136 relations: Adrenaline, Allylescaline, Amfepramone, Amine, Amphetamine, Anorectic, Antidepressant, Antihypotensive agent, Antiparkinson medication, Asymbescaline, Beta2-adrenergic agonist, Biological target, Bromine, Bronchodilator, Bupropion, Cathine, Cathinone, Central nervous system, Chemical classification, Chlorine, Cyclopropanation, Decongestant, Derivative (chemistry), Dopamine, DOx, Drug class, Empathogen–entactogen, Endogeny (biology), Ephedrine, Ethcathinone, Euphoria, Fenfluramine, Fluorine, Food additive, Hallucinogen, Hormone, Hydrogen atom, Hydroxy group, Iodine, Levomethamphetamine, MDMA, Mechanism of action, Mephedrone, Mescaline, Meta-Tyramine, Metaescaline, Methallylescaline, Methamphetamine, Methcathinone, Methoxy group, ..., Methyl group, Methylenedioxy, Methylone, Methylphenidate, Moiety (chemistry), Monoamine neurotransmitter, Monoamine releasing agent, N,N-Dimethylphenethylamine, N-Methylphenethylamine, NBOMe-mescaline, Neurotoxin, Neurotransmitter, Nitro compound, Norepinephrine, Norepinephrine releasing agent, Norepinephrine–dopamine reuptake inhibitor, Norfenefrine, Norfenfluramine, Octopamine (neurotransmitter), Organic compound, Ortetamine, Oxidopamine, Phenelzine, Phenethylamine, Phentermine, Phenyl group, Phenylephrine, Propyl group, Proscaline, Pseudoephedrine, Psychedelic drug, Psychoactive drug, Recreational drug use, Salbutamol, Selegiline, Serotonin releasing agent, Stimulant, Structural formula, Substituent, Substituted amphetamine, Substituted cathinone, Substituted methylenedioxyphenethylamine, Substituted phenylmorpholine, Substituted tryptamine, Substitution reaction, Thio-, Thyronamine, Trace amine, Trifluoromethyl, Tyramine, 2,5-Dimethoxy-4-bromoamphetamine, 2,5-Dimethoxy-4-chloroamphetamine, 2,5-Dimethoxy-4-iodoamphetamine, 2,5-Dimethoxy-4-methylamphetamine, 2,5-Dimethoxy-4-nitroamphetamine, 25-NB, 25B-NBOH, 25B-NBOMe, 25C-NBOH, 25C-NBOMe, 25D-NBOMe, 25E-NBOMe, 25I-NBF, 25I-NBOH, 25I-NBOMe, 25P-NBOMe, 2C (psychedelics), 2C-B, 2C-C, 2C-D, 2C-E, 2C-F, 2C-I, 2C-N, 2C-P, 2C-T-19, 2C-T-2, 2C-T-21, 2C-T-4, 2C-T-7, 2C-T-8, 3,4-Methylenedioxy-N-ethylamphetamine, 3,4-Methylenedioxyamphetamine, 3-Iodothyronamine, 5-APB, 6-APB. Expand index (86 more) » « Shrink index
Adrenaline, also known as adrenalin or epinephrine, is a hormone, neurotransmitter, and medication.
Allylescaline, or 4-allyloxy-3,5-dimethoxyphenethylamine, is a lesser-known psychedelic drug.
Amfepramone is a stimulant drug of the phenethylamine, amphetamine, and cathinone classes that is used as an appetite suppressant.
In organic chemistry, amines are compounds and functional groups that contain a basic nitrogen atom with a lone pair.
Amphetamine (contracted from) is a potent central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity.
An anorectic or anorexic is a drug which reduces appetite, resulting in lower food consumption, leading to weight loss.
Antidepressants are drugs used for the treatment of major depressive disorder and other conditions, including dysthymia, anxiety disorders, obsessive–compulsive disorder, eating disorders, chronic pain, neuropathic pain and, in some cases, dysmenorrhoea, snoring, migraine, attention-deficit hyperactivity disorder (ADHD), addiction, dependence, and sleep disorders.
An antihypotensive agent, also known as a vasopressor agent or pressor, is any medication that tends to raise reduced blood pressure.
An antiparkinson medication is a type of drug which is intended to treat and relieve the symptoms of Parkinson's disease.
Asymbescaline, or 3,4-diethoxy-5-methoxyphenethylamine, is a lesser-known psychedelic drug.
β2 (beta2) adrenergic receptor agonists, also known as adrenergic β2 receptor agonists, are a class of drugs that act on the β2 adrenergic receptor.
