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Esketamine

Index Esketamine

Esketamine, also known as (S)-ketamine or S(+)-ketamine and sold under the brand names Ketanest and Ketanest S among others, is a general anesthetic and a dissociative hallucinogen. [1]

56 relations: Analgesic, Anaphylaxis, Anesthesia, Antidepressant, Arketamine, Austria, Breakthrough therapy, Bronchospasm, Burn, Caesarean section, Cardiac tamponade, Clinical trial, Constrictive pericarditis, Denmark, Dissociative, Dopamine reuptake inhibitor, Dopamine transporter, Enantiomer, Estonia, Europe, Finland, Food and Drug Administration, Frontal lobe, General anaesthetic, Germany, Glucose, Hallucinogen, Hydrochloride, Hypovolemia, Intravenous therapy, Johnson & Johnson, Ketamine, List of investigational antidepressants, Liver disease, Local anesthesia, Major depressive disorder, Nasal spray, Nerve block, Netherlands, New Drug Application, NMDA receptor, NMDA receptor antagonist, Norway, Pharmacodynamics, Racemic mixture, Rapastinel, Septic shock, Sigma receptor, Slovenia, Suicidal ideation, ..., Sweden, Switzerland, Trademark distinctiveness, Treatment-resistant depression, United States, Veterinary medicine. Expand index (6 more) »

Analgesic

An analgesic or painkiller is any member of the group of drugs used to achieve analgesia, relief from pain.

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Anaphylaxis

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.

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Anesthesia

In the practice of medicine (especially surgery and dentistry), anesthesia or anaesthesia (from Greek "without sensation") is a state of temporary induced loss of sensation or awareness.

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Antidepressant

Antidepressants are drugs used for the treatment of major depressive disorder and other conditions, including dysthymia, anxiety disorders, obsessive–compulsive disorder, eating disorders, chronic pain, neuropathic pain and, in some cases, dysmenorrhoea, snoring, migraine, attention-deficit hyperactivity disorder (ADHD), addiction, dependence, and sleep disorders.

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Arketamine

Arketamine, also (R)-ketamine or (R)-(&minus)-ketamine, is the (R)-(&minus) enantiomer of ketamine.

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Austria

Austria (Österreich), officially the Republic of Austria (Republik Österreich), is a federal republic and a landlocked country of over 8.8 million people in Central Europe.

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Breakthrough therapy

Breakthrough therapy is a United States Food and Drug Administration designation that expedites drug development that was created by Congress under Section 902 of the 9 July 2012 Food and Drug Administration Safety and Innovation Act.

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Bronchospasm

Bronchospasm or a bronchial spasm is a sudden constriction of the muscles in the walls of the bronchioles.

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Burn

A burn is a type of injury to skin, or other tissues, caused by heat, cold, electricity, chemicals, friction, or radiation.

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Caesarean section

Caesarean section, also known as C-section or caesarean delivery, is the use of surgery to deliver one or more babies.

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Cardiac tamponade

Cardiac tamponade, also known as pericardial tamponade, is when fluid in the pericardium (the sac around the heart) builds up, resulting in compression of the heart.

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Clinical trial

Clinical trials are experiments or observations done in clinical research.

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Constrictive pericarditis

Constrictive pericarditis is a medical condition characterized by a thickened, fibrotic pericardium, limiting the heart's ability to function normally.

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Denmark

Denmark (Danmark), officially the Kingdom of Denmark,Kongeriget Danmark,.

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Dissociative

Dissociatives are a class of hallucinogen, which distort perceptions of sight and sound and produce feelings of detachment – dissociation – from the environment and self.

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Dopamine reuptake inhibitor

A dopamine reuptake inhibitor (DRI) is a class of drug which acts as a reuptake inhibitor of the monoamine neurotransmitter dopamine by blocking the action of the dopamine transporter (DAT).

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Dopamine transporter

The dopamine transporter (also dopamine active transporter, DAT, SLC6A3) is a membrane-spanning protein that pumps the neurotransmitter dopamine out of the synaptic cleft back into cytosol.

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Enantiomer

In chemistry, an enantiomer, also known as an optical isomer (and archaically termed antipode or optical antipode), is one of two stereoisomers that are mirror images of each other that are non-superposable (not identical), much as one's left and right hands are the same except for being reversed along one axis (the hands cannot be made to appear identical simply by reorientation).

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Estonia

Estonia (Eesti), officially the Republic of Estonia (Eesti Vabariik), is a sovereign state in Northern Europe.

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Europe

Europe is a continent located entirely in the Northern Hemisphere and mostly in the Eastern Hemisphere.

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Finland

Finland (Suomi; Finland), officially the Republic of Finland is a country in Northern Europe bordering the Baltic Sea, Gulf of Bothnia, and Gulf of Finland, between Norway to the north, Sweden to the northwest, and Russia to the east.

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Food and Drug Administration

The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.

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Frontal lobe

The frontal lobe, located at the front of the brain, is the largest of the four major lobes of the cerebral cortex in the mammalian brain.

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General anaesthetic

General anaesthetics (or anesthetics, see spelling differences) are often defined as compounds that induce a reversible loss of consciousness in humans or loss of righting reflex in animals.

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Germany

Germany (Deutschland), officially the Federal Republic of Germany (Bundesrepublik Deutschland), is a sovereign state in central-western Europe.

