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Small Cajal body-specific RNA

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Small Cajal body-specific RNAs (scaRNAs) are a class of small nucleolar RNAs (snoRNAs) that specifically localise to the Cajal body, a nuclear organelle (cellular sub-organelle) involved in the biogenesis of small nuclear ribonucleoproteins (snRNPs or snurps). [1]

29 relations: Binding site, Biomolecular structure, Cajal body, Cell nucleus, Drosophila, Gene, Methylation, Molecular and Cellular Biology, Molecular biology, Non-coding RNA, Nucleolar protein, member A1, Nucleolus, Organelle, Protein, Pseudouridine, Ribosomal RNA, RNA polymerase II, Small nuclear RNA, Small nucleolar RNA, SnRNP, Spliceosome, Transcription (biology), Translation (biology), U1 spliceosomal RNA, U12 minor spliceosomal RNA, U2 spliceosomal RNA, U4 spliceosomal RNA, U5 spliceosomal RNA, Vertebrate.

Binding site

In biochemistry, a binding site is a region on a protein or piece of DNA or RNA to which ligands (specific molecules and/or ions) may form a chemical bond.

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Biomolecular structure

Biomolecular structure is the intricate folded, three-dimensional shape that is formed by a molecule of protein, DNA, or RNA, and that is important to its function.

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Cajal body

Cajal bodies (CBs) also coiled bodies, are spherical sub-organelles of 0.3–1.0 µm in diameter found in the nucleus of proliferative cells like embryonic cells and tumor cells, or metabolically active cells like neurons.

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Cell nucleus

In cell biology, the nucleus (pl. nuclei; from Latin nucleus or nuculeus, meaning kernel or seed) is a membrane-enclosed organelle found in eukaryotic cells.

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Drosophila

Drosophila is a genus of flies, belonging to the family Drosophilidae, whose members are often called "small fruit flies" or (less frequently) pomace flies, vinegar flies, or wine flies, a reference to the characteristic of many species to linger around overripe or rotting fruit.

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Gene

In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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Methylation

In the chemical sciences, methylation denotes the addition of a methyl group on a substrate, or the substitution of an atom (or group) by a methyl group.

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Molecular and Cellular Biology

Molecular and Cellular Biology is a bimonthly peer-reviewed scientific journal published by the American Society for Microbiology.

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Molecular biology

Molecular biology is a branch of biology which concerns the molecular basis of biological activity between biomolecules in the various systems of a cell, including the interactions between DNA, RNA, proteins and their biosynthesis, as well as the regulation of these interactions.

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Non-coding RNA

A non-coding RNA (ncRNA) is an RNA molecule that is not translated into a protein.

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Nucleolar protein, member A1

H/ACA ribonucleoprotein complex subunit 1 is a protein that in humans is encoded by the GAR1 gene.

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Nucleolus

The nucleolus (plural nucleoli) is the largest structure in the nucleus of eukaryotic cells.

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Organelle

In cell biology, an organelle is a specialized subunit within a cell that has a specific function, in which their function is vital for the cell to live.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Pseudouridine

Pseudouridine (abbreviated by the Greek letter psi- Ψ or the letter Q) is an isomer of the nucleoside uridine in which the uracil is attached via a carbon-carbon instead of a nitrogen-carbon glycosidic bond.

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Ribosomal RNA

Ribosomal ribonucleic acid (rRNA) is the RNA component of the ribosome, and is essential for protein synthesis in all living organisms.

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RNA polymerase II

RNA polymerase II (RNAP II and Pol II) is a multiprotein complex.

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Small nuclear RNA

Small nuclear ribonucleic acid (snRNA), also commonly referred to as U-RNA, is a class of small RNA molecules that are found within the splicing speckles and Cajal bodies of the cell nucleus in eukaryotic cells.

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Small nucleolar RNA

Small nucleolar RNAs (snoRNAs) are a class of small RNA molecules that primarily guide chemical modifications of other RNAs, mainly ribosomal RNAs, transfer RNAs and small nuclear RNAs.

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SnRNP

snRNPs (pronounced "snurps"), or small nuclear ribonucleoproteins, are RNA-protein complexes that combine with unmodified pre-mRNA and various other proteins to form a spliceosome, a large RNA-protein molecular complex upon which splicing of pre-mRNA occurs.

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Spliceosome

A spliceosome is a large and complex molecular machine found primarily within the splicing speckles of the cell nucleus of eukaryotic cells.

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Transcription (biology)

Transcription is the first step of gene expression, in which a particular segment of DNA is copied into RNA (especially mRNA) by the enzyme RNA polymerase.

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Translation (biology)

In molecular biology and genetics, translation is the process in which ribosomes in the cytoplasm or ER synthesize proteins after the process of transcription of DNA to RNA in the cell's nucleus.

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U1 spliceosomal RNA

U1 spliceosomal RNA is the small nuclear RNA (snRNA) component of U1 snRNP (small nuclear ribonucleoprotein), an RNA-protein complex that combines with other snRNPs, unmodified pre-mRNA, and various other proteins to assemble a spliceosome, a large RNA-protein molecular complex upon which splicing of pre-mRNA occurs.

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U12 minor spliceosomal RNA

U12 minor spliceosomal RNA is formed from U12 small nuclear (snRNA), together with U4atac/U6atac, U5, and U11 snRNAs and associated proteins, forms a spliceosome that cleaves a divergent class of low-abundance pre-mRNA introns.

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U2 spliceosomal RNA

U2 spliceosomal snRNAs are a species of small nuclear RNA (snRNA) molecules found in the major spliceosomal (Sm) machinery of virtually all-eukaryotic organisms.

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U4 spliceosomal RNA

The U4 small nuclear Ribo-Nucleic Acid (U4 snRNA) is a non-coding RNA component of the major or U2-dependent spliceosome – a eukaryotic molecular machine involved in the splicing of pre-messenger RNA (pre-mRNA).

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U5 spliceosomal RNA

U5 RNA is a non-coding RNA that is a component of both types of known spliceosome.

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Vertebrate

Vertebrates comprise all species of animals within the subphylum Vertebrata (chordates with backbones).

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Cajal Body specific RNA, ScaRNA, ScaRNA 1, ScaRNAs, Small Cajal body RNA, Small Cajal body RNAs, Small Cajal body specific RNA, Small Cajal body specific RNA 1, Small Cajal body specific RNAs, Small Cajal body-specific RNAs, Small cajal body specific RNA.

References

[1] https://en.wikipedia.org/wiki/Small_Cajal_body-specific_RNA

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