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62 relations: Adenosine, Animal, Arginine, Autoantibody, C-terminus, Cajal body, Cell nucleus, Chaperone (protein), Complementarity (molecular biology), Cryogenic electron microscopy, Cytoplasm, DDX20, Eukaryote, Gel electrophoresis, Gem-associated protein 2, Gem-associated protein 4, Gem-associated protein 5, Gem-associated protein 6, Gem-associated protein 7, GEMIN8, Gideon Dreyfuss, Glycine, Guanosine, Intron, Joan A. Steitz, LSm, Messenger RNA, Michael R. Lerner, Non-coding RNA, Nucleoside, Nucleotide, Post-transcriptional modification, Post-translational modification, Precursor mRNA, Protein, Protein complex, Protein Data Bank, Ribosomal RNA, Ribosome, RNA, RNA polymerase II, RNA splicing, Single particle analysis, Small nuclear RNA, SMN1, Spinal muscular atrophy, Spliceosome, Survival of motor neuron, Systemic lupus erythematosus, U1 spliceosomal RNA, ..., U11 spliceosomal RNA, U12 minor spliceosomal RNA, U2 spliceosomal RNA, U4 spliceosomal RNA, U4atac minor spliceosomal RNA, U5 spliceosomal RNA, U6 spliceosomal RNA, U6atac minor spliceosomal RNA, U7 small nuclear RNA, Uridine, X-ray crystallography, 7-Methylguanosine. Expand index (12 more) »
Adenosine
Adenosine is both a chemical found in many living systems and a medication.
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Animal
Animals are multicellular eukaryotic organisms that form the biological kingdom Animalia.
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Arginine
Arginine (symbol Arg or R) is an α-amino acid that is used in the biosynthesis of proteins.
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Autoantibody
An autoantibody is an antibody (a type of protein) produced by the immune system that is directed against one or more of the individual's own proteins.
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C-terminus
The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH).
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Cajal body
Cajal bodies (CBs) also coiled bodies, are spherical sub-organelles of 0.3–1.0 µm in diameter found in the nucleus of proliferative cells like embryonic cells and tumor cells, or metabolically active cells like neurons.
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Cell nucleus
In cell biology, the nucleus (pl. nuclei; from Latin nucleus or nuculeus, meaning kernel or seed) is a membrane-enclosed organelle found in eukaryotic cells.
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Chaperone (protein)
In molecular biology, molecular chaperones are proteins that assist the covalent folding or unfolding and the assembly or disassembly of other macromolecular structures.
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Complementarity (molecular biology)
In molecular biology, complementarity describes a relationship between two structures each following the lock-and-key principle.
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Cryogenic electron microscopy
Electron cryomicroscopy (CryoEM) is an electron microscopy (EM) technique where the sample is cooled to cryogenic temperatures.
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Cytoplasm
In cell biology, the cytoplasm is the material within a living cell, excluding the cell nucleus.
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DDX20
Probable ATP-dependent RNA helicase DDX20, also known as DEAD-box helicase 20 and gem-associated protein 3 (GEMIN3), is an enzyme that in humans is encoded by the DDX20 gene.
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Eukaryote
Eukaryotes are organisms whose cells have a nucleus enclosed within membranes, unlike Prokaryotes (Bacteria and other Archaea).
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Gel electrophoresis
Gel electrophoresis is a method for separation and analysis of macromolecules (DNA, RNA and proteins) and their fragments, based on their size and charge.
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Gem-associated protein 2
Gem-associated protein 2 (GEMIN2), also called survival of motor neuron protein-interacting protein 1 (SIP1), is a protein that in humans is encoded by the GEMIN2 gene.
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Gem-associated protein 4
Gem-associated protein 4 is a protein that in humans is encoded by the GEMIN4 gene.
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Gem-associated protein 5
Gem-associated protein 5 is a protein that in humans is encoded by the GEMIN5 gene.
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Gem-associated protein 6
Gem-associated protein 6 is a protein that in humans is encoded by the GEMIN6 gene.
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Gem-associated protein 7
Gem-associated protein 7 is a protein that in humans is encoded by the GEMIN7 gene.
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GEMIN8
Gem-associated protein 8 (Gemin-8) is a protein that in humans is encoded by the GEMIN8 gene.
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Gideon Dreyfuss
Dr.
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Glycine
Glycine (symbol Gly or G) is the amino acid that has a single hydrogen atom as its side chain.
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Guanosine
Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond.
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Intron
An intron is any nucleotide sequence within a gene that is removed by RNA splicing during maturation of the final RNA product.
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Joan A. Steitz
Joan Elaine Argetsinger Steitz (born January 26, 1941) is Sterling Professor of Molecular Biophysics and Biochemistry at Yale University and Investigator at the Howard Hughes Medical Institute.
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LSm
In molecular biology, LSm proteins are a family of RNA-binding proteins found in virtually every cellular organism.
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Messenger RNA
Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression.
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Michael R. Lerner
Michael Rush Lerner is a dermatologist in San Diego, California.
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Non-coding RNA
A non-coding RNA (ncRNA) is an RNA molecule that is not translated into a protein.
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Nucleoside
Nucleosides are glycosylamines that can be thought of as nucleotides without a phosphate group.
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Nucleotide
Nucleotides are organic molecules that serve as the monomer units for forming the nucleic acid polymers deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essential biomolecules within all life-forms on Earth.
