycardia. Expand index (15 more) »

Alkaloid

Alkaloids are a class of naturally occurring chemical compounds that mostly contain basic nitrogen atoms.

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Alpha-1D adrenergic receptor

The alpha-1D adrenergic receptor (α1D adrenoreceptor), also known as ADRA1D, is an alpha-1 adrenergic receptor, and also denotes the human gene encoding it.

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Alzheimer's disease

Alzheimer's disease (AD), also referred to simply as Alzheimer's, is a chronic neurodegenerative disease that usually starts slowly and worsens over time.

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Antibody

An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses.

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Arrhythmogenic right ventricular dysplasia

Arrhythmogenic right ventricular dysplasia (ARVD), or arrhythmogenic right ventricular cardiomyopathy (ARVC), is an inherited heart disease.

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ASPH

Aspartyl/asparaginyl beta-hydroxylase (HAAH) is an enzyme that in humans is encoded by the ASPH gene.

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Brain

The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals.

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Caffeine

Caffeine is a central nervous system (CNS) stimulant of the methylxanthine class.

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Calcium

Calcium is a chemical element with symbol Ca and atomic number 20.

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Calcium channel

A calcium channel is an ion channel which shows selective permeability to calcium ions.

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Calcium in biology

Calcium ions (Ca2+) play a vital role in the physiology and biochemistry of organisms and the cell.

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Calcium sparks

A calcium spark is the microscopic release of calcium (Ca2+) from a store known as the sarcoplasmic reticulum (SR), located within muscle cells.

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Calcium-induced calcium release

Calcium-induced calcium release (CICR) describes a biological process whereby calcium is able to activate calcium release from intracellular Ca2+ stores (e.g., endoplasmic reticulum or sarcoplasmic reticulum).

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Calsequestrin

Calsequestrin is a calcium-binding protein that acts as a calcium buffer within the sarcoplasmic reticulum.

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Cardiac muscle

Cardiac muscle (heart muscle) is one of the three major types of muscle, the others being skeletal and smooth muscle.

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Cav1.1

Cav1.1 also known as the calcium channel, voltage-dependent, L type, alpha 1S subunit, (CACNA1S), is a protein which in humans is encoded by the CACNA1S gene.

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Cell (biology)

The cell (from Latin cella, meaning "small room") is the basic structural, functional, and biological unit of all known living organisms.

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Central core disease

Central core disease (CCD), also known as central core myopathy, is an autosomal dominant congenital myopathy (inborn muscle disorder).

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Cyclic ADP-ribose

Cyclic ADP Ribose, frequently abbreviated as cADPR, is a cyclic adenine nucleotide (like cAMP) with two phosphate groups present on 5' OH of the adenosine (like ADP), further connected to another ribose at the 5' position, which, in turn, closes the cycle by glycosidic bonding to the nitrogen 1 (N1) of the same adenine base (whose position N9 has the glycosidic bond to the other ribose).

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Dantrolene

Dantrolene sodium is a postsynaptic muscle relaxant that lessens excitation-contraction coupling in muscle cells.

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Endoplasmic reticulum

The endoplasmic reticulum (ER) is a type of organelle found in eukaryotic cells that forms an interconnected network of flattened, membrane-enclosed sacs or tube-like structures known as cisternae.

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FKBP1B

Peptidyl-prolyl cis-trans isomerase FKBP1B is an enzyme that in humans is encoded by the FKBP1B gene.

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G protein–coupled receptor

G protein–coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses.

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Heart

The heart is a muscular organ in most animals, which pumps blood through the blood vessels of the circulatory system.

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Heart arrhythmia

Heart arrhythmia (also known as arrhythmia, dysrhythmia, or irregular heartbeat) is a group of conditions in which the heartbeat is irregular, too fast, or too slow.

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HOMER1

Homer protein homolog 1 or Homer1 is a neuronal protein that in humans is encoded by the HOMER1 gene.

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Inositol trisphosphate

Inositol trisphosphate or inositol 1,4,5-trisphosphate (also commonly known as triphosphoinositol; abbreviated InsP3 or Ins3P or IP3), together with diacylglycerol (DAG), is a secondary messenger molecule used in signal transduction and lipid signaling in biological cells.

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Inositol trisphosphate receptor

Inositol trisphosphate receptor (InsP3R) is a membrane glycoprotein complex acting as a Ca2+ channel activated by inositol trisphosphate (InsP3).

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L-type calcium channel

The L-type calcium channel (also known as the dihydropyridine channel, or DHP channel) is part of the high-voltage activated family of voltage-dependent calcium channel.

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Malignant hyperthermia

Malignant hyperthermia (MH) is a type of severe reaction that occurs to particular medications used during general anesthesia, among those who are susceptible.

