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Stop codon

Index Stop codon

In molecular biology, a stop codon (or termination codon) is a codon (nucleotide triplet within messenger RNA) that signals the termination of the translation process of the current protein. [1]

Table of Contents

  1. 54 relations: Amber, Ambush hypothesis, Amino acid, Bacteriophage, Blastocrithidia nuclear code, Charles M. Steinberg, Condylostoma nuclear code, Craig Venter, Cytotoxicity, DNA and RNA codon tables, Endocrine system, Escherichia coli, Escherichia virus T4, GC-content, Genetic code, Initiation factor, Karyorelict nuclear code, Lambda phage, Louisiana State University, Malate dehydrogenase, Messenger RNA, Missense mutation, Mitochondrial DNA, Molecular biology, Neurodevelopmental disorder, Nonsense mutation, Nucleotide, Null-terminated string, Ochre, Opal, Peptide, Point mutation, Protein, Pyrrolysine, Release factor, Ribosomal frameshift, Ribosomal RNA, Ribosome, Scenedesmus obliquus mitochondrial code, Selenocysteine, Start codon, Sydney Brenner, Synthetic biology, Terminator (genetics), Tetradesmus obliquus, Thraustochytrids, Thraustochytrium mitochondrial code, Transfer RNA, Translation (biology), Umber, ... Expand index (4 more) »

Amber

Amber is fossilized tree resin.

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Ambush hypothesis

The ambush hypothesis is a hypothesis in the field of molecular genetics that suggests that the prevalence of “hidden” or off-frame stop codons in DNA selectively deters off-frame translation of mRNA to save energy, molecular resources, and to reduce strain on biosynthetic machinery by truncating the production of non-functional, potentially cytotoxic protein products. Stop codon and ambush hypothesis are gene expression and molecular genetics.

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Amino acid

Amino acids are organic compounds that contain both amino and carboxylic acid functional groups.

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Bacteriophage

A bacteriophage, also known informally as a phage, is a virus that infects and replicates within bacteria and archaea.

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Blastocrithidia nuclear code

The Blastocrithidia nuclear code (translation table 31) is a genetic code used by the nuclear genome of the trypanosomatid genus Blastocrithidia. Stop codon and Blastocrithidia nuclear code are gene expression and molecular genetics.

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Charles M. Steinberg

Charles 'Charley' M. Steinberg (1932 September 17, 1999) was an immunobiologist and permanent member of the Basel Institute for Immunology.

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Condylostoma nuclear code

The Condylostoma nuclear code (translation table 28) is a genetic code used by the nuclear genome of the heterotrich ciliate Condylostoma magnum. Stop codon and Condylostoma nuclear code are gene expression and molecular genetics.

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Craig Venter

John Craig Venter (born October 14, 1946) is an American biotechnologist and businessman.

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Cytotoxicity

Cytotoxicity is the quality of being toxic to cells.

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DNA and RNA codon tables

A codon table can be used to translate a genetic code into a sequence of amino acids. Stop codon and DNA and RNA codon tables are gene expression and molecular genetics.

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Endocrine system

The endocrine system is a messenger system in an organism comprising feedback loops of hormones that are released by internal glands directly into the circulatory system and that target and regulate distant organs.

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Escherichia coli

Escherichia coliWells, J. C. (2000) Longman Pronunciation Dictionary.

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Escherichia virus T4

Escherichia virus T4 is a species of bacteriophages that infect Escherichia coli bacteria.

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GC-content

In molecular biology and genetics, GC-content (or guanine-cytosine content) is the percentage of nitrogenous bases in a DNA or RNA molecule that are either guanine (G) or cytosine (C).

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Genetic code

The genetic code is the set of rules used by living cells to translate information encoded within genetic material (DNA or RNA sequences of nucleotide triplets, or codons) into proteins. Stop codon and genetic code are gene expression and molecular genetics.

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Initiation factor

In molecular biology, initiation factors are proteins that bind to the small subunit of the ribosome during the initiation of translation, a part of protein biosynthesis. Stop codon and initiation factor are gene expression.

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Karyorelict nuclear code

The karyorelictid nuclear code (translation table 27) is a genetic code used by the nuclear genome of the Karyorelictea ciliate Parduczia sp. Stop codon and karyorelict nuclear code are gene expression and molecular genetics.

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Lambda phage

Enterobacteria phage λ (lambda phage, coliphage λ, officially Escherichia virus Lambda) is a bacterial virus, or bacteriophage, that infects the bacterial species Escherichia coli (E. coli).

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Louisiana State University

Louisiana State University (officially Louisiana State University and Agricultural and Mechanical College, commonly referred to as LSU) is an American public land-grant research university in Baton Rouge, Louisiana.

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Malate dehydrogenase

Malate dehydrogenase (MDH) is an enzyme that reversibly catalyzes the oxidation of malate to oxaloacetate using the reduction of NAD+ to NADH.

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Messenger RNA

In molecular biology, messenger ribonucleic acid (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is read by a ribosome in the process of synthesizing a protein. Stop codon and messenger RNA are gene expression and molecular genetics.

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Missense mutation

In genetics, a missense mutation is a point mutation in which a single nucleotide change results in a codon that codes for a different amino acid.

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Mitochondrial DNA

Mitochondrial DNA (mtDNA and mDNA) is the DNA located in the mitochondria organelles in a eukaryotic cell that converts chemical energy from food into adenosine triphosphate (ATP).

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Molecular biology

Molecular biology is a branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions.

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Neurodevelopmental disorder

Neurodevelopmental disorders are a group of conditions that begin to emerge during childhood (or the development of the nervous system).

