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Serine (symbol Ser or S) is an ɑ-amino acid that is used in the biosynthesis of proteins. [1]

76 relations: Acetylcholinesterase, Agonist, Alzheimer's disease, Amine, Amino acid, Amyotrophic lateral sclerosis, Aspartic acid, Biosynthesis, Carboxylic acid, Cerebrospinal fluid, Chemical polarity, Cholinesterase, Chymotrypsin, Cysteine, Deprotonation, Diabetes mellitus, Enantiomer, Enzyme, Escherichia coli, Essential amino acid, Eukaryote, Folate, Genetic code, Glutamic acid, Glycine, Glycine cleavage system, Glycolysis, Glycosylation, Hydroxy group, Insecticide, International Working Group on Neurotransmitter Related Disorders, Isoserine, Journal of Inherited Metabolic Disease, Kinase, Latin, Metabolism, Metabolite, Methyl acrylate, Molecular Genetics and Metabolism, Nerve agent, Nicotinamide adenine dinucleotide, NMDA receptor, Organic Syntheses, Phosphoglycerate dehydrogenase, Phosphohydroxypyruvic acid, Phosphorylation, Phosphoserine, Phosphoserine phosphatase, Phosphoserine transaminase, Proteinogenic amino acid, ..., Protonation, Purine, Pyridoxal phosphate, Pyrimidine, Redox, Reductive amination, Sarcosine, Serine hydroxymethyltransferase, Serine octamer cluster, Serine protease, Serine racemase, Side chain, Signal transduction, Silk, Sphingolipid, ST motif, ST staple, ST turn, Stereoisomerism, Tetrahydrofolic acid, Trypsin, Tryptophan, Ullmann's Encyclopedia of Industrial Chemistry, Umami, 3-Phosphoglyceric acid, 5,10-Methylenetetrahydrofolate. Expand index (26 more) »

Acetylcholinesterase

Acetylcholinesterase, encoded by HGNC gene ACHE; EC 3.1.1.7) is the primary cholinesterase in the body. It is an enzyme that catalyzes the breakdown of acetylcholine and of some other choline esters that function as neurotransmitters. AChE is found at mainly neuromuscular junctions and in chemical synapses of the cholinergic type, where its activity serves to terminate synaptic transmission. It belongs to carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides.

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Agonist

An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.

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Alzheimer's disease

Alzheimer's disease (AD), also referred to simply as Alzheimer's, is a chronic neurodegenerative disease that usually starts slowly and worsens over time.

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Amine

In organic chemistry, amines are compounds and functional groups that contain a basic nitrogen atom with a lone pair.

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Amino acid

Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.

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Amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS), also known as motor neurone disease (MND), and Lou Gehrig's disease, is a specific disease which causes the death of neurons controlling voluntary muscles.

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Aspartic acid

Aspartic acid (symbol Asp or D; salts known as aspartates), is an α-amino acid that is used in the biosynthesis of proteins.

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Biosynthesis

Biosynthesis (also called anabolism) is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms.

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Carboxylic acid

A carboxylic acid is an organic compound that contains a carboxyl group (C(.

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Cerebrospinal fluid

Cerebrospinal fluid (CSF) is a clear, colorless body fluid found in the brain and spinal cord.

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Chemical polarity

In chemistry, polarity is a separation of electric charge leading to a molecule or its chemical groups having an electric dipole or multipole moment.

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Cholinesterase

In biochemistry, a cholinesterase or choline esterase is an esterase that lyses choline-based esters, several of which serve as neurotransmitters.

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Christmas

Christmas is an annual festival commemorating the birth of Jesus Christ,Martindale, Cyril Charles.

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Christmas and holiday season

The Christmas season, also called the festive season, or the holiday season (mainly in the U.S. and Canada; often simply called the holidays),, is an annually recurring period recognized in many Western and Western-influenced countries that is generally considered to run from late November to early January.

