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Septic shock

Index Septic shock

Septic shock is a serious medical condition that occurs when sepsis, which is organ injury or damage in response to infection, leads to dangerously low blood pressure and abnormalities in cellular metabolism. [1]

121 relations: Abdomen, Albumin, Angiotensin, Anthrax toxin, Antihypotensive agent, Antimicrobial, Appendicitis, Bacilli, Bacteremia, Bacteria, Beta blocker, Blood culture, Blood gas test, Blood pressure, Bradycardia, Broad-spectrum antibiotic, CD14, Centers for Disease Control and Prevention, Cholera toxin, Coagulation, Cochrane (organisation), Cortisol, Critical Care Medicine (journal), Cytokine, Death, Disseminated intravascular coagulation, Distributive shock, Diverticulitis, Dopamine, Drotrecogin alfa, Early goal-directed therapy, Elsevier, Enterotoxin, Exotoxin, Expert Review of Anti-infective Therapy, Fever, Fluid replacement, Fungus, Gram-negative bacteria, Gram-positive bacteria, Heart arrhythmia, Heart rate, Heat-stable enterotoxin, Hemodynamics, Hemolysin, Hospice, Hospital-acquired infection, Human body temperature, Hydroxyethyl starch, Hypotension, ..., Hypoxia (medical), Idiopathic disease, Immune response, Immune system, Immunodeficiency, Infection, Infectious disease (medical specialty), Innate immune system, Intensive care unit, Interleukin 4, Interleukin 6, Interleukin-1 family, Intravenous therapy, Ischemia, Kidney failure, Lactic acid, Lipopolysaccharide, Lymphocyte antigen 96, Macrophage, McGraw-Hill Education, Mean arterial pressure, Medicine, Meningitis, Mesenteric ischemia, Methicillin-resistant Staphylococcus aureus, Microvessel, Monocyte, Mortality rate, Multiple organ dysfunction syndrome, Necrotizing fasciitis, Neutrophil, NF-κB, Norepinephrine (medication), Pancreatitis, Parasitism, Pathogenic bacteria, PCO2, Perfusion, Phospholipase, Phys.org, Pneumonia, Polymyxin B, Protein C, Pyelonephritis, Recombinant DNA, ResearchGate, Ringer's lactate solution, Saline (medicine), Salmonella, Saunders (imprint), Sepsis, Shiga toxin, Superantigen, Surviving Sepsis Campaign, Systemic inflammatory response syndrome, Tachycardia, Tachypnea, Thrombomodulin, Tissue (biology), Tissue factor pathway inhibitor, TLR4, Tumor necrosis factor alpha, Urinary system, Urinary tract infection, Vascular permeability, Vascular resistance, Vasodilation, Vasopressin, Virus, Volume expander, White blood cell. Expand index (71 more) »

Abdomen

The abdomen (less formally called the belly, stomach, tummy or midriff) constitutes the part of the body between the thorax (chest) and pelvis, in humans and in other vertebrates.

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Albumin

The albumins (formed from Latin: albumen "(egg) white; dried egg white") are a family of globular proteins, the most common of which are the serum albumins.

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Angiotensin

Angiotensin is a peptide hormone that causes vasoconstriction and an increase in blood pressure.

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Anthrax toxin

Anthrax toxin is a three-protein exotoxin secreted by virulent strains of the bacterium, Bacillus anthracis—the causative agent of anthrax.

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Antihypotensive agent

An antihypotensive agent, also known as a vasopressor agent or pressor, is any medication that tends to raise reduced blood pressure.

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Antimicrobial

An antimicrobial is an agent that kills microorganisms or stops their growth.

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Appendicitis

Appendicitis is inflammation of the appendix.

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Bacilli

Bacilli refers to a taxonomic class of bacteria.

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Bacteremia

Bacteremia (also bacteraemia) is the presence of bacteria in the blood.

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Bacteria

Bacteria (common noun bacteria, singular bacterium) is a type of biological cell.

