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Sumatriptan

Index Sumatriptan

Sumatriptan, sold under the brand name Imitrex among others, is a medication used to treat migraine headaches and cluster headaches. [1]

Table of Contents

  1. 59 relations: Agonist, American Academy of Neurology, Autoinjector, Bioavailability, Breastfeeding, Calcitonin gene-related peptide, Chest pain, Cluster headache, Coronary vasospasm, Dr. Reddy's Laboratories, Electrophoresis, Endo International, Feces, First pass effect, Generic drug, Glucuronic acid, Headache (journal), Hemoglobin, Integrated circuit, Iontophoresis, Jet injector, Medication, Medication overuse headache, Migraine, Monoamine oxidase, Monoamine oxidase inhibitor, Mylan, Myocardial infarction, N,N-Dimethyltryptamine, Nasal administration, Nasal spray, Novartis, Oral administration, Pregnancy, Ranbaxy Laboratories, Seizure, Serotonin, Serotonin reuptake inhibitor, Serotonin syndrome, Stroke, Subcutaneous administration, Succinic acid, Sulfhemoglobinemia, Sulfur, Sumatriptan/naproxen, Transdermal, Transdermal patch, Trigeminal nerve, Triptan, Urine, ... Expand index (9 more) »

  2. 5-HT1B agonists
  3. 5-HT1D agonists
  4. 5-HT1F agonists
  5. Triptans

Agonist

An agonist is a chemical that activates a receptor to produce a biological response.

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American Academy of Neurology

The American Academy of Neurology (AAN) is a professional society representing over 40,000 neurologists and neuroscientists.

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Autoinjector

An autoinjector (or auto-injector) is a medical device designed to deliver a dose of a particular drug.

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Bioavailability

In pharmacology, bioavailability is a subcategory of absorption and is the fraction (%) of an administered drug that reaches the systemic circulation.

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Breastfeeding

Breastfeeding, variously known as chestfeeding or nursing, is the process where breast milk is fed to a child.

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Calcitonin gene-related peptide (CGRP) is a member of the calcitonin family of peptides consisting of calcitonin, amylin, adrenomedullin, adrenomedullin 2 (intermedin) and calcitonin‑receptor‑stimulating peptide.

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Chest pain

Chest pain is pain or discomfort in the chest, typically the front of the chest.

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Cluster headache

Cluster headache is a neurological disorder characterized by recurrent severe headaches on one side of the head, typically around the eye(s).

See Sumatriptan and Cluster headache

Coronary vasospasm

Coronary vasospasm refers to when a coronary artery suddenly undergoes either complete or sub-total temporary occlusion.

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Dr. Reddy's Laboratories

Dr.

See Sumatriptan and Dr. Reddy's Laboratories

Electrophoresis

Electrophoresis is the motion of charged dispersed particles or dissolved charged molecules relative to a fluid under the influence of a spatially uniform electric field.

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Endo International

Endo International plc is an American Irish-domiciled generics and specialty branded pharmaceutical company that generated over 93% of its 2017 sales from the U.S. healthcare system.

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Feces

Feces (or faeces;: faex) are the solid or semi-solid remains of food that was not digested in the small intestine, and has been broken down by bacteria in the large intestine.

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First pass effect

The first pass effect (also known as first-pass metabolism or presystemic metabolism) is a phenomenon of drug metabolism at a specific location in the body which leads to a reduction in the concentration of the active drug before it reaches the site of action or systemic circulation.

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Generic drug

A generic drug (or simply generic) is a pharmaceutical drug that contains the same chemical substance as a drug that was originally protected by chemical patents.

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Glucuronic acid

Glucuronic acid (from Greek γλεῦκος "sweet wine, must" and οὖρον "urine") is a uronic acid that was first isolated from urine (hence the name "uronic acid").

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Headache (journal)

Headache: The Journal of Head and Face Pain is a peer-reviewed medical journal covering all aspects of head and face pain.

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Hemoglobin

Hemoglobin (haemoglobin, Hb or Hgb) is a protein containing iron that facilitates the transport of oxygen in red blood cells.

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Integrated circuit

An integrated circuit (IC), also known as a microchip, computer chip, or simply chip, is a small electronic device made up of multiple interconnected electronic components such as transistors, resistors, and capacitors.

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Iontophoresis

Iontophoresis is a process of transdermal drug delivery by use of a voltage gradient on the skin.

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Jet injector

A jet injector is a type of medical injecting syringe device used for a method of drug delivery known as jet injection.

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Medication

A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease.

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Medication overuse headache

A medication overuse headache (MOH), also known as a rebound headache, usually occurs when painkillers are taken frequently to relieve headaches.

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Migraine

Migraine is a genetically influenced complex neurological disorder characterized by episodes of moderate-to-severe headache, most often unilateral and generally associated with nausea and light and sound sensitivity.

See Sumatriptan and Migraine

Monoamine oxidase

Monoamine oxidases (MAO) are a family of enzymes that catalyze the oxidation of monoamines, employing oxygen to clip off their amine group.

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Monoamine oxidase inhibitor

Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B).

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Mylan

Mylan N.V. was a global generic and specialty pharmaceuticals company.

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Myocardial infarction

A myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops in one of the coronary arteries of the heart, causing infarction (tissue death) to the heart muscle.