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Christmas Eve

Christmas Eve is the evening or entire day before Christmas Day, the festival commemorating the birth of Jesus.

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Christmas traditions

Christmas traditions vary from country to country.

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Chymotrypsin

Chymotrypsin (chymotrypsins A and B, alpha-chymar ophth, avazyme, chymar, chymotest, enzeon, quimar, quimotrase, alpha-chymar, alpha-chymotrypsin A, alpha-chymotrypsin) is a digestive enzyme component of pancreatic juice acting in the duodenum, where it performs proteolysis, the breakdown of proteins and polypeptides.

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Cysteine

Cysteine (symbol Cys or C) is a semi-essential proteinogenic amino acid with the formula HO2CCH(NH2)CH2SH.

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Deprotonation

Deprotonation is the removal (transfer) of a proton (a hydrogen cation, H+) from a Brønsted–Lowry acid in an acid-base reaction.

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Diabetes mellitus

Diabetes mellitus (DM), commonly referred to as diabetes, is a group of metabolic disorders in which there are high blood sugar levels over a prolonged period.

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Enantiomer

In chemistry, an enantiomer, also known as an optical isomer (and archaically termed antipode or optical antipode), is one of two stereoisomers that are mirror images of each other that are non-superposable (not identical), much as one's left and right hands are the same except for being reversed along one axis (the hands cannot be made to appear identical simply by reorientation).

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Enzyme

Enzymes are macromolecular biological catalysts.

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Escherichia coli

Escherichia coli (also known as E. coli) is a Gram-negative, facultatively anaerobic, rod-shaped, coliform bacterium of the genus Escherichia that is commonly found in the lower intestine of warm-blooded organisms (endotherms).

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Essential amino acid

An essential amino acid, or indispensable amino acid, is an amino acid that cannot be synthesized ''de novo'' (from scratch) by the organism, and thus must be supplied in its diet.

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Eukaryote

Eukaryotes are organisms whose cells have a nucleus enclosed within membranes, unlike Prokaryotes (Bacteria and other Archaea).

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Folate

Folate, distinct forms of which are known as folic acid, folacin, and vitamin B9, is one of the B vitamins.

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Genetic code

The genetic code is the set of rules used by living cells to translate information encoded within genetic material (DNA or mRNA sequences) into proteins.

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Glutamic acid

Glutamic acid (symbol Glu or E) is an α-amino acid with formula.

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Glycine

Glycine (symbol Gly or G) is the amino acid that has a single hydrogen atom as its side chain.

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Glycine cleavage system

The glycine cleavage system (GCS) is also known as the glycine decarboxylase complex or GDC.

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Glycolysis

Glycolysis (from glycose, an older term for glucose + -lysis degradation) is the metabolic pathway that converts glucose C6H12O6, into pyruvate, CH3COCOO− + H+.

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Glycosylation

Glycosylation (see also chemical glycosylation) is the reaction in which a carbohydrate, i.e. a glycosyl donor, is attached to a hydroxyl or other functional group of another molecule (a glycosyl acceptor).

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Hydroxy group

A hydroxy or hydroxyl group is the entity with the formula OH.

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Insecticide

Insecticides are substances used to kill insects.

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International Working Group on Neurotransmitter Related Disorders

The International Working Group on Neurotransmitter Related Disorders is an international collaboration of researchers studying neurotransmitter disorders.

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Isoserine

Isoserine is a non-proteinogenic α-hydroxy-β-amino acid, and an isomer of serine.

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Journal of Inherited Metabolic Disease

The Journal of Inherited Metabolic Disease is a peer-reviewed medical journal covering inherited metabolic disorders.

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Kinase

In biochemistry, a kinase is an enzyme that catalyzes the transfer of phosphate groups from high-energy, phosphate-donating molecules to specific substrates.

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Latin

Latin (Latin: lingua latīna) is a classical language belonging to the Italic branch of the Indo-European languages.

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Metabolism

Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical transformations within the cells of organisms.