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Beta blocker

Beta blockers, also written β-blockers, are a class of medications that are particularly used to manage abnormal heart rhythms, and to protect the heart from a second heart attack (myocardial infarction) after a first heart attack (secondary prevention).

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Blood culture

Blood culture is a microbiological culture of blood.

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Blood gas test

A blood gas test or blood gas analysis tests blood to measure blood gas tension values, it also measures blood pH, and the level and base excess of bicarbonate.

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Blood pressure

Blood pressure (BP) is the pressure of circulating blood on the walls of blood vessels.

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Bradycardia

Bradycardia is a condition wherein an individual has a very slow heart rate, typically defined as a resting heart rate of under 60 beats per minute (BPM) in adults.

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Broad-spectrum antibiotic

The term broad-spectrum antibiotic can refer to an antibiotic that acts on the two major bacterial groups, gram-positive and gram-negative, or any antibiotic that acts against a wide range of disease-causing bacteria.

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CD14

CD14 (cluster of differentiation 14) is a human gene.

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Centers for Disease Control and Prevention

The Centers for Disease Control and Prevention (CDC) is the leading national public health institute of the United States.

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Cholera toxin

Cholera toxin (also known as choleragen and sometimes abbreviated to CTX, Ctx or CT) is protein complex secreted by the bacterium Vibrio cholerae.

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Coagulation

Coagulation (also known as clotting) is the process by which blood changes from a liquid to a gel, forming a blood clot.

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Cochrane (organisation)

Cochrane is a non-profit, non-governmental organization formed to organize medical research findings so as to facilitate evidence-based choices about health interventions faced by health professionals, patients, and policy makers.

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Cortisol

Cortisol is a steroid hormone, in the glucocorticoid class of hormones.

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Critical Care Medicine (journal)

Critical Care Medicine is a peer-reviewed monthly medical journal in the field of intensive-care medicine.

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Cytokine

Cytokines are a broad and loose category of small proteins (~5–20 kDa) that are important in cell signaling.

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Death

Death is the cessation of all biological functions that sustain a living organism.

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Disseminated intravascular coagulation

Disseminated intravascular coagulation (DIC) is a condition in which blood clots form throughout the body, blocking small blood vessels.

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Distributive shock

Distributive shock is a medical condition in which abnormal distribution of blood flow in the smallest blood vessels results in inadequate supply of blood to the body's tissues and organs.

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Diverticulitis

Diverticulitis, specifically colonic diverticulitis, is a gastrointestinal disease characterized by inflammation of abnormal pouches - diverticuli - which can develop in the wall of the large intestine.

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Dopamine

Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is an organic chemical of the catecholamine and phenethylamine families that plays several important roles in the brain and body.

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Drotrecogin alfa

Drotrecogin alfa (activated) (Xigris, marketed by Eli Lilly and Company) is a recombinant form of human activated protein C that has anti-thrombotic, anti-inflammatory, and profibrinolytic properties.

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Early goal-directed therapy

Early goal-directed therapy was introduced by Emanuel P. Rivers in The New England Journal of Medicine in 2001 and is a technique used in critical care medicine involving intensive monitoring and aggressive management of perioperative hemodynamics in patients with a high risk of morbidity and mortality.

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Elsevier

Elsevier is an information and analytics company and one of the world's major providers of scientific, technical, and medical information.

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Enterotoxin

An enterotoxin is a protein exotoxin released by a microorganism that targets the intestines.

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Exotoxin

An exotoxin is a toxin secreted by bacteria.

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Expert Review of Anti-infective Therapy

Expert Review of Anti-infective Therapy is a monthly peer-reviewed medical journal publishing review articles and original papers on all aspects of anti-infective therapy.

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Fever

Fever, also known as pyrexia and febrile response, is defined as having a temperature above the normal range due to an increase in the body's temperature set-point.

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Fluid replacement

Fluid replacement or fluid resuscitation is the medical practice of replenishing bodily fluid lost through sweating, bleeding, fluid shifts or other pathologic processes.

