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Sideroblastic anemia

Index Sideroblastic anemia

Sideroblastic anemia or sideroachrestic anemia is a form of anemia in which the bone marrow produces ringed sideroblasts rather than healthy red blood cells (erythrocytes). [1]

59 relations: ABCB7, Acute myeloid leukemia, ALAS2, Anemia, Anisocytosis, Ataxia, Basophilic stippling, Bone marrow, Cell nucleus, Chelation, Chloramphenicol, Codocyte, Copper deficiency, Counterstain, Cycloserine, Deferoxamine, Erythropoietin, Exocrine pancreatic insufficiency, Ferritin, Ferrocyanide, Genetic disorder, GLRX5, Hematocrit, Hematopoietic stem cell transplantation, Heme, Hemoglobin, Hepatomegaly, Isoniazid, Kidney failure, Lead poisoning, Linezolid, List of hematologic conditions, Mean corpuscular volume, Microcytic anemia, Mitochondrion, Myelodysplastic syndrome, Myopathy, Nucleated red blood cell, Online Mendelian Inheritance in Man, Pappenheimer bodies, Platelet, Poikilocytosis, Prussian blue, Pyridoxine, Red blood cell, Red blood cell distribution width, Serum iron, Siderosis, SLC25A38, Spinocerebellar ataxia, ..., Splenomegaly, Thrombocythemia, Total iron-binding capacity, Transferrin saturation, Tumors of the hematopoietic and lymphoid tissues, Vitamin B6, White blood cell, X-inactivation, Zinc toxicity. Expand index (9 more) »


ATP-binding cassette sub-family B member 7, mitochondrial is a protein that in humans is encoded by the ABCB7 gene.

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Acute myeloid leukemia

Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cells.

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Delta-aminolevulinate synthase 2 also known as ALAS2 is a protein that in humans is encoded by the ALAS2 gene.

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Anemia is a decrease in the total amount of red blood cells (RBCs) or hemoglobin in the blood, or a lowered ability of the blood to carry oxygen.

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Anisocytosis is a medical term meaning that a patient's red blood cells are of unequal size.

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Ataxia is a neurological sign consisting of lack of voluntary coordination of muscle movements that includes gait abnormality.

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Basophilic stippling

Basophilic stippling, also known as punctate basophilia, is the presence of numerous basophilic granules that are dispersed through the cytoplasm of erythrocyte in a peripheral blood smear.

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Bone marrow

Bone marrow is a semi-solid tissue which may be found within the spongy or cancellous portions of bones.

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Cell nucleus

In cell biology, the nucleus (pl. nuclei; from Latin nucleus or nuculeus, meaning kernel or seed) is a membrane-enclosed organelle found in eukaryotic cells.

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Chelation is a type of bonding of ions and molecules to metal ions.

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Chloramphenicol is an antibiotic useful for the treatment of a number of bacterial infections.

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Codocytes also known as target cells are red blood cells that have the appearance of a shooting target with a bullseye.

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Copper deficiency

Copper deficiency is a very rare hematological and neurological disorder.

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A counterstain is a stain with colour contrasting to the principal stain, making the stained structure easily visible using a microscope.

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Cycloserine, sold under the brand name Seromycin, is an antibiotic used to treat tuberculosis.

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Deferoxamine (DFOA), sold under the brand name Desferal, is a medication that binds iron and aluminium.

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Erythropoietin (EPO), also known as hematopoietin or hemopoietin, is a glycoprotein cytokine secreted by the kidney in response to cellular hypoxia; it stimulates red blood cell production (erythropoiesis) in the bone marrow.

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Exocrine pancreatic insufficiency

Exocrine pancreatic insufficiency (EPI) is the inability to properly digest food due to a lack of digestive enzymes made by the pancreas.

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Ferritin is a universal intracellular protein that stores iron and releases it in a controlled fashion.

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Ferrocyanide is the name of the anion 4−.

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Genetic disorder

A genetic disorder is a genetic problem caused by one or more abnormalities in the genome.

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Glutaredoxin 5, also known as GLRX5, is a protein which in humans is encoded by the GLRX5 gene located on chromosome 14.

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The hematocrit (Ht or HCT), also known by several other names, is the volume percentage (vol%) of red blood cells in blood.

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Hematopoietic stem cell transplantation

Hematopoietic stem cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood.

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Heme or haem is a coordination complex "consisting of an iron ion coordinated to a porphyrin acting as a tetradentate ligand, and to one or two axial ligands." The definition is loose, and many depictions omit the axial ligands.

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Hemoglobin (American) or haemoglobin (British); abbreviated Hb or Hgb, is the iron-containing oxygen-transport metalloprotein in the red blood cells of all vertebrates (with the exception of the fish family Channichthyidae) as well as the tissues of some invertebrates.

