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Serotonin releasing agent

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A serotonin releasing agent (SRA) is a type of drug that induces the release of serotonin into the neuronal synaptic cleft. [1]

74 relations: Agonist, Alpha-Ethyltryptamine, Alpha-Methyltryptamine, Amiflamine, Aminorex, Anorectic, Antidepressant, Anxiolytic, Bufotenin, Carbamazepine, Cardiac fibrosis, Chemical synapse, Chlorphentermine, Cloforex, Designer drug, Dexfenfluramine, Diethyltryptamine, Diisopropyltryptamine, Dipropyltryptamine, EDMA, Empathogen–entactogen, Enantiomer, Ethyltrifluoromethylaminoindane, Etolorex, Fenfluramine, Flucetorex, Indeloxazine, Levofenfluramine, MBDB, MDAI, MDAT, MDMA, MDMAI, MDMAT, Methylenedioxyamphetamine, MMAI, Monoamine neurotransmitter, Monoamine oxidase inhibitor, Monoamine releasing agent, N,N-Dimethyltryptamine, Neuroprotection, Neurotransmitter, Nootropic, Para-Methoxy-N-ethylamphetamine, Para-Methoxy-N-methylamphetamine, Para-Methoxyamphetamine, Prodrug, Psilocin, Recreational drug use, Selective serotonin reuptake inhibitor, ..., Serotonergic psychedelic, Serotonin, Serotonin receptor agonist, Serotonin reuptake inhibitor, Serotonin-norepinephrine-dopamine releasing agent, Substituted amphetamine, Substituted methylenedioxyphenethylamine, Substituted tryptamine, Trifluoromethylaminoindane, Viqualine, 2-Methyl-MDA, 3,4-Methylenedioxy-N-ethylamphetamine, 3-Methoxy-4-methylamphetamine, 4-Methylaminorex, 4-Methylthioamphetamine, 5-APDB, 5-APDI, 5-HT receptor, 5-HT2 receptor, 5-HT2B receptor, 5-MAPDI, 5-Methyl-MDA, 6-APT, 6-CAT. Expand index (24 more) »

Agonist

An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.

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Alpha-Ethyltryptamine

α-Ethyltryptamine (αET, AET), also known as etryptamine (INN, BAN, USAN), is a psychedelic, stimulant, and entactogenic drug of the tryptamine class.

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Alpha-Methyltryptamine

α-Methyltryptamine (abbreviated as αMT, AMT) is a psychedelic, stimulant, and entactogen drug of the tryptamine class.

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Amiflamine

Amiflamine (FLA-336) is a reversible inhibitor of monoamine oxidase A (MAO-A), thereby being a RIMA, and, to a lesser extent, semicarbazide-sensitive amine oxidase (SSAO), as well as a serotonin releasing agent (SRA).

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Aminorex

Aminorex (Menocil, Apiquel, aminoxaphen, aminoxafen, McN-742) is a weight loss (anorectic) stimulant drug.

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Anorectic

An anorectic or anorexic is a drug which reduces appetite, resulting in lower food consumption, leading to weight loss.

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Antidepressant

Antidepressants are drugs used for the treatment of major depressive disorder and other conditions, including dysthymia, anxiety disorders, obsessive–compulsive disorder, eating disorders, chronic pain, neuropathic pain and, in some cases, dysmenorrhoea, snoring, migraine, attention-deficit hyperactivity disorder (ADHD), addiction, dependence, and sleep disorders.

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Anxiolytic

An anxiolytic (also antipanic or antianxiety agent) is a medication or other intervention that inhibits anxiety.

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Bufotenin

Bufotenin (5-HO-DMT, bufotenine) is a tryptamine related to the neurotransmitter serotonin.

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Carbamazepine

Carbamazepine (CBZ), sold under the tradename Tegretol, among others, is a medication used primarily in the treatment of epilepsy and neuropathic pain.

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Cardiac fibrosis

Cardiac fibrosis may refer to an abnormal thickening of the heart valves due to inappropriate proliferation of cardiac fibroblasts but more commonly refers to the excess deposition of extracellular matrix in the cardiac muscle.

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Chemical synapse

Chemical synapses are biological junctions through which neurons' signals can be exchanged to each other and to non-neuronal cells such as those in muscles or glands.