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Post-transcriptional modification
Post-transcriptional modification or Co-transcriptional modification is the process in eukaryotic cells where primary transcript RNA is converted into mature RNA.
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Post-translational modification
Post-translational modification (PTM) refers to the covalent and generally enzymatic modification of proteins following protein biosynthesis.
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Precursor mRNA
Precursor mRNA (pre-mRNA) is an immature single strand of messenger ribonucleic acid (mRNA).
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Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
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Protein complex
A protein complex or multiprotein complex is a group of two or more associated polypeptide chains.
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Protein Data Bank
The Protein Data Bank (PDB) is a crystallographic database for the three-dimensional structural data of large biological molecules, such as proteins and nucleic acids.
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Ribosomal RNA
Ribosomal ribonucleic acid (rRNA) is the RNA component of the ribosome, and is essential for protein synthesis in all living organisms.
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Ribosome
The ribosome is a complex molecular machine, found within all living cells, that serves as the site of biological protein synthesis (translation).
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RNA
Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation, and expression of genes.
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RNA polymerase II
RNA polymerase II (RNAP II and Pol II) is a multiprotein complex.
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RNA splicing
In molecular biology, splicing is the editing of the nascent precursor messenger RNA (pre-mRNA) transcript into a mature messenger RNA (mRNA).
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Single particle analysis
Single particle analysis is a group of related computerized image processing techniques used to analyze images from transmission electron microscopy (TEM).
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Small nuclear RNA
Small nuclear ribonucleic acid (snRNA), also commonly referred to as U-RNA, is a class of small RNA molecules that are found within the splicing speckles and Cajal bodies of the cell nucleus in eukaryotic cells.
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SMN1
Survival of motor neuron 1 (SMN1), also known as component of gems 1 or GEMIN1, is a gene that encodes the SMN protein in humans.
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Spinal muscular atrophy
Spinal muscular atrophy (SMA) is a rare neuromuscular disorder characterised by loss of motor neurons and progressive muscle wasting, often leading to early death.
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Spliceosome
A spliceosome is a large and complex molecular machine found primarily within the splicing speckles of the cell nucleus of eukaryotic cells.
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Survival of motor neuron
Survival of motor neuron or survival motor neuron (SMN) is a protein that in humans is encoded by the SMN1 and SMN2 genes.
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Systemic lupus erythematosus
Systemic lupus erythematosus (SLE), also known simply as lupus, is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body.
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U1 spliceosomal RNA
U1 spliceosomal RNA is the small nuclear RNA (snRNA) component of U1 snRNP (small nuclear ribonucleoprotein), an RNA-protein complex that combines with other snRNPs, unmodified pre-mRNA, and various other proteins to assemble a spliceosome, a large RNA-protein molecular complex upon which splicing of pre-mRNA occurs.
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U11 spliceosomal RNA
The U11 snRNA (small nuclear ribonucleic acid) is an important non-coding RNA in the minor spliceosome protein complex, which activates the alternative splicing mechanism.
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U12 minor spliceosomal RNA
U12 minor spliceosomal RNA is formed from U12 small nuclear (snRNA), together with U4atac/U6atac, U5, and U11 snRNAs and associated proteins, forms a spliceosome that cleaves a divergent class of low-abundance pre-mRNA introns.
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U2 spliceosomal RNA
U2 spliceosomal snRNAs are a species of small nuclear RNA (snRNA) molecules found in the major spliceosomal (Sm) machinery of virtually all-eukaryotic organisms.
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U4 spliceosomal RNA
The U4 small nuclear Ribo-Nucleic Acid (U4 snRNA) is a non-coding RNA component of the major or U2-dependent spliceosome – a eukaryotic molecular machine involved in the splicing of pre-messenger RNA (pre-mRNA).
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U4atac minor spliceosomal RNA
U4atac minor spliceosomal RNA is a ncRNA which is an essential component of the minor U12-type spliceosome complex.
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U5 spliceosomal RNA
U5 RNA is a non-coding RNA that is a component of both types of known spliceosome.
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U6 spliceosomal RNA
U6 snRNA is the non-coding small nuclear RNA (snRNA) component of U6 snRNP (small nuclear ribonucleoprotein), an RNA-protein complex that combines with other snRNPs, unmodified pre-mRNA, and various other proteins to assemble a spliceosome, a large RNA-protein molecular complex that catalyzes the excision of introns from pre-mRNA.
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U6atac minor spliceosomal RNA
U6atac minor spliceosomal RNA is a non-coding RNA which is an essential component of the minor U12-type spliceosome complex.
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U7 small nuclear RNA
The U7 small nuclear RNA (U7 snRNA) is an RNA molecule and a component of the small nuclear ribonucleoprotein complex (U7 snRNP).
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Uridine
Uridine is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, a ribofuranose) via a β-N1-glycosidic bond.
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X-ray crystallography
X-ray crystallography is a technique used for determining the atomic and molecular structure of a crystal, in which the crystalline atoms cause a beam of incident X-rays to diffract into many specific directions.
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7-Methylguanosine
7-Methylguanosine (m7G) is a modified purine nucleoside.
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Di-snRNP, Ribonucleoproteins, small nuclear, Ribonucleoproteins, small nucleolar, Small Nuclear Ribonucleoprotein Particles, Small nuclear RNP, Small nuclear ribonucleic particle, Small nuclear ribonucleoprotein, Snerp, Snrp, Snurp, Snurps, Tri-snRNP.
References
[1] https://en.wikipedia.org/wiki/SnRNP