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Metabolite

A metabolite is the intermediate end product of metabolism.

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Methyl acrylate

Methyl acrylate is an organic compound, more accurately the methyl ester of acrylic acid.

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Molecular Genetics and Metabolism

Molecular Genetics and Metabolism is a peer-reviewed academic journal published by Academic Press.

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Nerve agent

Nerve agents, sometimes also called nerve gases, are a class of organic chemicals that disrupt the mechanisms by which nerves transfer messages to organs.

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New Year

New Year is the time or day at which a new calendar year begins and the calendar's year count increments by one.

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New Year's Day

New Year's Day, also called simply New Year's or New Year, is observed on January 1, the first day of the year on the modern Gregorian calendar as well as the Julian calendar.

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New Year's Eve

In the Gregorian calendar, New Year's Eve (also known as Old Year's Day or Saint Sylvester's Day in many countries), the last day of the year, is on 31 December which is the seventh day of Christmastide.

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Nicotinamide adenine dinucleotide

Nicotinamide adenine dinucleotide (NAD) is a coenzyme found in all living cells.

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NMDA receptor

The N-methyl-D-aspartate receptor (also known as the NMDA receptor or NMDAR), is a glutamate receptor and ion channel protein found in nerve cells.

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Organic Syntheses

Organic Syntheses is a peer-reviewed scientific journal that was established in 1921.

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Phosphoglycerate dehydrogenase

In enzymology, D-3-phosphoglycerate dehydrogenase (PHGDH) is an enzyme that primarily catalyzes the chemical reactions Thus, in the first case, the two substrates of this enzyme are 3-phospho-D-glycerate and NAD+, whereas its 3 products are 3-phosphohydroxypyruvate, NADH, and H+; in the second case, the two substrates of this enzyme are 2-hydroxyglutarate and NAD+, whereas its 3 products are 2-oxoglutarate, NADH, and H+.

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Phosphohydroxypyruvic acid

Phosphohydroxypyruvic acid is an intermediate in the synthesis of serine.

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Phosphorylation

In chemistry, phosphorylation of a molecule is the attachment of a phosphoryl group.

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Phosphoserine

Phosphoserine (abbreviated as SEP or J) is an ester of serine and phosphoric acid.

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Phosphoserine phosphatase

In enzymology, a phosphoserine phosphatase is an enzyme that catalyzes the chemical reaction The 3 substrates of this enzyme are O-phospho-L-serine, O-phospho-D-serine, and H2O, whereas its 3 products are L-serine, D-serine, and phosphate.

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Phosphoserine transaminase

Phosphoserine transaminase (PSAT, phosphoserine aminotransferase, 3-phosphoserine aminotransferase, hydroxypyruvic phosphate-glutamic transaminase, L-phosphoserine aminotransferase, phosphohydroxypyruvate transaminase, phosphohydroxypyruvic-glutamic transaminase, 3-O-phospho-L-serine:2-oxoglutarate aminotransferase, SerC, PdxC, 3PHP transaminase) is an enzyme with systematic name O-phospho-L-serine:2-oxoglutarate aminotransferase.

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Proteinogenic amino acid

Proteinogenic amino acids are amino acids that are incorporated biosynthetically into proteins during translation.

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Protonation

In chemistry, protonation is the addition of a proton (H+) to an atom, molecule, or ion, forming the conjugate acid.

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Purine

A purine is a heterocyclic aromatic organic compound that consists of a pyrimidine ring fused to an imidazole ring.

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Pyridoxal phosphate

Pyridoxal phosphate (PLP, pyridoxal 5'-phosphate, P5P), the active form of vitamin B6, is a coenzyme in a variety of enzymatic reactions.

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Pyrimidine

Pyrimidine is an aromatic heterocyclic organic compound similar to pyridine.

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Redox

Redox (short for reduction–oxidation reaction) (pronunciation: or) is a chemical reaction in which the oxidation states of atoms are changed.

