Faster access than browser!
35 relations: Amino acid, Antibody, Bi-specific T-cell engager, Bispecific monoclonal antibody, Breast cancer, Brolucizumab, C-terminus, Cardiac surgery, Chimeric antigen receptor, Complement component 5, Complement system, Dissociation constant, Escherichia coli, Flow cytometry, Fragment antigen-binding, Fragment crystallizable region, Fusion protein, Glycine, HER2/neu, Hybridoma technology, Immunoglobulin heavy chain, Immunoglobulin light chain, Immunohistochemistry, Ligand (biochemistry), Monoclonal antibody, N-terminus, Peptide, Pexelizumab, Phage display, Protein A, Protein G, Protein L, Serine, Subcloning, Threonine.
Amino acid
Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.
New!!: Single-chain variable fragment and Amino acid · See more »
Antibody
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses.
New!!: Single-chain variable fragment and Antibody · See more »
Bi-specific T-cell engager
Bi-specific T-cell engagers (BiTEs) are a class of artificial bispecific monoclonal antibodies that are investigated for the use as anti-cancer drugs.
New!!: Single-chain variable fragment and Bi-specific T-cell engager · See more »
Bispecific monoclonal antibody
A bispecific monoclonal antibody (BsMAb, BsAb) is an artificial protein that can simultaneously bind to two different types of antigen.
New!!: Single-chain variable fragment and Bispecific monoclonal antibody · See more »
Breast cancer
Breast cancer is cancer that develops from breast tissue.
New!!: Single-chain variable fragment and Breast cancer · See more »
Brolucizumab
Brolucizumab (INN) is a humanized monoclonal antibody designed for the treatment of wet age-related macular degeneration.
New!!: Single-chain variable fragment and Brolucizumab · See more »
C-terminus
The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH).
New!!: Single-chain variable fragment and C-terminus · See more »
Cardiac surgery
Cardiac surgery, or cardiovascular surgery, is surgery on the heart or great vessels performed by cardiac surgeons.
New!!: Single-chain variable fragment and Cardiac surgery · See more »
Chimeric antigen receptor
Chimeric antigen receptors (CARs, also known as chimeric immunoreceptors, chimeric T cell receptors or artificial T cell receptors) are engineered receptors that combine a new specificity with an immune cell to target cancer cells.
New!!: Single-chain variable fragment and Chimeric antigen receptor · See more »
Complement component 5
Complement component 5 is a protein that in humans is encoded by the C5 gene.
New!!: Single-chain variable fragment and Complement component 5 · See more »
Complement system
The complement system is a part of the immune system that enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promotes inflammation, and attacks the pathogen's cell membrane.
New!!: Single-chain variable fragment and Complement system · See more »
Dissociation constant
In chemistry, biochemistry, and pharmacology, a dissociation constant (K_d) is a specific type of equilibrium constant that measures the propensity of a larger object to separate (dissociate) reversibly into smaller components, as when a complex falls apart into its component molecules, or when a salt splits up into its component ions.
New!!: Single-chain variable fragment and Dissociation constant · See more »
Escherichia coli
Escherichia coli (also known as E. coli) is a Gram-negative, facultatively anaerobic, rod-shaped, coliform bacterium of the genus Escherichia that is commonly found in the lower intestine of warm-blooded organisms (endotherms).
New!!: Single-chain variable fragment and Escherichia coli · See more »
Flow cytometry
In biotechnology, flow cytometry is a laser- or impedance-based, biophysical technology employed in cell counting, cell sorting, biomarker detection and protein engineering, by suspending cells in a stream of fluid and passing them through an electronic detection apparatus.
New!!: Single-chain variable fragment and Flow cytometry · See more »
Fragment antigen-binding
The antigen-binding (Fab) fragment is a region on an antibody that binds to antigens.
New!!: Single-chain variable fragment and Fragment antigen-binding · See more »
Fragment crystallizable region
The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system.
New!!: Single-chain variable fragment and Fragment crystallizable region · See more »
Fusion protein
Fusion proteins or chimeric (\kī-ˈmir-ik) proteins (literally, made of parts from different sources) are proteins created through the joining of two or more genes that originally coded for separate proteins.