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Chlorphentermine

Chlorphentermine (trade names Apsedon, Desopimon, Lucofen) is a serotonergic appetite suppressant of the amphetamine family.

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Cloforex

Cloforex (Oberex) is an anorectic of the amphetamine class.

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Designer drug

A designer drug is a structural or functional analog of a controlled substance that has been designed to mimic the pharmacological effects of the original drug, while avoiding classification as illegal and/or detection in standard drug tests.

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Dexfenfluramine

Dexfenfluramine, marketed as dexfenfluramine hydrochloride under the name Redux, is a serotonergic anorectic drug: it reduces appetite by increasing the amount of extracellular serotonin in the brain.

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Diethyltryptamine

DET, also known under its chemical name N,N-diethyltryptamine and as T-9, is a psychedelic drug closely related to DMT and 4-HO-DET.

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Diisopropyltryptamine

Diisopropyltryptamine (also known as N,N-diisopropyltryptamine or DiPT) is a psychedelic hallucinogenic drug of the tryptamine family that has a unique effect.

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Dipropyltryptamine

N,N-Dipropyltryptamine (DPT, also known as "The Light") is a psychedelic drug belonging to the tryptamine family, first reported in 1973.

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EDMA

3,4-Ethylenedioxy-N-methylamphetamine (EDMA) is an entactogen drug of the amphetamine class.

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Empathogen–entactogen

Empathogens or entactogens are a class of psychoactive drugs that produce experiences of emotional communion, oneness, relatedness, emotional openness—that is, empathy or sympathy—as particularly observed and reported for experiences with 3,4- Methylenedioxymethamphetamine (MDMA).

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Enantiomer

In chemistry, an enantiomer, also known as an optical isomer (and archaically termed antipode or optical antipode), is one of two stereoisomers that are mirror images of each other that are non-superposable (not identical), much as one's left and right hands are the same except for being reversed along one axis (the hands cannot be made to appear identical simply by reorientation).

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Ethyltrifluoromethylaminoindane

N-Ethyl-5-trifluoromethyl-2-aminoindane (ETAI) is a psychoactive drug and research chemical with putative entactogenic effects.

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Etolorex

Etolorex is an anorectant of the amphetamine class.

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Fenfluramine

Fenfluramine, formerly sold under the brand name Pondimin among others, is an appetite suppressant which was used to treat obesity and is now no longer marketed.

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Flucetorex

Flucetorex (INN) is an amphetamine which was investigated as an anorectic but does not appear to have ever been marketed.

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Indeloxazine

Indeloxazine (INN) (Elen, Noin) is an antidepressant and cerebral activator that was marketed in Japan and South Korea by Yamanouchi Pharmaceutical Co., Ltd for the treatment of psychiatric symptoms associated with cerebrovascular diseases, namely depression resulting from stroke, emotional disturbance, and avolition.

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Levofenfluramine

Levofenfluramine (INN), or (−)-3-trifluoromethyl-N-ethylamphetamine, also known as (−)-fenfluramine or (R)-fenfluramine, is a drug of the amphetamine family that, itself (i.e., in enantiopure form), was never marketed.

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MBDB

1,3-Benzodioxolyl-N-methylbutanamine (N-methyl-1,3-benzodioxolylbutanamine, MBDB, 3,4-methylenedioxy-N-methyl-α-ethylphenylethylamine) is an entactogen of the phenethylamine chemical class.

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MDAI

MDAI (5,6-methylenedioxy-2-aminoindane) is a drug developed in the 1990s by a team led by David E. Nichols at Purdue University.

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MDAT

6,7-Methylenedioxy-2-aminotetralin (MDAT) is a drug developed in the 1990s by a team at Purdue University led by David E. Nichols.

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MDMA

3,4-Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy (E), is a psychoactive drug used primarily as a recreational drug.

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MDMAI

5,6-Methylenedioxy-N-methyl-2-aminoindane (MDMAI), is a drug developed in the 1990s by a team led by David E. Nichols at Purdue University.

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MDMAT

MDMAT (6,7-methylenedioxy-N-methyl-2-aminotetralin) is a putative, non-neurotoxic, selective serotonin releasing agent (SSRA) and entactogen drug.

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Methylenedioxyamphetamine

Methylenedioxyamphetamine may refer to.