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Metabotropic glutamate receptor 1

The glutamate receptor, metabotropic 1, also known as GRM1, is a human gene which encodes the metabotropic glutamate receptor 1 (mGluR1) protein.

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Mole (unit)

The mole, symbol mol, is the SI unit of amount of substance.

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Muscle

Muscle is a soft tissue found in most animals.

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Muscle contraction

Muscle contraction is the activation of tension-generating sites within muscle fibers.

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Mutation

In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements.

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Myasthenia gravis

Myasthenia gravis (MG) is a long-term neuromuscular disease that leads to varying degrees of skeletal muscle weakness.

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Myocyte

A myocyte (also known as a muscle cell) is the type of cell found in muscle tissue.

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Neurodegeneration

Neurodegeneration is the progressive loss of structure or function of neurons, including death of neurons.

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Neuron

A neuron, also known as a neurone (British spelling) and nerve cell, is an electrically excitable cell that receives, processes, and transmits information through electrical and chemical signals.

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P-Chlorocresol

p-Chlorocresol (p-chloro-m-cresol; PCMC; brand name: Preventol CMK) is a chlorinated phenol which is used as an antiseptic and preservative.

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Pancreas

The pancreas is a glandular organ in the digestive system and endocrine system of vertebrates.

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PC12 cell line

PC12 is a cell line derived from a pheochromocytoma of the rat adrenal medulla, that have an embryonic origin from the neural crest that has a mixture of neuroblastic cells and eosinophilic cells.

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Pentifylline

Pentifylline (marketed as Cosaldon) is a vasodilator.

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Phospholipase C

Phospholipase C (PLC) is a class of membrane-associated enzymes that cleave phospholipids just before the phosphate group (see figure).

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Polymorphism (biology)

Polymorphism in biology and zoology is the occurrence of two or more clearly different morphs or forms, also referred to as alternative phenotypes, in the population of a species.

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Positive feedback

Positive feedback is a process that occurs in a feedback loop in which the effects of a small disturbance on a system include an increase in the magnitude of the perturbation.

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Procaine

Procaine is a local anesthetic drug of the amino ester group.

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PSEN1

Presenilin-1 (PS-1) is a presenilin protein that in humans is encoded by the PSEN1 gene.

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Receptor (biochemistry)

In biochemistry and pharmacology, a receptor is a protein molecule that receives chemical signals from outside a cell.

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Receptor tyrosine kinase

Receptor tyrosine kinases (RTKs) are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones.

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Ruthenium red

The inorganic dye ammoniated ruthenium oxychloride, also known as ruthenium red, is used in histology to stain aldehyde fixed mucopolysaccharides.

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Ryanodine

Ryanodine is a poisonous diterpenoid found in the South American plant Ryania speciosa (Salicaceae).

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Ryanodine receptor 2

Ryanodine receptor 2 (RYR2) is a protein found primarily in cardiac muscle.

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Ryanoid

Ryanoids are a class of insecticides which share the same mechanism of action as the alkaloid ryanodine.

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RYR1

Ryanodine receptor 1 (RYR-1) also known as skeletal muscle calcium release channel or skeletal muscle-type ryanodine receptor is a protein found primarily in skeletal muscle.

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RYR3

Ryanodine receptor 3 is a protein that in humans is encoded by the RYR3 gene.

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Sarcoplasmic reticulum

The sarcoplasmic reticulum (SR) is a membrane-bound structure found within muscle cells that is similar to the endoplasmic reticulum in other cells.

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Serum (blood)

In blood, the serum is the component that is neither a blood cell (serum does not contain white or red blood cells) nor a clotting factor; it is the blood plasma not including the fibrinogens.

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Skeletal muscle

Skeletal muscle is one of three major muscle types, the others being cardiac muscle and smooth muscle.

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Suramin

Suramin is a medication used to treat African sleeping sickness and river blindness.

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Tacrolimus

No description.

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Tetracaine

Tetracaine, also known as amethocaine, is a local anesthetic used to numb the eyes, nose, or throat.

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Tissue (biology)

In biology, tissue is a cellular organizational level between cells and a complete organ.

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Triadin

Triadin, also known as TRDN, is a human gene associated with the release of Calcium ions from the sarcoplasmic reticulum triggering muscular contraction through calcium-induced calcium release.

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Ventricular tachycardia

Ventricular tachycardia (V-tach or VT) is a type of regular and fast heart rate that arises from improper electrical activity in the ventricles of the heart.

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Redirects here:

Calcium induced calcium release, RyR, RyR1, RyR3, Ryanodine receptor calcium release channel, Ryanodine-inositol-1,4,5-trisphosphate receptor Ca2+ channel.

References

[1] https://en.wikipedia.org/wiki/Ryanodine_receptor

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