New!!: Single-chain variable fragment and Fusion protein · See more »
Glycine
Glycine (symbol Gly or G) is the amino acid that has a single hydrogen atom as its side chain.
New!!: Single-chain variable fragment and Glycine · See more »
HER2/neu
Receptor tyrosine-protein kinase erbB-2, also known as CD340 (cluster of differentiation 340), proto-oncogene Neu, Erbb2 (rodent), or ERBB2 (human), is a protein that in humans is encoded by the ERBB2 gene.
New!!: Single-chain variable fragment and HER2/neu · See more »
Hybridoma technology
Hybridoma technology is a method for producing large numbers of identical antibodies (also called monoclonal antibodies).
New!!: Single-chain variable fragment and Hybridoma technology · See more »
Immunoglobulin heavy chain
The immunoglobulin heavy chain (IgH) is the large polypeptide subunit of an antibody (immunoglobulin).
New!!: Single-chain variable fragment and Immunoglobulin heavy chain · See more »
Immunoglobulin light chain
The immunoglobulin light chain is the small polypeptide subunit of an antibody (immunoglobulin).
New!!: Single-chain variable fragment and Immunoglobulin light chain · See more »
Immunohistochemistry
Immunohistochemistry (IHC) involves the process of selectively imaging antigens (proteins) in cells of a tissue section by exploiting the principle of antibodies binding specifically to antigens in biological tissues.
New!!: Single-chain variable fragment and Immunohistochemistry · See more »
Ligand (biochemistry)
In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.
New!!: Single-chain variable fragment and Ligand (biochemistry) · See more »
Monoclonal antibody
Monoclonal antibodies (mAb or moAb) are antibodies that are made by identical immune cells that are all clones of a unique parent cell.
New!!: Single-chain variable fragment and Monoclonal antibody · See more »
N-terminus
The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide referring to the free amine group (-NH2) located at the end of a polypeptide.
New!!: Single-chain variable fragment and N-terminus · See more »
Peptide
Peptides (from Gr.: πεπτός, peptós "digested"; derived from πέσσειν, péssein "to digest") are short chains of amino acid monomers linked by peptide (amide) bonds.
New!!: Single-chain variable fragment and Peptide · See more »
Pexelizumab
Pexelizumab is a drug designed to reduce side effects of coronary artery bypass grafting and angioplasty, among other types of cardiac surgery.
New!!: Single-chain variable fragment and Pexelizumab · See more »
Phage display
Phage display is a laboratory technique for the study of protein–protein, protein–peptide, and protein–DNA interactions that uses bacteriophages (viruses that infect bacteria) to connect proteins with the genetic information that encodes them.
New!!: Single-chain variable fragment and Phage display · See more »
Protein A
Protein A is a 42 kDa surface protein originally found in the cell wall of the bacteria Staphylococcus aureus.
New!!: Single-chain variable fragment and Protein A · See more »
Protein G
Protein G is an immunoglobulin-binding protein expressed in group C and G Streptococcal bacteria much like Protein A but with differing binding specificities.
New!!: Single-chain variable fragment and Protein G · See more »
Protein L
Protein L was first isolated from the surface of bacterial species Peptostreptococcus magnus and was found to bind immunoglobulins through L chain interaction, from which the name was suggested.
New!!: Single-chain variable fragment and Protein L · See more »
Serine
Serine (symbol Ser or S) is an ɑ-amino acid that is used in the biosynthesis of proteins.
New!!: Single-chain variable fragment and Serine · See more »
Subcloning
In molecular biology, subcloning is a technique used to move a particular DNA sequence from a parent vector to a destination vector.
New!!: Single-chain variable fragment and Subcloning · See more »
Threonine
Threonine (symbol Thr or T) is an amino acid that is used in the biosynthesis of proteins.
New!!: Single-chain variable fragment and Threonine · See more »
Redirects here:
Bi-scFv, Di-scFv, Diabody, Fv Fragment, Fv fragment, Fv fragments, ScFv, Single Chain Variable Fragment, Single chain, Single chain Fv, Single chain variable fragment, Single-chain, Single-chain Fv, Tetrabody, Tri-scFv, Triabody, Tribody.
References
[1] https://en.wikipedia.org/wiki/Single-chain_variable_fragment