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Nonsense mutation

In genetics, a nonsense mutation is a point mutation in a sequence of DNA that results in a nonsense codon, or a premature stop codon in the transcribed mRNA, and leads to a truncated, incomplete, and possibly nonfunctional protein product.

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Nucleotide

Nucleotides are organic molecules composed of a nitrogenous base, a pentose sugar and a phosphate.

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Null-terminated string

In computer programming, a null-terminated string is a character string stored as an array containing the characters and terminated with a null character (a character with an internal value of zero, called "NUL" in this article, not same as the glyph zero).

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Ochre

Ochre, iron ochre, or ocher in American English, is a natural clay earth pigment, a mixture of ferric oxide and varying amounts of clay and sand.

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Opal

Opal is a hydrated amorphous form of silica (SiO2·nH2O); its water content may range from 3% to 21% by weight, but is usually between 6% and 10%.

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Peptide

Peptides are short chains of amino acids linked by peptide bonds.

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Point mutation

A point mutation is a genetic mutation where a single nucleotide base is changed, inserted or deleted from a DNA or RNA sequence of an organism's genome.

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Protein

Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues.

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Pyrrolysine

Pyrrolysine (symbol Pyl or O; encoded by the 'amber' stop codon UAG) is an α-amino acid that is used in the biosynthesis of proteins in some methanogenic archaea and bacteria; it is not present in humans.

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Release factor

A release factor is a protein that allows for the termination of translation by recognizing the termination codon or stop codon in an mRNA sequence.

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Ribosomal frameshift

Ribosomal frameshifting, also known as translational frameshifting or translational recoding, is a biological phenomenon that occurs during translation that results in the production of multiple, unique proteins from a single mRNA. Stop codon and Ribosomal frameshift are gene expression.

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Ribosomal RNA

Ribosomal ribonucleic acid (rRNA) is a type of non-coding RNA which is the primary component of ribosomes, essential to all cells.

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Ribosome

Ribosomes are macromolecular machines, found within all cells, that perform biological protein synthesis (messenger RNA translation).

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Scenedesmus obliquus mitochondrial code

The Scenedesmus obliquus mitochondrial code (translation table 22) is a genetic code found in the mitochondria of Scenedesmus obliquus, a species of green algae. Stop codon and Scenedesmus obliquus mitochondrial code are gene expression and molecular genetics.

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Selenocysteine

Selenocysteine (symbol Sec or U, in older publications also as Se-Cys) is the 21st proteinogenic amino acid.

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Start codon

The start codon is the first codon of a messenger RNA (mRNA) transcript translated by a ribosome. Stop codon and start codon are molecular genetics.

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Sydney Brenner

Sydney Brenner (13 January 1927 – 5 April 2019) was a South African biologist.

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Synthetic biology

Synthetic biology (SynBio) is a multidisciplinary field of science that focuses on living systems and organisms, and it applies engineering principles to develop new biological parts, devices, and systems or to redesign existing systems found in nature. Stop codon and Synthetic biology are molecular genetics.

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Terminator (genetics)

In genetics, a transcription terminator is a section of nucleic acid sequence that marks the end of a gene or operon in genomic DNA during transcription. Stop codon and terminator (genetics) are gene expression.

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Tetradesmus obliquus

Tetradesmus obliquus is a green algae species of the family Scenedesmaceae. It is commonly known by its synonym, Scenedesmus obliquus. It is a common species found in a variety of freshwater habitats. Tetradesmus obliquus forms colonies of two or four (occasionally eight) cells in a single row; in culture, solitary cells are often present.

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Thraustochytrids

Thraustochytrids are single-celled saprotrophic eukaryotes (decomposers) that are widely distributed in marine ecosystems, and which secrete enzymes including, but not limited to amylases, proteases, phosphatases.

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Thraustochytrium mitochondrial code

The Thraustochytrium mitochondrial code (translation table 23) is a genetic code found in the mitochondria of the labyrinthulid protist Thraustochytrium aureum. Stop codon and Thraustochytrium mitochondrial code are gene expression and molecular genetics.

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Transfer RNA

Transfer RNA (abbreviated tRNA and formerly referred to as sRNA, for soluble RNA) is an adaptor molecule composed of RNA, typically 76 to 90 nucleotides in length (in eukaryotes), that serves as the physical link between the mRNA and the amino acid sequence of proteins.

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Translation (biology)

In biology, translation is the process in living cells in which proteins are produced using RNA molecules as templates. Stop codon and translation (biology) are gene expression.

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Umber

Umber is a natural earth pigment consisting of iron oxide and manganese oxide; it has a brownish color that can vary among shades of yellow, red, and green.

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University of Memphis

The University of Memphis (Memphis) is a public research university in Memphis, Tennessee.

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Vertebrate

Vertebrates are deuterostomal animals with bony or cartilaginous axial endoskeleton — known as the vertebral column, spine or backbone — around and along the spinal cord, including all fish, amphibians, reptiles, birds and mammals.

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Vertebrate mitochondrial code

The vertebrate mitochondrial code (translation table 2) is the genetic code found in the mitochondria of all vertebrata. Stop codon and vertebrate mitochondrial code are gene expression and molecular genetics.

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Virus

A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism.

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References

[1] https://en.wikipedia.org/wiki/Stop_codon

Also known as Amber codon, Amber mutation, Amber suppressor, Hidden stop, Nonstop mutation, Ochre codon, Ochre mutation, Opal codon, Premature termination codon, Stop codons, Stop-codon, Termination Codon.

, University of Memphis, Vertebrate, Vertebrate mitochondrial code, Virus.