A biological target is anything within a living organism to which some other entity (like an endogenous ligand or a drug) is directed and/or binds, resulting in a change in its behavior or function.
Bromine is a chemical element with symbol Br and atomic number 35.
A bronchodilator is a substance that dilates the bronchi and bronchioles, decreasing resistance in the respiratory airway and increasing airflow to the lungs.
Bupropion, sold under the brand names Wellbutrin and Zyban among others, is a medication primarily used as an antidepressant and smoking cessation aid.
Cathine, also known as -norpseudoephedrine and (+)-norpseudoephedrine, is a psychoactive drug of the phenethylamine and amphetamine chemical classes which acts as a stimulant.
Cathinone (also known as benzoylethanamine, or β-keto-amphetamine) is a monoamine alkaloid found in the shrub Catha edulis (khat) and is chemically similar to ephedrine, cathine, methcathinone and other amphetamines.
The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.
Chemical classification systems attempt to classify elements or compounds according to certain chemical functional or structural properties.
Chlorine is a chemical element with symbol Cl and atomic number 17.
Cyclopropanation refers to any chemical process which generates cyclopropane rings.
A decongestant, or nasal decongestant, is a type of pharmaceutical drug that is used to relieve nasal congestion in the upper respiratory tract.
In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.
Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is an organic chemical of the catecholamine and phenethylamine families that plays several important roles in the brain and body.
4-substituted-2,5-Dimethoxyamphetamines (DOx) is a chemical class of substituted amphetamine derivatives featuring methoxy groups at the 2- and 5- positions of the phenyl ring, and a substituent such as alkyl or halogen at the 4- position of the phenyl ring.
A drug class is a set of medications that have similar chemical structures, the same mechanism of action (i.e., bind to the same biological target), a related mode of action, and/or are used to treat the same disease.
Empathogens or entactogens are a class of psychoactive drugs that produce experiences of emotional communion, oneness, relatedness, emotional openness—that is, empathy or sympathy—as particularly observed and reported for experiences with 3,4- Methylenedioxymethamphetamine (MDMA).
Endogenous substances and processes are those that originate from within an organism, tissue, or cell.
Ephedrine is a medication and stimulant.
Ethcathinone, also known as ethylpropion or ETH-CAT, is a stimulant drug of the phenethylamine, amphetamine, and cathinone chemical classes.
Euphoria is an affective state in which a person experiences pleasure or excitement and intense feelings of well-being and happiness.
Fenfluramine, formerly sold under the brand name Pondimin among others, is an appetite suppressant which was used to treat obesity and is now no longer marketed.
Fluorine is a chemical element with symbol F and atomic number 9.
Food additives are substances added to food to preserve flavor or enhance its taste, appearance, or other qualities.
A hallucinogen is a psychoactive agent which can cause hallucinations, perceptual anomalies, and other substantial subjective changes in thoughts, emotion, and consciousness.
A hormone (from the Greek participle “ὁρμῶ”, "to set in motion, urge on") is any member of a class of signaling molecules produced by glands in multicellular organisms that are transported by the circulatory system to target distant organs to regulate physiology and behaviour.
A hydrogen atom is an atom of the chemical element hydrogen.
A hydroxy or hydroxyl group is the entity with the formula OH.
Iodine is a chemical element with symbol I and atomic number 53.
LevomethamphetamineOther names include l-methamphetamine, levodesoxyephedrine, l-desoxyephedrine, levmetamfetamine (INN and USAN).
3,4-Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy (E), is a psychoactive drug used primarily as a recreational drug.
In pharmacology, the term mechanism of action (MOA) refers to the specific biochemical interaction through which a drug substance produces its pharmacological effect.
Mephedrone, also known as 4-methyl methcathinone (4-MMC) or 4-methyl ephedrone, is a synthetic stimulant drug of the amphetamine and cathinone classes.
Mescaline (3,4,5-trimethoxyphenethylamine) is a naturally occurring psychedelic alkaloid of the phenethylamine class, known for its hallucinogenic effects comparable to those of LSD and psilocybin.
meta-Tyramine, also known as m-tyramine and 3-tyramine, is an endogenous trace amine neuromodulator and a structural analog of phenethylamine.
Metaescaline, or 3,4-dimethoxy-5-ethoxyphenethylamine, is a lesser-known psychedelic drug.
Methallylescaline (4-methylallyloxy-3,5-dimethoxyphenethylamine) is a lesser-known psychedelic drug.