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Reductive amination

Reductive amination (also known as reductive alkylation) is a form of amination that involves the conversion of a carbonyl group to an amine via an intermediate imine.

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Sarcosine

Sarcosine, also known as N-methylglycine, is an intermediate and byproduct in glycine synthesis and degradation.

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Serine hydroxymethyltransferase

Serine hydroxymethyltransferase (SHMT) is a Pyridoxal phosphate (PLP) (Vitamin B6) dependent enzyme which plays an important role in cellular one-carbon pathways by catalyzing the reversible, simultaneous conversions of L-serine to glycine and tetrahydrofolate (THF) to 5,10-methylenetetrahydrofolate (5,10-CH2-THF).

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Serine octamer cluster

The Serine octamer cluster in physical chemistry is an unusually stable cluster consisting of eight serine molecules (Ser) implicated in the origin of homochirality.

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Serine protease

Serine proteases (or serine endopeptidases) are enzymes that cleave peptide bonds in proteins, in which serine serves as the nucleophilic amino acid at the (enzyme's) active site.

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Serine racemase

Serine racemase is an enzyme which generates D-serine from L-serine.

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Side chain

In organic chemistry and biochemistry, a side chain is a chemical group that is attached to a core part of the molecule called "main chain" or backbone.

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Signal transduction

Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular response.

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Silk

Silk is a natural protein fiber, some forms of which can be woven into textiles.

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Sphingolipid

Sphingolipids are a class of lipids containing a backbone of sphingoid bases, a set of aliphatic amino alcohols that includes sphingosine.

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ST motif

The ST motif is a commonly occurring feature in proteins and polypeptides.

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ST staple

The ST staple is a common four- or five-amino acid residue motif in proteins and polypeptides with serine or threonine as the C-terminal residue.

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ST turn

The ST turn is a structural feature in proteins and polypeptides.

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Stereoisomerism

In stereochemistry, stereoisomers are isomeric molecules that have the same molecular formula and sequence of bonded atoms (constitution), but differ in the three-dimensional orientations of their atoms in space.

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Tetrahydrofolic acid

Tetrahydrofolic acid, or tetrahydrofolate, is a folic acid derivative.

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Trypsin

Trypsin is a serine protease from the PA clan superfamily, found in the digestive system of many vertebrates, where it hydrolyzes proteins.

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Tryptophan

Tryptophan (symbol Trp or W) is an α-amino acid that is used in the biosynthesis of proteins.

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Ullmann's Encyclopedia of Industrial Chemistry

Ullmann's Encyclopedia of Industrial Chemistry is a reference work related to industrial chemistry published in English and German.

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Umami

Umami, or savory taste, is one of the five basic tastes (together with sweetness, sourness, bitterness, and saltiness).

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2018

2018 has been designated as the third International Year of the Reef by the International Coral Reef Initiative.

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2019

2019 (MMXIX) will be a common year starting on Tuesday of the Gregorian calendar, the 2019th year of the Common Era (CE) and Anno Domini (AD) designations, the 19th year of the 3rd millennium, the 19th year of the 21st century, and the 10th and last year of the 2010s decade.

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3-Phosphoglyceric acid

3-Phosphoglyceric acid (3PG) is the conjugate acid of glycerate 3-phosphate (GP).

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5,10-Methylenetetrahydrofolate

5,10-Methylenetetrahydrofolate (N5,N10-Methylenetetrahydrofolate; 5,10-CH2-THF) is the substrate used by the enzyme methylenetetrahydrofolate reductase (MTHFR) to generate 5-methyltetrahydrofolate (5-MTHF, or levomefolic acid).

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Redirects here:

2-amino-3-hydroxypropanoic acid, Alternaria serine proteinase, Arthrobacter serine proteinase, D-Serine, D-serine, L-Serine, L-serine, Microbial serine proteases, Serine metabolism.

References

[1] https://en.wikipedia.org/wiki/Serine

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