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Fungus

A fungus (plural: fungi or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms.

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Gram-negative bacteria

Gram-negative bacteria are bacteria that do not retain the crystal violet stain used in the gram-staining method of bacterial differentiation.

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Gram-positive bacteria

Gram-positive bacteria are bacteria that give a positive result in the Gram stain test, which is traditionally used to quickly classify bacteria into two broad categories according to their cell wall.

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Heart arrhythmia

Heart arrhythmia (also known as arrhythmia, dysrhythmia, or irregular heartbeat) is a group of conditions in which the heartbeat is irregular, too fast, or too slow.

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Heart rate

Heart rate is the speed of the heartbeat measured by the number of contractions of the heart per minute (bpm).

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Heat-stable enterotoxin

Heat-stable enterotoxins (STs) are secretory peptides produced by some bacterial strains, such as enterotoxigenic ''Escherichia coli'' which are in general toxic to animals.

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Hemodynamics

Hemodynamics or hæmodynamics is the dynamics of blood flow.

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Hemolysin

Hemolysins or haemolysins are lipids and proteins that cause lysis of red blood cells by destroying their cell membrane.

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Hospice

Hospice care is a type of care and philosophy of care that focuses on the palliation of a chronically ill, terminally ill or seriously ill patient's pain and symptoms, and attending to their emotional and spiritual needs.

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Hospital-acquired infection

A hospital-acquired infection (HAI), also known as a nosocomial infection, is an infection that is acquired in a hospital or other health care facility.

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Human body temperature

Normal human body temperature, also known as normothermia or euthermia, is the typical temperature range found in humans.

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Hydroxyethyl starch

Hydroxyethyl starch (HES/HAES), sold under the brand name Voluven among others, is a nonionic starch derivative, used as a volume expander in intravenous therapy.

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Hypotension

Hypotension is low blood pressure, especially in the arteries of the systemic circulation.

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Hypoxia (medical)

Hypoxia is a condition in which the body or a region of the body is deprived of adequate oxygen supply at the tissue level.

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Idiopathic disease

An idiopathic disease is any disease with an unknown cause or mechanism of apparently spontaneous origin.

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Immune response

The Immune response is the body's response caused by its immune system being activated by antigens.

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Immune system

The immune system is a host defense system comprising many biological structures and processes within an organism that protects against disease.

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Immunodeficiency

Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent.

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Infection

Infection is the invasion of an organism's body tissues by disease-causing agents, their multiplication, and the reaction of host tissues to the infectious agents and the toxins they produce.

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Infectious disease (medical specialty)

Infectious disease, also known as infectious diseases, infectious medicine, infectious disease medicine or infectiology, is a medical specialty dealing with the diagnosis, control and treatment of infections.

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Innate immune system

The innate immune system, also known as the non-specific immune system or in-born immunity system, is an important subsystem of the overall immune system that comprises the cells and mechanisms involved in the defense of the host from infection by other organisms.

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Intensive care unit

Intensive care unit An intensive care unit (ICU), also known as an intensive therapy unit or intensive treatment unit (ITU) or critical care unit (CCU), is a special department of a hospital or health care facility that provides intensive treatment medicine.

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Interleukin 4

The interleukin 4 (IL4, IL-4) is a cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells.

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Interleukin 6

Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine.

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Interleukin-1 family

The Interleukin-1 family (IL-1 family) is a group of 11 cytokines that plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults.

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Intravenous therapy

Intravenous therapy (IV) is a therapy that delivers liquid substances directly into a vein (intra- + ven- + -ous).

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Ischemia

Ischemia or ischaemia is a restriction in blood supply to tissues, causing a shortage of oxygen that is needed for cellular metabolism (to keep tissue alive).

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Kidney failure

Kidney failure, also known as end-stage kidney disease, is a medical condition in which the kidneys no longer work.

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Lactic acid

Lactic acid is an organic compound with the formula CH3CH(OH)COOH.