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N,N-Dimethyltryptamine

N,N-Dimethyltryptamine (DMT or N,N-DMT) is a substituted tryptamine that occurs in many plants and animals, including humans, and which is both a derivative and a structural analog of tryptamine. Sumatriptan and n,N-Dimethyltryptamine are Dimethylamino compounds.

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Nasal administration

Nasal administration, popularly known as snorting, is a route of administration in which drugs are insufflated through the nose.

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Nasal spray

Nasal sprays are used to deliver medications locally in the nasal cavities or systemically.

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Novartis

Novartis AG is a Swiss multinational pharmaceutical corporation based in Basel, Switzerland.

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Oral administration

| name.

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Pregnancy

Pregnancy is the time during which one or more offspring develops (gestates) inside a woman's uterus (womb).

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Ranbaxy Laboratories

Ranbaxy Laboratories Limited was an Indian multinational pharmaceutical company that was incorporated in India in 1961 and remained an entity until 2014.

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Seizure

A seizure is a period of symptoms due to abnormally excessive or synchronous neuronal activity in the brain.

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Serotonin

Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.

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Serotonin reuptake inhibitor

A serotonin reuptake inhibitor (SRI) is a type of drug which acts as a reuptake inhibitor of the neurotransmitter serotonin (5-hydroxytryptamine, or 5-HT) by blocking the action of the serotonin transporter (SERT).

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Serotonin syndrome

Serotonin syndrome (SS) is a group of symptoms that may occur with the use of certain serotonergic medications or drugs.

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Stroke

Stroke (also known as a cerebrovascular accident (CVA) or brain attack) is a medical condition in which poor blood flow to the brain causes cell death.

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Subcutaneous administration

Subcutaneous administration is the insertion of medications beneath the skin either by injection or infusion.

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Succinic acid

Succinic acid is a dicarboxylic acid with the chemical formula (CH2)2(CO2H)2.

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Sulfhemoglobinemia

Sulfhemoglobinemia is a rare condition in which there is excess sulfhemoglobin (SulfHb) in the blood.

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Sulfur

Sulfur (also spelled sulphur in British English) is a chemical element; it has symbol S and atomic number 16.

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Sumatriptan/naproxen

Sumatriptan/naproxen, sold under the brand name Treximet among others, is a fixed-dose combination medication used to treat migraines.

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Transdermal

Transdermal is a route of administration wherein active ingredients are delivered across the skin for systemic distribution.

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Transdermal patch

A transdermal patch is a medicated adhesive patch that is placed on the skin to deliver a specific dose of medication through the skin and into the bloodstream.

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Trigeminal nerve

In neuroanatomy, the trigeminal nerve (lit. triplet nerve), also known as the fifth cranial nerve, cranial nerve V, or simply CN V, is a cranial nerve responsible for sensation in the face and motor functions such as biting and chewing; it is the most complex of the cranial nerves.

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Triptan

Triptans are a family of tryptamine-based drugs used as abortive medication in the treatment of migraines and cluster headaches. Sumatriptan and Triptan are 5-HT1D agonists and Triptans.

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Urine

Urine is a liquid by-product of metabolism in humans and in many other animals.

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Vasoconstriction

Vasoconstriction is the narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels, in particular the large arteries and small arterioles.

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Ventricular fibrillation

Ventricular fibrillation (V-fib or VF) is an abnormal heart rhythm in which the ventricles of the heart quiver.

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Ventricular tachycardia

Ventricular tachycardia (V-tach or VT) is a cardiovascular disorder in which fast heart rate occurs in the ventricles of the heart.

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Vertigo

Vertigo is a condition in which a person has the sensation that they are moving, or that objects around them are moving, when they are not.

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Voltage

Voltage, also known as (electrical) potential difference, electric pressure, or electric tension is the difference in electric potential between two points.

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WHO Model List of Essential Medicines

The WHO Model List of Essential Medicines (aka Essential Medicines List or EML), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system. Sumatriptan and WHO Model List of Essential Medicines are World Health Organization essential medicines.

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5-HT receptor

5-HT receptors, 5-hydroxytryptamine receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems.

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5-HT1B receptor

5-hydroxytryptamine receptor 1B also known as the 5-HT1B receptor is a protein that in humans is encoded by the HTR1B gene.

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5-HT1D receptor

5-hydroxytryptamine (serotonin) receptor 1D, also known as HTR1D, is a 5-HT receptor, but also denotes the human gene encoding it.

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See also

5-HT1B agonists

5-HT1D agonists

5-HT1F agonists

Triptans

References

[1] https://en.wikipedia.org/wiki/Sumatriptan

Also known as ATC code N02CC01, ATCvet code QN02CC01, C14H21N3O2S, Crotaphos, Emetrex, Helvemigran, Imigran, Imigran recovery, Imitrex, Sumatran (drug), Sumatriptan succinate, Sumavel Dosepro, Sumax, Sumotriptan, Zelrix, Zembrace Symtouch.

, Vasoconstriction, Ventricular fibrillation, Ventricular tachycardia, Vertigo, Voltage, WHO Model List of Essential Medicines, 5-HT receptor, 5-HT1B receptor, 5-HT1D receptor.