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Glucose

Glucose is a simple sugar with the molecular formula C6H12O6.

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Hallucinogen

A hallucinogen is a psychoactive agent which can cause hallucinations, perceptual anomalies, and other substantial subjective changes in thoughts, emotion, and consciousness.

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Hydrochloride

In chemistry, a hydrochloride is an acid salt resulting, or regarded as resulting, from the reaction of hydrochloric acid with an organic base (e.g. an amine).

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Hypovolemia

Hypovolemia is a state of decreased blood volume; more specifically, decrease in volume of blood plasma.

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Intravenous therapy

Intravenous therapy (IV) is a therapy that delivers liquid substances directly into a vein (intra- + ven- + -ous).

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Johnson & Johnson

Johnson & Johnson is an American multinational medical devices, pharmaceutical and consumer packaged goods manufacturing company founded in 1886.

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Ketamine

Ketamine, sold under the brand name Ketalar among others, is a medication mainly used for starting and maintaining anesthesia.

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List of investigational antidepressants

This is a list of investigational antidepressants, or antidepressants that are currently under development for clinical use in the treatment of mood disorders but are not yet approved.

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Liver disease

Liver disease (also called hepatic disease) is a type of damage to or disease of the liver.

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Local anesthesia

Local anesthesia is any technique to induce the absence of sensation in a specific part of the body, generally for the aim of inducing local analgesia, that is, local insensitivity to pain, although other local senses may be affected as well.

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Major depressive disorder

Major depressive disorder (MDD), also known simply as depression, is a mental disorder characterized by at least two weeks of low mood that is present across most situations.

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Nasal spray

Nasal sprays, or nasal drops, are used as local treatments for conditions such as nasal congestion and allergic rhinitis.

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Nerve block

Nerve block or regional nerve blockade is any deliberate interruption of signals traveling along a nerve, often for the purpose of pain relief.

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Netherlands

The Netherlands (Nederland), often referred to as Holland, is a country located mostly in Western Europe with a population of seventeen million.

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New Drug Application

The Food and Drug Administration's New Drug Application (NDA) is the vehicle in the United States through which drug sponsors formally propose that the FDA approve a new pharmaceutical for sale and marketing.

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NMDA receptor

The N-methyl-D-aspartate receptor (also known as the NMDA receptor or NMDAR), is a glutamate receptor and ion channel protein found in nerve cells.

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NMDA receptor antagonist

NMDA receptor antagonists are a class of anesthetics that work to antagonize, or inhibit the action of, the ''N''-Methyl-D-aspartate receptor (NMDAR).

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Norway

Norway (Norwegian: (Bokmål) or (Nynorsk); Norga), officially the Kingdom of Norway, is a unitary sovereign state whose territory comprises the western portion of the Scandinavian Peninsula plus the remote island of Jan Mayen and the archipelago of Svalbard.

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Pharmacodynamics

Pharmacodynamics is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs).

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Racemic mixture

In chemistry, a racemic mixture, or racemate, is one that has equal amounts of left- and right-handed enantiomers of a chiral molecule.

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Rapastinel

Rapastinel (former developmental code names GLYX-13, BV-102) is a novel antidepressant that is under development by Allergan (previously Naurex) as an adjunctive therapy for the treatment of treatment-resistant major depressive disorder.

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Septic shock

Septic shock is a serious medical condition that occurs when sepsis, which is organ injury or damage in response to infection, leads to dangerously low blood pressure and abnormalities in cellular metabolism.

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Sigma receptor

Schematic σ receptor The sigma receptors σ1 and σ2 bind to ligands such as 4-PPBP (4-phenyl-1-(4-phenylbutyl) piperidine), SA 4503 (cutamesine), ditolylguanidine, dimethyltryptamine, and siramesine.

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Slovenia

Slovenia (Slovenija), officially the Republic of Slovenia (Slovene:, abbr.: RS), is a country in southern Central Europe, located at the crossroads of main European cultural and trade routes.

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Suicidal ideation

Suicidal ideation, also known as suicidal thoughts, is thinking about or having an unusual preoccupation with suicide.

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Sweden

Sweden (Sverige), officially the Kingdom of Sweden (Swedish), is a Scandinavian country in Northern Europe.

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Switzerland

Switzerland, officially the Swiss Confederation, is a sovereign state in Europe.

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Trademark distinctiveness

Trademark distinctiveness is an important concept in the law governing trademarks and service marks.

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Treatment-resistant depression

Treatment-resistant depression (TRD) or treatment-refractory depression is a term used in clinical psychiatry to describe cases of major depressive disorder (MDD) that do not respond adequately to appropriate courses of at least two antidepressants.

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United States

The United States of America (USA), commonly known as the United States (U.S.) or America, is a federal republic composed of 50 states, a federal district, five major self-governing territories, and various possessions.

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Veterinary medicine

Veterinary medicine is the branch of medicine that deals with the prevention, diagnosis and treatment of disease, disorder and injury in non-human animals.

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Redirects here:

(S)-Ketamine, (S)-ketamine, ATC code N01AX14, ATCvet code QN01AX14, Esketamine HCl, Esketamine hydrochloride, JNJ 54135419, JNJ-54135419, JNJ54135419, Ketanest S, Ketanest-S, S(+)-Ketamine, S(+)-ketamine, S-Ketamine, S-ketamine.

References

[1] https://en.wikipedia.org/wiki/Esketamine

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