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Lipopolysaccharide

Lipopolysaccharides (LPS), also known as lipoglycans and endotoxins, are large molecules consisting of a lipid and a polysaccharide composed of O-antigen, outer core and inner core joined by a covalent bond; they are found in the outer membrane of Gram-negative bacteria.

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Lymphocyte antigen 96

Lymphocyte antigen 96, also known as "MD2," is a protein that in humans is encoded by the LY96 gene.

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Macrophage

Macrophages (big eaters, from Greek μακρός (makrós).

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McGraw-Hill Education

McGraw-Hill Education (MHE) is a learning science company and one of the "big three" educational publishers that provides customized educational content, software, and services for pre-K through postgraduate education.

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Mean arterial pressure

In medicine, the mean arterial pressure (MAP) is an average blood pressure in an individual during a single cardiac cycle.

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Medicine

Medicine is the science and practice of the diagnosis, treatment, and prevention of disease.

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Meningitis

Meningitis is an acute inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges.

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Mesenteric ischemia

Mesenteric ischemia is a medical condition in which injury of the small intestine occurs due to not enough blood supply.

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Methicillin-resistant Staphylococcus aureus

Methicillin-resistant Staphylococcus aureus (MRSA) refers to a group of gram-positive bacteria that are genetically distinct from other strains of Staphylococcus aureus.

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Microvessel

Microvessel or microvasculature refers to the smallest systems of blood vessels in a body, including those responsible for microcirculation, the system of smaller blood vessels that distribute blood within tissues.

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Monocyte

Monocytes are a type of leukocyte, or white blood cell.

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Mortality rate

Mortality rate, or death rate, is a measure of the number of deaths (in general, or due to a specific cause) in a particular population, scaled to the size of that population, per unit of time.

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Multiple organ dysfunction syndrome

Multiple organ dysfunction syndrome (MODS), also known as multiple organ failure (MOF), total organ failure (TOF) or multisystem organ failure (MSOF), is altered organ function in an acutely ill patient requiring medical intervention to achieve homeostasis.

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Necrotizing fasciitis

Necrotizing fasciitis (NF), commonly known as flesh-eating disease, is an infection that results in the death of the body's soft tissue.

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Neutrophil

Neutrophils (also known as neutrocytes) are the most abundant type of granulocytes and the most abundant (40% to 70%) type of white blood cells in most mammals.

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NF-κB

NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival.

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Norepinephrine (medication)

Norepinephrine, also known as noradrenaline, is a medication used to treat people with very low blood pressure.

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Pancreatitis

Pancreatitis is inflammation of the pancreas.

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Parasitism

In evolutionary biology, parasitism is a relationship between species, where one organism, the parasite, lives on or in another organism, the host, causing it some harm, and is adapted structurally to this way of life.

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Pathogenic bacteria

Pathogenic bacteria are bacteria that can cause disease.

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PCO2

The pCO2, PCO2, p_\ceor P_\ce is the partial pressure of carbon dioxide (CO2), often used in reference to blood, but also used in oceanography to describe the partial pressure of CO2 in the Ocean, and in life support systems engineering and underwater diving to describe the partial pressure in a breathing gas.

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Perfusion

Perfusion is the passage of fluid through the circulatory system or lymphatic system to an organ or a tissue, usually referring to the delivery of blood to a capillary bed in tissue.

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Phospholipase

A phospholipase is an enzyme that hydrolyzes phospholipids into fatty acids and other lipophilic substances.

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Phys.org

Phys.org is a science, research and technology news aggregator where much of the content is republished directly from press releases and news agencies-in a practice known as churnalism.

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Pneumonia

Pneumonia is an inflammatory condition of the lung affecting primarily the small air sacs known as alveoli.

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Polymyxin B

Polymyxin B is an antibiotic primarily used for resistant Gram-negative infections.

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Protein C

Protein C, also known as autoprothrombin IIA and blood coagulation factor XIV, is a zymogen, the activated form of which plays an important role in regulating anticoagulation, inflammation, cell death, and maintaining the permeability of blood vessel walls in humans and other animals.

