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T4 rII system

Index T4 rII system

The T4 rII system is an experimental system developed in the 1950s by Seymour Benzer for studying the substructure of the gene. [1]

31 relations: Cistron, Crick, Brenner et al. experiment, Deletion (genetics), DNA, Enterobacteria phage T4, Escherichia coli, Experimental system, Francis Crick, Gene, Genetic code, Genetic linkage, Genetic recombination, Hybrid (biology), James Watson, Locus (genetics), Max Delbrück, Missense mutation, Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid, Mutant, Nonsense mutation, Nucleic acid sequence, Peptide, Phage group, Point mutation, Ramamirtha Jayaraman, Richard Feynman, Seymour Benzer, Strain (biology), Synthesis-dependent strand annealing, Viral plaque, Wild type.

Cistron

A cistron is an alternative term to a gene.

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Crick, Brenner et al. experiment

The Crick, Brenner et al.

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Deletion (genetics)

In genetics, a deletion (also called gene deletion, deficiency, or deletion mutation) (sign: Δ) is a mutation (a genetic aberration) in which a part of a chromosome or a sequence of DNA is lost during DNA replication.

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DNA

Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.

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Enterobacteria phage T4

Enterobacteria phage T4 is a bacteriophage that infects Escherichia coli bacteria.

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Escherichia coli

Escherichia coli (also known as E. coli) is a Gram-negative, facultatively anaerobic, rod-shaped, coliform bacterium of the genus Escherichia that is commonly found in the lower intestine of warm-blooded organisms (endotherms).

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Experimental system

In scientific research, an experimental system is the physical, technical and procedural basis for an experiment or series of experiments.

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Francis Crick

Francis Harry Compton Crick (8 June 1916 – 28 July 2004) was a British molecular biologist, biophysicist, and neuroscientist, most noted for being a co-discoverer of the structure of the DNA molecule in 1953 with James Watson, work which was based partly on fundamental studies done by Rosalind Franklin, Raymond Gosling and Maurice Wilkins.

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Gene

In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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Genetic code

The genetic code is the set of rules used by living cells to translate information encoded within genetic material (DNA or mRNA sequences) into proteins.

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Genetic linkage

Genetic linkage is the tendency of DNA sequences that are close together on a chromosome to be inherited together during the meiosis phase of sexual reproduction.

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Genetic recombination

Genetic recombination (aka genetic reshuffling) is the production of offspring with combinations of traits that differ from those found in either parent.

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Hybrid (biology)

In biology, a hybrid, or crossbreed, is the result of combining the qualities of two organisms of different breeds, varieties, species or genera through sexual reproduction.

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James Watson

James Dewey Watson (born April 6, 1928) is an American molecular biologist, geneticist and zoologist, best known as one of the co-discoverers of the structure of DNA in 1953 with Francis Crick and Rosalind Franklin.

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Locus (genetics)

A locus (plural loci) in genetics is a fixed position on a chromosome, like the position of a gene or a marker (genetic marker).

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Max Delbrück

Max Ludwig Henning Delbrück (September 4, 1906 – March 9, 1981), a German–American biophysicist, helped launch the molecular biology research program in the late 1930s.

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Missense mutation

In genetics, a missense mutation is a point mutation in which a single nucleotide change results in a codon that codes for a different amino acid.

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Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid

"Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid" was the first article published to describe the discovery of the double helix structure of DNA, using X-ray diffraction and the mathematics of a helix transform.

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Mutant

In biology and especially genetics, a mutant is an organism or a new genetic character arising or resulting from an instance of mutation, which is an alteration of the DNA sequence of a gene or chromosome of an organism.

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Nonsense mutation

In genetics, a point-nonsense mutation is a point mutation in a sequence of DNA that results in a premature stop codon, or a point-nonsense codon in the transcribed mRNA, and in a truncated, incomplete, and usually nonfunctional protein product.

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Nucleic acid sequence

A nucleic acid sequence is a succession of letters that indicate the order of nucleotides forming alleles within a DNA (using GACT) or RNA (GACU) molecule.

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Peptide

Peptides (from Gr.: πεπτός, peptós "digested"; derived from πέσσειν, péssein "to digest") are short chains of amino acid monomers linked by peptide (amide) bonds.

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Phage group

The phage group (sometimes called the American Phage Group) was an informal network of biologists centered on Max Delbrück that contributed heavily to bacterial genetics and the origins of molecular biology in the mid-20th century.

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Point mutation

A point mutation is a genetic mutation where a single nucleotide base is changed, inserted or deleted from a sequence of DNA or RNA.

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Ramamirtha Jayaraman

Ramamirtha Jayaraman (born 1937) is an Indian geneticist, known for his studies on bacteria, especially on Escherichia coli.

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Richard Feynman

Richard Phillips Feynman (May 11, 1918 – February 15, 1988) was an American theoretical physicist, known for his work in the path integral formulation of quantum mechanics, the theory of quantum electrodynamics, and the physics of the superfluidity of supercooled liquid helium, as well as in particle physics for which he proposed the parton model.

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Seymour Benzer

Seymour Benzer (October 15, 1921 – November 30, 2007) was an American physicist, molecular biologist and behavioral geneticist.

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Strain (biology)

In biology, a strain is a low-level taxonomic rank used at the intraspecific level (within a species).

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Synthesis-dependent strand annealing

In genetics, the initial processes involved in repair of a double-strand break by synthesis-dependent strand annealing (SDSA) are identical to those in the double Holliday junction model, and have been most extensively studied in yeast species Saccharomyces cerevisiae.

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Viral plaque

A viral plaque is a visible structure formed within a cell culture, such as bacterial cultures within some nutrient medium (e.g. agar).

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Wild type

Wild type (WT) refers to the phenotype of the typical form of a species as it occurs in nature.

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Redirects here:

Benzer test, RII system.

References

[1] https://en.wikipedia.org/wiki/T4_rII_system

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