Methamphetamine (contracted from) is a potent central nervous system (CNS) stimulant that is mainly used as a recreational drug and less commonly as a second-line treatment for attention deficit hyperactivity disorder and obesity.
Methcathinone (α-methylamino-propiophenone or ephedrone) (sometimes called "cat" or "jeff" or "catnip" or "intash") is a monoamine alkaloid and psychoactive stimulant, a substituted cathinone.
A methoxy group is the functional group consisting of a methyl group bound to oxygen.
A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3.
Methylenedioxy is the term used in the field of chemistry, particularly in organic chemistry, for a functional group with the structural formula R-O-CH2-O-R' which is connected to the rest of a molecule by two chemical bonds.
Methylone (also known as "3,4-methylenedioxy-N-methylcathinone", "MDMC", "βk-MDMA" and by the slang term "M1") is an empathogen and stimulant psychoactive drug.
Methylphenidate, sold under various trade names, Ritalin being one of the most commonly known, is a central nervous system (CNS) stimulant of the phenethylamine and piperidine classes that is used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy.
In organic chemistry, a moiety is a part of a molecule.
Monoamine neurotransmitters are neurotransmitters and neuromodulators that contain one amino group that is connected to an aromatic ring by a two-carbon chain (such as -CH2-CH2-). All monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, tryptophan, and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes.
A monoamine releasing agent (MRA), or simply monoamine releaser, is a drug that induces the release of a monoamine neurotransmitter from the presynaptic neuron into the synapse, leading to an increase in the extracellular concentrations of the neurotransmitter.
N,N-Dimethylphenethylamine (N,N-DMPEA) is a substituted phenethylamine that is used as a flavoring agent.
N-Methylphenethylamine (NMPEA) is a naturally occurring trace amine neuromodulator in humans that is derived from the trace amine, phenethylamine (PEA).
NBOMe-mescaline or mescaline-NBOMe is a synthetic substituted phenethylamine.
Neurotoxins are toxins that are poisonous or destructive to nerve tissue (causing neurotoxicity).
Neurotransmitters are endogenous chemicals that enable neurotransmission.
Nitro compounds are organic compounds that contain one or more nitro functional groups (−2).
Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone and neurotransmitter.
A norepinephrine releasing agent (NRA), also known as an adrenergic releasing agent, is a catecholaminergic type of drug which induces the release of norepinephrine (noradrenaline) and epinephrine (adrenaline) from the pre-synaptic neuron into the synapse.
A norepinephrine–dopamine reuptake inhibitor (NDRI) is a drug that acts as a reuptake inhibitor for the neurotransmitters norepinephrine and dopamine by blocking the action of the norepinephrine transporter (NET) and the dopamine transporter (DAT), respectively.
Norfenefrine (INN) or meta-octopamine (3-octopamine), also known as 3,β-dihydroxyphenethylamine, is an adrenergic agent used as a sympathomimetic drug which is marketed in Europe, Japan, and Mexico.
Norfenfluramine, or 3-trifluoromethylamphetamine, is a never-marketed drug of the amphetamine family which behaves as a serotonin and norepinephrine releasing agent and potent 5-HT2A, 5-HT2B, and 5-HT2C agonist.
Octopamine is an organic chemical closely related to norepinephrine, and synthesized biologically by a homologous pathway.
In chemistry, an organic compound is generally any chemical compound that contains carbon.
Ortetamine (INN), also known as 2-methylamphetamine, is a stimulant drug of the amphetamine class.
Oxidopamine, also known as 6-hydroxydopamine (6-OHDA) or 2,4,5-trihydroxyphenethylamine, is a neurotoxic synthetic organic compound used by researchers to selectively destroy dopaminergic and noradrenergic neurons in the brain.
Phenelzine (Nardil, Nardelzine) is a non-selective and irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class which is used as an antidepressant and anxiolytic.
Phenethylamine (PEA) is an organic compound, natural monoamine alkaloid, and trace amine which acts as a central nervous system stimulant in humans.
Phentermine (contracted from phenyl-tertiary-butylamine), also known as α,α-dimethylphenethylamine, is a psychostimulant drug of the substituted amphetamine chemical class, with pharmacology similar to amphetamine.
In organic chemistry, the phenyl group or phenyl ring is a cyclic group of atoms with the formula C6H5.
Phenylephrine is a selective α1-adrenergic receptor agonist of the phenethylamine class used primarily as a decongestant, as an agent to dilate the pupil, to increase blood pressure, and to relieve hemorrhoids.
In organic chemistry, propyl is a three-carbon alkyl substituent with chemical formula – for the linear form.