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Pyelonephritis

Pyelonephritis is inflammation of the kidney, typically due to a bacterial infection.

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Recombinant DNA

Recombinant DNA (rDNA) molecules are DNA molecules formed by laboratory methods of genetic recombination (such as molecular cloning) to bring together genetic material from multiple sources, creating sequences that would not otherwise be found in the genome.

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ResearchGate

ResearchGate is a social networking site for scientists and researchers to share papers, ask and answer questions, and find collaborators.

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Ringer's lactate solution

Ringer's lactate solution (RL), also known as sodium lactate solution and Hartmann's solution, is a mixture of sodium chloride, sodium lactate, potassium chloride, and calcium chloride in water.

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Saline (medicine)

Saline, also known as saline solution, is a mixture of sodium chloride in water and has a number of uses in medicine.

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Salmonella

Salmonella is a genus of rod-shaped (bacillus) Gram-negative bacteria of the family Enterobacteriaceae.

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Saunders (imprint)

Saunders is an academic publisher based in the United States.

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Sepsis

Sepsis is a life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs.

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Shiga toxin

Shiga toxins are a family of related toxins with two major groups, Stx1 and Stx2, expressed by genes considered to be part of the genome of lambdoid prophages.

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Superantigen

Superantigens (SAgs) are a class of antigens that cause non-specific activation of T-cells resulting in polyclonal T cell activation and massive cytokine release.

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Surviving Sepsis Campaign

The Surviving Sepsis Campaign (SSC) is a global initiative to bring together professional organizations in reducing mortality from sepsis.

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Systemic inflammatory response syndrome

Systemic inflammatory response syndrome (SIRS) is an inflammatory state affecting the whole body.

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Tachycardia

Tachycardia, also called tachyarrhythmia, is a heart rate that exceeds the normal resting rate.

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Tachypnea

Tachypnea or tachypnoea is abnormally rapid breathing.

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Thrombomodulin

Thrombomodulin (TM), CD141 or BDCA-3 is an integral membrane protein expressed on the surface of endothelial cells and serves as a cofactor for thrombin.

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Tissue (biology)

In biology, tissue is a cellular organizational level between cells and a complete organ.

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Tissue factor pathway inhibitor

Tissue factor pathway inhibitor (or TFPI) is a single-chain polypeptide which can reversibly inhibit Factor Xa (Xa).

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TLR4

Toll-like receptor 4 is a protein that in humans is encoded by the TLR4 gene.

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Tumor necrosis factor alpha

Tumor necrosis factor (TNF, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction.

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Urinary system

The urinary system, also known as the renal system or urinary tract, consists of the kidneys, ureters, bladder, and the urethra.

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Urinary tract infection

A urinary tract infection (UTI) is an infection that affects part of the urinary tract.

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Vascular permeability

Vascular permeability, often in the form of capillary permeability or microvascular permeability, characterizes the capacity of a blood vessel wall to allow for the flow of small molecules (drugs, nutrients, water, ions) or even whole cells (lymphocytes on their way to the site of inflammation) in and out of the vessel.

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Vascular resistance

Vascular resistance is the resistance that must be overcome to push blood through the circulatory system and create flow.

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Vasodilation

Vasodilation is the widening of blood vessels.

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Vasopressin

Vasopressin, also named antidiuretic hormone (ADH), arginine vasopressin (AVP) or argipressin, is a hormone synthesized as a peptide prohormone in neurons in the hypothalamus, and is converted to AVP.

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Virus

A virus is a small infectious agent that replicates only inside the living cells of other organisms.

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Volume expander

A volume expander is a type of intravenous therapy that has the function of providing volume for the circulatory system.

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White blood cell

White blood cells (WBCs), also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.

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Redirects here:

Compensatory anti-inflammatory response syndrome, OVERS, Septic Shock, Septic shock or septicemia, Shock, septic.

References

[1] https://en.wikipedia.org/wiki/Septic_shock

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