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MMAI

5-Methoxy-6-methyl-2-aminoindane (MMAI), is a drug developed in the 1990s by a team led by David E. Nichols at Purdue University.

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Monoamine neurotransmitter

Monoamine neurotransmitters are neurotransmitters and neuromodulators that contain one amino group that is connected to an aromatic ring by a two-carbon chain (such as -CH2-CH2-). All monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, tryptophan, and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes.

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Monoamine oxidase inhibitor

Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B).

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Monoamine releasing agent

A monoamine releasing agent (MRA), or simply monoamine releaser, is a drug that induces the release of a monoamine neurotransmitter from the presynaptic neuron into the synapse, leading to an increase in the extracellular concentrations of the neurotransmitter.

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N,N-Dimethyltryptamine

N,N-Dimethyltryptamine (DMT or N,N-DMT) is a tryptamine molecule which occurs in many plants and animals.

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Neuroprotection

Neuroprotection refers to the relative preservation of neuronal structure and/or function.

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Neurotransmitter

Neurotransmitters are endogenous chemicals that enable neurotransmission.

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Nootropic

Nootropics, also known as smart drugs and cognitive enhancers, are drugs, supplements, and other substances that purport to improve cognitive function, particularly executive functions, memory, creativity, or motivation, in healthy individuals.

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Para-Methoxy-N-ethylamphetamine

para-Methoxyethylamphetamine (PMEA), is a stimulant drug related to PMA.

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Para-Methoxy-N-methylamphetamine

para-Methoxy-N-methylamphetamine (also known as PMMA, Red Mitsubishi), chemically known as methyl-MA, 4-methoxy-N-methylamphetamine, 4-MMA) or (4-PMDA, as listed to its original physical name.) is a stimulant and psychedelic drug closely related to the amphetamine-class serotonergic drug ''para''-methoxyamphetamine (PMA). PMMA is the 4-methoxy analog of methamphetamine. Little is known about the pharmacological properties, metabolism, and toxicity of PMMA; because of its structural similarity to PMA, which has known toxicity in humans, it is thought to have considerable potential to cause harmful side effects or death in overdose. In the early 2010s, a number of deaths in users of the drug MDMA were linked to misrepresented tablets and capsules of PMMA. Its effects in humans are reputedly similar to those of PMA, but slightly more empathogenic in nature. It has a reduced tendency to produce severe hyperthermia at low dosages, but at higher dosages side effects and risk of death becomes similar to those of PMA. The synthesis and effects of PMMA were described by American experimental chemist Alexander Shulgin in his book PiHKAL, where it is referred to by the name "methyl-MA", as the ''N''-methylated form of 4-MA (PMA). Shulgin reported that PMMA produces an increase in blood pressure and in heart rate, at doses above 100 mg, but causes no psychoactive effects at these levels.

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Para-Methoxyamphetamine

para-Methoxyamphetamine (PMA; "Death", "Dr. Death"), also known as 4-methoxyamphetamine (4-MA), is a designer drug of the amphetamine class with serotonergic effects.

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Prodrug

A prodrug is a medication or compound that, after administration, is metabolized (i.e., converted within the body) into a pharmacologically active drug.

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Psilocin

Psilocin (also known as 4-HO-DMT, 4-hydroxy DMT, psilocine, psilocyn, or psilotsin) is a substituted tryptamine alkaloid and a serotonergic psychedelic substance.

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Recreational drug use

Recreational drug use is the use of a psychoactive drug to induce an altered state of consciousness for pleasure, by modifying the perceptions, feelings, and emotions of the user.

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Selective serotonin reuptake inhibitor

Selective serotonin reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder and anxiety disorders.

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Serotonergic psychedelic

Serotonergic psychedelics (also known as serotonergic hallucinogens) are a subclass of psychedelic drugs with a method of action strongly tied to the neurotransmitter serotonin.

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Serotonin

Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.

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Serotonin receptor agonist

A serotonin receptor agonist is an agonist of one or more serotonin receptors.

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Serotonin reuptake inhibitor

A serotonin reuptake inhibitor (SRI) is a type of drug which acts as a reuptake inhibitor of the neurotransmitter serotonin (5-hydroxytryptamine (5-HT)) by blocking the action of the serotonin transporter (SERT).