Proscaline, or 4-propoxy-3,5-DMPEA, is a psychedelic and hallucinogenic drug, used by some as an entheogen.
Pseudoephedrine (PSE) is a sympathomimetic drug of the phenethylamine and amphetamine chemical classes.
Psychedelics are a class of drug whose primary action is to trigger psychedelic experiences via serotonin receptor agonism, causing thought and visual/auditory changes, and altered state of consciousness.
A psychoactive drug, psychopharmaceutical, or psychotropic is a chemical substance that changes brain function and results in alterations in perception, mood, consciousness, cognition, or behavior.
Recreational drug use is the use of a psychoactive drug to induce an altered state of consciousness for pleasure, by modifying the perceptions, feelings, and emotions of the user.
Salbutamol, also known as albuterol and marketed as Ventolin among other names, is a medication that opens up the medium and large airways in the lungs.
Selegiline, also known as L-deprenyl, is a substituted phenethylamine.
A serotonin releasing agent (SRA) is a type of drug that induces the release of serotonin into the neuronal synaptic cleft.
Stimulants (also often referred to as psychostimulants or colloquially as uppers) is an overarching term that covers many drugs including those that increase activity of the central nervous system and the body, drugs that are pleasurable and invigorating, or drugs that have sympathomimetic effects.
The structural formula of a chemical compound is a graphic representation of the molecular structure, showing how the atoms are arranged.
In organic chemistry and biochemistry, a substituent is an atom or group of atoms which replaces one or more hydrogen atoms on the parent chain of a hydrocarbon, becoming a moiety of the resultant new molecule.
Substituted amphetamines are a class of compounds based upon the amphetamine structure; it includes all derivative compounds which are formed by replacing, or substituting, one or more hydrogen atoms in the amphetamine core structure with substituents.
Substituted cathinones, which include some stimulants and entactogens, are derivatives of cathinone.
Substituted methylenedioxy- phenethylamines (MDxx) are a large chemical class of derivatives of the phenethylamines, which includes many psychoactive drugs that act as entactogens, psychedelics, and/or stimulants, as well as entheogens.
Substituted phenylmorpholines, or substituted phenmetrazines alternatively, are chemical derivatives of phenylmorpholine or of the psychostimulant drug phenmetrazine.
Substituted tryptamines, or serotonin analogues, are organic compounds which may be thought of as being derived from tryptamine itself.
Substitution reaction (also known as single displacement reaction or single substitution reaction) is a chemical reaction during which one functional group in a chemical compound is replaced by another functional group.
The prefix thio-, when applied to a chemical, such as an ion, means that an oxygen atom in the compound has been replaced by a sulfur atom.
Thyronamine refers both to a molecule, and to derivatives of that molecule: a family of decarboxylated and deiodinated metabolites of the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3).
Trace amines are an endogenous group of trace amine-associated receptor 1 (TAAR1) agonists – and hence, monoaminergic neuromodulators – that are structurally and metabolically related to classical monoamine neurotransmitters.
Trifluoromethyl is a functional group that has the formula -CF3.
Tyramine (also spelled tyramin), also known by several other names is a naturally occurring trace amine derived from the amino acid tyrosine.
Dimethoxybromoamphetamine (DOB), also known as brolamfetamine (INN) and bromo-DMA, is a psychedelic drug and substituted amphetamine of the phenethylamine class of compounds.
2,5-Dimethoxy-4-chloroamphetamine (DOC) is a psychedelic drug of the phenethylamine and amphetamine chemical classes.
2,5-Dimethoxy-4-iodoamphetamine (DOI) is a psychedelic drug and a substituted amphetamine.
2,5-Dimethoxy-4-methylamphetamine (DOM; known on the street as STP, standing for "Serenity, Tranquility and Peace") is a psychedelic and a substituted amphetamine.
2,5-Dimethoxy-4-nitroamphetamine (DON) is a recreational drug and amphetamine.
The 25-NB (25x-NBx) series, sometimes alternatively referred to as the NBOMe compounds, is a family of serotonergic psychedelics.
25B-NBOH (2C-B-NBOH, NBOH-2C-B) is a derivative of the phenethylamine derived hallucinogen 2C-B which has been sold as a designer drug.
25B-NBOMe (NBOMe-2C-B, Cimbi-36, Nova, BOM 2-CB) is a derivative of the phenethylamine psychedelic 2C-B, discovered in 2004 by Ralf Heim at the Free University of Berlin.
25-C-NBOH (2C-C-NBOH, NBOH-2CC) is a derivative of the phenethylamine derived hallucinogen 2C-C which has been sold as a designer drug.
