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T-47D

Index T-47D

T-47D is a human breast cancer cell line commonly used in biomedical research involving the hormonal expression of cancer cells. [1]

14 relations: Angiogenesis, Breast cancer, Ductal carcinoma, Estradiol, Estrogen, Hormone, Immortalised cell line, Mammary gland, Pleural effusion, Progesterone, Progesterone receptor, Severe combined immunodeficient mice, Transcription (biology), Xenotransplantation.

Angiogenesis

Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels.

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Breast cancer

Breast cancer is cancer that develops from breast tissue.

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Ductal carcinoma

Ductal carcinoma is a type of tumor that primarily presents in the ducts of a gland.

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Estradiol

Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone.

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Estrogen

Estrogen, or oestrogen, is the primary female sex hormone.

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Hormone

A hormone (from the Greek participle “ὁρμῶ”, "to set in motion, urge on") is any member of a class of signaling molecules produced by glands in multicellular organisms that are transported by the circulatory system to target distant organs to regulate physiology and behaviour.

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Immortalised cell line

An immortalized cell line is a population of cells from a multicellular organism which would normally not proliferate indefinitely but, due to mutation, have evaded normal cellular senescence and instead can keep undergoing division.

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Mammary gland

A mammary gland is an exocrine gland in mammals that produces milk to feed young offspring.

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Pleural effusion

A pleural effusion is excess fluid that accumulates in the pleural cavity, the fluid-filled space that surrounds the lungs.

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Progesterone

Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species.

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Progesterone receptor

The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found inside cells.

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Severe combined immunodeficient mice

Mice with severe combined immunodeficiency (SCIDs) are often used in the research of human disease.

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Transcription (biology)

Transcription is the first step of gene expression, in which a particular segment of DNA is copied into RNA (especially mRNA) by the enzyme RNA polymerase.

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Xenotransplantation

Xenotransplantation (xenos- from the Greek meaning "foreign"), is the transplantation of living cells, tissues or organs from one species to another.

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Redirects here:

T47-D, T47D.

References

[1] https://en.wikipedia.org/wiki/T-47D

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