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SRD5A1

Index SRD5A1

3-Oxo-5α-steroid 4-dehydrogenase 1 is an enzyme that in humans is encoded by the SRD5A1 gene. [1]

Table of Contents

  1. 23 relations: Adrenocorticotropic hormone, Akt/PKB signaling pathway, Androgen, Androstanedione, Androstenedione, Dihydrotestosterone, Enzyme, Esophagus, ETV4, Gene, Hyperinsulinemia, Isozyme, Liver, Nicotinamide adenine dinucleotide phosphate, Polycystic ovary syndrome, Prostate cancer, Skin, SRD5A2, SRD5A3, Steroidogenic enzyme, Testosterone, Vitamin E, 5α-Reductase.

Adrenocorticotropic hormone

Adrenocorticotropic hormone (ACTH; also adrenocorticotropin, corticotropin) is a polypeptide tropic hormone produced by and secreted by the anterior pituitary gland.

See SRD5A1 and Adrenocorticotropic hormone

Akt/PKB signaling pathway

The Akt signaling pathway or PI3K-Akt signaling pathway is a signal transduction pathway that promotes survival and growth in response to extracellular signals.

See SRD5A1 and Akt/PKB signaling pathway

Androgen

An androgen (from Greek andr-, the stem of the word meaning "man") is any natural or synthetic steroid hormone that regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors.

See SRD5A1 and Androgen

Androstanedione

Androstanedione, also known as 5α-androstanedione or as 5α-androstane-3,17-dione, is a naturally occurring androstane (5α-androstane) steroid and an endogenous metabolite of androgens like testosterone, dihydrotestosterone (DHT), dehydroepiandrosterone (DHEA), and androstenedione.

See SRD5A1 and Androstanedione

Androstenedione

Androstenedione, or 4-androstenedione (abbreviated as A4 or Δ4-dione), also known as androst-4-ene-3,17-dione, is an endogenous weak androgen steroid hormone and intermediate in the biosynthesis of estrone and of testosterone from dehydroepiandrosterone (DHEA).

See SRD5A1 and Androstenedione

Dihydrotestosterone

Dihydrotestosterone (DHT, 5α-dihydrotestosterone, 5α-DHT, androstanolone or stanolone) is an endogenous androgen sex steroid and hormone primarily involved in the growth and repair of the prostate and the penis, as well as the production of sebum and body hair composition.

See SRD5A1 and Dihydrotestosterone

Enzyme

Enzymes are proteins that act as biological catalysts by accelerating chemical reactions.

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Esophagus

The esophagus (American English) or oesophagus (British English, see spelling differences; both;: (o)esophagi or (o)esophaguses), colloquially known also as the food pipe, food tube, or gullet, is an organ in vertebrates through which food passes, aided by peristaltic contractions, from the pharynx to the stomach.

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ETV4

ETS translocation variant 4 (ETV4), also known as polyoma enhancer activator 3 (PEA3), is a member of the PEA3 subfamily of Ets transcription factors.

See SRD5A1 and ETV4

Gene

In biology, the word gene has two meanings.

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Hyperinsulinemia

Hyperinsulinemia is a condition in which there are excess levels of insulin circulating in the blood relative to the level of glucose.

See SRD5A1 and Hyperinsulinemia

Isozyme

In biochemistry, isozymes (also known as isoenzymes or more generally as multiple forms of enzymes) are enzymes that differ in amino acid sequence but catalyze the same chemical reaction.

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Liver

The liver is a major metabolic organ exclusively found in vertebrate animals, which performs many essential biological functions such as detoxification of the organism, and the synthesis of proteins and various other biochemicals necessary for digestion and growth.

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Nicotinamide adenine dinucleotide phosphate

Nicotinamide adenine dinucleotide phosphate, abbreviated NADP or, in older notation, TPN (triphosphopyridine nucleotide), is a cofactor used in anabolic reactions, such as the Calvin cycle and lipid and nucleic acid syntheses, which require NADPH as a reducing agent ('hydrogen source').

See SRD5A1 and Nicotinamide adenine dinucleotide phosphate

Polycystic ovary syndrome

Polycystic ovary syndrome, or polycystic ovarian syndrome (PCOS), is the most common endocrine disorder in women of reproductive age.

See SRD5A1 and Polycystic ovary syndrome

Prostate cancer

Prostate cancer is the uncontrolled growth of cells in the prostate, a gland in the male reproductive system below the bladder.

See SRD5A1 and Prostate cancer

Skin

Skin is the layer of usually soft, flexible outer tissue covering the body of a vertebrate animal, with three main functions: protection, regulation, and sensation.

See SRD5A1 and Skin

SRD5A2

The human gene SRD5A2 encodes the 3-oxo-5α-steroid 4-dehydrogenase 2 enzyme, also known as 5α-reductase type 2 (5αR2), one of three isozymes of 5α-reductase.

See SRD5A1 and SRD5A2

SRD5A3

Steroid 5-alpha-reductase 3, also known as 3-oxo-5-alpha-steroid 4-dehydrogenase 3, is an enzyme that in humans is encoded by the SRD5A3 gene.

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Steroidogenic enzyme

Steroidogenic enzymes are enzymes that are involved in steroidogenesis and steroid biosynthesis.

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Testosterone

Testosterone is the primary male sex hormone and androgen in males.

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Vitamin E

Vitamin E is a group of eight fat soluble compounds that include four tocopherols and four tocotrienols.

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5α-Reductase

5α-Reductases, also known as 3-oxo-5α-steroid 4-dehydrogenases, are enzymes involved in steroid metabolism. SRD5A1 and 5α-Reductase are genes on human chromosome 5.

See SRD5A1 and 5α-Reductase

References

[1] https://en.wikipedia.org/wiki/SRD5A1

Also known as 5α Reductase I, 5α Reductase type 1, 5α Reductase type I, 5α-Reductase I, 5α-Reductase type 1, 5α-Reductase type I, SRD5A1 (gene).