25C-NBOMe (NBOMe-2C-C, 2C-C-NBOMe, Cimbi-82) is a psychedelic drug and derivative of the psychedelic phenethylamine 2C-C. 25C-NBOMe appeared on online vendor sites in 2010 but was not reported in the literature until 2011.
25D-NBOMe (or NBOMe-2C-D) is a derivative of the phenethylamine derived hallucinogen 2C-D. It acts in a similar manner to related compounds such as 25I-NBOMe, which is a potent agonist at the 5HT2A receptor.
25E-NBOMe (2C-E-NBOMe, NBOMe-2C-E) is a derivative of the phenethylamine 2C-E. It acts in a similar manner to related compounds such as 25I-NBOMe, which are potent agonists at the 5HT2A receptor.
25I-NBF (2C-I-NBF, NBF-2C-I, Cimbi-21) is a derivative of the phenethylamine hallucinogen 2C-I, which acts as a highly potent partial agonist for the human 5-HT2A receptor.
25I-NBOH (NBOH-2CI, Cimbi-27, 2-C-I-NBOH) is a derivative of the phenethylamine-derived hallucinogen 2C-I that was discovered in 2006 by a team at Purdue University.
25I-NBOMe (2C-I-NBOMe, Cimbi-5, also shortened to "25I") is a psychedelic hallucinogen that is used in biochemistry research for mapping the brains usage of the type 2A serotonin receptor and later also has been used for recreational purpose.
25P-NBOMe (2C-P-NBOMe, NBOMe-2C-P) is a derivative of the phenethylamine 2C-P. It acts in a similar manner to related compounds such as 25I-NBOMe, which are potent agonists at the 5HT2A receptor.
2C (2C-x) is a general name for the family of psychedelic phenethylamines containing methoxy groups on the 2 and 5 positions of a benzene ring.
2C-B or 2,5-dimethoxy-4-bromophenethylamine is a psychedelic drug of the 2C family.
2C-C is a psychedelic drug of the 2C family.
2C-D (2,5-dimethoxy-4-methylphenethylamine, also known as 2C-M) is a psychedelic drug of the 2C family that is sometimes used as an entheogen.
2C-E is a psychedelic phenethylamine of the 2C family.
2C-F, or 4-fluoro-2,5-dimethoxyphenethylamine, is a lesser-known psychedelic drug of the 2C family.
2C-I is a psychedelic phenethylamine of the 2C family.
2C-N, or 2,5-dimethoxy-4-nitrophenethylamine, is a psychedelic phenethylamine of the 2C family.
2C-P is a relatively potent and long acting psychedelic phenethylamine and 2C compound first synthesized by Alexander Shulgin.
2C-T-19 or 2,5-dimethoxy-4-butylthiophenethylamine is a psychedelic phenethylamine of the 2C family.
2C-T-2 is a psychedelic and entactogenic phenethylamine of the 2C family.
2C-T-21 is a psychedelic phenethylamine of the 2C family.
2C-T-4 (2,5-dimethoxy-4-isopropylthiophenethylamine) is a psychedelic phenethylamine of the 2C family.
2C-T-7 is a psychedelic phenethylamine of the 2C family.
2C-T-8 is a psychedelic phenethylamine of the 2C family.
3,4-Methylenedioxy-N-ethylamphetamine ("MDEA"; also called "MDE" and colloquially, "Eve") is an empathogenic psychoactive drug.
3,4-Methylenedioxyamphetamine (MDA), is an empathogen-entactogen, psychostimulant, and psychedelic drug of the amphetamine family that is encountered mainly as a recreational drug.
3-Iodothyronamine (T1AM) is an endogenous thyronamine.
5-APB (abbreviation of "5-(2-aminopropyl)benzofuran"; see infobox for the correct IUPAC name) is an empathogenic psychoactive compound of the substituted benzofuran, substituted amphetamine and substituted phenethylamine classes.
6-APB (6-(2-aminopropyl)benzofuran) is an empathogenic psychoactive compound of the substituted benzofuran, substituted amphetamine and substituted phenethylamine classes.
Adrenaline analog, Adrenaline analogue, Catecholamine analog, Catecholamine analogue, Dopamine analog, Dopamine analogue, Epinephrine analog, Epinephrine analogue, Noradrenaline analog, Noradrenaline analogue, Norepinephrine analog, Norepinephrine analogue, Phenethylamine class, Phenethylamines, Substituted Phenethylamine, Substituted phenethylamines.