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Serotonin-norepinephrine-dopamine releasing agent

A serotonin–norepinephrine-dopamine releasing agent (SNDRA), also known as a triple releasing agent (TRA), is a type of drug which induces the release of serotonin, norepinephrine/epinephrine, and dopamine in the brain and body.

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Substituted amphetamine

Substituted amphetamines are a class of compounds based upon the amphetamine structure; it includes all derivative compounds which are formed by replacing, or substituting, one or more hydrogen atoms in the amphetamine core structure with substituents.

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Substituted methylenedioxyphenethylamine

Substituted methylenedioxy- phenethylamines (MDxx) are a large chemical class of derivatives of the phenethylamines, which includes many psychoactive drugs that act as entactogens, psychedelics, and/or stimulants, as well as entheogens.

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Substituted tryptamine

Substituted tryptamines, or serotonin analogues, are organic compounds which may be thought of as being derived from tryptamine itself.

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Trifluoromethylaminoindane

5-Trifluoromethyl-2-aminoindane (TAI) is a psychoactive drug and research chemical with putative entactogenic effects.

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Viqualine

Viqualine (INN) (developmental code name PK-5078) is an antidepressant and anxiolytic drug that was never marketed.

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2-Methyl-MDA

2-Methyl-3,4-methylenedioxyamphetamine (2-methyl-MDA) is an entactogen and psychedelic drug of the amphetamine class.

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3,4-Methylenedioxy-N-ethylamphetamine

3,4-Methylenedioxy-N-ethylamphetamine ("MDEA"; also called "MDE" and colloquially, "Eve") is an empathogenic psychoactive drug.

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3-Methoxy-4-methylamphetamine

3-Methoxy-4-methylamphetamine (MMA) is an entactogen and psychedelic drug of the phenethylamine and amphetamine classes.

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4-Methylaminorex

4-Methylaminorex (4-MAR, 4-MAX) is a stimulant drug of the 2-amino-5-aryloxazoline class that was first synthesized in 1960 by McNeil Laboratories.

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4-Methylthioamphetamine

4-Methylthioamphetamine (4-MTA) is a designer drug developed in the 1990s by a team led by David E. Nichols, an American pharmacologist and medical chemist, at Purdue University.

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5-APDB

5-(2-Aminopropyl)-2,3-dihydrobenzofuran (5-APDB, 3-Desoxy-MDA, EMA-4) is a putative entactogen drug of the phenethylamine and amphetamine classes.

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5-APDI

5-(2-Aminopropyl)-2,3-dihydro-1H-indene (5-APDI), also known as indanylaminopropane (IAP), IAP (psychedelic), 2-API(2-aminopropylindane), indanametamine, and, incorrectly, as indanylamphetamine, is an entactogen and psychedelic drug of the amphetamine family.

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5-HT receptor

5-hydroxytryptamine receptors or 5-HT receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems.

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5-HT2 receptor

The 5-HT2 receptors are a subfamily of 5-HT receptors that bind the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).

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5-HT2B receptor

5-Hydroxytryptamine receptor 2B (5-HT2B) also known as serotonin receptor 2B is a protein that in humans is encoded by the HTR2B gene.

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5-MAPDI

5-(N-Methyl-2-aminopropyl)-2,3-dihydro-1H-indene (5-MAPDI), also known as indanylmethylaminopropane (IMP), is a putative entactogen and selective serotonin releasing agent (SSRA) of the amphetamine family.

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5-Methyl-MDA

5-Methyl-3,4-methylenedioxyamphetamine (5-Methyl-MDA) is an entactogen and psychedelic designer drug of the amphetamine class.

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6-APT

6-(2-Aminopropyl)tetralin (6-APT), also sometimes called tetralinylaminopropane (TAP), is a drug of the amphetamine class which acts as a selective serotonin releasing agent (SSRA).

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6-CAT

6-Chloro-2-aminotetralin (6-CAT) is a drug which acts as a selective serotonin releasing agent (SSRA) and is a putative entactogen in humans.

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5-HT releaser, 5-HT releasing agent, Selective serotonin releaser, Selective serotonin releasing agent, Serotonin releaser, Serotonin releasing agents.

References

[1] https://en.wikipedia.org/wiki/Serotonin_releasing_agent

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