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SKI protein

Index SKI protein

The SKI protein is a nuclear proto-oncogene that is associated with tumors at high cellular concentrations. [1]

39 relations: Amino acid, Apoptosis, Blastomere, C-terminus, Cell fate determination, Cell growth, Cervical cancer, CREB, Cysteine, Fibroblast, Gene expression, Helix-turn-helix, HIPK2, Histidine, Leucine, Leucine zipper, MECP2, Melanoma, Memorial Sloan Kettering Cancer Center, Mothers against decapentaplegic homolog 1, Mothers against decapentaplegic homolog 2, Mothers against decapentaplegic homolog 3, Mothers against decapentaplegic homolog 4, NFIX, Oligomer, P73, Phenylalanine, Proline, Promyelocytic leukemia protein, Protein domain, Protein–protein interaction, R-SMAD, SKIL, SNW1, Structural motif, TGF beta signaling pathway, Transcription coregulator, Transforming growth factor beta, Zinc finger.

Amino acid

Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.

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Apoptosis

Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.

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Blastomere

In biology, blastocoel is a type of cell produced by cleavage (cell division) of the zygote after fertilization and is an essential part of blastula formation.

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C-terminus

The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH).

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Cell fate determination

Within the field of developmental biology one goal is to understand how a particular cell (or embryo) develops into the final cell type (or organism), essentially how a cell's fate is determined.

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Cell growth

The term cell growth is used in the contexts of biological cell development and cell division (reproduction).

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Cervical cancer

Cervical cancer is a cancer arising from the cervix.

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CREB

CREB (cAMP response element-binding protein) is a cellular transcription factor.

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Cysteine

Cysteine (symbol Cys or C) is a semi-essential proteinogenic amino acid with the formula HO2CCH(NH2)CH2SH.

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Fibroblast

A fibroblast is a type of biological cell that synthesizes the extracellular matrix and collagen, the structural framework (stroma) for animal tissues, and plays a critical role in wound healing.

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Gene expression

Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product.

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Helix-turn-helix

In proteins, the helix-turn-helix (HTH) is a major structural motif capable of binding DNA.

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HIPK2

Homeodomain-interacting protein kinase 2 is an enzyme that in humans is encoded by the HIPK2 gene.

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Histidine

Histidine (symbol His or H) is an α-amino acid that is used in the biosynthesis of proteins.

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Leucine

Leucine (symbol Leu or L) is an essential amino acid that is used in the biosynthesis of proteins.

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Leucine zipper

A leucine zipper (or leucine scissors) is a common three-dimensional structural motif in proteins.

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MECP2

MECP2 (methyl CpG binding protein 2 (Rett syndrome)) is a gene that encodes the protein MECP2.

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Melanoma

Melanoma, also known as malignant melanoma, is a type of cancer that develops from the pigment-containing cells known as melanocytes.

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Memorial Sloan Kettering Cancer Center

Memorial Sloan Kettering Cancer Center (MSK or MSKCC) is a cancer treatment and research institution in New York City, founded in 1884 as the New York Cancer Hospital.

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Mothers against decapentaplegic homolog 1

Mothers against decapentaplegic homolog 1 also known as SMAD family member 1 or SMAD1 is a protein that in humans is encoded by the SMAD1 gene.

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Mothers against decapentaplegic homolog 2

Mothers against decapentaplegic homolog 2 also known as SMAD family member 2 or SMAD2 is a protein that in humans is encoded by the SMAD2 gene.

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Mothers against decapentaplegic homolog 3

Mothers against decapentaplegic homolog 3 also known as SMAD family member 3 or SMAD3 is a protein that in humans is encoded by the SMAD3 gene.

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Mothers against decapentaplegic homolog 4

SMAD4, also called SMAD family member 4, Mothers against decapentaplegic homolog 4, or DPC4 (Deleted in Pancreatic Cancer-4) is a highly-conserved protein present in all metazoans.

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NFIX

Nuclear factor 1 X-type is a protein that in humans is encoded by the NFIX gene.

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Oligomer

An oligomer (oligo-, "a few" + -mer, "parts") is a molecular complex of chemicals that consists of a few monomer units, in contrast to a polymer, where the number of monomers is, in principle, infinite.

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P73

p73 is a protein related to the p53 tumor protein.

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Phenylalanine

Phenylalanine (symbol Phe or F) is an α-amino acid with the formula.

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Proline

Proline (symbol Pro or P) is a proteinogenic amino acid that is used in the biosynthesis of proteins.

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Promyelocytic leukemia protein

Promyelocytic leukemia protein (PML) (also known as MYL, RNF71, PP8675 or TRIM19) is the protein product of the PML gene.

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Protein domain

A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain.

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Protein–protein interaction

Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.

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R-SMAD

R-SMADs are receptor-regulated SMADs.

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SKIL

Ski-like protein is a protein that in humans is encoded by the SKIL gene.

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SNW1

SNW domain-containing protein 1 is a protein that in humans is encoded by the SNW1 gene.

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Structural motif

In a chain-like biological molecule, such as a protein or nucleic acid, a structural motif is a supersecondary structure, which also appears in a variety of other molecules.

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TGF beta signaling pathway

The transforming growth factor beta (TGFB) signaling pathway is involved in many cellular processes in both the adult organism and the developing embryo including cell growth, cell differentiation, apoptosis, cellular homeostasis and other cellular functions.

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Transcription coregulator

In molecular biology and genetics, transcription coregulators are proteins that interact with transcription factors to either activate or repress the transcription of specific genes.

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Transforming growth factor beta

Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes four different isoforms (TGF-β 1 to 4, HGNC symbols TGFB1, TGFB2, TGFB3, TGFB4) and many other signaling proteins produced by all white blood cell lineages.

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Zinc finger

A zinc finger is a small protein structural motif that is characterized by the coordination of one or more zinc ions (Zn2+) in order to stabilize the fold.

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Redirects here:

SKI (gene).

References

[1] https://en.wikipedia.org/wiki/SKI_protein

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