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Hepatomegaly is the condition of having an enlarged liver.

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Isoniazid, also known as isonicotinylhydrazide (INH), is an antibiotic used for the treatment of tuberculosis.

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Kidney failure

Kidney failure, also known as end-stage kidney disease, is a medical condition in which the kidneys no longer work.

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Lead poisoning

Lead poisoning is a type of metal poisoning caused by lead in the body.

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Linezolid is an antibiotic used for the treatment of infections caused by Gram-positive bacteria that are resistant to other antibiotics.

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List of hematologic conditions

There are many conditions of or affecting the human hematologic system — the biological system that includes plasma, platelets, leukocytes, and erythrocytes, the major components of blood and the bone marrow.

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Mean corpuscular volume

The mean corpuscular volume, or mean cell volume (MCV), is a measure of the average volume of a red blood corpuscle (or red blood cell).

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Microcytic anemia

Microcytic anaemia is any of several types of anaemia characterized by small red blood cells (called microcytes).

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The mitochondrion (plural mitochondria) is a double-membrane-bound organelle found in most eukaryotic organisms.

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Myelodysplastic syndrome

Myelodysplastic syndromes (MDS) are a group of cancers in which immature blood cells in the bone marrow do not mature and therefore do not become healthy blood cells.

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Myopathy is a disease of the muscle in which the muscle fibers do not function properly.

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Nucleated red blood cell

With the exception of mammals, all vertebrate organisms have hemoglobin-containing cells in their blood and all of these red blood cells contain a nucleus.

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Online Mendelian Inheritance in Man

Online Mendelian Inheritance in Man (OMIM) is a continuously updated catalog of human genes and genetic disorders and traits, with a particular focus on the gene-phenotype relationship.

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Pappenheimer bodies

Pappenheimer bodies are abnormal basophilic granules of iron found inside red blood cells on routine blood stain.

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Platelets, also called thrombocytes (from Greek θρόμβος, "clot" and κύτος, "cell"), are a component of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot.

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Poikilocytosis refers to the presence of poikilocytes in the blood.

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Prussian blue

Prussian blue is a dark blue pigment produced by oxidation of ferrous ferrocyanide salts.

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Pyridoxine, also known as vitamin B6, is a form of vitamin B6 found commonly in food and used as dietary supplement.

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Red blood cell

Red blood cells-- also known as RBCs, red cells, red blood corpuscles, haematids, erythroid cells or erythrocytes (from Greek erythros for "red" and kytos for "hollow vessel", with -cyte translated as "cell" in modern usage), are the most common type of blood cell and the vertebrate's principal means of delivering oxygen (O2) to the body tissues—via blood flow through the circulatory system.

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Red blood cell distribution width

Red blood cell distribution width (RDW or RDW-CV or RCDW and RDW-SD) is a measure of the range of variation of red blood cell (RBC) volume that is reported as part of a standard complete blood count.

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Serum iron

Serum iron is a medical laboratory test that measures the amount of circulating iron that is bound to transferrin.

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Siderosis is the deposition of excess iron in body tissue.

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SLC25A38 is a human gene.

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Spinocerebellar ataxia

Spinocerebellar ataxia (SCA), also known as spinocerebellar atrophy or spinocerebellar degeneration, is a progressive, degenerative, genetic disease with multiple types, each of which could be considered a disease in its own right.

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Splenomegaly is an enlargement of the spleen.

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Thrombocythemia (also thrombocytosis) is the presence of high platelet (thrombocyte) counts in the blood, and can be either primary (also termed essential thrombocythemia, and caused by a myeloproliferative disease) or secondary (also termed reactive).

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Total iron-binding capacity

Total iron-binding capacity (TIBC) or sometimes transferrin iron-binding capacity is a medical laboratory test that measures the blood's capacity to bind iron with transferrin.

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Transferrin saturation

Transferrin saturation, measured as a percentage, is a medical laboratory value.

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Tumors of the hematopoietic and lymphoid tissues

Tumors of the hematopoietic and lymphoid tissues or haematopoietic and lymphoid malignancies are tumors that affect the blood, bone marrow, lymph, and lymphatic system.

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Vitamin B6

Vitamin B6 refers to a group of chemically similar compounds which can be interconverted in biological systems.

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White blood cell

White blood cells (WBCs), also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.

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X-inactivation (also called lyonization) is a process by which one of the copies of the X chromosome present in female mammals is inactivated.

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Zinc toxicity

Zinc toxicity is a medical condition involving an overdose on, or toxic overexposure to, zinc.

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[1] https://en.wikipedia.org/wiki/Sideroblastic_anemia

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