34 relations: Apical ectodermal ridge, Brachyury, Dun gene, Fibroblast growth factor, Finger, Gene expression, Heart, Holt–Oram syndrome, Homeobox, Hox gene, Limb bud, Limb development, T-box, TBR1, TBX1, TBX15, TBX19, TBX2, TBX20, TBX21, TBX22, TBX3, TBX4, TBX5 (gene), TBX6, Thumb, Transcription factor, Ulnar–mammary syndrome, Ventricle (heart), Ventricular septal defect, W-box, Wnt signaling pathway, X-ray crystallography, Zone of polarizing activity.
Apical ectodermal ridge
The apical ectodermal ridge (AER) is a structure that forms from the ectodermal cells at the distal end of each limb bud and acts as a major signaling center to ensure proper development of a limb.
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Brachyury
Brachyury is a protein that in humans is encoded by the T gene.
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Dun gene
The dun gene is a dilution gene that affects both red and black pigments in the coat color of a horse.
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Fibroblast growth factor
The fibroblast growth factors are a family of cell signalling proteins that are involved in a wide variety of processes, most notably as crucial elements for normal development.
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Finger
A finger is a limb of the human body and a type of digit, an organ of manipulation and sensation found in the hands of humans and other primates.
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Gene expression
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product.
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Heart
The heart is a muscular organ in most animals, which pumps blood through the blood vessels of the circulatory system.
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Holt–Oram syndrome
Holt–Oram syndrome (also called atrio-digital syndrome, atriodigital dysplasia, cardiac-limb syndrome, heart-hand syndrome type 1, HOS, ventriculo-radial syndrome) is an autosomal dominant disorder that affects bones in the arms and hands (the upper limbs) and often causes heart problems.
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Homeobox
A homeobox is a DNA sequence, around 180 base pairs long, found within genes that are involved in the regulation of patterns of anatomical development (morphogenesis) in animals, fungi and plants.
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Hox gene
Hox genes, a subset of homeotic genes, are a group of related genes that control the body plan of an embryo along the head-tail axis.
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Limb bud
The limb bud is a structure formed early in vertebrate limb development.
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Limb development
Limb development in vertebrates is an area of active research in both developmental and evolutionary biology, with much of the latter work focused on the transition from fin to limb.
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T-box
T-box refers to a group of transcription factors involved in limb and heart development.
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TBR1
T-box, brain, 1 is a transcription factor protein important in vertebrate embryo development.
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TBX1
T-box transcription factor TBX1 also known as T-box protein 1 and testis-specific T-box protein is a protein that in humans is encoded by the TBX1 gene.
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TBX15
TBX15 or T-Box 15 is a transcription factor involved in many developmental processes.
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TBX19
T-box transcription factor TBX19 is a protein that in humans is encoded by the TBX19 gene.
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TBX2
T-box transcription factor 2 Tbx2 is a transcription factor that is encoded by the Tbx2 gene on chromosome 17q21-22 in humans.
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TBX20
TBX20 (gene) is a member of the T-box family that encodes the transcription factor TBX20.
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TBX21
T-box transcription factor TBX21 is a protein that in humans is encoded by the TBX21 gene.
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TBX22
T-box transcription factor TBX22 is a protein that in humans is encoded by the TBX22 gene.
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TBX3
T-box transcription factor TBX3 is a protein that in humans is encoded by the TBX3 gene.
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TBX4
T-box transcription factor Tbx4 is a transcription factor that belongs to T-box gene family that is involved in the regulation of embryonic developmental processes.
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TBX5 (gene)
T-box transcription factor TBX5 is a protein that in humans is encoded by the TBX5 gene.
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TBX6
T-box 6 is a protein that in humans is encoded by the TBX6 gene.
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Thumb
The thumb is the first digit of the hand.
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Transcription factor
In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.
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Ulnar–mammary syndrome
Ulnar–mammary syndrome or Schinzel syndrome is a cutaneous condition characterized by nipple and breast hypoplasia or aplasia.
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Ventricle (heart)
A ventricle is one of two large chambers in the heart that collect and expel blood received from an atrium towards the peripheral beds within the body and lungs.
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Ventricular septal defect
A ventricular septal defect (VSD) is a defect in the ventricular septum, the wall dividing the left and right ventricles of the heart.
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W-box
The W box is a deoxyribonucleic acid (DNA) cis-regulatory element sequence, (T)TGAC(C/T), which is recognized by the family of WRKY transcription factors.
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Wnt signaling pathway
The Wnt signaling pathways are a group of signal transduction pathways made of proteins that pass signals into a cell through cell surface receptors.
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X-ray crystallography
X-ray crystallography is a technique used for determining the atomic and molecular structure of a crystal, in which the crystalline atoms cause a beam of incident X-rays to diffract into many specific directions.
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Zone of polarizing activity
The zone of polarizing activity (ZPA) is an area of mesenchyme that contains signals which instruct the developing limb bud to form along the anterior/posterior axis.
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References
[1] https://en.wikipedia.org/wiki/T-box