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STAT5A

Index STAT5A

Signal transducer and activator of transcription 5A is a protein that in humans is encoded by the STAT5A gene. [1]

36 relations: Apoptosis, Breast cancer, CBX5 (gene), Chaperone (protein), Chemotherapy, Cisplatin, Colorectal cancer, CRKL, Epidermal growth factor receptor, ERBB4, Erythropoietin receptor, Gene, Head and neck cancer, Homology (biology), JAK-STAT signaling pathway, Janus kinase 1, Janus kinase 2, Leukemia, MAPK1, N-myc-interactor, Phenylalanine, Placentalia, Prolactin, Prostate cancer, Protein, Protein–protein interaction, PTPN11, Serine, SH2 domain, Squamous cell carcinoma, STAT protein, STAT5, STAT5B, Threonine, Transcription factor, Tyrosine.

Apoptosis

Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.

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Breast cancer

Breast cancer is cancer that develops from breast tissue.

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CBX5 (gene)

Chromobox protein homolog 5 is a protein that in humans is encoded by the CBX5 gene.

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Chaperone (protein)

In molecular biology, molecular chaperones are proteins that assist the covalent folding or unfolding and the assembly or disassembly of other macromolecular structures.

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Chemotherapy

Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen.

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Cisplatin

Cisplatin is a chemotherapy medication used to treat a number of cancers.

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Colorectal cancer

Colorectal cancer (CRC), also known as bowel cancer and colon cancer, is the development of cancer from the colon or rectum (parts of the large intestine).

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CRKL

Crk-like protein is a protein that in humans is encoded by the CRKL gene.

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Epidermal growth factor receptor

The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor family (EGF family) of extracellular protein ligands.

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ERBB4

Receptor tyrosine-protein kinase erbB-4 is an enzyme that in humans is encoded by the ERBB4 gene.

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Erythropoietin receptor

The erythropoietin receptor (EpoR) is a protein that in humans is encoded by the EPOR gene.

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Gene

In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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Head and neck cancer

Head and neck cancer is a group of cancers that starts in the mouth, nose, throat, larynx, sinuses, or salivary glands.

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Homology (biology)

In biology, homology is the existence of shared ancestry between a pair of structures, or genes, in different taxa.

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JAK-STAT signaling pathway

The JAK-STAT signalling pathway is a chain of interactions between proteins in a cell, and is involved in processes such as immunity, cell division, cell death and tumour formation.

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Janus kinase 1

JAK1 is a human tyrosine kinase protein essential for signaling for certain type I and type II cytokines.

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Janus kinase 2

Janus kinase 2 (commonly called JAK2) is a non-receptor tyrosine kinase.

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Leukemia

Leukemia, also spelled leukaemia, is a group of cancers that usually begin in the bone marrow and result in high numbers of abnormal white blood cells.

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MAPK1

Mitogen-activated protein kinase 1, also known as MAPK1, p42MAPK, and ERK2, is an enzyme that in humans is encoded by the MAPK1 gene.

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N-myc-interactor

N-myc-interactor also known as N-myc and STAT interactor is a protein that in humans is encoded by the NMI gene.

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Phenylalanine

Phenylalanine (symbol Phe or F) is an α-amino acid with the formula.

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Placentalia

Placentalia ("Placentals") is one of the three extant subdivisions of the class of animals Mammalia; the other two are Monotremata and Marsupialia.

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Prolactin

Prolactin (PRL), also known as luteotropic hormone or luteotropin, is a protein that is best known for its role in enabling mammals, usually females, to produce milk.

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Prostate cancer

Prostate cancer is the development of cancer in the prostate, a gland in the male reproductive system.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Protein–protein interaction

Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.

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PTPN11

Tyrosine-protein phosphatase non-receptor type 11 (PTPN11) also known as protein-tyrosine phosphatase 1D (PTP-1D), SHP-2, or protein-tyrosine phosphatase 2C (PTP-2C) is an enzyme that in humans is encoded by the PTPN11 gene.

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Serine

Serine (symbol Ser or S) is an ɑ-amino acid that is used in the biosynthesis of proteins.

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SH2 domain

The SH2 (Src Homology 2) domain is a structurally conserved protein domain contained within the Src oncoprotein and in many other intracellular signal-transducing proteins.

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Squamous cell carcinoma

Squamous cell carcinomas, also known as epidermoid carcinoma are a number of different types of cancer that result from squamous cells.

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STAT protein

Members of the signal transducer and activator of transcription (STAT) protein family are intracellular transcription factors that mediate many aspects of cellular immunity, proliferation, apoptosis and differentiation.

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STAT5

Signal transducer and activator of transcription 5 (STAT5) refers to two highly related proteins, STAT5A and STAT5B, which are part of the seven-membered STAT family of proteins.

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STAT5B

Signal transducer and activator of transcription 5B is a protein that in humans is encoded by the STAT5B gene.

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Threonine

Threonine (symbol Thr or T) is an amino acid that is used in the biosynthesis of proteins.

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Transcription factor

In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.

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Tyrosine

Tyrosine (symbol Tyr or Y) or 4-hydroxyphenylalanine is one of the 20 standard amino acids that are used by cells to synthesize proteins.

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STAT5A (gene).

References

[1] https://en.wikipedia.org/wiki/STAT5A

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