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Index T-Coffee

T-Coffee (Tree-based Consistency Objective Function for Alignment Evaluation) is a multiple sequence alignment software using a progressive approach. [1]

15 relations: Clustal, Desmond G. Higgins, FASTA format, GNU General Public License, Linux, List of sequence alignment software, MacOS, MAFFT, Microsoft Windows, Multiple sequence alignment, MUSCLE (alignment software), ProbCons, Protein Data Bank, Protein Information Resource, Unix.


Clustal is a series of widely used computer programs used in Bioinformatics for multiple sequence alignment.

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Desmond G. Higgins

Desmond Gerard Higgins is a Professor of Bioinformatics at University College Dublin, widely known for CLUSTAL, a series of computer programs for performing multiple sequence alignment.

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FASTA format

In bioinformatics, FASTA format is a text-based format for representing either nucleotide sequences or peptide sequences, in which nucleotides or amino acids are represented using single-letter codes.

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GNU General Public License

The GNU General Public License (GNU GPL or GPL) is a widely used free software license, which guarantees end users the freedom to run, study, share and modify the software.

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Linux is a family of free and open-source software operating systems built around the Linux kernel.

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List of sequence alignment software

This list of sequence alignment software is a compilation of software tools and web portals used in pairwise sequence alignment and multiple sequence alignment.

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macOS (previously and later) is a series of graphical operating systems developed and marketed by Apple Inc. since 2001.

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In bioinformatics, MAFFT (for multiple alignment using fast Fourier transform) is a program used to create multiple sequence alignments of amino acid or nucleotide sequences. Published in 2002, the first version of MAFFT used an algorithm based on progressive alignment, in which the sequences were clustered with the help of the Fast Fourier Transform.

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Microsoft Windows

Microsoft Windows is a group of several graphical operating system families, all of which are developed, marketed, and sold by Microsoft.

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Multiple sequence alignment

A multiple sequence alignment (MSA) is a sequence alignment of three or more biological sequences, generally protein, DNA, or RNA.

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MUSCLE (alignment software)

MUltiple Sequence Comparison by Log-Expectation (MUSCLE) is computer software for multiple sequence alignment of protein and nucleotide sequences.

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ProbCons is an open source probabilistic consistency-based multiple alignment of amino acid sequences.

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Protein Data Bank

The Protein Data Bank (PDB) is a crystallographic database for the three-dimensional structural data of large biological molecules, such as proteins and nucleic acids.

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Protein Information Resource

The Protein Information Resource (PIR), located at Georgetown University Medical Center (GUMC), is an integrated public bioinformatics resource to support genomic and proteomic research, and scientific studies.

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Unix (trademarked as UNIX) is a family of multitasking, multiuser computer operating systems that derive from the original AT&T Unix, development starting in the 1970s at the Bell Labs research center by Ken Thompson, Dennis Ritchie, and others.

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[1] https://en.wikipedia.org/wiki/T-Coffee

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